𝕏

Task 55837828

Name HuVeMOp_20240629201600757918_ORdGradInc_k_25-BASE_MID-conf_759_2
Workunit 26276323
Created 2 Jul 2024, 21:24:49 UTC
Sent 3 Jul 2024, 6:10:50 UTC
Report deadline 6 Jul 2024, 6:10:50 UTC
Received 4 Jul 2024, 17:12:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 72956
Run time 1 hours 37 min 26 sec
CPU time 1 hours 18 min 16 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.95 MB
Peak swap size 4.13 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-BASE_MID-conf_759.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-BASE_MID-conf_759_2_r803616163_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-BASE_MID-conf_759_2_r803616163_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 95.660445
     * GNaL_b in INaL: 0.005206
     * Gto_b in Ito: 0.072969
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029862
     * GKs_b in IKs: 0.001805
     * GK1_b in IK1: 0.171760
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 70.879840
     * GKb_b in IKb: 0.003822
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023715
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10240572, states[0] = -86.406952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20718904, states[0] = -84.350444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29913618, states[0] = -86.880885, states[40]= 0.000002
Saving checkpoint... 
Iteration: 41120827, states[0] = -1.202265, states[40]= 0.000108
Saving checkpoint... 
Iteration: 52533267, states[0] = 32.323977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63351970, states[0] = -86.849435, states[40]= 0.000002
Saving checkpoint... 
Iteration: 72978729, states[0] = -86.967389, states[40]= 0.000002
Saving checkpoint... 
Iteration: 83929065, states[0] = -86.947059, states[40]= 0.000002
Saving checkpoint... 
Iteration: 94804268, states[0] = -86.762794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 104240262, states[0] = -86.488372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114382763, states[0] = -86.914486, states[40]= 0.000002
Saving checkpoint... 
Iteration: 124960570, states[0] = -86.975761, states[40]= 0.000002
Saving checkpoint... 
Iteration: 134961795, states[0] = -86.977213, states[40]= 0.000002
Saving checkpoint... 
Iteration: 143506208, states[0] = 24.713391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154958309, states[0] = -86.976261, states[40]= 0.000002
Saving checkpoint... 
Iteration: 165569079, states[0] = 20.495005, states[40]= 0.000001
Saving checkpoint... 
Iteration: 175608269, states[0] = 2.596012, states[40]= 0.000074
Saving checkpoint... 
Iteration: 187052540, states[0] = 26.641791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197679566, states[0] = -53.357871, states[40]= 0.000081
Saving checkpoint... 
Iteration: 207592690, states[0] = 10.189571, states[40]= 0.000017
Saving checkpoint... 
Iteration: 216996003, states[0] = -86.989979, states[40]= 0.000002
Saving checkpoint... 
Iteration: 226095357, states[0] = 8.937683, states[40]= 0.000023
Saving checkpoint... 
Iteration: 235983407, states[0] = -86.984740, states[40]= 0.000002
Saving checkpoint... 
Iteration: 245230252, states[0] = -86.425680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254107313, states[0] = 3.052803, states[40]= 0.000069
Saving checkpoint... 
Iteration: 263591953, states[0] = 10.521481, states[40]= 0.000016
Saving checkpoint... 
Iteration: 273187779, states[0] = -63.134374, states[40]= 0.000022
Saving checkpoint... 
Iteration: 284127843, states[0] = -10.002513, states[40]= 0.000193
Saving checkpoint... 
Iteration: 292134428, states[0] = -15.286448, states[40]= 0.000204
Saving checkpoint... 
Iteration: 300402611, states[0] = -86.932373, states[40]= 0.000002
Saving checkpoint... 
Iteration: 309555720, states[0] = 25.537220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317846668, states[0] = -86.859722, states[40]= 0.000002
Saving checkpoint... 
Iteration: 325857021, states[0] = -86.876205, states[40]= 0.000002
Saving checkpoint... 
Iteration: 334236124, states[0] = -86.460222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342293906, states[0] = -86.731465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 350233695, states[0] = -86.443336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358060811, states[0] = 23.687793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367810789, states[0] = -86.779617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376974386, states[0] = -86.973694, states[40]= 0.000002
Saving checkpoint... 
Iteration: 386714628, states[0] = -86.271183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396655198, states[0] = -31.068982, states[40]= 0.000626
Saving checkpoint... 
Iteration: 405770848, states[0] = -86.641490, states[40]= 0.000001
Saving checkpoint... 
Iteration: 415208760, states[0] = -86.002034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424836975, states[0] = -86.836032, states[40]= 0.000002
Saving checkpoint... 
Iteration: 434607084, states[0] = 3.174519, states[40]= 0.000068
Saving checkpoint... 
Iteration: 443284856, states[0] = -86.694781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 452609849, states[0] = 1.717610, states[40]= 0.000085
Saving checkpoint... 
