𝕏

Task 55821577

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_10000-conf_977_1
Workunit 26508919
Created 2 Jul 2024, 14:31:33 UTC
Sent 3 Jul 2024, 4:03:33 UTC
Report deadline 6 Jul 2024, 4:03:33 UTC
Received 6 Jul 2024, 1:46:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220129
Run time 2 hours 39 min 24 sec
CPU time 2 hours 11 min 6 sec
Validate state Valid
Credit 44.64
Device peak FLOPS 3.26 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.79 MB
Peak swap size 4.10 GB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_10000-conf_977.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_10000-conf_977_1_r914864462_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_EPI_10000-conf_977_1_r914864462_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.338684
     * GNaL_b in INaL: 0.005763
     * Gto_b in Ito: 0.081566
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032093
     * GKs_b in IKs: 0.001911
     * GK1_b in IK1: 0.160418
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.610143
     * GKb_b in IKb: 0.003820
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033037
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 4902363, states[0] = -94.331626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 9871571, states[0] = -94.273150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15332301, states[0] = -94.114075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20272998, states[0] = -93.922996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25098987, states[0] = 7.049613, states[40]= 0.000018
Saving checkpoint... 
Iteration: 30898296, states[0] = -94.182180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35610506, states[0] = -94.175287, states[40]= 0.000000
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Iteration: 40712222, states[0] = -94.170195, states[40]= 0.000000
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Iteration: 45251070, states[0] = -93.731832, states[40]= 0.000000
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Iteration: 50955537, states[0] = -94.154193, states[40]= 0.000000
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Iteration: 55491068, states[0] = -94.138648, states[40]= 0.000000
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Iteration: 60992322, states[0] = -94.150091, states[40]= 0.000000
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Iteration: 66444357, states[0] = -94.134901, states[40]= 0.000000
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Iteration: 71143698, states[0] = -94.144180, states[40]= 0.000000
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Iteration: 76262799, states[0] = -94.140625, states[40]= 0.000000
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Iteration: 81111762, states[0] = -94.146439, states[40]= 0.000000
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Iteration: 86567335, states[0] = -94.134021, states[40]= 0.000000
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Iteration: 121802426, states[0] = -94.134128, states[40]= 0.000000
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Iteration: 126888733, states[0] = -94.133261, states[40]= 0.000000
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Iteration: 132655430, states[0] = -94.126247, states[40]= 0.000000
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Iteration: 142836567, states[0] = -94.125896, states[40]= 0.000000
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Iteration: 148040898, states[0] = -94.125235, states[40]= 0.000000
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Iteration: 153091532, states[0] = -94.125270, states[40]= 0.000000
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Iteration: 158065796, states[0] = -94.125578, states[40]= 0.000000
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Iteration: 163487144, states[0] = -94.124391, states[40]= 0.000000
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Iteration: 168566413, states[0] = -94.124347, states[40]= 0.000000
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Iteration: 173672466, states[0] = -94.124237, states[40]= 0.000000
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Iteration: 179204447, states[0] = -94.123449, states[40]= 0.000000
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Iteration: 184839869, states[0] = -94.122907, states[40]= 0.000000
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Iteration: 193310060, states[0] = -94.125549, states[40]= 0.000000
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Iteration: 198924426, states[0] = -94.124171, states[40]= 0.000000
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Iteration: 204243635, states[0] = -94.123747, states[40]= 0.000000
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Iteration: 208730047, states[0] = -94.124623, states[40]= 0.000000
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Iteration: 213686401, states[0] = -94.124747, states[40]= 0.000000
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Iteration: 218567665, states[0] = -94.125043, states[40]= 0.000000
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Iteration: 223562679, states[0] = -94.125075, states[40]= 0.000000
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Iteration: 228470901, states[0] = -94.125323, states[40]= 0.000000
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Iteration: 233662001, states[0] = -94.124868, states[40]= 0.000000
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Iteration: 239083060, states[0] = -94.124108, states[40]= 0.000000
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Iteration: 244239773, states[0] = -94.123893, states[40]= 0.000000
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Iteration: 249566946, states[0] = -94.123526, states[40]= 0.000000
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Iteration: 254213524, states[0] = -94.123922, states[40]= 0.000000
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Iteration: 259445479, states[0] = -94.123639, states[40]= 0.000000
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Iteration: 264475140, states[0] = -94.123600, states[40]= 0.000000
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Iteration: 269822274, states[0] = -94.123274, states[40]= 0.000000
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Iteration: 274173122, states[0] = -94.123939, states[40]= 0.000000
