𝕏

Task 55833920

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_ENDO_4000-conf_392_1
Workunit 26515088
Created 2 Jul 2024, 14:37:09 UTC
Sent 3 Jul 2024, 5:46:20 UTC
Report deadline 6 Jul 2024, 5:46:20 UTC
Received 3 Jul 2024, 13:26:45 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 35 min 21 sec
CPU time 1 hours 32 min 46 sec
Validate state Valid
Credit 43.22
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.76 MB
Peak swap size 4.13 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_ENDO_4000-conf_392.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_ENDO_4000-conf_392_1_r627073809_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_ENDO_4000-conf_392_1_r627073809_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.548270
     * GNaL_b in INaL: 0.005765
     * Gto_b in Ito: 0.085746
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031631
     * GKs_b in IKs: 0.001910
     * GK1_b in IK1: 0.161313
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.983586
     * GKb_b in IKb: 0.003827
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030583
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13050339, states[0] = -94.031470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25818843, states[0] = -93.939544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38349216, states[0] = -93.752744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50784699, states[0] = -93.934653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63557449, states[0] = -93.905130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75787384, states[0] = -93.898371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86475916, states[0] = -93.877379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99363266, states[0] = -93.908437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111546211, states[0] = -93.902769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124358102, states[0] = -93.750229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136297210, states[0] = -93.598991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148155110, states[0] = -35.055603, states[40]= 0.001532
Saving checkpoint... 
Iteration: 161215966, states[0] = -93.913001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173440808, states[0] = -93.905271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186160042, states[0] = -38.755310, states[40]= 0.001034
Saving checkpoint... 
Iteration: 198982849, states[0] = -93.922285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210757308, states[0] = -93.928164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223623443, states[0] = -93.900118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236379188, states[0] = -93.783979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249427818, states[0] = -93.905416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261297104, states[0] = -93.909686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274101796, states[0] = 3.570325, states[40]= 0.003300
Saving checkpoint... 
Iteration: 287160169, states[0] = -93.914767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300677985, states[0] = -93.925663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313557514, states[0] = -93.901558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326928204, states[0] = -93.924070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340119982, states[0] = -8.031848, states[40]= 0.002821
Saving checkpoint... 
Iteration: 353198919, states[0] = -93.913083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365535310, states[0] = -93.902023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378427741, states[0] = -93.840311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391875646, states[0] = -93.894303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404354082, states[0] = -93.741852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417462131, states[0] = -93.903963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430352182, states[0] = -93.738190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443629449, states[0] = -93.899411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456375372, states[0] = -93.777727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468832433, states[0] = -93.926697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481860440, states[0] = -93.894364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495154447, states[0] = -93.914479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507915711, states[0] = -93.893291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520262581, states[0] = -93.462386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533361092, states[0] = -93.906827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546310512, states[0] = -93.639051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559070179, states[0] = -93.917762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571526724, states[0] = -93.901748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584744286, states[0] = -93.927125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597235552, states[0] = -93.911088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609835916, states[0] = -93.894516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623373584, states[0] = -93.906196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636207388, states[0] = -80.447113, states[40]= 0.000002
Saving checkpoint... 
Iteration: 649388192, states[0] = -93.905661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662655370, states[0] = -93.923171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675956246, states[0] = -93.892173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688333519, states[0] = -93.698334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700181899, states[0] = -55.749402, states[40]= 0.000098
Saving checkpoint... 
Iteration: 713447079, states[0] = -93.903679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725858058, states[0] = -93.893806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739319237, states[0] = -93.907730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751867439, states[0] = -93.893566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765924797, states[0] = -93.892493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780754478, states[0] = -93.926723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792148951, states[0] = -30.482230, states[40]= 0.002188
Saving checkpoint... 
Iteration: 805911901, states[0] = -93.892622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821867986, states[0] = -93.893383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838057095, states[0] = 22.218047, states[40]= 0.000477
Saving checkpoint... 
Iteration: 854253401, states[0] = -93.418753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868012660, states[0] = 31.123050, states[40]= 0.023563
Saving checkpoint... 
Iteration: 868057991, states[0] = 21.901288, states[40]= 0.000502
Saving checkpoint... 
Iteration: 879606115, states[0] = -93.898910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892633206, states[0] = -93.920463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904947611, states[0] = -93.921909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917791003, states[0] = -93.894645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930679415, states[0] = -93.924194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943798771, states[0] = -93.894424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956511419, states[0] = -93.891659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970025367, states[0] = 31.044658, states[40]= 0.000361
Saving checkpoint... 
Iteration: 983382318, states[0] = -93.905026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996077677, states[0] = 14.455035, states[40]= 0.001409
Saving checkpoint... 
Iteration: 1008948470, states[0] = -93.921620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021781100, states[0] = -93.894590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034230081, states[0] = -93.212145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047004212, states[0] = -93.919292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059988490, states[0] = -93.890687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073394707, states[0] = -93.904408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086779414, states[0] = -93.925960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100556234, states[0] = -93.906185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114081681, states[0] = 12.818738, states[40]= 0.001689
Saving checkpoint... 
Iteration: 1127628602, states[0] = -93.897743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141204220, states[0] = -93.910936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154081983, states[0] = 12.693396, states[40]= 0.001712
Saving checkpoint... 
Iteration: 1166326270, states[0] = -93.679817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179800213, states[0] = -93.893812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193340266, states[0] = -93.905894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206398775, states[0] = -93.807671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220300454, states[0] = -93.606636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233477358, states[0] = -93.901505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246528115, states[0] = -93.897273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259422222, states[0] = -93.903088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272324738, states[0] = -93.675726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286006890, states[0] = 30.031038, states[40]= 0.174807
Saving checkpoint... 
Iteration: 1299439330, states[0] = -93.902467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313035172, states[0] = -93.917357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325863593, states[0] = -93.892221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339283005, states[0] = -93.907522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351777647, states[0] = -93.893847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364831654, states[0] = -93.924509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377805831, states[0] = -93.893210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390579521, states[0] = -93.910911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403675774, states[0] = -93.895942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416567029, states[0] = -93.908093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429172404, states[0] = -93.911465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442679163, states[0] = -93.922919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454522585, states[0] = -93.894778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466857019, states[0] = -93.923620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479028014, states[0] = -93.917245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492790609, states[0] = -93.924873, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.765382
 - CaMKt in component CaMK (millimolar): 0.002090
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.727681
 - nass in component intracellular_ions (millimolar): 6.727805
 - ki in component intracellular_ions (millimolar): 145.129772
 - kss in component intracellular_ions (millimolar): 145.129761
 - cansr in component intracellular_ions (millimolar): 1.835877
 - cajsr in component intracellular_ions (millimolar): 1.835725
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004058
 - hf in component INa (dimensionless): 0.858840
 - hs in component INa (dimensionless): 0.858841
 - j in component INa (dimensionless): 0.858845
 - hsp in component INa (dimensionless): 0.687181
 - jp in component INa (dimensionless): 0.858847
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.698221
 - hLp in component INaL (dimensionless): 0.502189
 - a in component Ito (dimensionless): 0.000673
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.991341
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.996512
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996437
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005297
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008224
 - xs1 in component IKs (dimensionless): 0.041598
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997620
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:25:37 (28924): called boinc_finish(0)

</stderr_txt>
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