Iteration: 461791439, states[0] = -86.716685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470596142, states[0] = 8.566477, states[40]= 0.000025
Saving checkpoint... 
Iteration: 480255911, states[0] = -86.566838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 488965588, states[0] = -86.963762, states[40]= 0.000002
Saving checkpoint... 
Iteration: 497467277, states[0] = -86.964063, states[40]= 0.000002
Saving checkpoint... 
Iteration: 506203072, states[0] = -84.436884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514987763, states[0] = -86.971283, states[40]= 0.000002
Saving checkpoint... 
Iteration: 523253816, states[0] = -86.553510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 532591032, states[0] = 10.951558, states[40]= 0.000014
Saving checkpoint... 
Iteration: 540327567, states[0] = -86.810348, states[40]= 0.000002
Saving checkpoint... 
Iteration: 548758694, states[0] = -86.577136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 557112080, states[0] = 0.502933, states[40]= 0.000100
Saving checkpoint... 
Iteration: 566567918, states[0] = 20.938261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574847468, states[0] = -86.846949, states[40]= 0.000002
Saving checkpoint... 
Iteration: 583989115, states[0] = -86.967980, states[40]= 0.000002
Saving checkpoint... 
Iteration: 592683963, states[0] = -58.306156, states[40]= 0.000042
Saving checkpoint... 
Iteration: 600588531, states[0] = 12.096464, states[40]= 0.000011
Saving checkpoint... 
Iteration: 609322933, states[0] = -86.796220, states[40]= 0.000002
Saving checkpoint... 
Iteration: 617027447, states[0] = 32.576878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626379837, states[0] = -86.890638, states[40]= 0.000002
Saving checkpoint... 
Iteration: 634500186, states[0] = -64.141182, states[40]= 0.000002
Saving checkpoint... 
Iteration: 643136808, states[0] = -17.164374, states[40]= 0.000223
Saving checkpoint... 
Iteration: 651303157, states[0] = -86.742750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 661305252, states[0] = -86.748210, states[40]= 0.000001
Saving checkpoint... 
Iteration: 669979456, states[0] = -86.959726, states[40]= 0.000002
Saving checkpoint... 
Iteration: 678710296, states[0] = -86.102348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687906749, states[0] = -86.914873, states[40]= 0.000002
Saving checkpoint... 
Iteration: 696533027, states[0] = 31.821159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704898743, states[0] = -86.906570, states[40]= 0.000002
Saving checkpoint... 
Iteration: 713860274, states[0] = -86.859801, states[40]= 0.000002
Saving checkpoint... 
Iteration: 722504397, states[0] = 20.341034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 729985090, states[0] = -86.958598, states[40]= 0.000002
Saving checkpoint... 
Iteration: 738756997, states[0] = -86.557947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 746793853, states[0] = -86.708851, states[40]= 0.000001
Saving checkpoint... 
Iteration: 755678571, states[0] = -52.316879, states[40]= 0.000092
Saving checkpoint... 
Iteration: 764673456, states[0] = -47.133904, states[40]= 0.000171
Saving checkpoint... 
Iteration: 772998215, states[0] = -86.960694, states[40]= 0.000002
Saving checkpoint... 
Iteration: 780896518, states[0] = -86.900249, states[40]= 0.000002
Saving checkpoint... 
Iteration: 788975399, states[0] = -86.951615, states[40]= 0.000002
Saving checkpoint... 
Iteration: 797602058, states[0] = 5.723986, states[40]= 0.000043
Saving checkpoint... 
Iteration: 806037263, states[0] = 30.983429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815954030, states[0] = -86.940247, states[40]= 0.000002
Saving checkpoint... 
Iteration: 825414545, states[0] = -86.913939, states[40]= 0.000002
Saving checkpoint... 
Iteration: 836116641, states[0] = -2.136291, states[40]= 0.000135
Saving checkpoint... 
Iteration: 845514218, states[0] = 31.425777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855761427, states[0] = -86.573376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864650567, states[0] = -27.463223, states[40]= 0.000611
Saving checkpoint... 
Iteration: 874473889, states[0] = -86.946331, states[40]= 0.000002
Saving checkpoint... 
Iteration: 884106668, states[0] = 3.408113, states[40]= 0.000065
Saving checkpoint... 
Iteration: 893604182, states[0] = 4.671779, states[40]= 0.000052
Saving checkpoint... 
Iteration: 903196123, states[0] = -76.006383, states[40]= 0.000004
Saving checkpoint... 
Iteration: 913266601, states[0] = -86.594384, states[40]= 0.000001
Saving checkpoint... 
Iteration: 923410541, states[0] = -86.905256, states[40]= 0.000002
Saving checkpoint... 
