𝕏

Task 55828201

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_783_1
Workunit 26512229
Created 2 Jul 2024, 14:34:31 UTC
Sent 3 Jul 2024, 4:58:41 UTC
Report deadline 6 Jul 2024, 4:58:41 UTC
Received 3 Jul 2024, 8:01:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227516
Run time 1 hours 35 min 16 sec
CPU time 1 hours 35 min 16 sec
Validate state Valid
Credit 45.02
Device peak FLOPS 3.77 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.03 MB
Peak swap size 6.22 MB
Peak disk usage 1.24 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_783.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_783_1_r68169686_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_783_1_r68169686_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.878601
     * GNaL_b in INaL: 0.006043
     * Gto_b in Ito: 0.082014
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031693
     * GKs_b in IKs: 0.001937
     * GK1_b in IK1: 0.166227
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.780953
     * GKb_b in IKb: 0.003788
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036641
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7276592, states[0] = -86.832349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17625557, states[0] = -86.745321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28060690, states[0] = 11.391380, states[40]= 0.004298
Saving checkpoint... 
Iteration: 38477917, states[0] = -86.639463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48817092, states[0] = -86.631700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59241189, states[0] = -86.605196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69755938, states[0] = -86.584021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80125301, states[0] = -22.473102, states[40]= 0.000823
Saving checkpoint... 
Iteration: 90657106, states[0] = -86.575503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101227916, states[0] = -86.563705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111854404, states[0] = -86.551537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122238153, states[0] = -86.368141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132607147, states[0] = -86.555295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142957639, states[0] = -86.554470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153371724, states[0] = -86.545675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163757549, states[0] = -86.540062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174229188, states[0] = -86.345451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184720129, states[0] = -86.551483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195041249, states[0] = -86.547290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202713646, states[0] = -86.550406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213024286, states[0] = -86.546805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223472116, states[0] = -86.539265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233937239, states[0] = -86.534772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244350479, states[0] = -86.481238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254907377, states[0] = -86.547904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265529272, states[0] = -86.537837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275960059, states[0] = -86.534043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286310015, states[0] = -86.448455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296565123, states[0] = -86.542384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306915470, states[0] = -86.547380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317351798, states[0] = -86.539827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327782844, states[0] = -86.535051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338317542, states[0] = -86.455234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348678037, states[0] = -86.547982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359074765, states[0] = -86.544405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366202200, states[0] = -86.179306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376687308, states[0] = -86.548140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387080840, states[0] = -86.544265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397440194, states[0] = -86.538491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407904832, states[0] = -86.534057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418697432, states[0] = -86.548289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429139939, states[0] = -86.543162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439600190, states[0] = -86.536610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449995511, states[0] = -86.533466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460333292, states[0] = -86.468245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470650060, states[0] = -86.547127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481134033, states[0] = -86.543253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491544934, states[0] = -86.537192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502029915, states[0] = 20.934260, states[40]= 0.005047
Saving checkpoint... 
Iteration: 512340412, states[0] = -86.473555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522855889, states[0] = -86.548042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533351161, states[0] = -86.539674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543966466, states[0] = -86.533620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554591341, states[0] = -86.544195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565136885, states[0] = -86.543184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575589061, states[0] = -86.536695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586016210, states[0] = 22.268288, states[40]= 0.012701
Saving checkpoint... 
Iteration: 596294719, states[0] = -86.432429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606761175, states[0] = -86.548697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617176503, states[0] = -86.542470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627543493, states[0] = -86.537182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637793784, states[0] = -86.534811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648208008, states[0] = -86.288032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658986388, states[0] = -86.545936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669351201, states[0] = -86.539648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679741117, states[0] = -86.535234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690176199, states[0] = -67.480629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 700473993, states[0] = -86.529062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710833526, states[0] = -86.548262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721186149, states[0] = -86.542282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731613627, states[0] = -86.536412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741969036, states[0] = -86.533568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752284754, states[0] = -86.420959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762646025, states[0] = -86.546931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773070523, states[0] = -86.544363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783856258, states[0] = -86.534313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794282878, states[0] = -86.418687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804684218, states[0] = -86.547973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815042906, states[0] = -86.544868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825378725, states[0] = -86.539226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835713627, states[0] = -86.535444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846088647, states[0] = 3.559380, states[40]= 0.003956
