𝕏

Task 55834805

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-BASE_ENDO-conf_894_0
Workunit 26515531
Created 2 Jul 2024, 14:37:30 UTC
Sent 3 Jul 2024, 5:51:14 UTC
Report deadline 6 Jul 2024, 5:51:14 UTC
Received 4 Jul 2024, 22:55:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214494
Run time 2 hours 40 min 53 sec
CPU time 2 hours 17 min 20 sec
Validate state Valid
Credit 44.42
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.60 MB
Peak swap size 6.24 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-BASE_ENDO-conf_894.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-BASE_ENDO-conf_894_0_r939177166_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-BASE_ENDO-conf_894_0_r939177166_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 106.084163
     * GNaL_b in INaL: 0.005472
     * Gto_b in Ito: 0.083347
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032338
     * GKs_b in IKs: 0.001902
     * GK1_b in IK1: 0.165017
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.582964
     * GKb_b in IKb: 0.003815
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031568
     * celltype in environment: 0.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8284174, states[0] = -86.884073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16666554, states[0] = -86.136646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25069946, states[0] = 8.012935, states[40]= 0.003187
Saving checkpoint... 
Iteration: 33377143, states[0] = -86.870047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41563951, states[0] = 11.241868, states[40]= 0.002660
Saving checkpoint... 
Iteration: 50201586, states[0] = -86.480442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58710331, states[0] = -86.512652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67706247, states[0] = -86.491235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76200916, states[0] = -86.465003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84825713, states[0] = -86.788060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93477888, states[0] = -86.882836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101954374, states[0] = -86.874511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110758919, states[0] = -86.661325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119181487, states[0] = -86.351661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127606415, states[0] = -20.667502, states[40]= 0.000992
Saving checkpoint... 
Iteration: 135766660, states[0] = -86.678502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144537026, states[0] = 22.700884, states[40]= 0.001102
Saving checkpoint... 
Iteration: 153211198, states[0] = -86.500122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161904213, states[0] = -86.848492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170279677, states[0] = -86.706037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178282916, states[0] = -86.712422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187617536, states[0] = -32.462493, states[40]= 0.000563
Saving checkpoint... 
Iteration: 195936578, states[0] = -86.863304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204512172, states[0] = 28.413657, states[40]= 0.021628
Saving checkpoint... 
Iteration: 212793769, states[0] = -86.732308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221018810, states[0] = 28.070886, states[40]= 0.002792
Saving checkpoint... 
Iteration: 229351683, states[0] = -86.808586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237828885, states[0] = -86.783849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245931876, states[0] = -86.860924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254032156, states[0] = 24.483292, states[40]= 0.000955
Saving checkpoint... 
Iteration: 262225448, states[0] = -86.553969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271040891, states[0] = 21.229020, states[40]= 0.001264
Saving checkpoint... 
Iteration: 279089851, states[0] = -3.651446, states[40]= 0.003342
Saving checkpoint... 
Iteration: 287384758, states[0] = -86.835127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295285729, states[0] = -86.716937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303310311, states[0] = -86.758522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311728780, states[0] = -86.565629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320007869, states[0] = 28.218473, states[40]= 0.092517
Saving checkpoint... 
Iteration: 328509809, states[0] = 28.253952, states[40]= 0.047911
Saving checkpoint... 
Iteration: 336537884, states[0] = 22.387767, states[40]= 0.001138
Saving checkpoint... 
Iteration: 344378216, states[0] = -86.830231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352786139, states[0] = -86.717449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361296395, states[0] = -86.736037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369258642, states[0] = -86.655947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376059879, states[0] = 13.437018, states[40]= 0.002423
Saving checkpoint... 
Iteration: 382963281, states[0] = -86.871578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389250449, states[0] = -86.633748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397818696, states[0] = -86.769956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406215114, states[0] = -86.513858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414706440, states[0] = -86.477963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423715637, states[0] = -86.515858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432128497, states[0] = -44.060674, states[40]= 0.000146
Saving checkpoint... 
Iteration: 440457188, states[0] = -86.869395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448712324, states[0] = -86.502396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456874149, states[0] = -86.826682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465130144, states[0] = -45.832282, states[40]= 0.000114
Saving checkpoint... 
Iteration: 474263493, states[0] = -86.667664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482744048, states[0] = -86.614655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491187133, states[0] = -86.386993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499537851, states[0] = 22.400609, states[40]= 0.001136
Saving checkpoint... 
