𝕏

Task 55831119

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_387_1
Workunit 26513688
Created 2 Jul 2024, 14:35:50 UTC
Sent 3 Jul 2024, 5:22:12 UTC
Report deadline 6 Jul 2024, 5:22:12 UTC
Received 3 Jul 2024, 16:19:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224057
Run time 2 hours 0 min 3 sec
CPU time 1 hours 58 min 47 sec
Validate state Valid
Credit 44.08
Device peak FLOPS 3.39 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.72 MB
Peak swap size 5.34 MB
Peak disk usage 0.63 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_387.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_387_1_r30766390_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_387_1_r30766390_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.888124
     * GNaL_b in INaL: 0.006064
     * Gto_b in Ito: 0.084245
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032118
     * GKs_b in IKs: 0.001948
     * GK1_b in IK1: 0.166060
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.779885
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035127
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 5742355, states[0] = -94.856324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14014096, states[0] = 26.447628, states[40]= 0.013209
Saving checkpoint... 
Iteration: 22168506, states[0] = -70.421835, states[40]= 0.000003
Saving checkpoint... 
Iteration: 30539938, states[0] = -94.716698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38970845, states[0] = -94.714361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47287329, states[0] = -94.499806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55511802, states[0] = -94.680472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63828071, states[0] = -94.696317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72045201, states[0] = 21.051335, states[40]= 0.002278
Saving checkpoint... 
Iteration: 78964199, states[0] = -94.687594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87472869, states[0] = -94.655900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95831353, states[0] = -94.686086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104186792, states[0] = -89.289027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112765843, states[0] = -94.683901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121158098, states[0] = -53.532845, states[40]= 0.000054
Saving checkpoint... 
Iteration: 127541325, states[0] = -94.667675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135796419, states[0] = -94.681731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144034989, states[0] = 24.083646, states[40]= 0.001820
Saving checkpoint... 
Iteration: 152104922, states[0] = -6.567018, states[40]= 0.003266
Saving checkpoint... 
Iteration: 160422018, states[0] = -94.625540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168771613, states[0] = -94.680356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177059814, states[0] = 16.433807, states[40]= 0.003262
Saving checkpoint... 
Iteration: 185098365, states[0] = -1.797502, states[40]= 0.004144
Saving checkpoint... 
Iteration: 192952597, states[0] = -94.677016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201202206, states[0] = -94.133789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209640948, states[0] = -94.676285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217890846, states[0] = -94.678106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226054282, states[0] = 18.343685, states[40]= 0.002890
Saving checkpoint... 
Iteration: 234246664, states[0] = -94.364697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242490233, states[0] = -94.652593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250657644, states[0] = -94.676927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259126286, states[0] = -24.815904, states[40]= 0.001360
Saving checkpoint... 
Iteration: 267419336, states[0] = -94.622662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275636769, states[0] = -94.675621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283908512, states[0] = -94.677392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292131982, states[0] = -29.641773, states[40]= 0.001166
Saving checkpoint... 
Iteration: 300525336, states[0] = -94.661257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308658889, states[0] = -94.676795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317028046, states[0] = 25.696104, states[40]= 0.001678
Saving checkpoint... 
Iteration: 325452548, states[0] = -94.638909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333749354, states[0] = -94.679012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341958743, states[0] = -94.676081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350302277, states[0] = -94.498159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358580438, states[0] = -94.670213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366816790, states[0] = -94.678746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375119478, states[0] = -18.973019, states[40]= 0.001363
Saving checkpoint... 
Iteration: 383539712, states[0] = -94.663941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391744280, states[0] = -94.678861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399944491, states[0] = -94.676312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408228344, states[0] = -94.302451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416496090, states[0] = -94.653829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424872031, states[0] = -94.677822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430643114, states[0] = -94.675681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439288588, states[0] = -94.471645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446898667, states[0] = -94.677257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455278207, states[0] = -94.449038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463643020, states[0] = -94.675614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471855826, states[0] = -94.678017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480282699, states[0] = -94.459055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488422256, states[0] = -94.623838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494637524, states[0] = -94.675211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502838076, states[0] = -94.678230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511138832, states[0] = -35.522817, states[40]= 0.000686
Saving checkpoint... 
Iteration: 519293955, states[0] = -94.482264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527685622, states[0] = -94.677465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536144130, states[0] = -40.193242, states[40]= 0.000386
Saving checkpoint... 
Iteration: 544497395, states[0] = -94.653956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552793376, states[0] = -94.678591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561183622, states[0] = -84.354412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569413374, states[0] = -94.618511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577744987, states[0] = -94.678521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586120087, states[0] = -19.502418, states[40]= 0.001349
Saving checkpoint... 
Iteration: 594520933, states[0] = -94.659728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602868226, states[0] = -94.677563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611147136, states[0] = -42.914349, states[40]= 0.000267
Saving checkpoint... 
Iteration: 619408829, states[0] = -94.615598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627653525, states[0] = -94.675910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635917182, states[0] = -94.676508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643972465, states[0] = -94.675174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652209548, states[0] = -94.223645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660397213, states[0] = -94.607741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668538149, states[0] = -94.663121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676961298, states[0] = -94.675392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685218428, states[0] = -94.264745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693481484, states[0] = -94.648917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701615306, states[0] = -94.673172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710028088, states[0] = 25.688185, states[40]= 0.001678
Saving checkpoint... 
Iteration: 718455531, states[0] = -94.639411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726785515, states[0] = -94.678309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734858117, states[0] = -94.677495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742995557, states[0] = -94.674404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751393404, states[0] = -94.604830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759594430, states[0] = -94.671076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767935059, states[0] = -94.675856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776351555, states[0] = -94.567045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784686596, states[0] = -94.677024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792972202, states[0] = -94.674907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801402057, states[0] = -94.610830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809676017, states[0] = -94.676602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818024262, states[0] = 26.361343, states[40]= 0.001841
