𝕏

Task 55833866

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_1000-conf_592_1
Workunit 26515061
Created 2 Jul 2024, 14:37:08 UTC
Sent 3 Jul 2024, 5:46:20 UTC
Report deadline 6 Jul 2024, 5:46:20 UTC
Received 3 Jul 2024, 7:59:40 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 38 min 19 sec
CPU time 1 hours 32 min 21 sec
Validate state Valid
Credit 42.30
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.89 MB
Peak swap size 4.13 GB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_1000-conf_592.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_1000-conf_592_1_r497122751_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_1000-conf_592_1_r497122751_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.718320
     * GNaL_b in INaL: 0.005702
     * Gto_b in Ito: 0.082658
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031880
     * GKs_b in IKs: 0.001893
     * GK1_b in IK1: 0.162291
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.543571
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031069
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13242115, states[0] = -94.763076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26457445, states[0] = -94.950463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39459873, states[0] = -94.940556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52740384, states[0] = -94.681473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65432579, states[0] = -94.924535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78351301, states[0] = -94.872522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91085790, states[0] = -0.565813, states[40]= 0.004508
Saving checkpoint... 
Iteration: 103441565, states[0] = -94.925226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116596230, states[0] = -9.095333, states[40]= 0.002888
Saving checkpoint... 
Iteration: 129316642, states[0] = -94.832032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141208637, states[0] = -94.561329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153581527, states[0] = 2.288033, states[40]= 0.004695
Saving checkpoint... 
Iteration: 166293264, states[0] = -94.796479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178635826, states[0] = -47.904330, states[40]= 0.000125
Saving checkpoint... 
Iteration: 191780810, states[0] = -94.773662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204568084, states[0] = 9.621272, states[40]= 0.004279
Saving checkpoint... 
Iteration: 217240165, states[0] = -94.673930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230565184, states[0] = 10.994115, states[40]= 0.004086
Saving checkpoint... 
Iteration: 243982830, states[0] = -94.935826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256800890, states[0] = -94.808357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269642034, states[0] = -54.461821, states[40]= 0.000046
Saving checkpoint... 
Iteration: 282842161, states[0] = -94.860385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296398670, states[0] = -94.903569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309489284, states[0] = -94.937045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322323551, states[0] = -94.839502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335229876, states[0] = -94.640375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348951206, states[0] = -94.926429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361796239, states[0] = -94.800481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374484598, states[0] = -94.935713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387460679, states[0] = -94.929276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400364810, states[0] = -94.880284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412896293, states[0] = -94.901744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426181136, states[0] = -94.299840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438581185, states[0] = 2.507722, states[40]= 0.004701
Saving checkpoint... 
Iteration: 450687770, states[0] = -94.448361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462641250, states[0] = -53.621716, states[40]= 0.000053
Saving checkpoint... 
Iteration: 475032928, states[0] = 23.704985, states[40]= 0.001771
Saving checkpoint... 
Iteration: 487423038, states[0] = -94.915039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500188568, states[0] = -94.455805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512908758, states[0] = -94.908140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526019450, states[0] = 27.224092, states[40]= 0.003152
Saving checkpoint... 
Iteration: 538894390, states[0] = -94.900132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552343139, states[0] = -94.860295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565710744, states[0] = -94.567941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578826391, states[0] = -94.841915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591394323, states[0] = -94.899885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603772972, states[0] = -94.756038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616009211, states[0] = 28.018365, states[40]= 0.063565
Saving checkpoint... 
Iteration: 628874044, states[0] = -94.886419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642337385, states[0] = -94.854018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655782659, states[0] = -94.775287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668574980, states[0] = 6.096506, states[40]= 0.004622
Saving checkpoint... 
Iteration: 681687337, states[0] = -94.442832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693923781, states[0] = -94.914552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706821302, states[0] = -94.835187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719058714, states[0] = 13.873590, states[40]= 0.003591
Saving checkpoint... 
Iteration: 732297199, states[0] = -94.800579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744757482, states[0] = -94.719710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757864353, states[0] = -94.878506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770470608, states[0] = -94.930612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783730390, states[0] = -94.640320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796855970, states[0] = -94.871327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809818830, states[0] = -94.831635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822253278, states[0] = -94.708591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835632195, states[0] = -44.144612, states[40]= 0.000212
