𝕏

Task 55837259

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-BASE_MID-conf_804_3
Workunit 26239729
Created 2 Jul 2024, 18:26:15 UTC
Sent 3 Jul 2024, 6:04:08 UTC
Report deadline 6 Jul 2024, 6:04:08 UTC
Received 4 Jul 2024, 9:08:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232190
Run time 2 hours 21 min 58 sec
CPU time 2 hours 19 min 24 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.84 MB
Peak swap size 4.08 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-BASE_MID-conf_804.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-BASE_MID-conf_804_3_r512226633_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-BASE_MID-conf_804_3_r512226633_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 97.113180
     * GNaL_b in INaL: 0.005814
     * Gto_b in Ito: 0.091938
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031447
     * GKs_b in IKs: 0.002145
     * GK1_b in IK1: 0.177814
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 70.502812
     * GKb_b in IKb: 0.003720
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022149
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11005440, states[0] = 20.898953, states[40]= 0.379050
Saving checkpoint... 
Iteration: 22038514, states[0] = 31.255248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33105324, states[0] = 6.178869, states[40]= 0.000044
Saving checkpoint... 
Iteration: 44153444, states[0] = -27.646879, states[40]= 0.000732
Saving checkpoint... 
Iteration: 55192984, states[0] = -72.467734, states[40]= 0.000007
Saving checkpoint... 
Iteration: 66268529, states[0] = -86.629234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 77285140, states[0] = -86.704845, states[40]= 0.000001
Saving checkpoint... 
Iteration: 88279425, states[0] = -86.689821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 99317422, states[0] = -86.811723, states[40]= 0.000002
Saving checkpoint... 
Iteration: 110322748, states[0] = -86.827209, states[40]= 0.000002
Saving checkpoint... 
Iteration: 121313088, states[0] = -86.805774, states[40]= 0.000002
Saving checkpoint... 
Iteration: 132356077, states[0] = -86.892980, states[40]= 0.000002
Saving checkpoint... 
Iteration: 143365594, states[0] = -86.907446, states[40]= 0.000002
Saving checkpoint... 
Iteration: 154387403, states[0] = -86.934252, states[40]= 0.000002
Saving checkpoint... 
Iteration: 165417637, states[0] = -86.961679, states[40]= 0.000002
Saving checkpoint... 
Iteration: 176464276, states[0] = -86.989022, states[40]= 0.000002
Saving checkpoint... 
Iteration: 187467747, states[0] = -86.990152, states[40]= 0.000002
Saving checkpoint... 
Iteration: 198518189, states[0] = 30.572822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209553776, states[0] = 25.568322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220585740, states[0] = 12.705771, states[40]= 0.000016
Saving checkpoint... 
Iteration: 231614765, states[0] = -2.893780, states[40]= 0.000214
Saving checkpoint... 
Iteration: 242647044, states[0] = -28.619255, states[40]= 0.000814
Saving checkpoint... 
Iteration: 253677877, states[0] = -59.090010, states[40]= 0.000053
Saving checkpoint... 
Iteration: 264745585, states[0] = -86.534023, states[40]= 0.000001
Saving checkpoint... 
Iteration: 275761336, states[0] = -86.617322, states[40]= 0.000001
Saving checkpoint... 
Iteration: 286809774, states[0] = -86.792604, states[40]= 0.000002
Saving checkpoint... 
Iteration: 297844430, states[0] = -86.867311, states[40]= 0.000002
Saving checkpoint... 
Iteration: 308865969, states[0] = -86.900105, states[40]= 0.000002
Saving checkpoint... 
Iteration: 319903473, states[0] = -86.941199, states[40]= 0.000002
Saving checkpoint... 
Iteration: 330910164, states[0] = -86.946216, states[40]= 0.000002
Saving checkpoint... 
Iteration: 341954188, states[0] = -86.974235, states[40]= 0.000002
Saving checkpoint... 
Iteration: 352997154, states[0] = -86.990501, states[40]= 0.000002
Saving checkpoint... 
Iteration: 364038052, states[0] = 29.778204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375056593, states[0] = 24.622217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386110608, states[0] = -0.227867, states[40]= 0.000166
Saving checkpoint... 
Iteration: 397156786, states[0] = -36.927632, states[40]= 0.000614
Saving checkpoint... 
Iteration: 408191446, states[0] = -80.088627, states[40]= 0.000003
Saving checkpoint... 
Iteration: 419224452, states[0] = -86.382028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 430280014, states[0] = -86.687245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 441329904, states[0] = -86.829606, states[40]= 0.000002
Saving checkpoint... 
Iteration: 452359477, states[0] = -86.881071, states[40]= 0.000002
Saving checkpoint... 
Iteration: 463420399, states[0] = -86.945230, states[40]= 0.000002
Saving checkpoint... 
Iteration: 474448797, states[0] = -86.962444, states[40]= 0.000002
Saving checkpoint... 
Iteration: 485493699, states[0] = -86.980452, states[40]= 0.000002
Saving checkpoint... 
Iteration: 496518605, states[0] = 30.659862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507527498, states[0] = 31.157747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518571253, states[0] = 19.063690, states[40]= 0.000003
Saving checkpoint... 
Iteration: 529586046, states[0] = 12.565972, states[40]= 0.000017
Saving checkpoint... 
Iteration: 540617637, states[0] = -4.890612, states[40]= 0.000241
Saving checkpoint... 
Iteration: 551657303, states[0] = -37.380226, states[40]= 0.000592
Saving checkpoint... 
Iteration: 562682921, states[0] = -65.955960, states[40]= 0.000021
Saving checkpoint... 
Iteration: 573713576, states[0] = -86.281679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584785887, states[0] = -86.698337, states[40]= 0.000002
Saving checkpoint... 
Iteration: 595863335, states[0] = -86.876899, states[40]= 0.000002
Saving checkpoint... 
Iteration: 606893303, states[0] = -86.912065, states[40]= 0.000002
Saving checkpoint... 
Iteration: 617935977, states[0] = -86.945345, states[40]= 0.000002
Saving checkpoint... 
Iteration: 628951956, states[0] = -86.953659, states[40]= 0.000002
Saving checkpoint... 
Iteration: 639990339, states[0] = -86.968929, states[40]= 0.000002
Saving checkpoint... 
Iteration: 651031103, states[0] = 30.869880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662065825, states[0] = 21.241563, states[40]= 0.000001
