𝕏

Task 55829071

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_984_1
Workunit 26512664
Created 2 Jul 2024, 14:34:57 UTC
Sent 3 Jul 2024, 5:03:42 UTC
Report deadline 6 Jul 2024, 14:39:42 UTC
Received 3 Jul 2024, 8:35:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214625
Run time 2 hours 36 min 40 sec
CPU time 2 hours 33 min 51 sec
Validate state Valid
Credit 61.59
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.46 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_984.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_984_1_r507824794_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_984_1_r507824794_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.769271
     * GNaL_b in INaL: 0.005626
     * Gto_b in Ito: 0.085147
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031974
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.163849
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.574543
     * GKb_b in IKb: 0.003778
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037319
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13594734, states[0] = -19.198007, states[40]= 0.001007
Saving checkpoint... 
Iteration: 27201037, states[0] = -94.878780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40742863, states[0] = -94.928384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54371355, states[0] = -95.013709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68046247, states[0] = 12.602261, states[40]= 0.005042
Saving checkpoint... 
Iteration: 81537827, states[0] = 15.796238, states[40]= 0.005363
Saving checkpoint... 
Iteration: 95197796, states[0] = -94.825361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108608056, states[0] = -28.153817, states[40]= 0.000545
Saving checkpoint... 
Iteration: 122263118, states[0] = -94.922655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135591523, states[0] = -12.336190, states[40]= 0.001884
Saving checkpoint... 
Iteration: 149099724, states[0] = -20.031756, states[40]= 0.000958
Saving checkpoint... 
Iteration: 162438863, states[0] = -95.012102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176089892, states[0] = -10.800400, states[40]= 0.002170
Saving checkpoint... 
Iteration: 189642466, states[0] = -64.013348, states[40]= 0.000002
Saving checkpoint... 
Iteration: 203229932, states[0] = -94.876512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216822757, states[0] = -94.969163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230307339, states[0] = -94.959051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243709834, states[0] = -94.842242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257357975, states[0] = -94.986996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270953299, states[0] = -95.013920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284383451, states[0] = -94.996647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297914854, states[0] = -95.005783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311546818, states[0] = 12.608820, states[40]= 0.005026
Saving checkpoint... 
Iteration: 325090772, states[0] = -11.557033, states[40]= 0.002025
Saving checkpoint... 
Iteration: 338612485, states[0] = -32.149094, states[40]= 0.000362
Saving checkpoint... 
Iteration: 352219629, states[0] = -94.859468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365237726, states[0] = -94.887713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378733505, states[0] = -94.881551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392174374, states[0] = -94.709637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405360306, states[0] = -94.987839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418962974, states[0] = -95.015413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432504534, states[0] = 29.674605, states[40]= 0.151681
Saving checkpoint... 
Iteration: 446065865, states[0] = 4.673575, states[40]= 0.004686
Saving checkpoint... 
Iteration: 459557388, states[0] = 8.400423, states[40]= 0.004862
Saving checkpoint... 
Iteration: 473022555, states[0] = 20.499054, states[40]= 0.008080
Saving checkpoint... 
Iteration: 486487108, states[0] = -95.018821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500120269, states[0] = -39.757139, states[40]= 0.000131
Saving checkpoint... 
Iteration: 513369634, states[0] = -94.991512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526748465, states[0] = -94.902136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540072522, states[0] = 1.357870, states[40]= 0.004403
Saving checkpoint... 
Iteration: 553579248, states[0] = -2.586177, states[40]= 0.003844
Saving checkpoint... 
Iteration: 567074222, states[0] = 0.429504, states[40]= 0.004294
Saving checkpoint... 
Iteration: 580302169, states[0] = -94.954985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593576443, states[0] = -0.848356, states[40]= 0.004122
Saving checkpoint... 
Iteration: 606992154, states[0] = -95.019373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620594735, states[0] = -15.216910, states[40]= 0.001433
Saving checkpoint... 
Iteration: 634051477, states[0] = 10.797898, states[40]= 0.004944
Saving checkpoint... 
Iteration: 647666567, states[0] = -94.058413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661287492, states[0] = -94.943227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674898379, states[0] = -95.001066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688417162, states[0] = -95.006096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701907226, states[0] = -95.003532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715370875, states[0] = -94.991859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728756765, states[0] = -94.912197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742129259, states[0] = -49.081495, states[40]= 0.000031
Saving checkpoint... 
Iteration: 755335865, states[0] = -94.976071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768758527, states[0] = -94.914225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782362409, states[0] = -94.988475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795901617, states[0] = -95.001923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809481690, states[0] = -95.017912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822780515, states[0] = -94.936919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836059641, states[0] = 7.449319, states[40]= 0.004827
Saving checkpoint... 
Iteration: 849601983, states[0] = -22.112245, states[40]= 0.000835
Saving checkpoint... 
Iteration: 863118915, states[0] = -38.410134, states[40]= 0.000159
Saving checkpoint... 
Iteration: 876492687, states[0] = -95.019269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890020566, states[0] = 20.937193, states[40]= 0.009298
Saving checkpoint... 
Iteration: 903326448, states[0] = -94.970745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916657840, states[0] = -87.452172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930159691, states[0] = -89.914751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943663916, states[0] = -93.207072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957042147, states[0] = 14.366467, states[40]= 0.005160
Saving checkpoint... 
Iteration: 970622457, states[0] = -41.963229, states[40]= 0.000095
Saving checkpoint... 
Iteration: 984104031, states[0] = -24.063638, states[40]= 0.000739
Saving checkpoint... 
Iteration: 997586201, states[0] = -7.636856, states[40]= 0.002829
Saving checkpoint... 
Iteration: 1010877969, states[0] = -94.994275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024386476, states[0] = -94.997163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037918821, states[0] = -95.006281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051398948, states[0] = -95.000996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064570736, states[0] = 2.293187, states[40]= 0.004498
Saving checkpoint... 
