𝕏

Task 55834796

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-BASE_ENDO-conf_294_1
Workunit 26515526
Created 2 Jul 2024, 14:37:30 UTC
Sent 3 Jul 2024, 5:51:14 UTC
Report deadline 6 Jul 2024, 5:51:14 UTC
Received 4 Jul 2024, 20:07:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214494
Run time 2 hours 56 min 20 sec
CPU time 2 hours 18 min 22 sec
Validate state Valid
Credit 46.37
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.21 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-BASE_ENDO-conf_294.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-BASE_ENDO-conf_294_1_r1338560939_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-BASE_ENDO-conf_294_1_r1338560939_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 103.777374
     * GNaL_b in INaL: 0.006085
     * Gto_b in Ito: 0.086306
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032074
     * GKs_b in IKs: 0.001943
     * GK1_b in IK1: 0.166942
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.326310
     * GKb_b in IKb: 0.003832
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030346
     * celltype in environment: 0.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8639801, states[0] = -62.312485, states[40]= 0.000007
Saving checkpoint... 
Iteration: 17628318, states[0] = -45.374198, states[40]= 0.000111
Saving checkpoint... 
Iteration: 25475954, states[0] = -86.945750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33823471, states[0] = -86.832217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41423763, states[0] = -86.903730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50318884, states[0] = -86.809870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58660206, states[0] = -80.834864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67400490, states[0] = -86.876163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76256273, states[0] = -86.677130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84334272, states[0] = -86.815843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92499363, states[0] = -86.906160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101210656, states[0] = -86.517423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109465949, states[0] = -86.895449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116799818, states[0] = -86.763189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124061495, states[0] = 13.080320, states[40]= 0.002335
Saving checkpoint... 
Iteration: 131184778, states[0] = -86.388205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138735632, states[0] = -86.607655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146003843, states[0] = 31.314240, states[40]= 0.359759
Saving checkpoint... 
Iteration: 153924110, states[0] = -86.877107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161695808, states[0] = -86.448313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169988712, states[0] = -86.898421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178004613, states[0] = 29.772229, states[40]= 0.280209
Saving checkpoint... 
Iteration: 185555436, states[0] = 15.661905, states[40]= 0.001922
Saving checkpoint... 
Iteration: 193188332, states[0] = -86.409772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201331739, states[0] = -86.805439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210205004, states[0] = -86.488845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218593076, states[0] = -5.267646, states[40]= 0.003058
Saving checkpoint... 
Iteration: 226664172, states[0] = -83.509547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234388219, states[0] = -86.855956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241437309, states[0] = -86.881560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248206085, states[0] = -86.493215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254738220, states[0] = -86.614191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261375256, states[0] = -86.846583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268386672, states[0] = -86.854709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275233434, states[0] = -86.598270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281914295, states[0] = -86.870876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288705390, states[0] = -86.489987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296155052, states[0] = -73.175095, states[40]= 0.000002
Saving checkpoint... 
Iteration: 303891381, states[0] = -86.857623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311119594, states[0] = -32.641308, states[40]= 0.000570
Saving checkpoint... 
Iteration: 318403141, states[0] = -86.864676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325578609, states[0] = 4.787371, states[40]= 0.003444
Saving checkpoint... 
Iteration: 333185654, states[0] = -86.391793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340076082, states[0] = 6.171637, states[40]= 0.003322
Saving checkpoint... 
Iteration: 347274113, states[0] = -86.710023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354557452, states[0] = 14.828766, states[40]= 0.002059
Saving checkpoint... 
Iteration: 362018312, states[0] = 28.132983, states[40]= 0.003125
Saving checkpoint... 
Iteration: 369339236, states[0] = -86.812997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376629960, states[0] = -43.454753, states[40]= 0.000163
Saving checkpoint... 
Iteration: 383923773, states[0] = -86.874977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391090909, states[0] = -3.434945, states[40]= 0.003304
Saving checkpoint... 
Iteration: 398514872, states[0] = 28.368264, states[40]= 0.008911
Saving checkpoint... 
Iteration: 405609893, states[0] = -22.534007, states[40]= 0.000928
Saving checkpoint... 
Iteration: 413192909, states[0] = -86.432536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420337918, states[0] = -86.811296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427705234, states[0] = -86.488625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435049408, states[0] = 18.112538, states[40]= 0.001550
Saving checkpoint... 
