𝕏

Task 55826079

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_181_1
Workunit 26511168
Created 2 Jul 2024, 14:33:33 UTC
Sent 3 Jul 2024, 4:42:07 UTC
Report deadline 6 Jul 2024, 4:42:07 UTC
Received 3 Jul 2024, 23:59:44 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220836
Run time 37 min 47 sec
CPU time 32 min 27 sec
Validate state Valid
Credit 43.03
Device peak FLOPS 5.24 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.36 MB
Peak swap size 391.88 GB
Peak disk usage 1.26 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_181.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_181_1_r159538870_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_181_1_r159538870_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.089411
     * GNaL_b in INaL: 0.005445
     * Gto_b in Ito: 0.082358
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032142
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.164177
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.419877
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034468
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 4127334, states[0] = -37.129196, states[40]= 0.000169
Saving checkpoint... 
Iteration: 7797689, states[0] = -86.786056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 12141794, states[0] = -47.732551, states[40]= 0.000035
Saving checkpoint... 
Iteration: 17239055, states[0] = -86.715008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20912988, states[0] = -86.696693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24895575, states[0] = -86.675589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28315425, states[0] = -86.565095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32561734, states[0] = -86.635127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36024638, states[0] = 20.472403, states[40]= 0.005946
Saving checkpoint... 
Iteration: 40935512, states[0] = -86.613703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44747652, states[0] = -86.604627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49605931, states[0] = -86.581943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53545249, states[0] = -86.574205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57877692, states[0] = -86.563151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61357923, states[0] = -86.562566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65365376, states[0] = -86.556432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70158345, states[0] = -54.265032, states[40]= 0.000012
Saving checkpoint... 
Iteration: 73832139, states[0] = -86.540788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78710931, states[0] = -86.549312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83639334, states[0] = -86.532714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88216001, states[0] = -86.308867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92658263, states[0] = -86.536911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97428542, states[0] = -86.525110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101530317, states[0] = -86.521481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105287276, states[0] = -86.522876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110421323, states[0] = -86.494256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114839609, states[0] = -86.526431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119616384, states[0] = -86.512606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124663765, states[0] = -86.522415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129552643, states[0] = -86.510249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133963196, states[0] = -86.505559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138106035, states[0] = -7.404928, states[40]= 0.002496
Saving checkpoint... 
Iteration: 141051370, states[0] = -86.515433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144355685, states[0] = -86.453312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148788401, states[0] = -86.518049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153738313, states[0] = -86.503432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158094620, states[0] = -0.345145, states[40]= 0.003641
Saving checkpoint... 
Iteration: 162153236, states[0] = -47.170603, states[40]= 0.000041
Saving checkpoint... 
Iteration: 166691289, states[0] = -86.515194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171283215, states[0] = -86.506890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176079907, states[0] = 6.208251, states[40]= 0.004138
Saving checkpoint... 
Iteration: 180319301, states[0] = -86.421425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184469780, states[0] = -86.493505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188387536, states[0] = -86.465880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192996350, states[0] = -86.510507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197434960, states[0] = -86.502722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200706744, states[0] = -86.512928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204545466, states[0] = -86.504550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209376202, states[0] = -86.503005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213410307, states[0] = -86.502365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218002739, states[0] = 33.198345, states[40]= 0.150287
Saving checkpoint... 
Iteration: 222262670, states[0] = -86.353843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227251349, states[0] = -86.504407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230095057, states[0] = -0.452036, states[40]= 0.003624
Saving checkpoint... 
Iteration: 233706334, states[0] = -86.498386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236970502, states[0] = -86.509424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240937186, states[0] = -86.509955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244476543, states[0] = -86.492761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249317402, states[0] = -86.502884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252141792, states[0] = -36.831801, states[40]= 0.000202
Saving checkpoint... 
Iteration: 256614828, states[0] = -86.508706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260124955, states[0] = -22.473268, states[40]= 0.000811
Saving checkpoint... 
