𝕏

Task 55831124

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_687_0
Workunit 26513691
Created 2 Jul 2024, 14:35:50 UTC
Sent 3 Jul 2024, 5:22:12 UTC
Report deadline 6 Jul 2024, 5:22:12 UTC
Received 3 Jul 2024, 17:40:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224057
Run time 2 hours 0 min
CPU time 1 hours 58 min 54 sec
Validate state Valid
Credit 42.01
Device peak FLOPS 3.39 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.72 MB
Peak swap size 5.33 MB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_687.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_687_0_r1103478709_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_687_0_r1103478709_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.029078
     * GNaL_b in INaL: 0.005496
     * Gto_b in Ito: 0.084485
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031520
     * GKs_b in IKs: 0.001956
     * GK1_b in IK1: 0.167842
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.104399
     * GKb_b in IKb: 0.003819
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037380
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 5643401, states[0] = -94.868913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14052557, states[0] = 17.352794, states[40]= 0.003437
Saving checkpoint... 
Iteration: 19836132, states[0] = -94.780901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28078839, states[0] = 7.356392, states[40]= 0.004418
Saving checkpoint... 
Iteration: 36229777, states[0] = -94.384878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44356304, states[0] = -94.627568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52572014, states[0] = -94.713884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60590798, states[0] = -94.711158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66187046, states[0] = -91.166024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74397398, states[0] = -94.643540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82648215, states[0] = -94.707357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91007028, states[0] = 27.173348, states[40]= 0.130127
Saving checkpoint... 
Iteration: 99372726, states[0] = -94.618261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107708725, states[0] = -94.704820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115916994, states[0] = -94.702572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124236363, states[0] = -94.362887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132426094, states[0] = -94.651165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140751222, states[0] = -94.702446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148975323, states[0] = -94.698845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157384631, states[0] = -94.623144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165682273, states[0] = -94.700104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173836253, states[0] = -94.700792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182148001, states[0] = -44.592763, states[40]= 0.000210
Saving checkpoint... 
Iteration: 190465774, states[0] = -94.666589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198722019, states[0] = -94.700422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206959363, states[0] = -94.697832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215246982, states[0] = -94.393692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223375121, states[0] = -94.614184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231705346, states[0] = -94.699780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240038720, states[0] = 22.852075, states[40]= 0.002119
Saving checkpoint... 
Iteration: 248368162, states[0] = -94.607886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256565537, states[0] = -94.689684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264945004, states[0] = -94.697787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273323217, states[0] = -94.556307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281582963, states[0] = -94.691849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289931252, states[0] = -94.698019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298265074, states[0] = -94.443904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306478484, states[0] = -94.670242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314798449, states[0] = -94.700081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323084042, states[0] = 5.905520, states[40]= 0.004575
Saving checkpoint... 
Iteration: 331278559, states[0] = -94.476075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339617792, states[0] = -94.695145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347953254, states[0] = -94.697378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356218916, states[0] = -94.297007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364493188, states[0] = -94.674580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372874000, states[0] = -94.699000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381068018, states[0] = 13.044351, states[40]= 0.003934
Saving checkpoint... 
Iteration: 389443291, states[0] = -94.656559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397772802, states[0] = -94.700002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406123463, states[0] = -23.208044, states[40]= 0.001354
Saving checkpoint... 
Iteration: 414333192, states[0] = -94.569461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422718918, states[0] = -94.699530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431057970, states[0] = 16.795188, states[40]= 0.003293
Saving checkpoint... 
Iteration: 439253490, states[0] = -94.412229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447595799, states[0] = -94.692923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455555809, states[0] = -94.687791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463768780, states[0] = -94.699881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472090558, states[0] = 2.449237, states[40]= 0.004565
Saving checkpoint... 
Iteration: 480536582, states[0] = -94.684453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488650303, states[0] = -94.697056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497128996, states[0] = -27.907160, states[40]= 0.001271
Saving checkpoint... 
Iteration: 505476167, states[0] = -94.669100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513696539, states[0] = -94.698869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521959719, states[0] = -94.696905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530363176, states[0] = -94.602600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538549128, states[0] = -94.686567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546912394, states[0] = -94.697931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555258853, states[0] = -94.426993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563259893, states[0] = -94.429793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571212490, states[0] = -94.270463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579501520, states[0] = -94.676459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587580405, states[0] = -94.690946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595949287, states[0] = -94.697018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604106460, states[0] = -8.454521, states[40]= 0.002874
Saving checkpoint... 
Iteration: 612441510, states[0] = -94.655348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620719583, states[0] = -94.699187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629021171, states[0] = 26.534111, states[40]= 0.002584
Saving checkpoint... 
Iteration: 637243524, states[0] = -94.381937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645546058, states[0] = -94.685858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653863208, states[0] = -94.698679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662221982, states[0] = -94.307983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670390797, states[0] = -94.625582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678852579, states[0] = -94.698804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687159132, states[0] = -55.049885, states[40]= 0.000042
Saving checkpoint... 
Iteration: 695385139, states[0] = -94.621263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703752162, states[0] = -94.699399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712151796, states[0] = -48.067900, states[40]= 0.000127
Saving checkpoint... 
Iteration: 720427116, states[0] = -94.648110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728533021, states[0] = -94.683329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736926712, states[0] = -94.697280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745106978, states[0] = -8.883092, states[40]= 0.002779
Saving checkpoint... 
Iteration: 753367742, states[0] = -94.606477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761709135, states[0] = -94.698733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769639482, states[0] = -94.695919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777831372, states[0] = -94.698921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786051832, states[0] = 18.871505, states[40]= 0.002881