Saving checkpoint... 
Iteration: 826381800, states[0] = -94.595696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834813036, states[0] = -94.677919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843082700, states[0] = 6.988532, states[40]= 0.004458
Saving checkpoint... 
Iteration: 851340107, states[0] = -94.553622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859650244, states[0] = -94.675305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867851293, states[0] = -94.677362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876271095, states[0] = -94.431352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884488919, states[0] = -94.650880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892646561, states[0] = -94.675036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900799927, states[0] = -94.677909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909151211, states[0] = -46.693449, states[40]= 0.000156
Saving checkpoint... 
Iteration: 917380974, states[0] = -94.594849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925761578, states[0] = -94.677964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934078421, states[0] = 8.991266, states[40]= 0.004318
Saving checkpoint... 
Iteration: 942480515, states[0] = -94.648145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950719483, states[0] = -94.677525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959059128, states[0] = 16.689735, states[40]= 0.003218
Saving checkpoint... 
Iteration: 967253014, states[0] = -94.382398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975576490, states[0] = -94.668574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983924287, states[0] = -94.675708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992191336, states[0] = -92.417657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000292661, states[0] = -94.478829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008543864, states[0] = -94.663544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016720524, states[0] = -94.677422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024898803, states[0] = -94.676190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033044893, states[0] = 21.323037, states[40]= 0.002300
Saving checkpoint... 
Iteration: 1041294591, states[0] = -94.482533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049612368, states[0] = -94.672280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057784798, states[0] = -94.677703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066110848, states[0] = -11.402446, states[40]= 0.002234
Saving checkpoint... 
Iteration: 1074348895, states[0] = -94.563539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082664742, states[0] = -94.675626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090739238, states[0] = -94.677529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098994447, states[0] = -94.673778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107222662, states[0] = -94.280214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115372922, states[0] = -94.587576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123622240, states[0] = -94.672961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131834319, states[0] = -94.677125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140063495, states[0] = 15.111868, states[40]= 0.003509
Saving checkpoint... 
Iteration: 1148223268, states[0] = -94.282411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156496103, states[0] = -94.652469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164743567, states[0] = -94.677431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172976616, states[0] = -94.674097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181257572, states[0] = -94.395122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189594422, states[0] = -94.670285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197550898, states[0] = -94.664408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205851676, states[0] = -94.676734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214030801, states[0] = 25.114397, states[40]= 0.001703
Saving checkpoint... 
Iteration: 1222255893, states[0] = -94.390278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230609932, states[0] = -94.671731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238996312, states[0] = -94.673473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247274163, states[0] = -94.438102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255529185, states[0] = -94.660277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263890662, states[0] = -94.675918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272058522, states[0] = 16.902327, states[40]= 0.003178
Saving checkpoint... 
Iteration: 1280375155, states[0] = -94.589241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288721430, states[0] = -94.676936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297068214, states[0] = 13.305562, states[40]= 0.003805
Saving checkpoint... 
Iteration: 1305331479, states[0] = -94.541730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313754858, states[0] = -94.677227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322018934, states[0] = 26.949318, states[40]= 0.003606
Saving checkpoint... 
Iteration: 1328162339, states[0] = -57.419279, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1336304132, states[0] = -94.499618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344868259, states[0] = -94.676198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353080541, states[0] = 8.015340, states[40]= 0.004395
Saving checkpoint... 
Iteration: 1361382106, states[0] = -94.594959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369824587, states[0] = -94.676810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378121534, states[0] = -20.753521, states[40]= 0.001336
Saving checkpoint... 
Iteration: 1386486799, states[0] = -94.649313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394784971, states[0] = -94.677083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403167357, states[0] = -62.540560, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1411445271, states[0] = -94.633718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419913522, states[0] = -94.675148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425541869, states[0] = -94.662418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433682968, states[0] = -94.675709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442043119, states[0] = 21.852252, states[40]= 0.002202
Saving checkpoint... 
Iteration: 1450221781, states[0] = -94.276245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458448012, states[0] = -94.634853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466657974, states[0] = -94.674597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474978112, states[0] = -94.673504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483166857, states[0] = -62.013753, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1491495699, states[0] = -94.651739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499675975, states[0] = -94.675332, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.548835
 - CaMKt in component CaMK (millimolar): 0.004190
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.482816
 - nass in component intracellular_ions (millimolar): 6.482902
 - ki in component intracellular_ions (millimolar): 145.430212
 - kss in component intracellular_ions (millimolar): 145.430197
 - cansr in component intracellular_ions (millimolar): 1.586134
 - cajsr in component intracellular_ions (millimolar): 1.585441
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003750
 - hf in component INa (dimensionless): 0.873738
 - hs in component INa (dimensionless): 0.873739
 - j in component INa (dimensionless): 0.873745
 - hsp in component INa (dimensionless): 0.714169
 - jp in component INa (dimensionless): 0.873748
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.719613
 - hLp in component INaL (dimensionless): 0.511693
 - a in component Ito (dimensionless): 0.000638
 - iF in component Ito (dimensionless): 0.999861
 - iS in component Ito (dimensionless): 0.892011
 - ap in component Ito (dimensionless): 0.000325
 - iFp in component Ito (dimensionless): 0.999861
 - iSp in component Ito (dimensionless): 0.931804
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975446
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002685
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.097520
 - xs1 in component IKs (dimensionless): 0.125392
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997428
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:42:00 (20200): called boinc_finish(0)

</stderr_txt>
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