Iteration: 507886799, states[0] = -86.835484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516223940, states[0] = -86.547231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524649472, states[0] = -68.266270, states[40]= 0.000003
Saving checkpoint... 
Iteration: 533032455, states[0] = 24.379632, states[40]= 0.000962
Saving checkpoint... 
Iteration: 541533143, states[0] = 24.136743, states[40]= 0.000979
Saving checkpoint... 
Iteration: 549932511, states[0] = -86.859746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558420176, states[0] = -86.854187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566591709, states[0] = -5.250882, states[40]= 0.003116
Saving checkpoint... 
Iteration: 575041601, states[0] = 20.952331, states[40]= 0.001296
Saving checkpoint... 
Iteration: 583896830, states[0] = -86.841518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592322136, states[0] = -86.773641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600687055, states[0] = -86.386034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609067347, states[0] = 10.046691, states[40]= 0.002961
Saving checkpoint... 
Iteration: 618084286, states[0] = 0.550819, states[40]= 0.003662
Saving checkpoint... 
Iteration: 626160954, states[0] = -82.517807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634535518, states[0] = 23.275449, states[40]= 0.001052
Saving checkpoint... 
Iteration: 642442297, states[0] = -86.863235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650716756, states[0] = -86.519226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659027377, states[0] = 26.049563, states[40]= 0.000915
Saving checkpoint... 
Iteration: 667453889, states[0] = -86.867271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676441111, states[0] = -86.862628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684804616, states[0] = -86.748071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693759867, states[0] = -86.657591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702096141, states[0] = -9.498234, states[40]= 0.002368
Saving checkpoint... 
Iteration: 710689448, states[0] = -86.398489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718999269, states[0] = -86.879178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727685079, states[0] = -86.373461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736322025, states[0] = -86.772837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745132090, states[0] = -47.937101, states[40]= 0.000084
Saving checkpoint... 
Iteration: 753781005, states[0] = -86.705476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761556084, states[0] = 15.066505, states[40]= 0.002152
Saving checkpoint... 
Iteration: 770274175, states[0] = -86.691024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778595148, states[0] = -8.497447, states[40]= 0.002553
Saving checkpoint... 
Iteration: 787253671, states[0] = -86.640835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796022810, states[0] = 27.291316, states[40]= 0.001249
Saving checkpoint... 
Iteration: 804451500, states[0] = -86.865833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812727592, states[0] = -86.559089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821445510, states[0] = -86.863622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830275719, states[0] = -86.694092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839650847, states[0] = -70.111888, states[40]= 0.000002
Saving checkpoint... 
Iteration: 848076523, states[0] = 5.334453, states[40]= 0.003512
Saving checkpoint... 
Iteration: 856721567, states[0] = -86.536802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865314020, states[0] = -86.761322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874354260, states[0] = -86.807980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882307209, states[0] = -86.751190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890349054, states[0] = -86.802911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899268102, states[0] = -86.676725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907511619, states[0] = 28.384302, states[40]= 0.026022
Saving checkpoint... 
Iteration: 916293052, states[0] = -86.727641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924384224, states[0] = -86.831841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933008931, states[0] = 28.206522, states[40]= 0.064516
Saving checkpoint... 
Iteration: 941291650, states[0] = -86.725010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949669712, states[0] = -85.876236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958372978, states[0] = -86.823500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967039424, states[0] = 21.799249, states[40]= 0.001200
Saving checkpoint... 
Iteration: 975269508, states[0] = -86.679628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983856827, states[0] = -86.809847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992661559, states[0] = -82.975804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001716791, states[0] = -86.517731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010877439, states[0] = -86.826621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019532182, states[0] = 24.475882, states[40]= 0.000955
Saving checkpoint... 
Iteration: 1028787464, states[0] = -86.716866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037974921, states[0] = -86.871946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046132652, states[0] = -48.545899, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1054924041, states[0] = -86.853734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063139650, states[0] = -56.297816, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1071836540, states[0] = -86.788907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080051797, states[0] = 16.854475, states[40]= 0.001864
Saving checkpoint... 
Iteration: 1088424507, states[0] = -86.853794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097103209, states[0] = -17.075775, states[40]= 0.001245
Saving checkpoint... 
Iteration: 1105678253, states[0] = -86.303611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114196191, states[0] = -86.429227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121976642, states[0] = -86.872025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130130197, states[0] = -45.884045, states[40]= 0.000113
Saving checkpoint... 
