𝕏

Task 55839065

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_234_2
Workunit 26494459
Created 3 Jul 2024, 3:28:52 UTC
Sent 3 Jul 2024, 6:14:25 UTC
Report deadline 6 Jul 2024, 15:50:25 UTC
Received 3 Jul 2024, 11:12:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218045
Run time 1 hours 31 min 34 sec
CPU time 1 hours 29 min 47 sec
Validate state Valid
Credit 63.60
Device peak FLOPS 4.97 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.94 MB
Peak swap size 6.23 MB
Peak disk usage 0.25 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_234.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_234_2_r1249825128_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_234_2_r1249825128_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.701878
     * GNaL_b in INaL: 0.005458
     * Gto_b in Ito: 0.085059
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031655
     * GKs_b in IKs: 0.001952
     * GK1_b in IK1: 0.167264
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.903653
     * GKb_b in IKb: 0.003781
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031651
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17559754, states[0] = 6.025328, states[40]= 0.004792
Saving checkpoint... 
Iteration: 43095798, states[0] = -17.966710, states[40]= 0.001135
Saving checkpoint... 
Iteration: 68604871, states[0] = -25.777344, states[40]= 0.000666
Saving checkpoint... 
Iteration: 94140782, states[0] = -62.447031, states[40]= 0.000003
Saving checkpoint... 
Iteration: 119667063, states[0] = -94.266975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145200359, states[0] = -94.833996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162838440, states[0] = -94.987195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188390365, states[0] = -95.007993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213955410, states[0] = -95.023234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239495511, states[0] = -95.028904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265032853, states[0] = 17.537494, states[40]= 0.005748
Saving checkpoint... 
Iteration: 286373816, states[0] = -95.001912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311635383, states[0] = -55.753741, states[40]= 0.000011
Saving checkpoint... 
Iteration: 337156288, states[0] = -85.240617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357506393, states[0] = 25.594380, states[40]= 0.119906
Saving checkpoint... 
Iteration: 382839042, states[0] = -94.986584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408374633, states[0] = -95.002114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433921055, states[0] = -95.015918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459454386, states[0] = -95.022723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485005446, states[0] = 27.259904, states[40]= 0.140967
Saving checkpoint... 
Iteration: 510546563, states[0] = 12.624253, states[40]= 0.005047
Saving checkpoint... 
Iteration: 536119449, states[0] = -39.015557, states[40]= 0.000149
Saving checkpoint... 
Iteration: 561682290, states[0] = -94.791002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587253757, states[0] = -94.917273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612819434, states[0] = -94.975296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638368115, states[0] = -94.999496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663535795, states[0] = 16.557375, states[40]= 0.005500
Saving checkpoint... 
Iteration: 678796114, states[0] = -94.958877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687985267, states[0] = -95.027257, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_234.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_234_2_r1249825128_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_234_2_r1249825128_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.701878
     * GNaL_b in INaL: 0.005458
     * Gto_b in Ito: 0.085059
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031655
     * GKs_b in IKs: 0.001952
     * GK1_b in IK1: 0.167264
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.903653
     * GKb_b in IKb: 0.003781
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031651
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 687985267
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.027257 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 712172250, states[0] = -94.671411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727711841, states[0] = -94.854134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750825291, states[0] = -94.978759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774723324, states[0] = -94.873972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798506666, states[0] = 25.233260, states[40]= 0.113580
Saving checkpoint... 
Iteration: 820065955, states[0] = 4.518470, states[40]= 0.004699
Saving checkpoint... 
Iteration: 835911730, states[0] = -95.013340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859770347, states[0] = -94.935587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880447024, states[0] = -95.021120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887309100, states[0] = -94.968327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903929787, states[0] = -95.017610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928731801, states[0] = -94.887238, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_234.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_234_2_r1249825128_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_234_2_r1249825128_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.701878
     * GNaL_b in INaL: 0.005458
     * Gto_b in Ito: 0.085059
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031655
     * GKs_b in IKs: 0.001952
     * GK1_b in IK1: 0.167264
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.903653