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Iteration: 279690104, states[0] = -94.123358, states[40]= 0.000000
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Iteration: 284588550, states[0] = -94.123437, states[40]= 0.000000
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Iteration: 289805295, states[0] = -94.123232, states[40]= 0.000000
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Iteration: 304591367, states[0] = -94.123368, states[40]= 0.000000
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Iteration: 309505294, states[0] = -94.123434, states[40]= 0.000000
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Iteration: 314278874, states[0] = -94.123671, states[40]= 0.000000
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Iteration: 319792836, states[0] = -94.123134, states[40]= 0.000000
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Iteration: 325363247, states[0] = -94.053094, states[40]= 0.000000
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Iteration: 330511084, states[0] = -94.153262, states[40]= 0.000000
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Iteration: 335611498, states[0] = -94.167699, states[40]= 0.000000
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Iteration: 340581048, states[0] = -94.165223, states[40]= 0.000000
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Iteration: 346129986, states[0] = -94.154139, states[40]= 0.000000
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Iteration: 351229574, states[0] = -94.150648, states[40]= 0.000000
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Iteration: 356149135, states[0] = -94.153398, states[40]= 0.000000
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Iteration: 361325665, states[0] = -94.147632, states[40]= 0.000000
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Iteration: 366436662, states[0] = -94.144594, states[40]= 0.000000
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Iteration: 371849751, states[0] = -94.136387, states[40]= 0.000000
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Iteration: 377397974, states[0] = -94.130150, states[40]= 0.000000
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Iteration: 383030763, states[0] = -94.126359, states[40]= 0.000000
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Iteration: 388802854, states[0] = -94.124096, states[40]= 0.000000
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Iteration: 393927217, states[0] = -94.123847, states[40]= 0.000000
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Iteration: 398117799, states[0] = -94.125944, states[40]= 0.000000
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Iteration: 403220502, states[0] = -94.125549, states[40]= 0.000000
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Iteration: 408112118, states[0] = -94.125921, states[40]= 0.000000
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Iteration: 413524594, states[0] = -94.124602, states[40]= 0.000000
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Iteration: 418969087, states[0] = -94.123665, states[40]= 0.000000
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Iteration: 424380998, states[0] = -94.123076, states[40]= 0.000000
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Iteration: 429330281, states[0] = -94.123112, states[40]= 0.000000
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Iteration: 434512470, states[0] = -94.122890, states[40]= 0.000000
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Iteration: 439940606, states[0] = -94.122499, states[40]= 0.000000
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Iteration: 444797084, states[0] = -94.122587, states[40]= 0.000000
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Iteration: 449407402, states[0] = -94.122934, states[40]= 0.000000
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Iteration: 453870357, states[0] = -94.123678, states[40]= 0.000000
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Iteration: 458726983, states[0] = -94.123934, states[40]= 0.000000
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Iteration: 462865127, states[0] = -94.126758, states[40]= 0.000000
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Iteration: 468040214, states[0] = -94.125939, states[40]= 0.000000
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Iteration: 473087221, states[0] = -94.125726, states[40]= 0.000000
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Iteration: 477739686, states[0] = -94.127358, states[40]= 0.000000
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Iteration: 482472269, states[0] = -94.129094, states[40]= 0.000000
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Iteration: 487165019, states[0] = -94.131839, states[40]= 0.000000
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Iteration: 492479248, states[0] = -94.128996, states[40]= 0.000000
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Iteration: 497305319, states[0] = -94.130413, states[40]= 0.000000
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Iteration: 502220920, states[0] = -94.131195, states[40]= 0.000000
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Iteration: 507360808, states[0] = -94.129879, states[40]= 0.000000
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Iteration: 512202312, states[0] = -94.131337, states[40]= 0.000000
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Iteration: 522642082, states[0] = -94.127739, states[40]= 0.000000
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Iteration: 527357003, states[0] = -94.129821, states[40]= 0.000000
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Iteration: 531628738, states[0] = -94.139533, states[40]= 0.000000
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Iteration: 537074889, states[0] = -94.132621, states[40]= 0.000000
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Iteration: 542678087, states[0] = -94.127426, states[40]= 0.000000
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Iteration: 547744494, states[0] = -94.127014, states[40]= 0.000000
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Iteration: 552633018, states[0] = -94.127661, states[40]= 0.000000
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Iteration: 557419221, states[0] = -94.129169, states[40]= 0.000000
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Iteration: 561952368, states[0] = -94.134057, states[40]= 0.000000