Iteration: 1138152625, states[0] = -72.549676, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1146515841, states[0] = 28.395056, states[40]= 0.006575
Saving checkpoint... 
Iteration: 1155518246, states[0] = 28.153335, states[40]= 0.003245
Saving checkpoint... 
Iteration: 1163967472, states[0] = -86.869280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172348636, states[0] = -86.801210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181059458, states[0] = 13.621847, states[40]= 0.002392
Saving checkpoint... 
Iteration: 1190138111, states[0] = -54.563040, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1198615518, states[0] = -30.307737, states[40]= 0.000664
Saving checkpoint... 
Iteration: 1206674405, states[0] = -86.206003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214906281, states[0] = -86.844089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223697115, states[0] = -86.432964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232587449, states[0] = -1.731847, states[40]= 0.003541
Saving checkpoint... 
Iteration: 1240778316, states[0] = -86.697704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249507785, states[0] = 28.225596, states[40]= 0.095185
Saving checkpoint... 
Iteration: 1257892404, states[0] = -86.835714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266105365, states[0] = -19.433297, states[40]= 0.001060
Saving checkpoint... 
Iteration: 1274194690, states[0] = -86.421496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283008604, states[0] = 28.199193, states[40]= 0.072084
Saving checkpoint... 
Iteration: 1290898494, states[0] = -86.839296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299829145, states[0] = -86.779231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308236489, states[0] = -86.587128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317026799, states[0] = 26.223802, states[40]= 0.000926
Saving checkpoint... 
Iteration: 1325586876, states[0] = -1.298892, states[40]= 0.003574
Saving checkpoint... 
Iteration: 1334031698, states[0] = 24.644261, states[40]= 0.000944
Saving checkpoint... 
Iteration: 1342327041, states[0] = -86.776455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350963635, states[0] = -86.867286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359166257, states[0] = -85.223160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368072734, states[0] = 7.375667, states[40]= 0.003312
Saving checkpoint... 
Iteration: 1376792657, states[0] = -86.724823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385279981, states[0] = -86.700485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394146351, states[0] = -64.228683, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1402362418, states[0] = -86.812880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411057743, states[0] = 14.361887, states[40]= 0.002269
Saving checkpoint... 
Iteration: 1419693239, states[0] = -86.413948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428431610, states[0] = -86.855371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436569890, states[0] = 8.815838, states[40]= 0.003133
Saving checkpoint... 
Iteration: 1445051069, states[0] = 17.154285, states[40]= 0.001817
Saving checkpoint... 
Iteration: 1452945089, states[0] = -86.860596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461570691, states[0] = 8.417323, states[40]= 0.003186
Saving checkpoint... 
Iteration: 1470344201, states[0] = -86.795355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479253819, states[0] = -86.638043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487822202, states[0] = -86.769630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496071690, states[0] = 7.912794, states[40]= 0.003249
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.751658
 - CaMKt in component CaMK (millimolar): 0.012032
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.578874
 - nass in component intracellular_ions (millimolar): 6.578966
 - ki in component intracellular_ions (millimolar): 145.308679
 - kss in component intracellular_ions (millimolar): 145.308657
 - cansr in component intracellular_ions (millimolar): 1.616639
 - cajsr in component intracellular_ions (millimolar): 1.573268
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.008224
 - hf in component INa (dimensionless): 0.657746
 - hs in component INa (dimensionless): 0.657726
 - j in component INa (dimensionless): 0.657614
 - hsp in component INa (dimensionless): 0.409568
 - jp in component INa (dimensionless): 0.657536
 - mL in component INaL (dimensionless): 0.000233
 - hL in component INaL (dimensionless): 0.461480
 - hLp in component INaL (dimensionless): 0.235335
 - a in component Ito (dimensionless): 0.001080
 - iF in component Ito (dimensionless): 0.999457
 - iS in component Ito (dimensionless): 0.570901
 - ap in component Ito (dimensionless): 0.000550
 - iFp in component Ito (dimensionless): 0.999457
 - iSp in component Ito (dimensionless): 0.620650
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916969
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999844
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002833
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.458639
 - xs1 in component IKs (dimensionless): 0.267790
 - xs2 in component IKs (dimensionless): 0.000219
 - xk1 in component IK1 (dimensionless): 0.997043
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:54:49 (3096): called boinc_finish(0)

</stderr_txt>
]]>


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