Saving checkpoint... 
Iteration: 794308903, states[0] = -94.533469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802507199, states[0] = -94.677508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810904820, states[0] = -94.697617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819250010, states[0] = -94.401400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827576115, states[0] = -94.689984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835859203, states[0] = -94.698419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844271623, states[0] = -94.459095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852449761, states[0] = -94.658552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860745583, states[0] = -94.699075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869002364, states[0] = 41.546622, states[40]= 0.439581
Saving checkpoint... 
Iteration: 877329949, states[0] = -94.564393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885508110, states[0] = -94.677585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893870731, states[0] = -94.698121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899540904, states[0] = -94.684498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907795972, states[0] = -94.699014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916074369, states[0] = 10.408811, states[40]= 0.004265
Saving checkpoint... 
Iteration: 924407270, states[0] = -94.636343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932652489, states[0] = -94.696380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940866468, states[0] = -94.698111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949247799, states[0] = -94.394548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957476250, states[0] = -94.668317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965754096, states[0] = -94.698941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974132885, states[0] = -31.218962, states[40]= 0.001040
Saving checkpoint... 
Iteration: 982561787, states[0] = -94.687750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990727035, states[0] = -94.698641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996518125, states[0] = -94.679739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004908221, states[0] = -94.697199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013206203, states[0] = -94.232423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021566106, states[0] = -94.688300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030005886, states[0] = 28.172147, states[40]= 0.188824
Saving checkpoint... 
Iteration: 1038390777, states[0] = -94.624906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046565513, states[0] = -94.688172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055040224, states[0] = 22.431108, states[40]= 0.002193
Saving checkpoint... 
Iteration: 1063308312, states[0] = -94.532013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071615861, states[0] = -94.693667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077552137, states[0] = -94.686095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085975726, states[0] = -94.695509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094282601, states[0] = -94.483519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102689482, states[0] = -94.697610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111054978, states[0] = 17.825599, states[40]= 0.003091
Saving checkpoint... 
Iteration: 1119347848, states[0] = -94.585715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127756635, states[0] = -94.698663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136263688, states[0] = -94.438784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144605117, states[0] = -94.692591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152924867, states[0] = -94.696577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158726564, states[0] = -94.698334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167029217, states[0] = 25.214437, states[40]= 0.001807
Saving checkpoint... 
Iteration: 1175186383, states[0] = -89.239283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183574439, states[0] = -94.689133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191946917, states[0] = -94.696007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200143833, states[0] = -40.761805, states[40]= 0.000357
Saving checkpoint... 
Iteration: 1205999796, states[0] = -94.694699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214340695, states[0] = -94.577307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222574330, states[0] = -94.689049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231043052, states[0] = 21.609007, states[40]= 0.002342
Saving checkpoint... 
Iteration: 1239421566, states[0] = -94.644201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247888153, states[0] = -94.697168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256500532, states[0] = -94.674987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265006904, states[0] = 27.284970, states[40]= 0.135224
Saving checkpoint... 
Iteration: 1273682714, states[0] = -94.697083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282157396, states[0] = -53.376500, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1290509980, states[0] = -94.677316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299098231, states[0] = -2.271716, states[40]= 0.004118
Saving checkpoint... 
Iteration: 1307553866, states[0] = -94.685960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315760130, states[0] = -94.698339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324040715, states[0] = 22.290874, states[40]= 0.002218
Saving checkpoint... 
Iteration: 1332481801, states[0] = -94.669439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340772949, states[0] = -94.698312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349246376, states[0] = -94.389491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357647953, states[0] = -94.695371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365997385, states[0] = -94.694473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374377269, states[0] = -94.613704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382598743, states[0] = -94.691549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390439909, states[0] = -94.653216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397844966, states[0] = -94.697631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405366243, states[0] = -94.603922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413640327, states[0] = -94.694819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421837059, states[0] = -94.697697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429855406, states[0] = -94.697417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437928625, states[0] = -94.695984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446113330, states[0] = -14.369107, states[40]= 0.001755
Saving checkpoint... 
Iteration: 1454267462, states[0] = -94.447813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462455368, states[0] = -94.659774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470693580, states[0] = -94.697074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478971404, states[0] = -94.694911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487234138, states[0] = -94.349685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495424360, states[0] = -94.645260, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.570105
 - CaMKt in component CaMK (millimolar): 0.004188
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.490269
 - nass in component intracellular_ions (millimolar): 6.490355
 - ki in component intracellular_ions (millimolar): 145.422838
 - kss in component intracellular_ions (millimolar): 145.422822
 - cansr in component intracellular_ions (millimolar): 1.587587
 - cajsr in component intracellular_ions (millimolar): 1.586889
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003742
 - hf in component INa (dimensionless): 0.874123
 - hs in component INa (dimensionless): 0.874124
 - j in component INa (dimensionless): 0.874130
 - hsp in component INa (dimensionless): 0.714882
 - jp in component INa (dimensionless): 0.874133
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.720186
 - hLp in component INaL (dimensionless): 0.512482
 - a in component Ito (dimensionless): 0.000638
 - iF in component Ito (dimensionless): 0.999862
 - iS in component Ito (dimensionless): 0.892342
 - ap in component Ito (dimensionless): 0.000325
 - iFp in component Ito (dimensionless): 0.999862
 - iSp in component Ito (dimensionless): 0.932134
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975789
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002697
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.097109
 - xs1 in component IKs (dimensionless): 0.124346
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997423
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:40:01 (18832): called boinc_finish(0)

</stderr_txt>
]]>


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