𝕏

Task 55800349

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_548_0
Workunit 26498309
Created 2 Jul 2024, 14:21:57 UTC
Sent 3 Jul 2024, 1:42:35 UTC
Report deadline 6 Jul 2024, 1:42:35 UTC
Received 3 Jul 2024, 17:48:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217636
Run time 1 hours 51 min 39 sec
CPU time 1 hours 14 min 39 sec
Validate state Valid
Credit 53.70
Device peak FLOPS 4.26 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.38 MB
Peak swap size 5.33 MB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_548.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_548_0_r617374735_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_548_0_r617374735_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.632363
     * GNaL_b in INaL: 0.005664
     * Gto_b in Ito: 0.081690
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031414
     * GKs_b in IKs: 0.001909
     * GK1_b in IK1: 0.164632
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.563190
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031976
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12444026, states[0] = -94.768783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27458087, states[0] = -94.704378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43770346, states[0] = -94.712521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59312606, states[0] = -94.533552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69776150, states[0] = -94.693092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85262426, states[0] = -94.414892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100555608, states[0] = -94.671288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116028199, states[0] = 25.730193, states[40]= 0.001718
Saving checkpoint... 
Iteration: 129611909, states[0] = -94.674442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142060613, states[0] = 16.179261, states[40]= 0.003393
Saving checkpoint... 
Iteration: 157399077, states[0] = -94.607851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171488456, states[0] = -94.650088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185608106, states[0] = -94.671555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198276697, states[0] = -94.440708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212693776, states[0] = -94.676102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224818186, states[0] = -94.676740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243328576, states[0] = -94.535315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258969060, states[0] = -94.673554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274228978, states[0] = -94.297689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289244867, states[0] = -94.351957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297827275, states[0] = -94.676288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300759618, states[0] = -94.676634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304045260, states[0] = 21.277108, states[40]= 0.002394
Saving checkpoint... 
Iteration: 308125905, states[0] = -24.175958, states[40]= 0.001391
Saving checkpoint... 
Iteration: 313160665, states[0] = -54.915126, states[40]= 0.000044
Saving checkpoint... 
Iteration: 321593003, states[0] = -94.669084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329762189, states[0] = -94.676571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337089661, states[0] = 3.501508, states[40]= 0.004589
Saving checkpoint... 
Iteration: 344863870, states[0] = -94.675628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350324511, states[0] = -94.529190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355677331, states[0] = -94.674944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363329425, states[0] = -94.536127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370787562, states[0] = -94.676461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377744806, states[0] = -94.676382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384238118, states[0] = -94.329488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390384147, states[0] = -94.594628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398094949, states[0] = 0.484950, states[40]= 0.004442
Saving checkpoint... 
Iteration: 406015431, states[0] = 27.233561, states[40]= 0.008735
Saving checkpoint... 
Iteration: 410488879, states[0] = -94.648755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417079217, states[0] = 8.686743, states[40]= 0.004417
Saving checkpoint... 
Iteration: 423687947, states[0] = -94.675192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430187023, states[0] = -87.371118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435343082, states[0] = -94.553650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441403623, states[0] = -94.608974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452851217, states[0] = -94.675633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468414639, states[0] = -94.615993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476690498, states[0] = -94.675176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486810090, states[0] = -94.676093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502117833, states[0] = -17.270089, states[40]= 0.001463
Saving checkpoint... 
Iteration: 518693974, states[0] = -94.675205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533244612, states[0] = -94.350641, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_548.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_548_0_r617374735_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_2000-conf_548_0_r617374735_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.632363
     * GNaL_b in INaL: 0.005664
     * Gto_b in Ito: 0.081690
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031414
     * GKs_b in IKs: 0.001909
     * GK1_b in IK1: 0.164632
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.563190
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031976
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 533244612
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.350641 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 536576373, states[0] = -94.666672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546868690, states[0] = -94.675164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563318083, states[0] = -94.519149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571959924, states[0] = -94.673111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590321187, states[0] = -94.523833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605560350, states[0] = -94.664267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620090904, states[0] = 2.821674, states[40]= 0.004574
Saving checkpoint... 
Iteration: 637676360, states[0] = -94.674385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641393583, states[0] = -94.601496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647989917, states[0] = -94.672211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654967483, states[0] = -94.672771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670933239, states[0] = -94.673577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672961836, states[0] = -94.672880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690973497, states[0] = -94.672554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708392611, states[0] = -94.600648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725832553, states[0] = -94.675406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732052559, states[0] = 18.974024, states[40]= 0.002855
Saving checkpoint... 