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Iteration: 571141051, states[0] = -94.152729, states[40]= 0.000000
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Iteration: 575678567, states[0] = -94.168649, states[40]= 0.000000
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Iteration: 580615198, states[0] = -94.166829, states[40]= 0.000000
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Iteration: 585633604, states[0] = -94.167681, states[40]= 0.000000
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Iteration: 590809061, states[0] = -94.165957, states[40]= 0.000000
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Iteration: 595312029, states[0] = -93.954650, states[40]= 0.000000
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Iteration: 600296414, states[0] = -93.911317, states[40]= 0.000000
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Iteration: 605427705, states[0] = -94.115615, states[40]= 0.000000
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Iteration: 609987383, states[0] = -94.121698, states[40]= 0.000000
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Iteration: 614313166, states[0] = -94.122297, states[40]= 0.000000
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Iteration: 624202153, states[0] = -94.122392, states[40]= 0.000000
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Iteration: 629704660, states[0] = -94.121827, states[40]= 0.000000
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Iteration: 635033114, states[0] = 27.039324, states[40]= 0.000000
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Iteration: 639703905, states[0] = -94.121783, states[40]= 0.000000
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Iteration: 704488163, states[0] = -94.121694, states[40]= 0.000000
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Iteration: 708684872, states[0] = -94.122893, states[40]= 0.000000
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Iteration: 712743177, states[0] = -94.126275, states[40]= 0.000000
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Iteration: 716860516, states[0] = -94.134670, states[40]= 0.000000
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Iteration: 810999138, states[0] = -94.157194, states[40]= 0.000000
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Iteration: 913218805, states[0] = -94.123249, states[40]= 0.000000
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Iteration: 928909521, states[0] = -94.121460, states[40]= 0.000000
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Iteration: 933958679, states[0] = -94.121353, states[40]= 0.000000
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Iteration: 939581556, states[0] = -94.120537, states[40]= 0.000000
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Iteration: 989492632, states[0] = -94.120399, states[40]= 0.000000
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Iteration: 994073200, states[0] = -94.120900, states[40]= 0.000000
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Iteration: 999577109, states[0] = -94.120269, states[40]= 0.000000
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Iteration: 1004969473, states[0] = -94.119922, states[40]= 0.000000
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Iteration: 1010130675, states[0] = -20.418301, states[40]= 0.000264
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Iteration: 1015734935, states[0] = -94.166185, states[40]= 0.000000
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Iteration: 1038094138, states[0] = -94.123143, states[40]= 0.000000
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Iteration: 1043535455, states[0] = -94.121726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048600997, states[0] = -94.121544, states[40]= 0.000000
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Iteration: 1054349407, states[0] = -94.120262, states[40]= 0.000000
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Iteration: 1059324170, states[0] = -94.120270, states[40]= 0.000000
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Iteration: 1064581461, states[0] = -94.119971, states[40]= 0.000000
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Iteration: 1069293365, states[0] = -94.120262, states[40]= 0.000000
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Iteration: 1074271838, states[0] = -94.120266, states[40]= 0.000000
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Iteration: 1078916544, states[0] = -94.120769, states[40]= 0.000000
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Iteration: 1084645830, states[0] = -94.119820, states[40]= 0.000000
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Iteration: 1090293695, states[0] = -93.900670, states[40]= 0.000000
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Iteration: 1096152992, states[0] = -94.149927, states[40]= 0.000000
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Iteration: 1101775772, states[0] = -94.134274, states[40]= 0.000000
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Iteration: 1106550222, states[0] = -94.138578, states[40]= 0.000000
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Iteration: 1112041611, states[0] = -94.130421, states[40]= 0.000000
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Iteration: 1117166438, states[0] = -94.128975, states[40]= 0.000000
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Iteration: 1122533491, states[0] = -94.125751, states[40]= 0.000000
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Iteration: 1126861351, states[0] = -94.132803, states[40]= 0.000000
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Iteration: 1131140821, states[0] = -94.150210, states[40]= 0.000000
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Iteration: 1135926876, states[0] = -94.158764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141141132, states[0] = -94.150153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146812397, states[0] = -94.133472, states[40]= 0.000000
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Iteration: 1152068616, states[0] = -94.129914, states[40]= 0.000000
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Iteration: 1156355575, states[0] = -94.143194, states[40]= 0.000000
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Iteration: 1160438772, states[0] = -94.120133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165126305, states[0] = -15.843379, states[40]= 0.000235
Saving checkpoint... 