Saving checkpoint... 
Iteration: 848652952, states[0] = -66.815725, states[40]= 0.000006
Saving checkpoint... 
Iteration: 861413647, states[0] = -94.909204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873855489, states[0] = -94.870601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887285836, states[0] = -94.780312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900268741, states[0] = -94.745689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912810607, states[0] = -94.820151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925716957, states[0] = -94.591196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938374532, states[0] = -94.885550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951340229, states[0] = -94.855767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964392106, states[0] = -94.897087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977217811, states[0] = -94.594274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990321316, states[0] = -94.834083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003324754, states[0] = -94.838270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016500076, states[0] = -85.577443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029046865, states[0] = 18.671201, states[40]= 0.002634
Saving checkpoint... 
Iteration: 1042307165, states[0] = -94.814705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055063597, states[0] = 11.723461, states[40]= 0.003971
Saving checkpoint... 
Iteration: 1068034006, states[0] = 23.347453, states[40]= 0.001820
Saving checkpoint... 
Iteration: 1080517933, states[0] = 27.449832, states[40]= 0.004407
Saving checkpoint... 
Iteration: 1093344093, states[0] = -94.859104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106186433, states[0] = -94.430293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119693090, states[0] = -94.484974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132765706, states[0] = -94.737917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145187447, states[0] = -94.442131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157361049, states[0] = -94.874231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169165676, states[0] = -85.808379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181764325, states[0] = -94.734529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194444997, states[0] = -94.920964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206799433, states[0] = -94.802285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220216953, states[0] = -94.590002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232781326, states[0] = -94.770440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245403320, states[0] = -94.902392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257741475, states[0] = -94.673689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270407472, states[0] = -94.904490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282877590, states[0] = -94.886367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295236612, states[0] = -94.658584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307804259, states[0] = -94.809344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320550365, states[0] = 17.305677, states[40]= 0.002909
Saving checkpoint... 
Iteration: 1334109016, states[0] = -21.588279, states[40]= 0.001247
Saving checkpoint... 
Iteration: 1347627539, states[0] = -39.466969, states[40]= 0.000390
Saving checkpoint... 
Iteration: 1360992774, states[0] = -94.933664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374211003, states[0] = -94.565759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387454844, states[0] = -94.923521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401160563, states[0] = -77.526854, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414470064, states[0] = -94.927925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427234544, states[0] = -94.651456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440758212, states[0] = -94.718766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453872131, states[0] = -94.881756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467278454, states[0] = -94.763872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480988593, states[0] = -94.932271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492387024, states[0] = -94.891847, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.810489
 - CaMKt in component CaMK (millimolar): 0.012752
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.749862
 - nass in component intracellular_ions (millimolar): 6.749960
 - ki in component intracellular_ions (millimolar): 145.130298
 - kss in component intracellular_ions (millimolar): 145.130276
 - cansr in component intracellular_ions (millimolar): 1.671855
 - cajsr in component intracellular_ions (millimolar): 1.630330
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003652
 - hf in component INa (dimensionless): 0.878406
 - hs in component INa (dimensionless): 0.878398
 - j in component INa (dimensionless): 0.878347
 - hsp in component INa (dimensionless): 0.722812
 - jp in component INa (dimensionless): 0.878312
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.705060
 - hLp in component INaL (dimensionless): 0.442548
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.612256
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.683228
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916523
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999836
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003091
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.365399
 - xs1 in component IKs (dimensionless): 0.266311
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997361
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:52:34 (26854): called boinc_finish(0)

</stderr_txt>
]]>


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