𝕏

Task 55810617

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-CLVPET-conf_464_1
Workunit 26503441
Created 2 Jul 2024, 14:26:38 UTC
Sent 3 Jul 2024, 2:44:02 UTC
Report deadline 6 Jul 2024, 5:36:50 UTC
Received 3 Jul 2024, 15:33:50 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218427
Run time 2 hours 10 min 19 sec
CPU time 2 hours 5 min 11 sec
Validate state Valid
Credit 48.29
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.75 MB
Peak swap size 32.57 GB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-CLVPET-conf_464.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-CLVPET-conf_464_1_r1592787536_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-CLVPET-conf_464_1_r1592787536_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.898883
     * GNaL_b in INaL: 0.005817
     * Gto_b in Ito: 0.082737
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032258
     * GKs_b in IKs: 0.001956
     * GK1_b in IK1: 0.160934
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.827336
     * GKb_b in IKb: 0.003778
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033810
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13362619, states[0] = -94.866183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26825524, states[0] = -94.795035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40229183, states[0] = -94.584543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53615685, states[0] = -28.773788, states[40]= 0.001021
Saving checkpoint... 
Iteration: 66923706, states[0] = -94.851191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80503483, states[0] = 36.159924, states[40]= 0.396850
Saving checkpoint... 
Iteration: 94112877, states[0] = -25.895985, states[40]= 0.001139
Saving checkpoint... 
Iteration: 107342023, states[0] = -94.793977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120915987, states[0] = -94.845182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134523990, states[0] = 26.348260, states[40]= 0.001911
Saving checkpoint... 
Iteration: 148171638, states[0] = -92.501309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161519979, states[0] = 27.192710, states[40]= 0.002969
Saving checkpoint... 
Iteration: 175185375, states[0] = -94.362806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188949703, states[0] = -94.857773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202499103, states[0] = -94.870482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216152122, states[0] = -66.788475, states[40]= 0.000006
Saving checkpoint... 
Iteration: 229488632, states[0] = -94.868172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243087018, states[0] = -1.589870, states[40]= 0.004420
Saving checkpoint... 
Iteration: 256614661, states[0] = -27.565133, states[40]= 0.001083
Saving checkpoint... 
Iteration: 270246218, states[0] = -94.626222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283859415, states[0] = -94.808308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297487382, states[0] = -94.867619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311128194, states[0] = -40.812988, states[40]= 0.000319
Saving checkpoint... 
Iteration: 324796898, states[0] = -94.734824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338470683, states[0] = -94.863382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352094653, states[0] = -7.918344, states[40]= 0.003171
Saving checkpoint... 
Iteration: 365322130, states[0] = -94.770164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378596579, states[0] = -9.727185, states[40]= 0.002753
Saving checkpoint... 
Iteration: 392069682, states[0] = 8.777368, states[40]= 0.004475
Saving checkpoint... 
Iteration: 405687925, states[0] = -94.390943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419324157, states[0] = -94.772417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432998694, states[0] = -94.869481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446635939, states[0] = -48.809808, states[40]= 0.000106
Saving checkpoint... 
Iteration: 460260897, states[0] = -94.663461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473937015, states[0] = -94.852134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487257861, states[0] = -94.656000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500545578, states[0] = 19.183168, states[40]= 0.002680
Saving checkpoint... 
Iteration: 514133497, states[0] = -46.246894, states[40]= 0.000153
Saving checkpoint... 
Iteration: 527681922, states[0] = -94.285972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541349864, states[0] = -94.798989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554730375, states[0] = -94.576733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568232092, states[0] = -94.582330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581907448, states[0] = -94.838715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595524176, states[0] = 26.306896, states[40]= 0.001894
Saving checkpoint... 
Iteration: 609148457, states[0] = -62.427923, states[40]= 0.000012
Saving checkpoint... 
Iteration: 622470736, states[0] = -94.862323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636104035, states[0] = -17.120979, states[40]= 0.001492
Saving checkpoint... 
Iteration: 649671078, states[0] = -92.186168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663183539, states[0] = -94.328201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676562265, states[0] = 12.292838, states[40]= 0.003996
Saving checkpoint... 
Iteration: 690161182, states[0] = -79.711124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703621157, states[0] = -33.861409, states[40]= 0.000705
Saving checkpoint... 
Iteration: 717251982, states[0] = -94.640153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730572069, states[0] = 7.559062, states[40]= 0.004591
Saving checkpoint... 
Iteration: 743878631, states[0] = -94.821054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757450709, states[0] = -94.855882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770836029, states[0] = -94.784474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784079519, states[0] = 3.393627, states[40]= 0.004763
Saving checkpoint... 
Iteration: 797430028, states[0] = -94.848179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810882903, states[0] = -94.823653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824354242, states[0] = -94.801841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837738540, states[0] = -94.601618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851063334, states[0] = 11.808647, states[40]= 0.004073
Saving checkpoint... 
Iteration: 864615369, states[0] = -28.247853, states[40]= 0.001053
Saving checkpoint... 