Iteration: 264217864, states[0] = -86.283755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268560096, states[0] = -86.504630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272319579, states[0] = -86.418812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277218122, states[0] = -86.504229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281040221, states[0] = -86.507535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284945956, states[0] = -86.509294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289451281, states[0] = -86.500547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293116147, states[0] = -86.505996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296473480, states[0] = -86.491611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299734678, states[0] = -86.497388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302919787, states[0] = -86.509659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307394492, states[0] = -86.501242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311586445, states[0] = -86.498808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315172031, states[0] = -86.504858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319674943, states[0] = -86.497867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324048823, states[0] = 16.097014, states[40]= 0.004282
Saving checkpoint... 
Iteration: 327277501, states[0] = -86.502982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332074979, states[0] = 8.105777, states[40]= 0.004206
Saving checkpoint... 
Iteration: 335031749, states[0] = -86.507477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338962797, states[0] = -86.508783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342702207, states[0] = -86.510934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347600412, states[0] = -86.498567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351780226, states[0] = -86.496851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356308227, states[0] = -86.407851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360295012, states[0] = -86.393990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363566564, states[0] = -86.498918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368097339, states[0] = -1.642783, states[40]= 0.003471
Saving checkpoint... 
Iteration: 372550237, states[0] = -86.503274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376580641, states[0] = -86.506008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380450616, states[0] = -86.485932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384914494, states[0] = -86.509585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389691477, states[0] = -86.497600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394190815, states[0] = -84.820100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398323094, states[0] = -86.421526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402048157, states[0] = 16.274571, states[40]= 0.004285
Saving checkpoint... 
Iteration: 406925088, states[0] = -86.509390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411119160, states[0] = -86.505710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414809388, states[0] = -86.510974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420105422, states[0] = -6.642168, states[40]= 0.002634
Saving checkpoint... 
Iteration: 424390352, states[0] = -86.464536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427575445, states[0] = -86.498775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432349129, states[0] = -86.441402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437706121, states[0] = -86.497439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442948286, states[0] = -86.508963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445836932, states[0] = -86.496331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449426541, states[0] = -86.500615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454285087, states[0] = -86.382403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459284212, states[0] = -86.502754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462968563, states[0] = -86.508584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465536363, states[0] = -86.499211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470328728, states[0] = -86.426221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474320318, states[0] = -86.419078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477916474, states[0] = -86.495743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482721663, states[0] = -86.511055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486894273, states[0] = -86.509876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491190092, states[0] = -86.504369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495555526, states[0] = -86.498981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498797265, states[0] = -86.511041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501877305, states[0] = -86.496014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505495319, states[0] = -86.499700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509582078, states[0] = -86.498678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513369285, states[0] = -86.501415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516791635, states[0] = -86.511073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520809559, states[0] = -86.510942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525546786, states[0] = -86.499075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529738530, states[0] = -86.497123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533902478, states[0] = -86.495828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537433416, states[0] = -86.500501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542644876, states[0] = -86.509458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546847816, states[0] = -86.510530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551128505, states[0] = -86.505495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554701673, states[0] = -86.510823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560224540, states[0] = -86.293730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565435688, states[0] = -86.500464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570067437, states[0] = 10.672561, states[40]= 0.004266
Saving checkpoint... 
Iteration: 574786893, states[0] = -86.511088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579580665, states[0] = -86.498680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583139846, states[0] = -86.505276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586473705, states[0] = -86.491409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591133576, states[0] = -86.505392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595172235, states[0] = -86.504673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599394860, states[0] = -86.501027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604280303, states[0] = -86.376453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608116508, states[0] = -15.311913, states[40]= 0.001238
Saving checkpoint... 
Iteration: 613049864, states[0] = -86.506995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616325135, states[0] = -86.423208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621349629, states[0] = -86.501689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626024440, states[0] = 21.337064, states[40]= 0.006135
Saving checkpoint... 