Iteration: 1077940505, states[0] = -95.011000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091370677, states[0] = -94.991548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104888948, states[0] = -94.997912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118277871, states[0] = -94.934264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131835233, states[0] = -94.975499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145284172, states[0] = -94.940025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158695626, states[0] = -94.813900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172123961, states[0] = -43.503421, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1185621691, states[0] = -41.186143, states[40]= 0.000106
Saving checkpoint... 
Iteration: 1199126111, states[0] = -45.739688, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1212665722, states[0] = -93.852039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226153101, states[0] = -79.473945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239668128, states[0] = -94.326783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253140045, states[0] = -61.077210, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1266768394, states[0] = -94.924747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280363481, states[0] = -94.988602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293881499, states[0] = -94.995328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307402948, states[0] = -95.001978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320996531, states[0] = -95.019446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334194811, states[0] = -94.812111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347661264, states[0] = -91.502105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361027843, states[0] = 19.133852, states[40]= 0.006452
Saving checkpoint... 
Iteration: 1374516242, states[0] = 21.748633, states[40]= 0.015241
Saving checkpoint... 
Iteration: 1387871798, states[0] = -94.991786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401288215, states[0] = -94.943381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414601322, states[0] = -21.481841, states[40]= 0.000869
Saving checkpoint... 
Iteration: 1427885871, states[0] = -94.996712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441435090, states[0] = -95.009676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455000916, states[0] = 47.313080, states[40]= 0.020666
Saving checkpoint... 
Iteration: 1468545579, states[0] = 13.081011, states[40]= 0.005055
Saving checkpoint... 
Iteration: 1481866863, states[0] = -94.989829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495383791, states[0] = -94.995979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508841712, states[0] = -92.009350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522029619, states[0] = -74.492084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535551100, states[0] = -94.961092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548916987, states[0] = 21.713845, states[40]= 0.015311
Saving checkpoint... 
Iteration: 1562171020, states[0] = -7.034534, states[40]= 0.003334
Saving checkpoint... 
Iteration: 1575555053, states[0] = -95.257182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588775135, states[0] = -95.277514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602212212, states[0] = -95.206216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615494628, states[0] = -95.294128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628905618, states[0] = -95.196827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642412391, states[0] = -95.208523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655826233, states[0] = -72.434573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1669221977, states[0] = 20.026408, states[40]= 0.009628
Saving checkpoint... 
Iteration: 1682622001, states[0] = -95.223663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696097873, states[0] = -95.183836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709637461, states[0] = -95.244223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723011434, states[0] = -52.404212, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1736389873, states[0] = -95.292600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749808894, states[0] = -95.203445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763103729, states[0] = 34.158990, states[40]= 0.124150
Saving checkpoint... 
Iteration: 1776461148, states[0] = -95.098197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789792548, states[0] = -95.294395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803018600, states[0] = 20.847240, states[40]= 0.010370
Saving checkpoint... 
Iteration: 1816271529, states[0] = -94.969150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829572650, states[0] = 0.452331, states[40]= 0.004329
Saving checkpoint... 
Iteration: 1843052721, states[0] = 9.951882, states[40]= 0.004931
Saving checkpoint... 
Iteration: 1856155894, states[0] = -85.979315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869572839, states[0] = 0.937376, states[40]= 0.004364
Saving checkpoint... 
Iteration: 1883114461, states[0] = -34.425497, states[40]= 0.000274
Saving checkpoint... 
Iteration: 1896580167, states[0] = -3.334718, states[40]= 0.003714
Saving checkpoint... 
Iteration: 1909960071, states[0] = -95.016654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923392288, states[0] = -95.000214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936834798, states[0] = -94.975935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950215989, states[0] = -94.852965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963530785, states[0] = 18.255542, states[40]= 0.005989
Saving checkpoint... 
Iteration: 1976730887, states[0] = -94.876928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990135808, states[0] = -56.261697, states[40]= 0.000010
Saving checkpoint... 
Iteration: 2003564730, states[0] = 5.195381, states[40]= 0.004718
Saving checkpoint... 
Iteration: 2016833117, states[0] = -94.973865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030080058, states[0] = -3.119484, states[40]= 0.003750
Saving checkpoint... 
Iteration: 2043567425, states[0] = 3.934103, states[40]= 0.004636
Saving checkpoint... 
Iteration: 2056912211, states[0] = -95.003977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070333487, states[0] = -94.973940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083857198, states[0] = -94.985427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097315954, states[0] = -94.963522, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.895187
 - CaMKt in component CaMK (millimolar): 0.006903
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.578406
 - nass in component intracellular_ions (millimolar): 6.578465
 - ki in component intracellular_ions (millimolar): 145.400347
 - kss in component intracellular_ions (millimolar): 145.400328
 - cansr in component intracellular_ions (millimolar): 1.307031
 - cajsr in component intracellular_ions (millimolar): 1.269213
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003621
 - hf in component INa (dimensionless): 0.879885
 - hs in component INa (dimensionless): 0.879881
 - j in component INa (dimensionless): 0.879852
 - hsp in component INa (dimensionless): 0.725613
 - jp in component INa (dimensionless): 0.879834
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709999
 - hLp in component INaL (dimensionless): 0.452564
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622269
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.697368
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936263
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001582
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329488
 - xs1 in component IKs (dimensionless): 0.239644
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997339
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:54:20 (725): called boinc_finish(0)

</stderr_txt>
]]>


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