Iteration: 442813858, states[0] = -86.780690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450450082, states[0] = -86.885328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457885533, states[0] = -86.853011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464956909, states[0] = -86.887587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472557879, states[0] = 14.650043, states[40]= 0.002088
Saving checkpoint... 
Iteration: 479944704, states[0] = -86.883237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487211448, states[0] = -86.514610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494651441, states[0] = -68.195542, states[40]= 0.000004
Saving checkpoint... 
Iteration: 502003664, states[0] = 31.787722, states[40]= 0.380252
Saving checkpoint... 
Iteration: 509317563, states[0] = -86.785589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516367918, states[0] = -86.839565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523609058, states[0] = -21.650590, states[40]= 0.000955
Saving checkpoint... 
Iteration: 531098696, states[0] = -10.635765, states[40]= 0.002128
Saving checkpoint... 
Iteration: 538795171, states[0] = -86.750546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546197949, states[0] = -86.455673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553590765, states[0] = -3.317653, states[40]= 0.003318
Saving checkpoint... 
Iteration: 560471792, states[0] = -86.891670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567849289, states[0] = -86.822545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575390653, states[0] = -86.855859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582750448, states[0] = -86.649585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590089702, states[0] = -2.476080, states[40]= 0.003405
Saving checkpoint... 
Iteration: 597560947, states[0] = 13.346338, states[40]= 0.002303
Saving checkpoint... 
Iteration: 604713361, states[0] = -86.521881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611872332, states[0] = -86.842640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619332100, states[0] = -86.803668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627005213, states[0] = 29.000815, states[40]= 0.229448
Saving checkpoint... 
Iteration: 634879417, states[0] = -86.847868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642864423, states[0] = -86.836060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650618789, states[0] = -31.804776, states[40]= 0.000610
Saving checkpoint... 
Iteration: 658183693, states[0] = -86.374742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665406054, states[0] = -86.864668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673258237, states[0] = -86.670359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681865307, states[0] = -86.836620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690381927, states[0] = -86.849405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699476314, states[0] = -86.892258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708346447, states[0] = -86.819024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716641707, states[0] = -56.282282, states[40]= 0.000024
Saving checkpoint... 
Iteration: 724874852, states[0] = -86.844048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733275826, states[0] = -86.711912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741780560, states[0] = -86.721839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749980313, states[0] = -86.893070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758215318, states[0] = -86.529034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766597602, states[0] = -9.525457, states[40]= 0.002325
Saving checkpoint... 
Iteration: 775299830, states[0] = -86.757387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783979893, states[0] = -86.892801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792188032, states[0] = -86.404823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799730890, states[0] = -86.587009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808211078, states[0] = -86.511528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816846568, states[0] = -86.818633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825241193, states[0] = -86.620843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834084213, states[0] = 1.412742, states[40]= 0.003583
Saving checkpoint... 
Iteration: 843137939, states[0] = -52.070581, states[40]= 0.000047
Saving checkpoint... 
Iteration: 852146863, states[0] = -62.332912, states[40]= 0.000009
Saving checkpoint... 
Iteration: 861180986, states[0] = -86.344283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870095496, states[0] = -7.469325, states[40]= 0.002694
Saving checkpoint... 
Iteration: 878220114, states[0] = -86.547259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887092041, states[0] = -4.369621, states[40]= 0.003186
Saving checkpoint... 
Iteration: 895505191, states[0] = 29.023681, states[40]= 0.231139
Saving checkpoint... 
Iteration: 903872186, states[0] = -86.841144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912038789, states[0] = 22.248890, states[40]= 0.001046
Saving checkpoint... 
Iteration: 920849462, states[0] = -86.821044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928964649, states[0] = -86.887845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937477357, states[0] = -86.891414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946166443, states[0] = -84.687013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954950247, states[0] = -86.883007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963538079, states[0] = 22.514851, states[40]= 0.001020
Saving checkpoint... 
Iteration: 972334214, states[0] = -86.804470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981141505, states[0] = -56.050528, states[40]= 0.000025
Saving checkpoint... 
Iteration: 990362286, states[0] = -86.832585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998068958, states[0] = 9.744194, states[40]= 0.002874
Saving checkpoint... 
Iteration: 1006802100, states[0] = -86.760026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014641395, states[0] = -55.925625, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1022948067, states[0] = -86.881909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031291817, states[0] = -86.742214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040162709, states[0] = -82.412278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048477551, states[0] = -86.890942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057445041, states[0] = -86.880638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066302004, states[0] = -86.759586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075187871, states[0] = -86.402489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083176865, states[0] = -86.256228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091327487, states[0] = -86.795831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099933917, states[0] = -86.876053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107927924, states[0] = -86.873438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116394626, states[0] = -86.855825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125065528, states[0] = 11.329307, states[40]= 0.002632
Saving checkpoint... 
