𝕏

Task 55838305

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_76_2
Workunit 26251767
Created 2 Jul 2024, 23:34:41 UTC
Sent 3 Jul 2024, 6:08:33 UTC
Report deadline 6 Jul 2024, 15:44:33 UTC
Received 3 Jul 2024, 18:56:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235804
Run time 1 hours 11 min 45 sec
CPU time 1 hours 9 min 56 sec
Validate state Valid
Credit 60.81
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.22 MB
Peak swap size 5.27 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_76.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_76_2_r703575060_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Pueyo_APDR-conf_76_2_r703575060_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.549654
     * GNaL_b in INaL: 0.006926
     * Gto_b in Ito: 0.084512
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030829
     * GKs_b in IKs: 0.001874
     * GK1_b in IK1: 0.174811
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 65.843664
     * GKb_b in IKb: 0.003845
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022976
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13657707, states[0] = -80.220816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34055459, states[0] = 10.322828, states[40]= 0.004899
Saving checkpoint... 
Iteration: 41930975, states[0] = -95.028020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55512107, states[0] = 22.854759, states[40]= 0.031590
Saving checkpoint... 
Iteration: 62925941, states[0] = -95.019632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84480993, states[0] = -95.025999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104299842, states[0] = -94.956819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118466763, states[0] = -95.021135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138737682, states[0] = -94.887313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158655989, states[0] = -71.935573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 178707852, states[0] = -94.836310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198847687, states[0] = -94.984433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218793297, states[0] = -94.949088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238612973, states[0] = -26.456349, states[40]= 0.000709
Saving checkpoint... 
Iteration: 258817153, states[0] = -94.966800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278929829, states[0] = -95.012324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299240173, states[0] = -94.889920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319210492, states[0] = -94.840899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339369346, states[0] = -94.993795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359161356, states[0] = -81.050874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379330076, states[0] = -94.974713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399289243, states[0] = -94.945398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419222069, states[0] = -94.861469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438968556, states[0] = -95.019599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458904248, states[0] = -95.005608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475689845, states[0] = -94.797466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495637215, states[0] = -49.283854, states[40]= 0.000036
Saving checkpoint... 
Iteration: 515605254, states[0] = -19.659415, states[40]= 0.001030
Saving checkpoint... 
Iteration: 535395713, states[0] = -95.002990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555420104, states[0] = -95.009792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575486989, states[0] = -95.022191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590994469, states[0] = -95.023145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610735705, states[0] = -94.883131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630751848, states[0] = -94.905489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650691866, states[0] = -94.802745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670523367, states[0] = 21.097485, states[40]= 0.007288
Saving checkpoint... 
Iteration: 690665583, states[0] = -88.387538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710962802, states[0] = -95.018463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730901330, states[0] = -95.004558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750427382, states[0] = -95.011404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770384224, states[0] = -94.999033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790248698, states[0] = -94.901285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803917901, states[0] = -95.009058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823555515, states[0] = 10.692715, states[40]= 0.004896
Saving checkpoint... 
Iteration: 837773293, states[0] = -94.929955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857526446, states[0] = 20.379369, states[40]= 0.006420
Saving checkpoint... 
Iteration: 871542083, states[0] = 15.595363, states[40]= 0.005068
Saving checkpoint... 
Iteration: 890609036, states[0] = -22.988936, states[40]= 0.000864
Saving checkpoint... 
Iteration: 910203275, states[0] = -94.826661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923718960, states[0] = -94.855745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942788224, states[0] = -94.944108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962035913, states[0] = 17.656022, states[40]= 0.005330
Saving checkpoint... 
Iteration: 981244346, states[0] = -94.895281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999987562, states[0] = -95.021960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013725616, states[0] = -94.866971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032665319, states[0] = -87.991899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051488602, states[0] = -95.022060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070866353, states[0] = -94.992049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089859026, states[0] = -94.988913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108547809, states[0] = 13.561753, states[40]= 0.004958