Saving checkpoint... 
Iteration: 856386613, states[0] = -86.500654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866831178, states[0] = -86.548258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877358288, states[0] = -86.539507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887614152, states[0] = -86.536378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898070114, states[0] = 10.501476, states[40]= 0.004226
Saving checkpoint... 
Iteration: 908343160, states[0] = -86.475443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918738313, states[0] = -86.548590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928994209, states[0] = -86.545745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939099829, states[0] = -86.543792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949470906, states[0] = -86.537983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959891679, states[0] = -86.534032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970318511, states[0] = -86.455908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980797513, states[0] = -86.548512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991072375, states[0] = -86.544289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001347907, states[0] = -86.539636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011808867, states[0] = -86.534625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022197835, states[0] = -85.887827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032614916, states[0] = -86.545523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043090182, states[0] = -86.543951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053525379, states[0] = -86.537311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063886946, states[0] = -86.534046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074430699, states[0] = -86.517715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085091677, states[0] = -86.543915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095469082, states[0] = -86.537979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105761807, states[0] = -86.534984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116156088, states[0] = -47.090187, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1126484640, states[0] = -86.531141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133661265, states[0] = -86.535870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144050164, states[0] = 16.322743, states[40]= 0.004229
Saving checkpoint... 
Iteration: 1154526416, states[0] = -86.537814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165028281, states[0] = -86.545076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175430177, states[0] = -86.538463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185686834, states[0] = -86.535622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196048156, states[0] = 16.845055, states[40]= 0.004235
Saving checkpoint... 
Iteration: 1206623517, states[0] = -86.545920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213991750, states[0] = -86.533345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224528371, states[0] = -86.538055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235093380, states[0] = -86.543857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245745483, states[0] = -86.535094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256208271, states[0] = -86.290054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266695638, states[0] = -86.548096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277058665, states[0] = -86.544492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287558478, states[0] = -86.536896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298105746, states[0] = -5.417856, states[40]= 0.002837
Saving checkpoint... 
Iteration: 1308680036, states[0] = -86.547795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319218895, states[0] = -86.541613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329711515, states[0] = -86.535373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340317423, states[0] = -86.454872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350801943, states[0] = -86.548417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361377052, states[0] = -86.539152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371810953, states[0] = -86.534544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382270799, states[0] = -86.403153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392644796, states[0] = -86.546773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402988127, states[0] = -86.545770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413406681, states[0] = -86.538733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423926384, states[0] = -86.533715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434374860, states[0] = -86.494699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444901852, states[0] = -86.547231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455412736, states[0] = -86.538644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465964788, states[0] = -86.533463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476533873, states[0] = -86.538696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486926747, states[0] = -86.546825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497326713, states[0] = -86.539860, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.409213
 - CaMKt in component CaMK (millimolar): 0.000879
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.031016
 - nass in component intracellular_ions (millimolar): 6.031060
 - ki in component intracellular_ions (millimolar): 145.966388
 - kss in component intracellular_ions (millimolar): 145.966377
 - cansr in component intracellular_ions (millimolar): 1.243263
 - cajsr in component intracellular_ions (millimolar): 1.243415
 - cai in component intracellular_ions (millimolar): 0.000070
 - m in component INa (dimensionless): 0.008512
 - hf in component INa (dimensionless): 0.644966
 - hs in component INa (dimensionless): 0.644967
 - j in component INa (dimensionless): 0.644969
 - hsp in component INa (dimensionless): 0.396100
 - jp in component INa (dimensionless): 0.644971
 - mL in component INaL (dimensionless): 0.000249
 - hL in component INaL (dimensionless): 0.464135
 - hLp in component INaL (dimensionless): 0.274285
 - a in component Ito (dimensionless): 0.001105
 - iF in component Ito (dimensionless): 0.999424
 - iS in component Ito (dimensionless): 0.985525
 - ap in component Ito (dimensionless): 0.000563
 - iFp in component Ito (dimensionless): 0.999424
 - iSp in component Ito (dimensionless): 0.991635
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997443
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001240
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020638
 - xs1 in component IKs (dimensionless): 0.037588
 - xs2 in component IKs (dimensionless): 0.000227
 - xk1 in component IK1 (dimensionless): 0.997123
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:41:49 (12404): called boinc_finish(0)

</stderr_txt>
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