Iteration: 1133114068, states[0] = -26.901164, states[40]= 0.000813
Saving checkpoint... 
Iteration: 1142041936, states[0] = 21.050636, states[40]= 0.001173
Saving checkpoint... 
Iteration: 1150333231, states[0] = -86.802481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158577707, states[0] = 5.292439, states[40]= 0.003403
Saving checkpoint... 
Iteration: 1167077537, states[0] = 5.386077, states[40]= 0.003395
Saving checkpoint... 
Iteration: 1175208009, states[0] = -86.496893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183269946, states[0] = -86.696649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192073096, states[0] = 7.723693, states[40]= 0.003148
Saving checkpoint... 
Iteration: 1199868059, states[0] = -86.836447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208459750, states[0] = -86.885001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216714698, states[0] = -86.524333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226198079, states[0] = -86.452973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234606484, states[0] = -18.904598, states[40]= 0.001088
Saving checkpoint... 
Iteration: 1242966158, states[0] = -86.886818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251411052, states[0] = -86.864599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259812078, states[0] = -86.774228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268650361, states[0] = -66.752531, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1276805125, states[0] = -86.763586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284753142, states[0] = -86.653757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293186035, states[0] = -86.389740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302032731, states[0] = 24.440254, states[40]= 0.000860
Saving checkpoint... 
Iteration: 1310502235, states[0] = 37.321335, states[40]= 0.528390
Saving checkpoint... 
Iteration: 1318911646, states[0] = -86.864592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327648078, states[0] = -63.828738, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1336005062, states[0] = 29.165857, states[40]= 0.241317
Saving checkpoint... 
Iteration: 1344642913, states[0] = -57.653952, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1353857989, states[0] = -86.827060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362614071, states[0] = -26.902732, states[40]= 0.000813
Saving checkpoint... 
Iteration: 1370939869, states[0] = -86.877182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379439193, states[0] = -86.876876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387832912, states[0] = -86.800981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396096414, states[0] = -8.348170, states[40]= 0.002538
Saving checkpoint... 
Iteration: 1404370419, states[0] = -86.837382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412771077, states[0] = -86.698141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421396217, states[0] = -86.855366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429958034, states[0] = -86.883403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438453192, states[0] = -86.881748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446995447, states[0] = -86.893374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455567521, states[0] = 10.418083, states[40]= 0.002773
Saving checkpoint... 
Iteration: 1464115538, states[0] = -28.427574, states[40]= 0.000760
Saving checkpoint... 
Iteration: 1472313807, states[0] = -86.775725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480534925, states[0] = 23.670065, states[40]= 0.000917
Saving checkpoint... 
Iteration: 1489489434, states[0] = -86.891817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497586114, states[0] = 0.146821, states[40]= 0.003566
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.769969
 - CaMKt in component CaMK (millimolar): 0.012170
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.591638
 - nass in component intracellular_ions (millimolar): 6.591731
 - ki in component intracellular_ions (millimolar): 145.293519
 - kss in component intracellular_ions (millimolar): 145.293497
 - cansr in component intracellular_ions (millimolar): 1.621653
 - cajsr in component intracellular_ions (millimolar): 1.577868
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.008209
 - hf in component INa (dimensionless): 0.658423
 - hs in component INa (dimensionless): 0.658403
 - j in component INa (dimensionless): 0.658290
 - hsp in component INa (dimensionless): 0.410296
 - jp in component INa (dimensionless): 0.658211
 - mL in component INaL (dimensionless): 0.000232
 - hL in component INaL (dimensionless): 0.461772
 - hLp in component INaL (dimensionless): 0.235051
 - a in component Ito (dimensionless): 0.001079
 - iF in component Ito (dimensionless): 0.999459
 - iS in component Ito (dimensionless): 0.568986
 - ap in component Ito (dimensionless): 0.000550
 - iFp in component Ito (dimensionless): 0.999459
 - iSp in component Ito (dimensionless): 0.618429
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.915494
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999837
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002853
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.459660
 - xs1 in component IKs (dimensionless): 0.271060
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997038
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:07:13 (10660): called boinc_finish(0)

</stderr_txt>
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