Iteration: 1169464594, states[0] = -94.119614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174381054, states[0] = -94.119683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179568986, states[0] = -94.119462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184875232, states[0] = -94.119177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189814203, states[0] = -94.119201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195550442, states[0] = -94.157451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201378843, states[0] = -94.142347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206034600, states[0] = -94.153960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211669300, states[0] = -94.135671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217095210, states[0] = -94.129310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221748297, states[0] = -94.134197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226358784, states[0] = -94.142788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231074359, states[0] = -94.152267, states[40]= 0.000000
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Iteration: 1236566730, states[0] = -94.137631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242410015, states[0] = -94.126144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247412445, states[0] = -94.126102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252424969, states[0] = -94.125979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257448450, states[0] = -94.125771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261685194, states[0] = -94.135147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267249451, states[0] = -94.127455, states[40]= 0.000000
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Iteration: 1272533001, states[0] = -94.125076, states[40]= 0.000000
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Iteration: 1278222340, states[0] = -94.121585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282841045, states[0] = -94.123170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287978921, states[0] = -94.122491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292996918, states[0] = -94.122390, states[40]= 0.000000
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Iteration: 1297998154, states[0] = -94.122362, states[40]= 0.000000
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Iteration: 1302640534, states[0] = -94.124220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307082387, states[0] = -94.129051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312170698, states[0] = -94.128048, states[40]= 0.000000
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Iteration: 1317365645, states[0] = -94.126174, states[40]= 0.000000
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Iteration: 1322876799, states[0] = -94.122809, states[40]= 0.000000
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Iteration: 1328511598, states[0] = -94.120496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334191946, states[0] = -94.119193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338483268, states[0] = -94.120525, states[40]= 0.000000
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Iteration: 1343129087, states[0] = -94.121628, states[40]= 0.000000
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Iteration: 1348496472, states[0] = -94.120445, states[40]= 0.000000
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Iteration: 1354133020, states[0] = -94.119183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359688386, states[0] = -94.118537, states[40]= 0.000000
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Iteration: 1365419320, states[0] = -94.106248, states[40]= 0.000000
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Iteration: 1370510703, states[0] = -94.148490, states[40]= 0.000000
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Iteration: 1376179937, states[0] = -94.147709, states[40]= 0.000000
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Iteration: 1381045985, states[0] = -94.152712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386542586, states[0] = -94.137481, states[40]= 0.000000
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Iteration: 1391235251, states[0] = -94.145776, states[40]= 0.000000
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Iteration: 1396156389, states[0] = -94.148451, states[40]= 0.000000
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Iteration: 1401483240, states[0] = -94.138779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407099579, states[0] = -94.128400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412044793, states[0] = -94.129025, states[40]= 0.000000
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Iteration: 1416244952, states[0] = -94.145349, states[40]= 0.000000
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Iteration: 1419903158, states[0] = -94.118092, states[40]= 0.000000
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Iteration: 1425462367, states[0] = -94.131295, states[40]= 0.000000
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Iteration: 1430955942, states[0] = -94.156204, states[40]= 0.000000
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Iteration: 1436634319, states[0] = -94.135332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441729028, states[0] = -94.133538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445928801, states[0] = -94.157284, states[40]= 0.000000
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Iteration: 1450859654, states[0] = -94.160141, states[40]= 0.000000
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Iteration: 1455687447, states[0] = -94.164707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461518435, states[0] = -94.137686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466402676, states[0] = -94.140510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472167583, states[0] = -94.127357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477319121, states[0] = -94.125856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482996128, states[0] = -94.121534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487662196, states[0] = -94.123247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491731741, states[0] = -94.133265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496818431, states[0] = -94.131794, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.993647
 - CaMKt in component CaMK (millimolar): 0.000983
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.950364
 - nass in component intracellular_ions (millimolar): 6.950496
 - ki in component intracellular_ions (millimolar): 144.796158
 - kss in component intracellular_ions (millimolar): 144.796147
 - cansr in component intracellular_ions (millimolar): 2.350502
 - cajsr in component intracellular_ions (millimolar): 2.350621
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003966
 - hf in component INa (dimensionless): 0.863326
 - hs in component INa (dimensionless): 0.863326
 - j in component INa (dimensionless): 0.863326
 - hsp in component INa (dimensionless): 0.695182
 - jp in component INa (dimensionless): 0.863326
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.704556
 - hLp in component INaL (dimensionless): 0.510279
 - a in component Ito (dimensionless): 0.000663
 - iF in component Ito (dimensionless): 0.999847
 - iS in component Ito (dimensionless): 0.999847
 - ap in component Ito (dimensionless): 0.000338
 - iFp in component Ito (dimensionless): 0.999847
 - iSp in component Ito (dimensionless): 0.999847
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999992
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005170
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000006
 - xs1 in component IKs (dimensionless): 0.002071
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997566
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:46:30 (99941): called boinc_finish(0)

</stderr_txt>
]]>