𝕏

Task 55834478

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593_1
Workunit 26515367
Created 2 Jul 2024, 14:37:24 UTC
Sent 3 Jul 2024, 5:50:25 UTC
Report deadline 6 Jul 2024, 5:50:25 UTC
Received 3 Jul 2024, 11:15:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220141
Run time 1 hours 5 min 45 sec
CPU time 1 hours 4 min 43 sec
Validate state Valid
Credit 47.14
Device peak FLOPS 4.30 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.71 MB
Peak swap size 6.26 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593_1_r2100598790_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593_1_r2100598790_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.119970
     * GNaL_b in INaL: 0.005893
     * Gto_b in Ito: 0.082962
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031989
     * GKs_b in IKs: 0.001975
     * GK1_b in IK1: 0.160583
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.666234
     * GKb_b in IKb: 0.003827
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030263
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 23803293, states[0] = -94.346935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47752109, states[0] = -94.344820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71951519, states[0] = -94.347654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95908066, states[0] = -94.360819, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593_1_r2100598790_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593_1_r2100598790_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.119970
     * GNaL_b in INaL: 0.005893
     * Gto_b in Ito: 0.082962
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031989
     * GKs_b in IKs: 0.001975
     * GK1_b in IK1: 0.160583
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.666234
     * GKb_b in IKb: 0.003827
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030263
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 95908066
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.360819 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 121070865, states[0] = 16.504792, states[40]= 0.000008
Saving checkpoint... 
Iteration: 146321993, states[0] = -94.226933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171562142, states[0] = -94.380557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196846511, states[0] = -94.373608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222123995, states[0] = -24.747867, states[40]= 0.000468


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593_1_r2100598790_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593_1_r2100598790_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.119970
     * GNaL_b in INaL: 0.005893
     * Gto_b in Ito: 0.082962
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031989
     * GKs_b in IKs: 0.001975
     * GK1_b in IK1: 0.160583
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.666234
     * GKb_b in IKb: 0.003827
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030263
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 222123995
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -24.747867 (After loading)
 - states[40]: 0.000468 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 246571593, states[0] = -94.380315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271605259, states[0] = -94.381137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296672945, states[0] = -94.380179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321793785, states[0] = -94.373876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347055954, states[0] = 21.864041, states[40]= 0.000001
Saving checkpoint... 
Iteration: 372098932, states[0] = 0.580767, states[40]= 0.000232
Saving checkpoint... 
Iteration: 397282582, states[0] = -94.123000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422465057, states[0] = -94.356085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447677164, states[0] = -94.375808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472696644, states[0] = -94.374455, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593_1_r2100598790_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593_1_r2100598790_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.119970
     * GNaL_b in INaL: 0.005893
     * Gto_b in Ito: 0.082962
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031989
     * GKs_b in IKs: 0.001975
     * GK1_b in IK1: 0.160583
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.666234
     * GKb_b in IKb: 0.003827
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030263
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 472696644
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.374455 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 494688361, states[0] = -94.374123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517752867, states[0] = -94.370612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540497766, states[0] = -94.362042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563369725, states[0] = -94.289095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586122137, states[0] = -22.699662, states[40]= 0.000414
Saving checkpoint... 
Iteration: 609120619, states[0] = -21.015153, states[40]= 0.000377
Saving checkpoint... 
Iteration: 632097468, states[0] = 1.653297, states[40]= 0.000204
Saving checkpoint... 
Iteration: 654975604, states[0] = -94.353048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678369262, states[0] = -94.285290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701533524, states[0] = -94.363792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724594718, states[0] = -94.367995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747740170, states[0] = -94.364709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770962151, states[0] = -94.350585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794168971, states[0] = -81.051850, states[40]= 0.000002
Saving checkpoint... 
Iteration: 817225546, states[0] = -93.844328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840313317, states[0] = -94.191931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863383043, states[0] = -94.294160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886558521, states[0] = -94.361255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910258503, states[0] = -94.018138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933734441, states[0] = -94.359710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956835866, states[0] = -94.353272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979844035, states[0] = -94.352100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002881858, states[0] = -94.349054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025924559, states[0] = -94.345686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048973689, states[0] = -94.341940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072097021, states[0] = 1.979463, states[40]= 0.000196
Saving checkpoint... 
Iteration: 1095072537, states[0] = 15.663470, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1118160650, states[0] = -68.163904, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1141752707, states[0] = -94.352872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164854333, states[0] = -94.346198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187984664, states[0] = -94.337314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211176050, states[0] = -90.681387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234345224, states[0] = -94.238401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257246258, states[0] = -93.950621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279241052, states[0] = -93.922763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301750176, states[0] = -94.348448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324945491, states[0] = -94.335854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347634867, states[0] = -94.350889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371682756, states[0] = -94.349353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394900221, states[0] = -94.336725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417997239, states[0] = -94.329981, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593_1_r2100598790_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_2000-conf_593_1_r2100598790_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.119970
     * GNaL_b in INaL: 0.005893
     * Gto_b in Ito: 0.082962
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031989
     * GKs_b in IKs: 0.001975
     * GK1_b in IK1: 0.160583
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.666234
     * GKb_b in IKb: 0.003827
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030263
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1417997239
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.329981 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1440914139, states[0] = -94.334529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464141405, states[0] = -44.732300, states[40]= 0.000235
Saving checkpoint... 
Iteration: 1487255752, states[0] = -93.989220, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.203426
 - CaMKt in component CaMK (millimolar): 0.007296
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 7.444538
 - nass in component intracellular_ions (millimolar): 7.444685
 - ki in component intracellular_ions (millimolar): 144.065322
 - kss in component intracellular_ions (millimolar): 144.065299
 - cansr in component intracellular_ions (millimolar): 2.607894
 - cajsr in component intracellular_ions (millimolar): 2.608813
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003883
 - hf in component INa (dimensionless): 0.867343
 - hs in component INa (dimensionless): 0.867346
 - j in component INa (dimensionless): 0.867360
 - hsp in component INa (dimensionless): 0.702453
 - jp in component INa (dimensionless): 0.867368
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.710356
 - hLp in component INaL (dimensionless): 0.502170
 - a in component Ito (dimensionless): 0.000654
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.999853
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.999853
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.974676
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005470
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.092524
 - xs1 in component IKs (dimensionless): 0.127914
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997514
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:18:21 (9784): called boinc_finish(0)

</stderr_txt>
]]>