𝕏

Task 55834800

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-BASE_ENDO-conf_594_1
Workunit 26515528
Created 2 Jul 2024, 14:37:30 UTC
Sent 3 Jul 2024, 5:51:14 UTC
Report deadline 6 Jul 2024, 5:51:14 UTC
Received 4 Jul 2024, 22:59:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214494
Run time 2 hours 40 min 55 sec
CPU time 2 hours 17 min 17 sec
Validate state Valid
Credit 43.79
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.21 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-BASE_ENDO-conf_594.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-BASE_ENDO-conf_594_1_r833703114_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-BASE_ENDO-conf_594_1_r833703114_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 103.338723
     * GNaL_b in INaL: 0.005827
     * Gto_b in Ito: 0.086327
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031722
     * GKs_b in IKs: 0.001961
     * GK1_b in IK1: 0.164898
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.570236
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029643
     * celltype in environment: 0.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8567331, states[0] = 8.944133, states[40]= 0.003749
Saving checkpoint... 
Iteration: 17385757, states[0] = -86.896446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25810647, states[0] = -86.791202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34552775, states[0] = 16.434108, states[40]= 0.001651
Saving checkpoint... 
Iteration: 42928417, states[0] = -86.866779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51356449, states[0] = -86.812523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59791480, states[0] = -86.720388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68535254, states[0] = 23.508279, states[40]= 0.000856
Saving checkpoint... 
Iteration: 77114722, states[0] = -27.550891, states[40]= 0.000788
Saving checkpoint... 
Iteration: 85999721, states[0] = -86.869560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94358259, states[0] = -86.799211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102596348, states[0] = -8.134051, states[40]= 0.002550
Saving checkpoint... 
Iteration: 110785885, states[0] = -86.697163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118984846, states[0] = -86.861600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127103325, states[0] = -15.243628, states[40]= 0.001418
Saving checkpoint... 
Iteration: 135824586, states[0] = -86.758008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144732100, states[0] = -86.550835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153243783, states[0] = -86.589085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162284205, states[0] = -86.690947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170876093, states[0] = -86.808991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179441108, states[0] = -86.845274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187520326, states[0] = 27.875434, states[40]= 0.001833
Saving checkpoint... 
Iteration: 195633646, states[0] = -46.808341, states[40]= 0.000103
Saving checkpoint... 
Iteration: 203958153, states[0] = -86.851104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212718531, states[0] = -86.498821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221488904, states[0] = -86.859620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229689782, states[0] = -86.368629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237983319, states[0] = -86.858120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246815120, states[0] = -86.742919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254968700, states[0] = -86.853999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263014610, states[0] = 28.397246, states[40]= 0.009702
Saving checkpoint... 
Iteration: 270598511, states[0] = -10.131873, states[40]= 0.002202
Saving checkpoint... 
Iteration: 279171715, states[0] = -85.726890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288015394, states[0] = 28.386448, states[40]= 0.007529
Saving checkpoint... 
Iteration: 296689693, states[0] = -86.367692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305179472, states[0] = -86.254113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313489064, states[0] = -86.859100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321914189, states[0] = -86.831925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330221862, states[0] = -86.511106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337751396, states[0] = -86.609991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344261581, states[0] = -86.637661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350838877, states[0] = -86.772773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358525884, states[0] = 26.626220, states[40]= 0.000826
Saving checkpoint... 
Iteration: 366146462, states[0] = -60.928866, states[40]= 0.000012
Saving checkpoint... 
Iteration: 374509519, states[0] = 28.021216, states[40]= 0.053491
Saving checkpoint... 
Iteration: 383108459, states[0] = -20.639296, states[40]= 0.000992
Saving checkpoint... 
Iteration: 391260113, states[0] = -86.633619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399561826, states[0] = 13.046035, states[40]= 0.002287
Saving checkpoint... 
Iteration: 407917098, states[0] = -86.832995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416509477, states[0] = 28.016948, states[40]= 0.054261
Saving checkpoint... 
Iteration: 425397057, states[0] = -86.821684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434171943, states[0] = -85.759361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442789897, states[0] = -86.699998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451130872, states[0] = -43.866223, states[40]= 0.000155
Saving checkpoint... 
Iteration: 459735629, states[0] = -86.560209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468022694, states[0] = 27.414587, states[40]= 0.001150
Saving checkpoint... 
Iteration: 476433009, states[0] = -86.840078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485229706, states[0] = -86.539481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493529804, states[0] = 25.464506, states[40]= 0.000770
Saving checkpoint... 