     * GKb_b in IKb: 0.003781
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031651
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 928731801
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.887238 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 944837248, states[0] = -94.985285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953018396, states[0] = 21.318371, states[40]= 0.011406
Saving checkpoint... 
Iteration: 961799723, states[0] = -94.961484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986825787, states[0] = -94.978898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011973402, states[0] = -95.025407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037452070, states[0] = -95.021941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062973869, states[0] = -95.025443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088457298, states[0] = -95.022818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113834124, states[0] = -94.983512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137775083, states[0] = -94.940134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162645365, states[0] = -67.672274, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1180300150, states[0] = -94.961665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197917213, states[0] = -95.014493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223344362, states[0] = -94.988711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241039764, states[0] = 15.160001, states[40]= 0.005268
Saving checkpoint... 
Iteration: 1266580388, states[0] = -3.503408, states[40]= 0.003699
Saving checkpoint... 
Iteration: 1292114686, states[0] = -34.374241, states[40]= 0.000281
Saving checkpoint... 
Iteration: 1317623476, states[0] = -43.056555, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1343111030, states[0] = -30.869956, states[40]= 0.000425
Saving checkpoint... 
Iteration: 1368624178, states[0] = -43.774948, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1394120093, states[0] = -39.652756, states[40]= 0.000136
Saving checkpoint... 
Iteration: 1419606625, states[0] = -26.678705, states[40]= 0.000625
Saving checkpoint... 
Iteration: 1445057079, states[0] = 8.434080, states[40]= 0.004885
Saving checkpoint... 
Iteration: 1470493681, states[0] = -95.027807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495998395, states[0] = -95.028347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521343932, states[0] = 10.959869, states[40]= 0.005847
Saving checkpoint... 
Iteration: 1546600190, states[0] = -38.172423, states[40]= 0.000169
Saving checkpoint... 
Iteration: 1571872069, states[0] = -95.122249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1597161301, states[0] = -95.267628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622455634, states[0] = 3.953314, states[40]= 0.005288
Saving checkpoint... 
Iteration: 1647751696, states[0] = -95.035717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665230419, states[0] = -95.236163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690531151, states[0] = 16.429916, states[40]= 0.006915
Saving checkpoint... 
Iteration: 1715858605, states[0] = -95.090743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741083501, states[0] = -95.155900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1766419574, states[0] = 20.773455, states[40]= 0.011480
Saving checkpoint... 
Iteration: 1783953184, states[0] = -95.056031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1809217149, states[0] = -94.907027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834481021, states[0] = -95.050160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856301772, states[0] = -94.975249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881535353, states[0] = 16.624674, states[40]= 0.005530
Saving checkpoint... 
Iteration: 1906858608, states[0] = -94.997609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932135605, states[0] = -56.108723, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1957345282, states[0] = -94.989282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982664604, states[0] = -93.617326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007947855, states[0] = -95.020638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033313865, states[0] = -94.970816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058642086, states[0] = -63.495774, states[40]= 0.000003
Saving checkpoint... 
Iteration: 2083967622, states[0] = -95.023806, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.903970
 - CaMKt in component CaMK (millimolar): 0.006996
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.600198
 - nass in component intracellular_ions (millimolar): 6.600258
 - ki in component intracellular_ions (millimolar): 145.376620
 - kss in component intracellular_ions (millimolar): 145.376601
 - cansr in component intracellular_ions (millimolar): 1.315028
 - cajsr in component intracellular_ions (millimolar): 1.277153
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003618
 - hf in component INa (dimensionless): 0.880038
 - hs in component INa (dimensionless): 0.880033
 - j in component INa (dimensionless): 0.880005
 - hsp in component INa (dimensionless): 0.725900
 - jp in component INa (dimensionless): 0.879986
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710255
 - hLp in component INaL (dimensionless): 0.452918
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622417
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697616
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936501
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001616
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329480
 - xs1 in component IKs (dimensionless): 0.239085
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:11:42 (6936): called boinc_finish(0)

</stderr_txt>
]]>