𝕏

Task 55813763

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_368_0
Workunit 26505014
Created 2 Jul 2024, 14:28:02 UTC
Sent 3 Jul 2024, 3:05:43 UTC
Report deadline 6 Jul 2024, 12:41:43 UTC
Received 3 Jul 2024, 6:59:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215734
Run time 2 hours 48 min 48 sec
CPU time 2 hours 42 min 51 sec
Validate state Valid
Credit 63.47
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.71 MB
Peak swap size 5.26 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_368.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_368_0_r501264612_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_368_0_r501264612_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.566420
     * GNaL_b in INaL: 0.005520
     * Gto_b in Ito: 0.084399
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031804
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.163445
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.140392
     * GKb_b in IKb: 0.003793
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031208
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10459859, states[0] = -95.129217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24175845, states[0] = -94.831763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37727084, states[0] = -94.921788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51620380, states[0] = -40.894785, states[40]= 0.000113
Saving checkpoint... 
Iteration: 65641953, states[0] = -63.905772, states[40]= 0.000003
Saving checkpoint... 
Iteration: 79360389, states[0] = -95.012350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93126232, states[0] = -45.741829, states[40]= 0.000054
Saving checkpoint... 
Iteration: 106791452, states[0] = -94.964082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120548722, states[0] = 11.961152, states[40]= 0.004982
Saving checkpoint... 
Iteration: 134464703, states[0] = -95.032422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148164429, states[0] = -93.152829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157624254, states[0] = -43.283371, states[40]= 0.000079
Saving checkpoint... 
Iteration: 171190470, states[0] = -94.812973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184834642, states[0] = -94.989476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198653359, states[0] = -78.705186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212489652, states[0] = -95.034116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226211894, states[0] = -94.855830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239742586, states[0] = -94.905648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253322548, states[0] = -94.981926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266961236, states[0] = -95.029719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280678207, states[0] = -94.763258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294349192, states[0] = -94.996447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307978265, states[0] = -95.032310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321646148, states[0] = -67.777190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 335493241, states[0] = -95.034286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345735981, states[0] = -94.895961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359738854, states[0] = -94.900172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373668189, states[0] = -94.230043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387412001, states[0] = -95.019099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401360717, states[0] = -95.001599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415043935, states[0] = 13.832009, states[40]= 0.005085
Saving checkpoint... 
Iteration: 428695045, states[0] = -94.822071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442571663, states[0] = 2.004139, states[40]= 0.004474
Saving checkpoint... 
Iteration: 456194280, states[0] = -94.820426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470132890, states[0] = -52.328524, states[40]= 0.000019
Saving checkpoint... 
Iteration: 484058832, states[0] = 7.947572, states[40]= 0.004845
Saving checkpoint... 
Iteration: 497770270, states[0] = -94.939031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511044830, states[0] = 13.496523, states[40]= 0.005061
Saving checkpoint... 
Iteration: 524039664, states[0] = 15.398554, states[40]= 0.005241
Saving checkpoint... 
Iteration: 537380091, states[0] = -95.009123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551078683, states[0] = -1.987702, states[40]= 0.003949
Saving checkpoint... 
Iteration: 562523217, states[0] = 20.451445, states[40]= 0.007672
Saving checkpoint... 
Iteration: 576077288, states[0] = -1.131187, states[40]= 0.004084
Saving checkpoint... 
Iteration: 589905676, states[0] = -95.017235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603848320, states[0] = -94.995807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617591469, states[0] = -11.813942, states[40]= 0.001979
Saving checkpoint... 
Iteration: 631174371, states[0] = -94.700353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644284665, states[0] = -94.953009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658046411, states[0] = 12.898872, states[40]= 0.005025
Saving checkpoint... 
Iteration: 671811472, states[0] = -94.974315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685318585, states[0] = -94.979070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698974935, states[0] = -95.031560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712887886, states[0] = -95.011701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726624331, states[0] = -43.290041, states[40]= 0.000079
Saving checkpoint... 
Iteration: 740242468, states[0] = -94.905062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753855602, states[0] = -94.999116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767394802, states[0] = -95.013895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781046776, states[0] = 12.760008, states[40]= 0.005017
Saving checkpoint... 
Iteration: 791001917, states[0] = 44.914410, states[40]= 0.087398
Saving checkpoint... 
Iteration: 804630335, states[0] = -49.577270, states[40]= 0.000030
Saving checkpoint... 
Iteration: 818297008, states[0] = -94.963429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827933973, states[0] = -95.024095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841419485, states[0] = -95.020726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854952622, states[0] = -95.027789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868605760, states[0] = -25.252632, states[40]= 0.000690
Saving checkpoint... 
Iteration: 882299419, states[0] = -94.965296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896187704, states[0] = -94.805211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910213521, states[0] = -94.858250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924036936, states[0] = 16.360658, states[40]= 0.005388
Saving checkpoint... 
Iteration: 937607836, states[0] = -27.222792, states[40]= 0.000598
Saving checkpoint... 
Iteration: 951260297, states[0] = -94.927698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964889132, states[0] = -95.011950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978775642, states[0] = -94.944214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992543509, states[0] = 13.991086, states[40]= 0.005098
Saving checkpoint... 
Iteration: 1006012009, states[0] = 22.559339, states[40]= 0.033103
Saving checkpoint... 
Iteration: 1019820369, states[0] = -94.979997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033723706, states[0] = -94.876074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047367859, states[0] = -95.004150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060912966, states[0] = -95.018918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074829816, states[0] = -94.985693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088729904, states[0] = -94.886140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102825779, states[0] = -94.983290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116775282, states[0] = -94.943765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130604582, states[0] = -24.135638, states[40]= 0.000742