Saving checkpoint... 
Iteration: 673097292, states[0] = 7.122814, states[40]= 0.000053
Saving checkpoint... 
Iteration: 684101789, states[0] = 4.789007, states[40]= 0.000081
Saving checkpoint... 
Iteration: 695143039, states[0] = -25.421555, states[40]= 0.000691
Saving checkpoint... 
Iteration: 706178688, states[0] = -60.045888, states[40]= 0.000047
Saving checkpoint... 
Iteration: 717219463, states[0] = -86.322159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728254469, states[0] = -86.551291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 739312684, states[0] = -86.769246, states[40]= 0.000002
Saving checkpoint... 
Iteration: 750351397, states[0] = -86.848272, states[40]= 0.000002
Saving checkpoint... 
Iteration: 761369769, states[0] = -86.874442, states[40]= 0.000002
Saving checkpoint... 
Iteration: 772401308, states[0] = -86.908535, states[40]= 0.000002
Saving checkpoint... 
Iteration: 783427361, states[0] = -86.928528, states[40]= 0.000002
Saving checkpoint... 
Iteration: 794463898, states[0] = -86.948250, states[40]= 0.000002
Saving checkpoint... 
Iteration: 805500526, states[0] = 17.703452, states[40]= 0.046335
Saving checkpoint... 
Iteration: 816535722, states[0] = 30.220835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827602182, states[0] = 4.586163, states[40]= 0.000084
Saving checkpoint... 
Iteration: 838645033, states[0] = -26.971082, states[40]= 0.000762
Saving checkpoint... 
Iteration: 849662001, states[0] = -41.762213, states[40]= 0.000405
Saving checkpoint... 
Iteration: 860692100, states[0] = -80.853617, states[40]= 0.000002
Saving checkpoint... 
Iteration: 871707820, states[0] = -86.190486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882742219, states[0] = -86.470822, states[40]= 0.000001
Saving checkpoint... 
Iteration: 893766949, states[0] = -86.600815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 904796574, states[0] = -86.712098, states[40]= 0.000002
Saving checkpoint... 
Iteration: 915846240, states[0] = -86.828351, states[40]= 0.000002
Saving checkpoint... 
Iteration: 926896927, states[0] = -86.893939, states[40]= 0.000002
Saving checkpoint... 
Iteration: 937944354, states[0] = -86.928662, states[40]= 0.000002
Saving checkpoint... 
Iteration: 948983105, states[0] = -86.945582, states[40]= 0.000002
Saving checkpoint... 
Iteration: 959981614, states[0] = -86.944290, states[40]= 0.000002
Saving checkpoint... 
Iteration: 971017406, states[0] = 30.409983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982060712, states[0] = 23.179508, states[40]= 0.000001
Saving checkpoint... 
Iteration: 993078026, states[0] = 16.201388, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1004113860, states[0] = -2.250221, states[40]= 0.000201
Saving checkpoint... 
Iteration: 1015135294, states[0] = -19.277799, states[40]= 0.000351
Saving checkpoint... 
Iteration: 1026158530, states[0] = -38.450331, states[40]= 0.000540
Saving checkpoint... 
Iteration: 1037205895, states[0] = -86.137002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048234905, states[0] = -86.412393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1059279025, states[0] = -86.640105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1070335892, states[0] = -86.798809, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1081377153, states[0] = -86.862042, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1092426339, states[0] = -86.906925, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1103471022, states[0] = -86.930468, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1114506666, states[0] = 23.564406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125541460, states[0] = 29.066997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136605578, states[0] = 2.747943, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1147663889, states[0] = -43.576038, states[40]= 0.000337
Saving checkpoint... 
Iteration: 1158720085, states[0] = -86.296188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169746049, states[0] = -86.473818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1180784320, states[0] = -86.651707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1191818043, states[0] = -86.751687, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1202839166, states[0] = -86.796068, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1213894311, states[0] = -86.871935, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1224916577, states[0] = -86.890802, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1235957991, states[0] = -86.915676, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1246992704, states[0] = -86.928745, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1258026293, states[0] = 31.225794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269033237, states[0] = 30.620654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280072865, states[0] = 18.417283, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1291161174, states[0] = -40.906392, states[40]= 0.000435
Saving checkpoint... 
Iteration: 1302195928, states[0] = -84.342870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1313219169, states[0] = -86.277943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324267500, states[0] = -86.573597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1335312183, states[0] = -86.727204, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1346347333, states[0] = -86.800952, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1357351713, states[0] = -86.807504, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1368351045, states[0] = -86.805666, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1379400784, states[0] = -86.866945, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1390392954, states[0] = -86.858606, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1401413225, states[0] = -86.876211, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1412439086, states[0] = -86.893528, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1423467858, states[0] = -86.907532, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1434454072, states[0] = -86.900325, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1445476421, states[0] = -86.909564, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1456490067, states[0] = -86.913783, states[40]= 0.000002


