𝕏

Task 55831121

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_487_1
Workunit 26513689
Created 2 Jul 2024, 14:35:50 UTC
Sent 3 Jul 2024, 5:22:12 UTC
Report deadline 6 Jul 2024, 5:22:12 UTC
Received 3 Jul 2024, 16:19:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224057
Run time 2 hours 0 min 3 sec
CPU time 1 hours 58 min 49 sec
Validate state Valid
Credit 42.59
Device peak FLOPS 3.39 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.72 MB
Peak swap size 5.35 MB
Peak disk usage 0.63 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_487.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_487_1_r109228284_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_487_1_r109228284_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.870939
     * GNaL_b in INaL: 0.005454
     * Gto_b in Ito: 0.085814
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031415
     * GKs_b in IKs: 0.001928
     * GK1_b in IK1: 0.160732
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.203664
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035678
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 5674413, states[0] = -94.841492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 13986016, states[0] = -94.773657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22099781, states[0] = -5.203362, states[40]= 0.003463
Saving checkpoint... 
Iteration: 30425705, states[0] = -94.659960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38624316, states[0] = -94.694092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46877565, states[0] = -94.687729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55233483, states[0] = -94.314125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63547928, states[0] = -94.662376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71738583, states[0] = -94.672389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79918360, states[0] = -94.667488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88129450, states[0] = -28.234127, states[40]= 0.001241
Saving checkpoint... 
Iteration: 95443763, states[0] = -94.619948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103744285, states[0] = -94.663749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111975716, states[0] = -94.659154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120149231, states[0] = -45.223668, states[40]= 0.000191
Saving checkpoint... 
Iteration: 128305308, states[0] = -94.479889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136629223, states[0] = -94.655894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144944456, states[0] = -94.656965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153066524, states[0] = 13.747004, states[40]= 0.003780
Saving checkpoint... 
Iteration: 161457399, states[0] = -94.619479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169693957, states[0] = -94.657576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175320149, states[0] = -94.502186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183715948, states[0] = -94.657753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192030475, states[0] = 24.951665, states[40]= 0.001789
Saving checkpoint... 
Iteration: 200390095, states[0] = -94.579649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208588596, states[0] = -94.649725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216999323, states[0] = -94.653652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225237928, states[0] = -94.304141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233469800, states[0] = -94.623080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241804807, states[0] = -94.657404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250338867, states[0] = -94.527583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258784986, states[0] = -94.657436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267216771, states[0] = -94.223936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275598539, states[0] = -94.650388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284153471, states[0] = -48.876949, states[40]= 0.000111
Saving checkpoint... 
Iteration: 292619484, states[0] = -94.652302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299155627, states[0] = -50.887207, states[40]= 0.000081
Saving checkpoint... 
Iteration: 307274778, states[0] = -94.412153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315569629, states[0] = -94.646717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323800458, states[0] = -94.657148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332161519, states[0] = -56.453472, states[40]= 0.000033
Saving checkpoint... 
Iteration: 340513478, states[0] = -94.635987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348810088, states[0] = -94.657014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356775899, states[0] = -94.657188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364618646, states[0] = -94.652067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372869565, states[0] = -94.656114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381253879, states[0] = -94.355167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389514258, states[0] = -94.636082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397676040, states[0] = -94.655466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405918059, states[0] = -94.655039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414296608, states[0] = -94.459814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422624267, states[0] = -94.652416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431005609, states[0] = 28.303975, states[40]= 0.206086
Saving checkpoint... 
Iteration: 439226368, states[0] = -94.261743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447867012, states[0] = -94.656022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456156611, states[0] = -51.806640, states[40]= 0.000070
Saving checkpoint... 
Iteration: 464415132, states[0] = -94.596083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472800895, states[0] = -94.656860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481145587, states[0] = -41.669231, states[40]= 0.000314
Saving checkpoint... 
Iteration: 489395644, states[0] = -94.582866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497717084, states[0] = -94.656466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506038752, states[0] = 22.891356, states[40]= 0.002080
Saving checkpoint... 
Iteration: 514295533, states[0] = -94.457515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522580005, states[0] = -94.647724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530958635, states[0] = -94.653833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539361096, states[0] = -94.552501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547606400, states[0] = -94.650627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556021186, states[0] = 26.507567, states[40]= 0.002550
Saving checkpoint... 
Iteration: 564241291, states[0] = -94.314739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572467979, states[0] = -94.621591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580916401, states[0] = -94.654761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589295969, states[0] = -94.458240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597610984, states[0] = -94.650969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603266648, states[0] = -94.390865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611895171, states[0] = -94.655173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619439767, states[0] = -94.609358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627644256, states[0] = -94.653449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635854558, states[0] = -94.655902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643926743, states[0] = -94.654409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652155807, states[0] = -51.052388, states[40]= 0.000079
Saving checkpoint... 
Iteration: 660327984, states[0] = -94.512001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666625287, states[0] = -94.652057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674746897, states[0] = -94.656530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683001805, states[0] = 45.512572, states[40]= 0.375942
Saving checkpoint... 
Iteration: 691154929, states[0] = -50.231177, states[40]= 0.000090
Saving checkpoint... 
Iteration: 699563644, states[0] = -94.645127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707973760, states[0] = -94.653130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716406864, states[0] = -94.590335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724642873, states[0] = -94.653189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732907395, states[0] = -94.654691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741135707, states[0] = -33.047221, states[40]= 0.000884
Saving checkpoint... 
Iteration: 749389590, states[0] = -94.577788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757804708, states[0] = -94.656319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766080018, states[0] = 8.065140, states[40]= 0.004427
Saving checkpoint... 
