𝕏

Task 55840119

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_102_0
Workunit 26516703
Created 3 Jul 2024, 5:06:33 UTC
Sent 3 Jul 2024, 6:19:54 UTC
Report deadline 6 Jul 2024, 15:55:54 UTC
Received 3 Jul 2024, 16:11:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 229363
Run time 2 hours 42 min 54 sec
CPU time 2 hours 42 min 31 sec
Validate state Valid
Credit 64.31
Device peak FLOPS 3.29 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.95 MB
Peak swap size 6.39 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_102.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_102_0_r1917147446_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_102_0_r1917147446_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.871151
     * GNaL_b in INaL: 0.005747
     * Gto_b in Ito: 0.086198
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032393
     * GKs_b in IKs: 0.001956
     * GK1_b in IK1: 0.164330
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.464845
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028812
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13056124, states[0] = 7.386199, states[40]= 0.004822
Saving checkpoint... 
Iteration: 26071475, states[0] = 0.468014, states[40]= 0.004335
Saving checkpoint... 
Iteration: 39291601, states[0] = -94.977853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51705352, states[0] = -94.850188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64603589, states[0] = -24.714679, states[40]= 0.000713
Saving checkpoint... 
Iteration: 77418929, states[0] = -95.015417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90181737, states[0] = -94.779258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102867370, states[0] = -94.993178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115726812, states[0] = -94.868387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128528788, states[0] = 18.783847, states[40]= 0.006188
Saving checkpoint... 
Iteration: 141076270, states[0] = -0.886624, states[40]= 0.004130
Saving checkpoint... 
Iteration: 153830707, states[0] = -94.971476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166608060, states[0] = -28.126953, states[40]= 0.000553
Saving checkpoint... 
Iteration: 179684351, states[0] = -94.780354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192527398, states[0] = 19.201164, states[40]= 0.006436
Saving checkpoint... 
Iteration: 205240552, states[0] = -94.886169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218074933, states[0] = -0.060963, states[40]= 0.004243
Saving checkpoint... 
Iteration: 230745303, states[0] = -94.892659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243672773, states[0] = -94.666170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257014646, states[0] = 21.909013, states[40]= 0.019538
Saving checkpoint... 
Iteration: 269700399, states[0] = -94.816133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282465891, states[0] = -95.014204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295035860, states[0] = 16.567645, states[40]= 0.005440
Saving checkpoint... 
Iteration: 307848408, states[0] = -94.979673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320437169, states[0] = -95.008845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333197806, states[0] = -94.810712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345853040, states[0] = -94.981841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358827785, states[0] = -94.968544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371619947, states[0] = -39.616360, states[40]= 0.000136
Saving checkpoint... 
Iteration: 383778668, states[0] = -94.930980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396293784, states[0] = -94.944548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408644661, states[0] = -67.067946, states[40]= 0.000002
Saving checkpoint... 
Iteration: 421218958, states[0] = -94.851377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433768575, states[0] = -94.920644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446303775, states[0] = -94.952417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458299920, states[0] = -94.949453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470634627, states[0] = -55.168990, states[40]= 0.000012
Saving checkpoint... 
Iteration: 483070143, states[0] = 2.528921, states[40]= 0.004530
Saving checkpoint... 
Iteration: 495762376, states[0] = -94.913728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508712314, states[0] = -94.839260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521268917, states[0] = -94.920953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534183627, states[0] = -94.777411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546672446, states[0] = -94.655109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559377731, states[0] = -94.991922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571908377, states[0] = -95.001704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584456970, states[0] = -95.012480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597080079, states[0] = -3.242564, states[40]= 0.003739
Saving checkpoint... 
Iteration: 609363133, states[0] = -94.986135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622158867, states[0] = -89.244644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634791997, states[0] = -94.942891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647018515, states[0] = 21.262274, states[40]= 0.011102
Saving checkpoint... 
Iteration: 659728479, states[0] = -94.867278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672231509, states[0] = -94.872082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684488267, states[0] = -95.017170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696967060, states[0] = -95.014095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709296181, states[0] = -94.946309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721784755, states[0] = -94.936474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734176114, states[0] = -94.732210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746251332, states[0] = -94.900176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758675622, states[0] = -94.725792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770469436, states[0] = -95.014421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782981278, states[0] = -95.016162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795649438, states[0] = -73.868539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808550630, states[0] = 11.098115, states[40]= 0.004945
Saving checkpoint... 
Iteration: 821309286, states[0] = -94.956201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834040532, states[0] = 14.922175, states[40]= 0.005189
Saving checkpoint... 
Iteration: 846360026, states[0] = -94.984648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858869211, states[0] = -94.988463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871552642, states[0] = 10.300660, states[40]= 0.004918
Saving checkpoint... 
Iteration: 883948027, states[0] = -95.010646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896381574, states[0] = -94.993087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908789857, states[0] = -94.940879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921440698, states[0] = -95.009174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933755277, states[0] = -94.905008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946355467, states[0] = -94.982556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958767473, states[0] = -94.919106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971305254, states[0] = -94.953173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983608078, states[0] = -28.100001, states[40]= 0.000554
Saving checkpoint... 
Iteration: 996141678, states[0] = -63.306386, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1008354081, states[0] = -94.981881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020997267, states[0] = -95.018075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033552018, states[0] = 10.549426, states[40]= 0.004926
Saving checkpoint... 
Iteration: 1046041612, states[0] = 14.528015, states[40]= 0.005148
Saving checkpoint... 
Iteration: 1058671258, states[0] = -94.606289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071149413, states[0] = -73.829246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083897328, states[0] = -94.998155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096510512, states[0] = 22.697583, states[40]= 0.046823