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-BASE_MID-conf_804.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-BASE_MID-conf_804_3_r512226633_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-BASE_MID-conf_804_3_r512226633_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 97.113180
     * GNaL_b in INaL: 0.005814
     * Gto_b in Ito: 0.091938
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031447
     * GKs_b in IKs: 0.002145
     * GK1_b in IK1: 0.177814
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 70.502812
     * GKb_b in IKb: 0.003720
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022149
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1456490067
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.913783 (After loading)
 - states[40]: 0.000002 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1467475896, states[0] = -86.907915, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1478395221, states[0] = -86.854947, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1489341369, states[0] = -86.780669, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.789821
 - CaMKt in component CaMK (millimolar): 0.026314
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 8.139757
 - nass in component intracellular_ions (millimolar): 8.139919
 - ki in component intracellular_ions (millimolar): 143.137644
 - kss in component intracellular_ions (millimolar): 143.137605
 - cansr in component intracellular_ions (millimolar): 2.141978
 - cajsr in component intracellular_ions (millimolar): 2.082852
 - cai in component intracellular_ions (millimolar): 0.000099
 - m in component INa (dimensionless): 0.008193
 - hf in component INa (dimensionless): 0.659156
 - hs in component INa (dimensionless): 0.659128
 - j in component INa (dimensionless): 0.658964
 - hsp in component INa (dimensionless): 0.411055
 - jp in component INa (dimensionless): 0.658846
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.455779
 - hLp in component INaL (dimensionless): 0.222316
 - a in component Ito (dimensionless): 0.001077
 - iF in component Ito (dimensionless): 0.999461
 - iS in component Ito (dimensionless): 0.534115
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999461
 - iSp in component Ito (dimensionless): 0.577936
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.877360
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999618
 - jca in component ICaL (dimensionless): 0.999940
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004254
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.507314
 - xs1 in component IKs (dimensionless): 0.333750
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997034
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
01:07:13 (2026): called boinc_finish(0)

</stderr_txt>
]]>


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