Iteration: 877836455, states[0] = -94.784518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891413662, states[0] = -94.840612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905042346, states[0] = 20.407012, states[40]= 0.002449
Saving checkpoint... 
Iteration: 918572434, states[0] = 7.368618, states[40]= 0.004607
Saving checkpoint... 
Iteration: 932111206, states[0] = -24.209939, states[40]= 0.001178
Saving checkpoint... 
Iteration: 945397733, states[0] = -94.832140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958994815, states[0] = -94.866712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972244728, states[0] = -94.619326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986001173, states[0] = 48.162472, states[40]= 0.218512
Saving checkpoint... 
Iteration: 999566876, states[0] = 10.152760, states[40]= 0.004312
Saving checkpoint... 
Iteration: 1012986623, states[0] = -94.864743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026580547, states[0] = 2.766707, states[40]= 0.004755
Saving checkpoint... 
Iteration: 1040191512, states[0] = -94.414913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053657539, states[0] = -74.054419, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1067314234, states[0] = -94.757401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080968582, states[0] = -94.860010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094608409, states[0] = -21.471005, states[40]= 0.001234
Saving checkpoint... 
Iteration: 1108271775, states[0] = -94.685422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121965103, states[0] = -94.858890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135039395, states[0] = 21.494829, states[40]= 0.002255
Saving checkpoint... 
Iteration: 1148452922, states[0] = -94.855122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162111973, states[0] = -24.955320, states[40]= 0.001163
Saving checkpoint... 
Iteration: 1175647882, states[0] = -61.767377, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1189308050, states[0] = -94.748415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202949299, states[0] = -94.853733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216572039, states[0] = 7.575447, states[40]= 0.004590
Saving checkpoint... 
Iteration: 1230136095, states[0] = -48.970859, states[40]= 0.000103
Saving checkpoint... 
Iteration: 1243799527, states[0] = -94.735493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257388988, states[0] = -94.825819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270761732, states[0] = -94.662351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284400776, states[0] = -94.832542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298076141, states[0] = 5.359084, states[40]= 0.004728
Saving checkpoint... 
Iteration: 1311643231, states[0] = -56.610768, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1325088271, states[0] = -2.527996, states[40]= 0.004282
Saving checkpoint... 
Iteration: 1338697638, states[0] = -94.445593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352070713, states[0] = 8.258317, states[40]= 0.004528
Saving checkpoint... 
Iteration: 1365593894, states[0] = -7.223145, states[40]= 0.003332
Saving checkpoint... 
Iteration: 1379201322, states[0] = -94.462069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392857641, states[0] = -94.802615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406211940, states[0] = -94.506265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419749861, states[0] = -94.631828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433408406, states[0] = -94.835980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446686694, states[0] = -94.374389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460211776, states[0] = -94.505406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473845235, states[0] = -94.791106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487458744, states[0] = -94.855652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501098354, states[0] = 7.745438, states[40]= 0.007965
Saving checkpoint... 
Iteration: 1514562321, states[0] = 6.190682, states[40]= 0.006388
Saving checkpoint... 
Iteration: 1527497676, states[0] = -94.620241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540606838, states[0] = -94.751479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553594089, states[0] = -3.595325, states[40]= 0.003886
Saving checkpoint... 
Iteration: 1566465455, states[0] = -94.610943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579534708, states[0] = -94.614169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592565484, states[0] = -94.522260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605616613, states[0] = -15.399876, states[40]= 0.001620
Saving checkpoint... 
Iteration: 1618526277, states[0] = -94.451628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631622705, states[0] = -94.425398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644728431, states[0] = -94.410736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657536637, states[0] = 24.349796, states[40]= 0.002041
Saving checkpoint... 
Iteration: 1670698991, states[0] = -94.416675, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.271422
 - CaMKt in component CaMK (millimolar): 0.001123
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.390860
 - nass in component intracellular_ions (millimolar): 6.390946
 - ki in component intracellular_ions (millimolar): 145.507134
 - kss in component intracellular_ions (millimolar): 145.507123
 - cansr in component intracellular_ions (millimolar): 1.566559
 - cajsr in component intracellular_ions (millimolar): 1.566579
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003856
 - hf in component INa (dimensionless): 0.868623
 - hs in component INa (dimensionless): 0.868623
 - j in component INa (dimensionless): 0.868624
 - hsp in component INa (dimensionless): 0.704768
 - jp in component INa (dimensionless): 0.868625
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.712232
 - hLp in component INaL (dimensionless): 0.519489
 - a in component Ito (dimensionless): 0.000651
 - iF in component Ito (dimensionless): 0.999854
 - iS in component Ito (dimensionless): 0.997754
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999854
 - iSp in component Ito (dimensionless): 0.999254
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998884
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003002
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001802
 - xs1 in component IKs (dimensionless): 0.022479
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997498
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:28:32 (23574): called boinc_finish(0)

</stderr_txt>
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