Iteration: 933752313, states[0] = -86.522448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 944139118, states[0] = -18.948967, states[40]= 0.000260
Saving checkpoint... 
Iteration: 953629141, states[0] = -10.972965, states[40]= 0.000193
Saving checkpoint... 
Iteration: 963957776, states[0] = -86.934096, states[40]= 0.000002
Saving checkpoint... 
Iteration: 974853024, states[0] = -86.834232, states[40]= 0.000002
Saving checkpoint... 
Iteration: 984649054, states[0] = -26.326491, states[40]= 0.000578
Saving checkpoint... 
Iteration: 994528822, states[0] = 32.442018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004521997, states[0] = 32.791943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015599649, states[0] = 6.907471, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1026109622, states[0] = 1.865577, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1036438364, states[0] = -86.919296, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1046434394, states[0] = -86.916239, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1057500560, states[0] = 28.271498, states[40]= 0.101496
Saving checkpoint... 
Iteration: 1067500896, states[0] = 35.198279, states[40]= 1.231088
Saving checkpoint... 
Iteration: 1077161809, states[0] = -36.436149, states[40]= 0.000473
Saving checkpoint... 
Iteration: 1087110338, states[0] = 1.483553, states[40]= 0.000087
Saving checkpoint... 
Iteration: 1097208998, states[0] = -85.973813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107524452, states[0] = 32.782057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118100567, states[0] = 6.465706, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1126766431, states[0] = -86.581702, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136787446, states[0] = -86.665509, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146913622, states[0] = -86.895594, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1157437041, states[0] = -86.911864, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1168161895, states[0] = -36.500109, states[40]= 0.000470
Saving checkpoint... 
Iteration: 1178412704, states[0] = -86.893140, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1188192545, states[0] = -69.945486, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1198774169, states[0] = -86.611310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1209142374, states[0] = -21.397541, states[40]= 0.000347
Saving checkpoint... 
Iteration: 1219231198, states[0] = -86.377344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229272839, states[0] = -86.604049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1238959051, states[0] = -86.919719, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1249270755, states[0] = -86.594041, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260675089, states[0] = -48.685292, states[40]= 0.000142
Saving checkpoint... 
Iteration: 1271453670, states[0] = -86.915213, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1282099669, states[0] = 6.907013, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1292797597, states[0] = -86.690521, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1303031416, states[0] = 32.099321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313567943, states[0] = 20.945503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1323689460, states[0] = -65.239704, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1336628043, states[0] = -10.074040, states[40]= 0.000191
Saving checkpoint... 
Iteration: 1346185204, states[0] = -59.657504, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1357287726, states[0] = -86.654262, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368387658, states[0] = -86.858885, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1379862275, states[0] = -86.826169, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1389823056, states[0] = -86.753457, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1400098375, states[0] = 7.533938, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1409529428, states[0] = 32.378768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419311683, states[0] = -86.723869, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429408149, states[0] = -86.875553, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1438639579, states[0] = -19.261080, states[40]= 0.000267
Saving checkpoint... 
Iteration: 1449569895, states[0] = 20.162063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459970600, states[0] = -86.913005, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1470814684, states[0] = -86.728765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1482081156, states[0] = 15.409305, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1493066770, states[0] = 21.416419, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.797522
 - CaMKt in component CaMK (millimolar): 0.024798
 - cass in component intracellular_ions (millimolar): 0.000092
 - nai in component intracellular_ions (millimolar): 7.963930
 - nass in component intracellular_ions (millimolar): 7.964078
 - ki in component intracellular_ions (millimolar): 143.442056
 - kss in component intracellular_ions (millimolar): 143.442021
 - cansr in component intracellular_ions (millimolar): 2.025149
 - cajsr in component intracellular_ions (millimolar): 1.957881
 - cai in component intracellular_ions (millimolar): 0.000095
 - m in component INa (dimensionless): 0.008187
 - hf in component INa (dimensionless): 0.659440
 - hs in component INa (dimensionless): 0.659411
 - j in component INa (dimensionless): 0.659241
 - hsp in component INa (dimensionless): 0.411357
 - jp in component INa (dimensionless): 0.659119
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.454487
 - hLp in component INaL (dimensionless): 0.219663
 - a in component Ito (dimensionless): 0.001077
 - iF in component Ito (dimensionless): 0.999461
 - iS in component Ito (dimensionless): 0.527312
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999461
 - iSp in component Ito (dimensionless): 0.570218
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.871711
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999558
 - jca in component ICaL (dimensionless): 0.999932
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003768
 - xrf in component IKr (dimensionless): 0.000011
 - xrs in component IKr (dimensionless): 0.516543
 - xs1 in component IKs (dimensionless): 0.341609
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997032
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
19:12:15 (8737): called boinc_finish(0)

</stderr_txt>
]]>


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