Iteration: 631030979, states[0] = -86.507358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634565456, states[0] = -86.504670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639266845, states[0] = -86.503005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643226378, states[0] = -86.503696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647622110, states[0] = -86.498222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652865366, states[0] = -86.510278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657309432, states[0] = -86.502307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661416305, states[0] = -86.500713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666559497, states[0] = -86.504113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671403829, states[0] = -86.500886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675238128, states[0] = -86.503486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679429795, states[0] = -86.500524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684670690, states[0] = -86.510210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688888219, states[0] = -86.509933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692664079, states[0] = -86.510037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697000933, states[0] = -86.507925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701176115, states[0] = -86.504583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704913354, states[0] = -86.509522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709531844, states[0] = -86.499217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714937827, states[0] = -86.509095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719084553, states[0] = -86.506304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723402613, states[0] = -86.500894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727785137, states[0] = -86.496687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730763948, states[0] = -86.511138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734434308, states[0] = -86.481162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739381347, states[0] = -86.501196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742828350, states[0] = -86.510721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747528242, states[0] = -86.499253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751467859, states[0] = -86.500004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754775009, states[0] = -86.511107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758599795, states[0] = -86.507237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762150523, states[0] = -44.459508, states[40]= 0.000063
Saving checkpoint... 
Iteration: 766637766, states[0] = -86.509148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770828012, states[0] = -86.510720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774107441, states[0] = -8.082372, states[40]= 0.002362
Saving checkpoint... 
Iteration: 777830315, states[0] = -86.496316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781564522, states[0] = -86.498825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785642717, states[0] = -86.497985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790026828, states[0] = 21.005497, states[40]= 0.005585
Saving checkpoint... 
Iteration: 794058730, states[0] = 13.340345, states[40]= 0.004280
Saving checkpoint... 
Iteration: 798200495, states[0] = -86.145536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803119714, states[0] = -86.505616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807258138, states[0] = -86.503121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810699534, states[0] = -86.510746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815706385, states[0] = -86.497362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819751072, states[0] = -86.496960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823531718, states[0] = -86.499198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826991370, states[0] = -86.508084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831671027, states[0] = -86.497695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836214469, states[0] = -86.277106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840331029, states[0] = -86.428010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844284888, states[0] = -86.382086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848799479, states[0] = -86.510961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853998937, states[0] = -86.495136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858310394, states[0] = -86.409830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863255970, states[0] = -86.503148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867561838, states[0] = -86.498840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871445207, states[0] = -86.500281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876030496, states[0] = 20.387872, states[40]= 0.005052
Saving checkpoint... 
Iteration: 881123128, states[0] = -86.505537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886259455, states[0] = -86.347868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890280317, states[0] = -86.376419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895057464, states[0] = -86.506797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899136066, states[0] = -86.505290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903341326, states[0] = -86.501764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906242201, states[0] = -86.321382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909811379, states[0] = -86.496441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913704127, states[0] = -86.497365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917834155, states[0] = -86.496261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922786074, states[0] = -86.511030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926852383, states[0] = -86.510403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930407005, states[0] = -86.471558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935255390, states[0] = -86.503144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940089521, states[0] = 2.257215, states[40]= 0.003893
Saving checkpoint... 
Iteration: 944429315, states[0] = -86.479547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948098682, states[0] = -2.393113, states[40]= 0.003364
Saving checkpoint... 
Iteration: 952538778, states[0] = -86.501868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956492495, states[0] = -86.495061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959592652, states[0] = -86.498480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963179074, states[0] = -86.504482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967533756, states[0] = -86.499148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971732204, states[0] = -86.497099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976505844, states[0] = -86.497333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980328148, states[0] = -86.425651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984999971, states[0] = -86.507892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989279023, states[0] = -86.502740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993982013, states[0] = -86.495216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999071881, states[0] = -86.506499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003563640, states[0] = -86.498795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007912202, states[0] = -86.495674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012417337, states[0] = -86.475446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015830366, states[0] = -86.496273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019068255, states[0] = -86.506565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023956493, states[0] = -86.495374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028106590, states[0] = -7.465682, states[40]= 0.002478
Saving checkpoint... 