Iteration: 501484199, states[0] = -86.856996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510354360, states[0] = -86.788113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518944515, states[0] = -86.844529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526860698, states[0] = -86.793920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535320472, states[0] = -86.748991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543473045, states[0] = -86.853819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551567449, states[0] = 10.541459, states[40]= 0.002689
Saving checkpoint... 
Iteration: 560375144, states[0] = -86.805822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569107683, states[0] = -19.815365, states[40]= 0.001031
Saving checkpoint... 
Iteration: 578250917, states[0] = -86.607429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586728038, states[0] = -86.532961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594750118, states[0] = -86.605033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603149693, states[0] = -64.834276, states[40]= 0.000006
Saving checkpoint... 
Iteration: 612081506, states[0] = 3.251873, states[40]= 0.003488
Saving checkpoint... 
Iteration: 620869922, states[0] = -86.801373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629206335, states[0] = -86.445789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637628677, states[0] = -41.570761, states[40]= 0.000211
Saving checkpoint... 
Iteration: 646498395, states[0] = -86.859597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654681818, states[0] = -86.296272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663211988, states[0] = -86.469775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672099330, states[0] = -10.962650, states[40]= 0.002057
Saving checkpoint... 
Iteration: 680494594, states[0] = -86.858599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688807658, states[0] = -86.729467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697319734, states[0] = -86.747190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705265246, states[0] = -86.645142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713642921, states[0] = -56.865389, states[40]= 0.000022
Saving checkpoint... 
Iteration: 721887902, states[0] = -86.814306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730518922, states[0] = 28.092936, states[40]= 0.002617
Saving checkpoint... 
Iteration: 738451666, states[0] = -86.846096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747130247, states[0] = -43.208730, states[40]= 0.000169
Saving checkpoint... 
Iteration: 755233865, states[0] = -86.552743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763487781, states[0] = -86.856613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772245347, states[0] = -86.589929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781117444, states[0] = -29.988273, states[40]= 0.000700
Saving checkpoint... 
Iteration: 789578873, states[0] = 4.774374, states[40]= 0.003391
Saving checkpoint... 
Iteration: 797892232, states[0] = -86.816819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806191318, states[0] = -86.374260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815109753, states[0] = -22.001396, states[40]= 0.000943
Saving checkpoint... 
Iteration: 823846795, states[0] = -86.779042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832659752, states[0] = -78.160684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841107035, states[0] = -19.124491, states[40]= 0.001070
Saving checkpoint... 
Iteration: 850059182, states[0] = 14.176943, states[40]= 0.002101
Saving checkpoint... 
Iteration: 858238191, states[0] = -86.566791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867264320, states[0] = -86.642046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875630763, states[0] = -43.748421, states[40]= 0.000157
Saving checkpoint... 
Iteration: 884217840, states[0] = -86.492597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892796834, states[0] = -86.710483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901275229, states[0] = -86.667612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910138052, states[0] = -51.509790, states[40]= 0.000051
Saving checkpoint... 
Iteration: 918655787, states[0] = -72.874183, states[40]= 0.000002
Saving checkpoint... 
Iteration: 927113745, states[0] = -26.165999, states[40]= 0.000838
Saving checkpoint... 
Iteration: 935788360, states[0] = -86.694653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944329031, states[0] = -86.758198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953005797, states[0] = 28.491846, states[40]= 0.189592
Saving checkpoint... 
Iteration: 961576749, states[0] = 5.939418, states[40]= 0.003288
Saving checkpoint... 
Iteration: 969785090, states[0] = -86.688068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977906436, states[0] = -86.824552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986717427, states[0] = -86.490440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995304764, states[0] = -86.723367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003825565, states[0] = -86.753497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012606625, states[0] = -18.686512, states[40]= 0.001098
Saving checkpoint... 
Iteration: 1021615045, states[0] = -27.511010, states[40]= 0.000797
Saving checkpoint... 
Iteration: 1030699916, states[0] = -86.415119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039093375, states[0] = -5.265050, states[40]= 0.003033
Saving checkpoint... 
Iteration: 1047828026, states[0] = -86.756433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055994688, states[0] = -86.856808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064543312, states[0] = 20.581253, states[40]= 0.001177
Saving checkpoint... 
Iteration: 1072641973, states[0] = -55.803248, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1080800876, states[0] = -86.716531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089158456, states[0] = -76.490754, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1097852844, states[0] = -86.783799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106225183, states[0] = -86.519871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114938167, states[0] = -86.839149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123266627, states[0] = -86.646490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131652157, states[0] = -67.977757, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1140034232, states[0] = 23.973751, states[40]= 0.000850
Saving checkpoint... 