Iteration: 774257208, states[0] = -94.364296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782486289, states[0] = -94.627557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790784546, states[0] = -94.656381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798870929, states[0] = -94.655320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807058289, states[0] = 16.795003, states[40]= 0.003255
Saving checkpoint... 
Iteration: 815309705, states[0] = -94.483101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823508994, states[0] = -94.633982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831657437, states[0] = -94.653833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840004283, states[0] = 31.175363, states[40]= 0.311930
Saving checkpoint... 
Iteration: 848253240, states[0] = -94.352387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856467941, states[0] = -94.621067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864790779, states[0] = -94.656221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873154322, states[0] = -49.664297, states[40]= 0.000098
Saving checkpoint... 
Iteration: 881360944, states[0] = -94.551728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889630720, states[0] = -94.652068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897833049, states[0] = -94.655757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905937662, states[0] = -94.653679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914259610, states[0] = -94.370954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922654784, states[0] = -94.653529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930951152, states[0] = -94.653303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939224967, states[0] = -94.255522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947528612, states[0] = -94.638356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955751207, states[0] = -94.656055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964003021, states[0] = 36.803638, states[40]= 0.425312
Saving checkpoint... 
Iteration: 972365071, states[0] = -94.555737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980677053, states[0] = -94.654459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988781172, states[0] = -94.656037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997172347, states[0] = -67.516156, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1005472309, states[0] = -94.622413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013700926, states[0] = -94.655178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022094174, states[0] = 0.641589, states[40]= 0.004424
Saving checkpoint... 
Iteration: 1030408153, states[0] = -94.590623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038768854, states[0] = -94.655962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047020534, states[0] = 26.571133, states[40]= 0.002797
Saving checkpoint... 
Iteration: 1054989890, states[0] = -94.652087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063262290, states[0] = -94.378209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071635812, states[0] = -94.652102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079837431, states[0] = -94.655370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088103178, states[0] = -5.414735, states[40]= 0.003518
Saving checkpoint... 
Iteration: 1096484995, states[0] = -94.626580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104627111, states[0] = -94.651413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113016186, states[0] = 26.788220, states[40]= 0.007170
Saving checkpoint... 
Iteration: 1121401463, states[0] = -94.585919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129724078, states[0] = -94.655454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137974129, states[0] = -94.652349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146300492, states[0] = -94.465946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154440995, states[0] = -94.608996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162688636, states[0] = -94.654549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171110297, states[0] = -11.201718, states[40]= 0.002276
Saving checkpoint... 
Iteration: 1179439804, states[0] = -94.608371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187670415, states[0] = -94.653814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196060129, states[0] = 16.147698, states[40]= 0.003377
Saving checkpoint... 
Iteration: 1204176004, states[0] = -71.913149, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1212401995, states[0] = -94.586127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220715635, states[0] = -94.655142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228959450, states[0] = -94.652561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237200021, states[0] = -93.941692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245554733, states[0] = -94.642739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253779550, states[0] = -94.655566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262155446, states[0] = -50.713008, states[40]= 0.000084
Saving checkpoint... 
Iteration: 1270551697, states[0] = -94.642185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279015795, states[0] = 26.788755, states[40]= 0.007983
Saving checkpoint... 
Iteration: 1287263383, states[0] = -94.380814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295545545, states[0] = -94.641061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303924439, states[0] = -94.653280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312037519, states[0] = 23.226644, states[40]= 0.002025
Saving checkpoint... 
Iteration: 1320423901, states[0] = -94.599730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328673296, states[0] = -94.653684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336892360, states[0] = -94.653932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345012907, states[0] = 26.696378, states[40]= 0.018930
Saving checkpoint... 
Iteration: 1353334056, states[0] = -94.519156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361746083, states[0] = -94.655293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369827586, states[0] = -94.654982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378060262, states[0] = 16.100438, states[40]= 0.003386
Saving checkpoint... 
Iteration: 1386290093, states[0] = -94.444860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394592028, states[0] = -94.647607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402854211, states[0] = -94.654533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411206801, states[0] = -94.154151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419641276, states[0] = -94.651842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427924160, states[0] = -94.653064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436183354, states[0] = -82.484358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444524880, states[0] = -94.636655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452792021, states[0] = -94.655160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461001747, states[0] = 45.928199, states[40]= 0.364331
Saving checkpoint... 
Iteration: 1469405802, states[0] = -94.588271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477809493, states[0] = -94.654987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486091301, states[0] = 2.311863, states[40]= 0.004524
Saving checkpoint... 
Iteration: 1494384434, states[0] = -94.572307, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.526960
 - CaMKt in component CaMK (millimolar): 0.004175
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.475548
 - nass in component intracellular_ions (millimolar): 6.475633
 - ki in component intracellular_ions (millimolar): 145.438560
 - kss in component intracellular_ions (millimolar): 145.438545
 - cansr in component intracellular_ions (millimolar): 1.582749
 - cajsr in component intracellular_ions (millimolar): 1.582073
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003758
 - hf in component INa (dimensionless): 0.873341
 - hs in component INa (dimensionless): 0.873342
 - j in component INa (dimensionless): 0.873348
 - hsp in component INa (dimensionless): 0.713435
 - jp in component INa (dimensionless): 0.873351
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.719023
 - hLp in component INaL (dimensionless): 0.510859
 - a in component Ito (dimensionless): 0.000639
 - iF in component Ito (dimensionless): 0.999861
 - iS in component Ito (dimensionless): 0.891834
 - ap in component Ito (dimensionless): 0.000326
 - iFp in component Ito (dimensionless): 0.999861
 - iSp in component Ito (dimensionless): 0.931638
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975650
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002662
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.097720
 - xs1 in component IKs (dimensionless): 0.124958
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997434
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:18:22 (23464): called boinc_finish(0)

</stderr_txt>
]]>


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