Iteration: 1033100520, states[0] = -86.505941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037301938, states[0] = -86.502358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041410415, states[0] = -86.500726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045812967, states[0] = -86.496404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050555289, states[0] = -86.503634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054744543, states[0] = -86.511069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059403928, states[0] = -86.500814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063177249, states[0] = -86.504497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068049375, states[0] = 15.951217, states[40]= 0.004280
Saving checkpoint... 
Iteration: 1072461359, states[0] = -86.488504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077272997, states[0] = -86.502824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081508756, states[0] = -86.499428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086524334, states[0] = -86.500031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091044984, states[0] = -86.507003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095473009, states[0] = -86.499875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099910312, states[0] = -86.495670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103460377, states[0] = -86.500038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108057697, states[0] = 13.640101, states[40]= 0.004279
Saving checkpoint... 
Iteration: 1113349597, states[0] = -86.501600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117658058, states[0] = -86.497771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122327004, states[0] = -86.424681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126964622, states[0] = -86.508533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130473660, states[0] = -86.491301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134620070, states[0] = -86.508298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138287704, states[0] = -86.385412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142270343, states[0] = -86.363272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147214292, states[0] = -86.503817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151986972, states[0] = -86.495156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155602289, states[0] = -86.498340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159926320, states[0] = -86.495549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163891475, states[0] = -86.495791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167602412, states[0] = -86.498337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172152055, states[0] = -45.832952, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1176498989, states[0] = -86.496164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180236446, states[0] = -86.312213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184464520, states[0] = -86.489235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189813923, states[0] = -86.496370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194030377, states[0] = 20.409779, states[40]= 0.005065
Saving checkpoint... 
Iteration: 1197900923, states[0] = -86.495718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202751223, states[0] = -86.511055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207968369, states[0] = -86.495264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211989295, states[0] = -86.495131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215527492, states[0] = -86.499177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219930358, states[0] = -86.495511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223509142, states[0] = -86.499398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227431506, states[0] = -86.500401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232029156, states[0] = 20.627506, states[40]= 0.005216
Saving checkpoint... 
Iteration: 1236382745, states[0] = -86.460746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241553416, states[0] = -86.498869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244572572, states[0] = -86.505176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249798128, states[0] = -86.496486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254197935, states[0] = -86.028088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258443195, states[0] = -86.483703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262813872, states[0] = -86.510770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266434848, states[0] = -86.481233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270640698, states[0] = -86.509171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274789004, states[0] = -86.510951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278735501, states[0] = -86.510996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282985671, states[0] = -86.508110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287202959, states[0] = -86.503993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290686102, states[0] = -86.510436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294966817, states[0] = -86.508462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299887119, states[0] = -86.495798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304527914, states[0] = -86.500465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308130711, states[0] = -27.317487, states[40]= 0.000620
Saving checkpoint... 
Iteration: 1312558743, states[0] = -86.503925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316558230, states[0] = -86.503875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321711733, states[0] = -86.497221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326802258, states[0] = -86.510854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330600473, states[0] = -86.507176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335234350, states[0] = -86.503432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340172296, states[0] = -65.778948, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1344100837, states[0] = -3.660854, states[40]= 0.003166
Saving checkpoint... 