Saving checkpoint... 
Iteration: 1109320967, states[0] = -94.963863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122020929, states[0] = 20.788466, states[40]= 0.008853
Saving checkpoint... 
Iteration: 1134823772, states[0] = -94.965601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147258201, states[0] = -94.908413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160136471, states[0] = -57.233734, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1172735242, states[0] = -94.877486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185363994, states[0] = -94.986117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197734025, states[0] = -94.875622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210409562, states[0] = -95.001608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222811988, states[0] = -94.957834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235294099, states[0] = -94.944254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247727576, states[0] = -94.865426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260170427, states[0] = -94.560447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272624368, states[0] = -44.116901, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1285043505, states[0] = 13.827123, states[40]= 0.005087
Saving checkpoint... 
Iteration: 1297722905, states[0] = -94.857626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310440177, states[0] = -95.008811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322817081, states[0] = -94.961210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335314170, states[0] = -94.959255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347665680, states[0] = -93.907327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360201096, states[0] = -94.816794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372597119, states[0] = -17.656764, states[40]= 0.001158
Saving checkpoint... 
Iteration: 1384984186, states[0] = -95.016165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397495286, states[0] = -95.017587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410032975, states[0] = 17.525291, states[40]= 0.005674
Saving checkpoint... 
Iteration: 1422745179, states[0] = -94.891586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435267974, states[0] = -94.919333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448062974, states[0] = 5.946291, states[40]= 0.004763
Saving checkpoint... 
Iteration: 1460409878, states[0] = -95.001529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473212993, states[0] = -94.839884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485657079, states[0] = -86.702864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498513757, states[0] = 22.051235, states[40]= 0.023105
Saving checkpoint... 
Iteration: 1511078864, states[0] = -95.233720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523478132, states[0] = -13.268822, states[40]= 0.001942
Saving checkpoint... 
Iteration: 1535819920, states[0] = -61.773295, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1548415158, states[0] = -56.248577, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1560728206, states[0] = -75.213888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573301478, states[0] = -40.411101, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1585911837, states[0] = -52.877005, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1598605324, states[0] = -95.188992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611177177, states[0] = -95.131414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623696725, states[0] = -35.395865, states[40]= 0.000244
Saving checkpoint... 
Iteration: 1636447955, states[0] = -95.251755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648877915, states[0] = -14.702633, states[40]= 0.001704
Saving checkpoint... 
Iteration: 1661315114, states[0] = -95.208208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673917345, states[0] = -95.211857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686841983, states[0] = -95.245570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699375711, states[0] = -95.129742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712375120, states[0] = -95.278612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725208826, states[0] = -95.198072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738167180, states[0] = -95.271778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750950715, states[0] = -95.006997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763637219, states[0] = -95.239853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776207817, states[0] = -95.196326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788993540, states[0] = -31.947708, states[40]= 0.000370
Saving checkpoint... 
Iteration: 1801627979, states[0] = -53.036309, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1814452645, states[0] = -95.055308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826823162, states[0] = -94.996374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839340763, states[0] = -94.996720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851853518, states[0] = -94.996129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864198789, states[0] = -94.822309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876608606, states[0] = -29.026460, states[40]= 0.000509
Saving checkpoint... 
Iteration: 1888734513, states[0] = -94.880967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901229152, states[0] = -94.871007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913504220, states[0] = 30.543618, states[40]= 0.158307
Saving checkpoint... 
Iteration: 1926168168, states[0] = -94.374872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938510130, states[0] = 22.801284, states[40]= 0.051218
Saving checkpoint... 
Iteration: 1950772281, states[0] = -94.924289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963444227, states[0] = -95.009680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975750545, states[0] = -94.898673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988348579, states[0] = -94.978837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000618318, states[0] = -38.008488, states[40]= 0.000171
Saving checkpoint... 
Iteration: 2013187194, states[0] = -94.786215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025719334, states[0] = -94.851002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038418741, states[0] = -95.003463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050753591, states[0] = -94.902157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063460241, states[0] = -95.012040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075833594, states[0] = -94.970719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088666821, states[0] = -94.155216, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.893515
 - CaMKt in component CaMK (millimolar): 0.007013
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.568448
 - nass in component intracellular_ions (millimolar): 6.568508
 - ki in component intracellular_ions (millimolar): 145.408140
 - kss in component intracellular_ions (millimolar): 145.408120
 - cansr in component intracellular_ions (millimolar): 1.315463
 - cajsr in component intracellular_ions (millimolar): 1.277535
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003622
 - hf in component INa (dimensionless): 0.879856
 - hs in component INa (dimensionless): 0.879851
 - j in component INa (dimensionless): 0.879822
 - hsp in component INa (dimensionless): 0.725557
 - jp in component INa (dimensionless): 0.879803
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709994
 - hLp in component INaL (dimensionless): 0.452652
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622488
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.697680
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936508
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001616
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328034
 - xs1 in component IKs (dimensionless): 0.239197
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997339
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:58:33 (17816): called boinc_finish(0)

</stderr_txt>
]]>


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