𝕏

Task 55832755

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_8000-conf_489_0
Workunit 26514506
Created 2 Jul 2024, 14:36:37 UTC
Sent 3 Jul 2024, 5:46:20 UTC
Report deadline 6 Jul 2024, 5:46:20 UTC
Received 3 Jul 2024, 7:59:40 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 39 min 56 sec
CPU time 1 hours 33 min 27 sec
Validate state Valid
Credit 46.58
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.98 MB
Peak swap size 4.13 GB
Peak disk usage 2.46 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_8000-conf_489.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_8000-conf_489_0_r124860902_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_8000-conf_489_0_r124860902_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.776597
     * GNaL_b in INaL: 0.005558
     * Gto_b in Ito: 0.083872
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032118
     * GKs_b in IKs: 0.001917
     * GK1_b in IK1: 0.160859
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.493518
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030082
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 375.000000
     * CL_0 in membrane: 8000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1496000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12772362, states[0] = -84.105432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 25140574, states[0] = -83.979111, states[40]= 0.000001
Saving checkpoint... 
Iteration: 38037811, states[0] = -83.888703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50381604, states[0] = -83.847374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 63393015, states[0] = -83.817053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 74816695, states[0] = -83.805315, states[40]= 0.000001
Saving checkpoint... 
Iteration: 87373566, states[0] = -83.791740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 100163011, states[0] = -45.413833, states[40]= 0.000136
Saving checkpoint... 
Iteration: 113353013, states[0] = -83.807094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 125855343, states[0] = -83.788238, states[40]= 0.000001
Saving checkpoint... 
Iteration: 137630341, states[0] = -83.791029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 149938711, states[0] = -83.781668, states[40]= 0.000001
Saving checkpoint... 
Iteration: 162657387, states[0] = -83.771084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 175516882, states[0] = -83.765735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188448741, states[0] = -83.736429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201236898, states[0] = -83.798959, states[40]= 0.000001
Saving checkpoint... 
Iteration: 214022772, states[0] = -83.775280, states[40]= 0.000001
Saving checkpoint... 
Iteration: 226558718, states[0] = -83.768285, states[40]= 0.000001
Saving checkpoint... 
Iteration: 238664086, states[0] = -83.767171, states[40]= 0.000001
Saving checkpoint... 
Iteration: 251739882, states[0] = -83.762313, states[40]= 0.000001
Saving checkpoint... 
Iteration: 265017007, states[0] = -83.808175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 277790464, states[0] = -83.778838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 290110359, states[0] = -83.772683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303296869, states[0] = -83.763143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 315728660, states[0] = -83.761846, states[40]= 0.000001
Saving checkpoint... 
Iteration: 328918723, states[0] = -83.812387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 342172984, states[0] = -83.771547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 355021245, states[0] = -83.764139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 367112236, states[0] = -83.763683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 380056078, states[0] = 21.443887, states[40]= 0.000109
Saving checkpoint... 
Iteration: 392178007, states[0] = -57.084677, states[40]= 0.000025
Saving checkpoint... 
Iteration: 405477135, states[0] = -83.787369, states[40]= 0.000001
Saving checkpoint... 
Iteration: 416479237, states[0] = -83.756733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 429713161, states[0] = -83.780254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 442635657, states[0] = -83.766414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 456063081, states[0] = 18.885664, states[40]= 0.000163
Saving checkpoint... 
Iteration: 468402371, states[0] = -83.683570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 479815843, states[0] = -83.761327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 491494004, states[0] = -83.762101, states[40]= 0.000001
Saving checkpoint... 
Iteration: 503421628, states[0] = -83.762303, states[40]= 0.000001
Saving checkpoint... 
Iteration: 515617797, states[0] = -83.761731, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528347638, states[0] = -83.587117, states[40]= 0.000001
Saving checkpoint... 
Iteration: 540795138, states[0] = -83.815711, states[40]= 0.000001
Saving checkpoint... 
Iteration: 554041345, states[0] = -83.773229, states[40]= 0.000001
Saving checkpoint... 
Iteration: 567026710, states[0] = -83.763782, states[40]= 0.000001
Saving checkpoint... 
Iteration: 580206549, states[0] = -81.604181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592587416, states[0] = -83.800149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 605169907, states[0] = -83.799822, states[40]= 0.000001
Saving checkpoint... 
Iteration: 617839618, states[0] = -83.777002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 630169764, states[0] = -83.771145, states[40]= 0.000001
Saving checkpoint... 
Iteration: 643277535, states[0] = -83.762604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 656276926, states[0] = -83.356376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668577300, states[0] = -83.797649, states[40]= 0.000001
Saving checkpoint... 
Iteration: 681765765, states[0] = -83.778602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 694193064, states[0] = -83.770732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 706881099, states[0] = -83.764376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 719989391, states[0] = -83.760670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 732230998, states[0] = -83.115057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744527724, states[0] = -83.781497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756851242, states[0] = -83.814221, states[40]= 0.000001
Saving checkpoint... 
Iteration: 769691794, states[0] = -83.780343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 782500026, states[0] = -83.767114, states[40]= 0.000001
Saving checkpoint... 
