𝕏

Task 55837827

Name HuVeMOp_20240629201600757918_ORdGradInc_k_25-Drouin_EPI_3000-conf_658_2
Workunit 26276301
Created 2 Jul 2024, 21:24:49 UTC
Sent 3 Jul 2024, 6:10:50 UTC
Report deadline 6 Jul 2024, 6:10:50 UTC
Received 4 Jul 2024, 17:13:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 72956
Run time 1 hours 39 min 22 sec
CPU time 1 hours 19 min 13 sec
Validate state Valid
Credit 44.66
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.69 MB
Peak swap size 4.13 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Drouin_EPI_3000-conf_658.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Drouin_EPI_3000-conf_658_2_r1665992213_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Drouin_EPI_3000-conf_658_2_r1665992213_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.773750
     * GNaL_b in INaL: 0.004779
     * Gto_b in Ito: 0.074576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032065
     * GKs_b in IKs: 0.001755
     * GK1_b in IK1: 0.158863
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 68.869989
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018272
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8338269, states[0] = -94.305656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18646473, states[0] = -94.248498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28859345, states[0] = -94.116973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39431833, states[0] = -94.177317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49786729, states[0] = -93.950763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59589559, states[0] = -94.208449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69253288, states[0] = -93.821000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80252720, states[0] = -94.233280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90428597, states[0] = -94.191822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101291240, states[0] = -94.238189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112421335, states[0] = -94.212490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122856094, states[0] = -94.216363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133484037, states[0] = -94.213408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143170224, states[0] = -94.247700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152751004, states[0] = -94.222975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162983959, states[0] = -94.235612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173089603, states[0] = -94.246699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182647026, states[0] = -94.228269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193872027, states[0] = -94.152440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205595565, states[0] = 4.788927, states[40]= 0.000071
Saving checkpoint... 
Iteration: 215848436, states[0] = -94.220350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225921693, states[0] = -94.239356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235472836, states[0] = -94.216091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245190588, states[0] = -94.248900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255137165, states[0] = -35.213056, states[40]= 0.000278
Saving checkpoint... 
Iteration: 264302089, states[0] = -94.022081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274111758, states[0] = -94.229407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283217439, states[0] = -94.224673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292410472, states[0] = -94.217386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301481385, states[0] = -94.214996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311356834, states[0] = -94.241638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317895614, states[0] = -94.217509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327184920, states[0] = -92.347991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335789962, states[0] = -94.221025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344503289, states[0] = -94.233616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353193399, states[0] = -94.247343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360572320, states[0] = -94.243678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368191380, states[0] = -94.247143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376542060, states[0] = 25.994103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385781471, states[0] = -93.956180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396120424, states[0] = -16.888110, states[40]= 0.000193
Saving checkpoint... 
Iteration: 405110336, states[0] = -6.382249, states[40]= 0.000206
Saving checkpoint... 
Iteration: 414105487, states[0] = -2.179144, states[40]= 0.000166
Saving checkpoint... 
Iteration: 423769544, states[0] = -94.243963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432658354, states[0] = -94.246343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441196771, states[0] = -93.432794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450611828, states[0] = -94.245010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458898729, states[0] = -94.215214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467925555, states[0] = -94.214185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476170263, states[0] = -94.245662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485297981, states[0] = -94.241779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494536450, states[0] = -94.229625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503297054, states[0] = -94.241539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512248067, states[0] = -94.243396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521131719, states[0] = -94.244590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529676138, states[0] = -84.081454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 538077270, states[0] = -94.226970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547372065, states[0] = -94.214741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556017757, states[0] = -94.229592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564451854, states[0] = -94.210288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572036325, states[0] = -94.235681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580670007, states[0] = -74.264110, states[40]= 0.000003
Saving checkpoint... 
Iteration: 590049559, states[0] = -94.237426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598255483, states[0] = -94.218265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606940065, states[0] = -94.232756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615107471, states[0] = -3.815776, states[40]= 0.000186
Saving checkpoint... 
Iteration: 623150033, states[0] = -94.243311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631973125, states[0] = -94.218294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641237639, states[0] = -94.241736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649765589, states[0] = -93.890346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658171834, states[0] = -94.220789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665953935, states[0] = -94.210171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674641948, states[0] = -94.221845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683523317, states[0] = -94.227316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693201586, states[0] = -93.486025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701238646, states[0] = -94.240764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708963501, states[0] = -94.229946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717355620, states[0] = -94.123274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725047938, states[0] = -94.235084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733514422, states[0] = 