𝕏

Task 55829536

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_ENDO_6000-conf_885_0
Workunit 26512897
Created 2 Jul 2024, 14:35:07 UTC
Sent 3 Jul 2024, 5:07:02 UTC
Report deadline 6 Jul 2024, 5:07:02 UTC
Received 3 Jul 2024, 17:08:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230398
Run time 2 hours 6 min 35 sec
CPU time 2 hours 5 min 24 sec
Validate state Valid
Credit 46.05
Device peak FLOPS 3.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.79 MB
Peak swap size 4.10 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_ENDO_6000-conf_885.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_ENDO_6000-conf_885_0_r582384107_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_ENDO_6000-conf_885_0_r582384107_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.702568
     * GNaL_b in INaL: 0.006049
     * Gto_b in Ito: 0.083160
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031564
     * GKs_b in IKs: 0.001950
     * GK1_b in IK1: 0.162375
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.934539
     * GKb_b in IKb: 0.003815
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031797
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12085518, states[0] = 11.294761, states[40]= 0.003580
Saving checkpoint... 
Iteration: 24081372, states[0] = 13.375199, states[40]= 0.002319
Saving checkpoint... 
Iteration: 36167397, states[0] = -42.904750, states[40]= 0.000620
Saving checkpoint... 
Iteration: 48205324, states[0] = -74.093959, states[40]= 0.000005
Saving checkpoint... 
Iteration: 60183987, states[0] = -54.714907, states[40]= 0.000123
Saving checkpoint... 
Iteration: 72209043, states[0] = -77.615088, states[40]= 0.000003
Saving checkpoint... 
Iteration: 84276649, states[0] = -93.499540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96332321, states[0] = -93.675381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108322123, states[0] = -93.649165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120265458, states[0] = -93.449664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132326215, states[0] = -93.659127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144341935, states[0] = -93.695882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156383199, states[0] = -93.769302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168442473, states[0] = -93.834557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180403330, states[0] = -93.795583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192479300, states[0] = -93.859929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204481515, states[0] = -93.861149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216425677, states[0] = -93.819394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228468227, states[0] = -93.853045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240513304, states[0] = -93.876595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252621638, states[0] = -93.904307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264643813, states[0] = -93.906950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276801594, states[0] = -93.912527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288824547, states[0] = -93.912215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301002599, states[0] = -93.906794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313174287, states[0] = -93.900284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325216723, states[0] = -93.898741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337336541, states[0] = -93.894732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349330707, states[0] = -93.894895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361300697, states[0] = -93.895835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373312460, states[0] = -93.895435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385388022, states[0] = -93.893088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397427637, states[0] = -93.891924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409567862, states[0] = -93.888255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421563812, states[0] = -93.888333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433554073, states[0] = -93.888549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445561451, states[0] = -93.888350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457590387, states[0] = -93.887645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469607923, states[0] = -93.887221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481657978, states[0] = -93.886091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493700165, states[0] = -93.885186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505721594, states[0] = -93.884732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517826641, states[0] = -93.882736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529853419, states[0] = -93.882250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541869437, states[0] = -93.881957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553960039, states[0] = -93.880485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566037538, states[0] = -93.879332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578060243, states[0] = -93.878999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590167223, states[0] = -93.877598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602240760, states[0] = -93.876716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614288022, states[0] = -93.876176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626298491, states[0] = -93.876045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638390466, states[0] = -93.875091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650444743, states[0] = -93.874560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661904882, states[0] = -93.881176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673588185, states[0] = -93.887345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685660270, states[0] = -93.885710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697715172, states[0] = -93.884549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709872138, states[0] = -93.881639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722032869, states[0] = -93.879144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734110846, states[0] = -93.878072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746201033, states[0] = -93.876940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758287055, states[0] = -93.875952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770347838, states[0] = -93.875298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782370127, states[0] = -93.875056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794456672, states[0] = -93.874216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806465269, states[0] = -93.874119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818520837, states[0] = -93.873613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830642262, states[0] = -93.872617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842679343, states[0] = -93.872321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854795756, states[0] = -93.871494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866796324, states[0] = -93.871471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878915850, states[0] = -93.870707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890908065, states[0] = -93.870734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902914268, states[0] = -93.870677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914916267, states[0] = -93.870646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926925440, states[0] = -93.870572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938954215, states[0] = -93.870387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950941240, states[0] = -93.870442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962913055, states[0] = -93.870587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974980416, states[0] = -93.870180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986987930, states[0] = -93.870119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998881250, states[0] = -93.870719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010895029, states[0] = -93.870616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022985640, states[0] = -93.870073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035251170, states[0] = -93.380286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047422698, states[0] = -93.815077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059435656, states[0] = -93.827125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071495516, states[0] = -93.867097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083590197, states[0] = -93.897782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095723733, states[0] = -93.910588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107890437, states[0] = -93.909343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120118335, states[0] = -93.901049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132264770, states[0] = -93.895770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144420919, states[0] = -93.890900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156543150, states[0] = -93.887640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168788317, states[0] = -93.882371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180880177, states[0] = -93.880738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193064143, states[0] = -93.877945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205146464, states[0] = -93.876853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217155259, states[0] = -93.876725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229285153, states[0] = -93.875206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241417129, states[0] = -93.873855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253570798, states[0] = -93.872489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265683864, states[0] = -93.871600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277858696, states[0] = -93.870403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290051308, states[0] = 24.700550, states[40]= 0.000362
Saving checkpoint... 
Iteration: 1302095915, states[0] = 7.341914, states[40]= 0.002957
Saving checkpoint... 
Iteration: 1314249268, states[0] = -93.370095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326400833, states[0] = -93.790553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338514210, states[0] = -93.875161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350689262, states[0] = -93.908747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362870499, states[0] = -93.909482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374956661, states[0] = -93.906735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387074435, states[0] = -93.902286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399153907, states[0] = -93.899265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411344429, states[0] = -93.892739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423592752, states[0] = -93.886019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435723526, states[0] = -93.883181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447817941, states[0] = -93.881378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459906554, states[0] = -93.879851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471933152, states[0] = -93.879407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484078947, states[0] = -93.877272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496208751, states[0] = -93.875629, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.745197
 - CaMKt in component CaMK (millimolar): 0.001323
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.677513
 - nass in component intracellular_ions (millimolar): 6.677637
 - ki in component intracellular_ions (millimolar): 145.186056
 - kss in component intracellular_ions (millimolar): 145.186046
 - cansr in component intracellular_ions (millimolar): 1.836171
 - cajsr in component intracellular_ions (millimolar): 1.836038
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004067
 - hf in component INa (dimensionless): 0.858437
 - hs in component INa (dimensionless): 0.858437
 - j in component INa (dimensionless): 0.858439
 - hsp in component INa (dimensionless): 0.686465
 - jp in component INa (dimensionless): 0.858439
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.697618
 - hLp in component INaL (dimensionless): 0.502028
 - a in component Ito (dimensionless): 0.000674
 - iF in component Ito (dimensionless): 0.999840
 - iS in component Ito (dimensionless): 0.999217
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999840
 - iSp in component Ito (dimensionless): 0.999695
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999514
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005516
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000598
 - xs1 in component IKs (dimensionless): 0.014900
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997625
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:47:10 (68619): called boinc_finish(0)

</stderr_txt>
]]>


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