Saving checkpoint... 
Iteration: 1127699597, states[0] = -94.819190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146515254, states[0] = 22.494555, states[40]= 0.016898
Saving checkpoint... 
Iteration: 1165780359, states[0] = -94.936720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185361900, states[0] = -94.990094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204382196, states[0] = -94.998006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224118594, states[0] = -31.436036, states[40]= 0.000452
Saving checkpoint... 
Iteration: 1243186478, states[0] = -94.784521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262473906, states[0] = -95.019833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282304391, states[0] = -94.957034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301320421, states[0] = -94.968144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320565871, states[0] = 6.510751, states[40]= 0.004784
Saving checkpoint... 
Iteration: 1339491169, states[0] = -95.022186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359106871, states[0] = -21.083953, states[40]= 0.000951
Saving checkpoint... 
Iteration: 1378281559, states[0] = -94.937705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397263180, states[0] = -94.918606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416434613, states[0] = -95.012550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435415870, states[0] = -95.008080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454643649, states[0] = -56.234530, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1468216453, states[0] = -94.850927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487126104, states[0] = -38.269295, states[40]= 0.000188
Saving checkpoint... 
Iteration: 1506697899, states[0] = -27.628544, states[40]= 0.000602
Saving checkpoint... 
Iteration: 1525623328, states[0] = -57.038843, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1539045218, states[0] = 11.341266, states[40]= 0.005790
Saving checkpoint... 
Iteration: 1552359738, states[0] = -95.038042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568979144, states[0] = -95.255348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582085589, states[0] = -95.128688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600740407, states[0] = -95.221934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613813109, states[0] = -46.884431, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1632595516, states[0] = -95.273619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652277516, states[0] = -95.114596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671280471, states[0] = -95.263429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690073997, states[0] = -95.106375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709073482, states[0] = -95.257931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727425028, states[0] = 19.667274, states[40]= 0.007903
Saving checkpoint... 
Iteration: 1746225461, states[0] = -95.204835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764970142, states[0] = -3.613449, states[40]= 0.004152
Saving checkpoint... 
Iteration: 1778409743, states[0] = 24.169242, states[40]= 0.055428
Saving checkpoint... 
Iteration: 1796371080, states[0] = -95.255881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814896530, states[0] = -95.039741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827806600, states[0] = -94.985024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841479139, states[0] = -95.038283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859846181, states[0] = -94.992922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872946563, states[0] = -95.021859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891510105, states[0] = 23.318830, states[40]= 0.050566
Saving checkpoint... 
Iteration: 1904946929, states[0] = -95.017513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923558593, states[0] = 9.461201, states[40]= 0.004875
Saving checkpoint... 
Iteration: 1942198008, states[0] = -94.816269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961030783, states[0] = 19.207978, states[40]= 0.005754
Saving checkpoint... 
Iteration: 1979893961, states[0] = -95.001650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998715152, states[0] = -94.848334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017821137, states[0] = -94.968122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037207436, states[0] = -94.833874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056941722, states[0] = -95.013552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070350592, states[0] = -94.984285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089407977, states[0] = -95.005431, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.898543
 - CaMKt in component CaMK (millimolar): 0.007395
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.748163
 - nass in component intracellular_ions (millimolar): 6.748224
 - ki in component intracellular_ions (millimolar): 145.223203
 - kss in component intracellular_ions (millimolar): 145.223184
 - cansr in component intracellular_ions (millimolar): 1.336850
 - cajsr in component intracellular_ions (millimolar): 1.297922
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003620
 - hf in component INa (dimensionless): 0.879943
 - hs in component INa (dimensionless): 0.879939
 - j in component INa (dimensionless): 0.879909
 - hsp in component INa (dimensionless): 0.725722
 - jp in component INa (dimensionless): 0.879889
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708329
 - hLp in component INaL (dimensionless): 0.447562
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.614370
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.688020
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930441
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999867
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001703
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337160
 - xs1 in component IKs (dimensionless): 0.251976
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:33:51 (35412): called boinc_finish(0)

</stderr_txt>
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