23.571050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741366262, states[0] = -94.137440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749199782, states[0] = -94.241047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757334213, states[0] = -94.212790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765970354, states[0] = -94.228705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775100123, states[0] = -94.222184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783272434, states[0] = -93.916257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790895176, states[0] = -94.168270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799287015, states[0] = -94.213892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807607427, states[0] = -94.239229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815950609, states[0] = -94.207930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824746234, states[0] = -94.215087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833842263, states[0] = -94.211305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843731900, states[0] = -94.238758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852036361, states[0] = 26.542840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861180297, states[0] = -89.526054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871091051, states[0] = -94.221106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880032661, states[0] = -94.223781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888968525, states[0] = -94.226875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898816147, states[0] = -94.047527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907843517, states[0] = -94.101398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916605209, states[0] = -1.950357, states[40]= 0.000163
Saving checkpoint... 
Iteration: 927123026, states[0] = -19.723204, states[40]= 0.000205
Saving checkpoint... 
Iteration: 935851608, states[0] = -94.209371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946671197, states[0] = -76.055205, states[40]= 0.000002
Saving checkpoint... 
Iteration: 956094419, states[0] = -94.236164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964481203, states[0] = -94.204649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974584878, states[0] = -94.219780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984090568, states[0] = 7.764758, states[40]= 0.000041
Saving checkpoint... 
Iteration: 993215458, states[0] = -93.594005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003109210, states[0] = -94.218196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011683540, states[0] = -94.237197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021428066, states[0] = -94.205433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032017926, states[0] = 24.717910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040869350, states[0] = -94.207103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050994715, states[0] = -94.223003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060982023, states[0] = -94.214747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070771016, states[0] = -94.210252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080682587, states[0] = -94.236125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090370246, states[0] = -94.206294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100503556, states[0] = -94.221781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110580152, states[0] = -94.232675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121715910, states[0] = -94.211664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132940111, states[0] = -94.195327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142979522, states[0] = -94.201900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153153278, states[0] = -94.213852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163690749, states[0] = -94.212063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172754711, states[0] = -94.209296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182801517, states[0] = -94.230716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192481166, states[0] = -94.201076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202320670, states[0] = -94.229517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212461926, states[0] = -94.204723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223756357, states[0] = -94.208436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233261986, states[0] = -93.865289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245351448, states[0] = -94.108759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256404263, states[0] = -94.224455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265635940, states[0] = -94.212866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276223654, states[0] = -94.208928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286683117, states[0] = -94.210464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297787158, states[0] = -93.961006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308638015, states[0] = -94.232425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320029450, states[0] = 26.556964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328928471, states[0] = -94.200599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339422207, states[0] = -94.200639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350559336, states[0] = -94.226803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361256526, states[0] = -94.229820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370898268, states[0] = -94.200945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380590882, states[0] = -94.229293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391308452, states[0] = -94.227139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401516528, states[0] = -94.218901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410829726, states[0] = -94.225820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421056056, states[0] = -94.225299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431351202, states[0] = -94.105455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441329291, states[0] = -94.202257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450002274, states[0] = -94.216379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459807796, states[0] = -94.018350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471608400, states[0] = -4.606605, states[40]= 0.000193
Saving checkpoint... 
Iteration: 1480851512, states[0] = -94.105146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490363944, states[0] = -94.222866, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.071641
 - CaMKt in component CaMK (millimolar): 0.003609
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 7.284808
 - nass in component intracellular_ions (millimolar): 7.284946
 - ki in component intracellular_ions (millimolar): 144.359911
 - kss in component intracellular_ions (millimolar): 144.359894
 - cansr in component intracellular_ions (millimolar): 2.431509
 - cajsr in component intracellular_ions (millimolar): 2.432043
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003935
 - hf in component INa (dimensionless): 0.864831
 - hs in component INa (dimensionless): 0.864833
 - j in component INa (dimensionless): 0.864840
 - hsp in component INa (dimensionless): 0.697899
 - jp in component INa (dimensionless): 0.864844
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706810
 - hLp in component INaL (dimensionless): 0.510288
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999849
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991129
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005058
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.025445
 - xs1 in component IKs (dimensionless): 0.068507
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997547
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:13:01 (8534): called boinc_finish(0)

</stderr_txt>
]]>


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