Iteration: 1347932523, states[0] = -86.495474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353034239, states[0] = -86.507164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357302136, states[0] = -86.502297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362191634, states[0] = -85.080173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365271947, states[0] = -86.502789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370229750, states[0] = -86.301635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375000066, states[0] = -86.507819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379328543, states[0] = -86.501876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382254464, states[0] = -86.340330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386883182, states[0] = -86.509884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390763135, states[0] = -86.511020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394783617, states[0] = -86.510957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399573508, states[0] = -86.498612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404792926, states[0] = -86.510904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409219220, states[0] = -86.503683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412918819, states[0] = -86.509302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416813833, states[0] = -86.510742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422205534, states[0] = -86.238428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426556368, states[0] = -86.503673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431363051, states[0] = -86.501341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436447474, states[0] = -86.484866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440652923, states[0] = -86.509570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444507971, states[0] = -86.497586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449033899, states[0] = -86.507154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454191697, states[0] = -85.098305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459303798, states[0] = -86.502252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462445800, states[0] = -86.484399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466908882, states[0] = -86.509460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470635871, states[0] = -86.508945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475740923, states[0] = -86.496930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478830348, states[0] = -86.510567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483637017, states[0] = -86.497917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488784277, states[0] = -86.510937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493076353, states[0] = -86.506323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496266470, states[0] = -86.357845, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.370982
 - CaMKt in component CaMK (millimolar): 0.000879
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.051214
 - nass in component intracellular_ions (millimolar): 6.051258
 - ki in component intracellular_ions (millimolar): 145.945892
 - kss in component intracellular_ions (millimolar): 145.945881
 - cansr in component intracellular_ions (millimolar): 1.244697
 - cajsr in component intracellular_ions (millimolar): 1.244840
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008545
 - hf in component INa (dimensionless): 0.643526
 - hs in component INa (dimensionless): 0.643527
 - j in component INa (dimensionless): 0.643530
 - hsp in component INa (dimensionless): 0.394599
 - jp in component INa (dimensionless): 0.643531
 - mL in component INaL (dimensionless): 0.000251
 - hL in component INaL (dimensionless): 0.462866
 - hLp in component INaL (dimensionless): 0.273278
 - a in component Ito (dimensionless): 0.001108
 - iF in component Ito (dimensionless): 0.999420
 - iS in component Ito (dimensionless): 0.985568
 - ap in component Ito (dimensionless): 0.000565
 - iFp in component Ito (dimensionless): 0.999420
 - iSp in component Ito (dimensionless): 0.991664
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997535
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001246
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020459
 - xs1 in component IKs (dimensionless): 0.036808
 - xs2 in component IKs (dimensionless): 0.000228
 - xk1 in component IK1 (dimensionless): 0.997132
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:41:48 (65175): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_181.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_181_1_r159538870_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_181_1_r159538870_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.089411
     * GNaL_b in INaL: 0.005445
     * Gto_b in Ito: 0.082358
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032142
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.164177
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.419877
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034468
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1496266470
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.357845 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.370982
 - CaMKt in component CaMK (millimolar): 0.000879
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.051214
 - nass in component intracellular_ions (millimolar): 6.051258
 - ki in component intracellular_ions (millimolar): 145.945892
 - kss in component intracellular_ions (millimolar): 145.945881
 - cansr in component intracellular_ions (millimolar): 1.244697
 - cajsr in component intracellular_ions (millimolar): 1.244840
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008545
 - hf in component INa (dimensionless): 0.643526
 - hs in component INa (dimensionless): 0.643527
 - j in component INa (dimensionless): 0.643530
 - hsp in component INa (dimensionless): 0.394599
 - jp in component INa (dimensionless): 0.643531
 - mL in component INaL (dimensionless): 0.000251
 - hL in component INaL (dimensionless): 0.462866
 - hLp in component INaL (dimensionless): 0.273278
 - a in component Ito (dimensionless): 0.001108
 - iF in component Ito (dimensionless): 0.999420
 - iS in component Ito (dimensionless): 0.985568
 - ap in component Ito (dimensionless): 0.000565
 - iFp in component Ito (dimensionless): 0.999420
 - iSp in component Ito (dimensionless): 0.991664
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997535
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001246
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020459
 - xs1 in component IKs (dimensionless): 0.036808
 - xs2 in component IKs (dimensionless): 0.000228
 - xk1 in component IK1 (dimensionless): 0.997132
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:44:59 (65984): called boinc_finish(0)

</stderr_txt>
]]>


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