Iteration: 1148774846, states[0] = -86.665549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157821134, states[0] = -86.746867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165967348, states[0] = -86.849154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174383566, states[0] = -86.809101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182655509, states[0] = -72.488421, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1191270772, states[0] = -86.656045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199669130, states[0] = -85.171474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208101474, states[0] = -13.193219, states[40]= 0.001697
Saving checkpoint... 
Iteration: 1215814936, states[0] = -86.737882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223897208, states[0] = -86.817915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232180218, states[0] = -86.265550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240957092, states[0] = -86.845538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249506874, states[0] = 28.041046, states[40]= 0.131602
Saving checkpoint... 
Iteration: 1258120039, states[0] = -32.655603, states[40]= 0.000573
Saving checkpoint... 
Iteration: 1266563851, states[0] = 12.163794, states[40]= 0.002431
Saving checkpoint... 
Iteration: 1275081884, states[0] = 3.027671, states[40]= 0.003498
Saving checkpoint... 
Iteration: 1283589921, states[0] = -2.425618, states[40]= 0.003377
Saving checkpoint... 
Iteration: 1292338491, states[0] = -86.767765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301350815, states[0] = -86.780813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310037127, states[0] = 22.928441, states[40]= 0.000936
Saving checkpoint... 
Iteration: 1318293087, states[0] = -86.701677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326907801, states[0] = -86.823627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335389949, states[0] = -86.812715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344094224, states[0] = -6.015635, states[40]= 0.002917
Saving checkpoint... 
Iteration: 1352986351, states[0] = -86.853421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361440176, states[0] = -86.838768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369811740, states[0] = -86.732416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378096544, states[0] = -8.178858, states[40]= 0.002549
Saving checkpoint... 
Iteration: 1386549854, states[0] = 18.002616, states[40]= 0.001507
Saving checkpoint... 
Iteration: 1394607012, states[0] = -19.096084, states[40]= 0.001072
Saving checkpoint... 
Iteration: 1403566078, states[0] = 11.169314, states[40]= 0.002591
Saving checkpoint... 
Iteration: 1411894425, states[0] = -86.815259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420342853, states[0] = -86.771971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428256806, states[0] = -86.619730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436612744, states[0] = -25.123345, states[40]= 0.000865
Saving checkpoint... 
Iteration: 1445012786, states[0] = 28.342016, states[40]= 0.017731
Saving checkpoint... 
Iteration: 1453577420, states[0] = 5.578574, states[40]= 0.003322
Saving checkpoint... 
Iteration: 1462012821, states[0] = 28.344194, states[40]= 0.017525
Saving checkpoint... 
Iteration: 1471089703, states[0] = -2.257136, states[40]= 0.003392
Saving checkpoint... 
Iteration: 1480276637, states[0] = -86.667888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489097032, states[0] = -8.652018, states[40]= 0.002465
Saving checkpoint... 
Iteration: 1497105184, states[0] = -17.144165, states[40]= 0.001220
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.731697
 - CaMKt in component CaMK (millimolar): 0.012249
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.588675
 - nass in component intracellular_ions (millimolar): 6.588768
 - ki in component intracellular_ions (millimolar): 145.294817
 - kss in component intracellular_ions (millimolar): 145.294796
 - cansr in component intracellular_ions (millimolar): 1.626002
 - cajsr in component intracellular_ions (millimolar): 1.582093
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.008241
 - hf in component INa (dimensionless): 0.657007
 - hs in component INa (dimensionless): 0.656987
 - j in component INa (dimensionless): 0.656872
 - hsp in component INa (dimensionless): 0.408774
 - jp in component INa (dimensionless): 0.656791
 - mL in component INaL (dimensionless): 0.000234
 - hL in component INaL (dimensionless): 0.460344
 - hLp in component INaL (dimensionless): 0.233778
 - a in component Ito (dimensionless): 0.001082
 - iF in component Ito (dimensionless): 0.999455
 - iS in component Ito (dimensionless): 0.568047
 - ap in component Ito (dimensionless): 0.000551
 - iFp in component Ito (dimensionless): 0.999455
 - iSp in component Ito (dimensionless): 0.617214
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.915135
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999836
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002876
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.461038
 - xs1 in component IKs (dimensionless): 0.271796
 - xs2 in component IKs (dimensionless): 0.000219
 - xk1 in component IK1 (dimensionless): 0.997048
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:59:16 (11156): called boinc_finish(0)

</stderr_txt>
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