Iteration: 747841923, states[0] = -94.675236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765323694, states[0] = -94.527229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782418471, states[0] = -94.617712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793923789, states[0] = -94.673573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800751525, states[0] = -94.675654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818340273, states[0] = -94.549507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835533595, states[0] = -94.659132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851993886, states[0] = -94.671737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855466338, states[0] = -94.640281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868853260, states[0] = -94.674842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883976478, states[0] = -94.672126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903466755, states[0] = -94.640350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917932092, states[0] = -94.673154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925976643, states[0] = -94.672046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935544824, states[0] = -94.661080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938316645, states[0] = -94.516217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942193734, states[0] = -92.843680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943512073, states[0] = -94.654152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950461967, states[0] = -94.638427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956984723, states[0] = -94.671782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964813984, states[0] = -94.675185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969776089, states[0] = -94.675398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975240662, states[0] = -94.336925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981962248, states[0] = -94.672307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988645048, states[0] = -94.672198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994321817, states[0] = -94.524035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998880901, states[0] = -94.674112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004271514, states[0] = -94.426168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011527400, states[0] = -94.657534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016669656, states[0] = -94.673418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022135882, states[0] = -32.571766, states[40]= 0.000950
Saving checkpoint... 
Iteration: 1030041684, states[0] = 22.342579, states[40]= 0.002195
Saving checkpoint... 
Iteration: 1037197181, states[0] = -93.683047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043549220, states[0] = -94.661656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048248903, states[0] = -94.363208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054646791, states[0] = -94.672183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061422060, states[0] = -94.619277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064990995, states[0] = -94.671424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072542562, states[0] = -94.660420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078743073, states[0] = -94.675087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084473807, states[0] = -94.642582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090121467, states[0] = -20.411217, states[40]= 0.001361
Saving checkpoint... 
Iteration: 1097223213, states[0] = -94.274746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102762921, states[0] = -94.675150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109860229, states[0] = -94.674288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114713011, states[0] = -94.674593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120097188, states[0] = -0.900885, states[40]= 0.004301
Saving checkpoint... 
Iteration: 1125475113, states[0] = -94.642964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131997342, states[0] = -94.671137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133992057, states[0] = -94.671271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137524750, states[0] = -94.656734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140709183, states[0] = -94.674464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145762653, states[0] = -94.675071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147782496, states[0] = -94.675060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148921198, states[0] = -94.672985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166605335, states[0] = -94.668798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183919045, states[0] = -94.672971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200766514, states[0] = -94.674978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216786834, states[0] = -94.674919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233425339, states[0] = -94.620799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250592606, states[0] = -94.667329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267435041, states[0] = -94.625850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284989770, states[0] = -94.671055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302360408, states[0] = -94.571313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319103476, states[0] = -5.238606, states[40]= 0.003578
Saving checkpoint... 
Iteration: 1335731996, states[0] = -94.674502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352564074, states[0] = -94.663470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369497379, states[0] = -94.649503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386586450, states[0] = -94.666378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403123572, states[0] = -22.203949, states[40]= 0.001372
Saving checkpoint... 
Iteration: 1420570521, states[0] = -94.664272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437633453, states[0] = -94.670627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454114533, states[0] = -14.383494, states[40]= 0.001756
Saving checkpoint... 
Iteration: 1470530601, states[0] = -94.657368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486834113, states[0] = -94.674000, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.546335
 - CaMKt in component CaMK (millimolar): 0.004195
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.443956
 - nass in component intracellular_ions (millimolar): 6.444041
 - ki in component intracellular_ions (millimolar): 145.468904
 - kss in component intracellular_ions (millimolar): 145.468889
 - cansr in component intracellular_ions (millimolar): 1.587650
 - cajsr in component intracellular_ions (millimolar): 1.586932
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003751
 - hf in component INa (dimensionless): 0.873693
 - hs in component INa (dimensionless): 0.873694
 - j in component INa (dimensionless): 0.873700
 - hsp in component INa (dimensionless): 0.714085
 - jp in component INa (dimensionless): 0.873703
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.719543
 - hLp in component INaL (dimensionless): 0.511454
 - a in component Ito (dimensionless): 0.000639
 - iF in component Ito (dimensionless): 0.999861
 - iS in component Ito (dimensionless): 0.891734
 - ap in component Ito (dimensionless): 0.000325
 - iFp in component Ito (dimensionless): 0.999861
 - iSp in component Ito (dimensionless): 0.931547
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975325
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002699
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.098159
 - xs1 in component IKs (dimensionless): 0.125692
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997429
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:47:44 (22452): called boinc_finish(0)

</stderr_txt>
]]>


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