Iteration: 795143053, states[0] = -83.762935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 807212594, states[0] = -83.762630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819516616, states[0] = -83.761589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 832817272, states[0] = -83.814971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 845391325, states[0] = -83.789899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 858288941, states[0] = -83.769268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 871607784, states[0] = -83.761273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 883893409, states[0] = -83.760622, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897068662, states[0] = -83.804395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 910098278, states[0] = -83.771827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 922390916, states[0] = -83.768016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 935347587, states[0] = -83.761958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 948350763, states[0] = -83.593526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 961826121, states[0] = -83.776832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 974361461, states[0] = -83.768266, states[40]= 0.000001
Saving checkpoint... 
Iteration: 987921465, states[0] = -83.760428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1000378185, states[0] = -83.646442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013966654, states[0] = -83.773917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1027155612, states[0] = -83.762566, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1039965507, states[0] = -83.760277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1052799456, states[0] = -83.814968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1064208419, states[0] = -82.061802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077367730, states[0] = -83.790506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1089127798, states[0] = -83.801208, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1101404233, states[0] = -83.789060, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1114064771, states[0] = -83.772083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126573089, states[0] = -83.765995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1138968963, states[0] = -83.763300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1151652545, states[0] = -83.760780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1165042127, states[0] = -83.805355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1177122170, states[0] = -83.801365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190394403, states[0] = -83.767615, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1202491567, states[0] = -83.766623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215472269, states[0] = -83.761180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1227164839, states[0] = -83.762255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1239585873, states[0] = -83.760830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1252091286, states[0] = 7.699214, states[40]= 0.000710
Saving checkpoint... 
Iteration: 1264430687, states[0] = -83.715698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1277253539, states[0] = -83.795043, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1290978885, states[0] = -83.763041, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1303817056, states[0] = -83.760203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1316527018, states[0] = -83.780435, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1330081947, states[0] = -83.771514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1342975188, states[0] = -83.762990, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1355174616, states[0] = -83.762041, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368250066, states[0] = -83.223167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380587045, states[0] = -83.799003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1393219563, states[0] = -83.796426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1405152513, states[0] = -83.799578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1418860233, states[0] = -83.763533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1431754177, states[0] = -83.760163, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1444410473, states[0] = -83.692669, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1457729744, states[0] = -83.778434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1470057044, states[0] = -83.771726, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483002542, states[0] = -83.762659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1495981369, states[0] = -83.759630, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -83.635577
 - CaMKt in component CaMK (millimolar): 0.000862
 - cass in component intracellular_ions (millimolar): 0.000091
 - nai in component intracellular_ions (millimolar): 6.124085
 - nass in component intracellular_ions (millimolar): 6.124192
 - ki in component intracellular_ions (millimolar): 145.781201
 - kss in component intracellular_ions (millimolar): 145.781192
 - cansr in component intracellular_ions (millimolar): 1.644380
 - cajsr in component intracellular_ions (millimolar): 1.644393
 - cai in component intracellular_ions (millimolar): 0.000095
 - m in component INa (dimensionless): 0.011243
 - hf in component INa (dimensionless): 0.535252
 - hs in component INa (dimensionless): 0.535252
 - j in component INa (dimensionless): 0.535253
 - hsp in component INa (dimensionless): 0.293699
 - jp in component INa (dimensionless): 0.535253
 - mL in component INaL (dimensionless): 0.000421
 - hL in component INaL (dimensionless): 0.374213
 - hLp in component INaL (dimensionless): 0.207164
 - a in component Ito (dimensionless): 0.001332
 - iF in component Ito (dimensionless): 0.999064
 - iS in component Ito (dimensionless): 0.998862
 - ap in component Ito (dimensionless): 0.000679
 - iFp in component Ito (dimensionless): 0.999064
 - iSp in component Ito (dimensionless): 0.998983
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999939
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003615
 - xrf in component IKr (dimensionless): 0.000015
 - xrs in component IKr (dimensionless): 0.001034
 - xs1 in component IKs (dimensionless): 0.005913
 - xs2 in component IKs (dimensionless): 0.000310
 - xk1 in component IK1 (dimensionless): 0.997003
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
03:59:27 (26894): called boinc_finish(0)

</stderr_txt>
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