Saving checkpoint... 
Iteration: 1144304004, states[0] = -94.968632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156998114, states[0] = -95.034342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170305390, states[0] = -94.969643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184504633, states[0] = 29.267164, states[40]= 0.153186
Saving checkpoint... 
Iteration: 1198564494, states[0] = 5.473840, states[40]= 0.004736
Saving checkpoint... 
Iteration: 1212024632, states[0] = 20.105859, states[40]= 0.007160
Saving checkpoint... 
Iteration: 1225130567, states[0] = -49.825096, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1238573760, states[0] = 0.888283, states[40]= 0.004353
Saving checkpoint... 
Iteration: 1250988350, states[0] = -95.033067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264029327, states[0] = 18.817609, states[40]= 0.006137
Saving checkpoint... 
Iteration: 1277143331, states[0] = -64.191608, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1292745191, states[0] = -94.908454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301606527, states[0] = -25.979909, states[40]= 0.000656
Saving checkpoint... 
Iteration: 1314841037, states[0] = -94.991694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328421183, states[0] = -95.020829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341948985, states[0] = -95.026800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355198426, states[0] = -94.828526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368910068, states[0] = -95.017945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382074603, states[0] = 0.423175, states[40]= 0.004297
Saving checkpoint... 
Iteration: 1395831038, states[0] = -94.986189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409068565, states[0] = 3.561232, states[40]= 0.004611
Saving checkpoint... 
Iteration: 1422662553, states[0] = -91.943798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436255263, states[0] = -94.921367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449850350, states[0] = -94.996233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459535256, states[0] = 16.934787, states[40]= 0.005503
Saving checkpoint... 
Iteration: 1473225507, states[0] = -94.878785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486774772, states[0] = -94.943015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500259706, states[0] = -95.189789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513849910, states[0] = 8.254556, states[40]= 0.005549
Saving checkpoint... 
Iteration: 1527636037, states[0] = 14.816046, states[40]= 0.006344
Saving checkpoint... 
Iteration: 1536979980, states[0] = -15.255502, states[40]= 0.001606
Saving checkpoint... 
Iteration: 1550528677, states[0] = -74.097687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1563738620, states[0] = -91.101662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577624154, states[0] = -95.232730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591243469, states[0] = 10.854526, states[40]= 0.005852
Saving checkpoint... 
Iteration: 1604685250, states[0] = -95.300539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618390892, states[0] = -95.179239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631804766, states[0] = -43.775065, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1645353038, states[0] = -95.049451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656865812, states[0] = -95.286599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669821271, states[0] = 20.353774, states[40]= 0.009947
Saving checkpoint... 
Iteration: 1683175810, states[0] = -95.146714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696804011, states[0] = 32.739914, states[40]= 0.131355
Saving checkpoint... 
Iteration: 1710097851, states[0] = -36.012371, states[40]= 0.000226
Saving checkpoint... 
Iteration: 1723680374, states[0] = -95.157651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737360654, states[0] = 1.020007, states[40]= 0.004934
Saving checkpoint... 
Iteration: 1751124374, states[0] = 19.276445, states[40]= 0.008388
Saving checkpoint... 
Iteration: 1764458216, states[0] = -95.094275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1778013557, states[0] = -95.222576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791384966, states[0] = -21.870481, states[40]= 0.000899
Saving checkpoint... 
Iteration: 1804764784, states[0] = -94.983884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818268876, states[0] = -94.976238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831852881, states[0] = -95.024460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844003855, states[0] = 32.077461, states[40]= 0.158267
Saving checkpoint... 
Iteration: 1848067047, states[0] = 3.887026, states[40]= 0.004650
Saving checkpoint... 
Iteration: 1861258511, states[0] = -94.936610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874704482, states[0] = -94.848218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887709281, states[0] = -94.854999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900773677, states[0] = -94.945192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914569420, states[0] = 3.081992, states[40]= 0.004574
Saving checkpoint... 
Iteration: 1928154111, states[0] = -80.159751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941520398, states[0] = 21.066003, states[40]= 0.009280
Saving checkpoint... 
Iteration: 1954691638, states[0] = -94.814391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967978573, states[0] = -95.031704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981295367, states[0] = -94.961628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995071862, states[0] = 1.895092, states[40]= 0.004463
Saving checkpoint... 
Iteration: 2008979201, states[0] = -95.031423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022623625, states[0] = -42.575716, states[40]= 0.000088
Saving checkpoint... 
Iteration: 2036062371, states[0] = 6.422131, states[40]= 0.004784
Saving checkpoint... 
Iteration: 2049729041, states[0] = -94.884132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063234838, states[0] = -94.893100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076820427, states[0] = -94.979312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088344004, states[0] = -94.992670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098810723, states[0] = -94.972822, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909783
 - CaMKt in component CaMK (millimolar): 0.006977
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.548773
 - nass in component intracellular_ions (millimolar): 6.548833
 - ki in component intracellular_ions (millimolar): 145.428677
 - kss in component intracellular_ions (millimolar): 145.428658
 - cansr in component intracellular_ions (millimolar): 1.312048
 - cajsr in component intracellular_ions (millimolar): 1.274098
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880138
 - hs in component INa (dimensionless): 0.880134
 - j in component INa (dimensionless): 0.880105
 - hsp in component INa (dimensionless): 0.726089
 - jp in component INa (dimensionless): 0.880085
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710184
 - hLp in component INaL (dimensionless): 0.452409
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621648
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696638
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935741
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001602
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328604
 - xs1 in component IKs (dimensionless): 0.240664
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:54:29 (13032): called boinc_finish(0)

</stderr_txt>
]]>


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