𝕏

Task 55799500

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_1000-conf_746_1
Workunit 26497886
Created 2 Jul 2024, 14:21:35 UTC
Sent 3 Jul 2024, 1:35:13 UTC
Report deadline 6 Jul 2024, 1:35:13 UTC
Received 3 Jul 2024, 17:08:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230398
Run time 2 hours 7 min 11 sec
CPU time 2 hours 5 min 21 sec
Validate state Valid
Credit 42.83
Device peak FLOPS 3.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.88 MB
Peak swap size 4.10 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_1000-conf_746.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_1000-conf_746_1_r1731361502_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_1000-conf_746_1_r1731361502_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.325444
     * GNaL_b in INaL: 0.006034
     * Gto_b in Ito: 0.086335
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031847
     * GKs_b in IKs: 0.001899
     * GK1_b in IK1: 0.164107
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256951
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031984
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12042625, states[0] = 22.670271, states[40]= 0.000059
Saving checkpoint... 
Iteration: 23172875, states[0] = -82.836490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33910035, states[0] = -84.475666, states[40]= 0.000001
Saving checkpoint... 
Iteration: 45244352, states[0] = -84.093614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56077340, states[0] = 6.818543, states[40]= 0.000226
Saving checkpoint... 
Iteration: 65844855, states[0] = -84.380623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 75873349, states[0] = -84.417102, states[40]= 0.000001
Saving checkpoint... 
Iteration: 86137855, states[0] = -46.698463, states[40]= 0.000051
Saving checkpoint... 
Iteration: 96960688, states[0] = -84.480405, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_1000-conf_746.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_1000-conf_746_1_r1731361502_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_1000-conf_746_1_r1731361502_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.325444
     * GNaL_b in INaL: 0.006034
     * Gto_b in Ito: 0.086335
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031847
     * GKs_b in IKs: 0.001899
     * GK1_b in IK1: 0.164107
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256951
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031984
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 96960688
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.480405 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 109029590, states[0] = 28.500101, states[40]= 0.000066


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_1000-conf_746.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_1000-conf_746_1_r1731361502_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_1000-conf_746_1_r1731361502_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.325444
     * GNaL_b in INaL: 0.006034
     * Gto_b in Ito: 0.086335
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031847
     * GKs_b in IKs: 0.001899
     * GK1_b in IK1: 0.164107
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256951
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031984
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 109029590
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 28.500101 (After loading)
 - states[40]: 0.000066 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 121170031, states[0] = -80.900972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133301377, states[0] = -84.280472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 145476135, states[0] = -84.483194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 157556254, states[0] = 17.474330, states[40]= 0.000055
Saving checkpoint... 
Iteration: 169691009, states[0] = -83.715955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181837398, states[0] = -84.356063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 194016686, states[0] = 31.419125, states[40]= 0.005546
Saving checkpoint... 
Iteration: 206138155, states[0] = -46.717468, states[40]= 0.000052
Saving checkpoint... 
Iteration: 218351689, states[0] = -84.378514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 230455339, states[0] = -84.472057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 242633185, states[0] = -41.755035, states[40]= 0.000095
Saving checkpoint... 
Iteration: 254822808, states[0] = -84.327173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 266938429, states[0] = -84.462380, states[40]= 0.000001
Saving checkpoint... 
Iteration: 279048461, states[0] = 21.002049, states[40]= 0.000030
Saving checkpoint... 
Iteration: 291326622, states[0] = -84.334337, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303535506, states[0] = 26.383755, states[40]= 0.000018
Saving checkpoint... 
Iteration: 315667020, states[0] = -78.624423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327805646, states[0] = -84.287397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 339965529, states[0] = -84.475330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 352200289, states[0] = -83.795739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364362407, states[0] = -84.391662, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376561884, states[0] = 14.831794, states[40]= 0.000082
Saving checkpoint... 
Iteration: 388715415, states[0] = -83.901421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401047933, states[0] = 21.234798, states[40]= 0.000029
Saving checkpoint... 
Iteration: 413221789, states[0] = -83.941783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425345409, states[0] = -84.365987, states[40]= 0.000001
Saving checkpoint... 
Iteration: 437493838, states[0] = -84.484772, states[40]= 0.000001
Saving checkpoint... 
Iteration: 449709061, states[0] = -83.857769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461847824, states[0] = -84.369331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 474065917, states[0] = 12.878571, states[40]= 0.000110
Saving checkpoint... 
Iteration: 486175199, states[0] = -82.759173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498230182, states[0] = -83.990684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510196959, states[0] = -83.767309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522377774, states[0] = -84.408499, states[40]= 0.000001
Saving checkpoint... 
Iteration: 534465338, states[0] = -84.472725, states[40]= 0.000001
Saving checkpoint... 
Iteration: 546589296, states[0] = 0.063213, states[40]= 0.000431
Saving checkpoint... 
Iteration: 558701040, states[0] = -83.798629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570798431, states[0] = -84.265545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582981438, states[0] = -84.478617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 595084389, states[0] = 3.111737, states[40]= 0.000345
Saving checkpoint... 
Iteration: 607170218, states[0] = -80.927384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619293664, states[0] = -84.251723, states[40]= 0.000001
Saving checkpoint... 
Iteration: 631385406, states[0] = -84.415374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 643433357, states[0] = -84.454389, states[40]= 0.000001
Saving checkpoint... 
Iteration: 655573112, states[0] = 9.269646, states[40]= 0.000177
Saving checkpoint... 
Iteration: 667630304, states[0] = -38.894627, states[40]= 0.000130
Saving checkpoint... 
Iteration: 679661419, states[0] = -72.476175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 691732082, states[0] = -83.998863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703883374, states[0] = -84.412290, states[40]= 0.000001
Saving checkpoint... 
Iteration: 715898893, states[0] = -84.427380, states[40]= 0.000001
Saving checkpoint... 
Iteration: 727977602, states[0] = -84.475292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 740085652, states[0] = 2.359677, states[40]= 0.000367
Saving checkpoint... 
Iteration: 752345774, states[0] = -84.362306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 764385214, states[0] = -84.413445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 776477635, states[0] = -84.474677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 788549687, states[0] = 20.462776, states[40]= 0.000033
Saving checkpoint... 
Iteration: 800636239, states[0] = -44.777789, states[40]= 0.000066
Saving checkpoint... 
Iteration: 812715861, states[0] = -83.898638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824831551, states[0] = -84.336796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 836938423, states[0] = -84.454968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 849013783, states[0] = 31.368373, states[40]= 0.015450
Saving checkpoint... 
Iteration: 861178000, states[0] = -83.193618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873244707, states[0] = -84.062853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885403000, states[0] = -84.428811, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897532230, states[0] = 27.606274, states[40]= 0.000032
Saving checkpoint... 
Iteration: 909669434, states[0] = -80.443614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921762177, states[0] = -84.140339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933991988, states[0] = -84.477749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 946040575, states[0] = 24.368832, states[40]= 0.000017
Saving checkpoint... 
Iteration: 958179030, states[0] = -83.296705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970290998, states[0] = -84.239418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982409040, states[0] = -84.432613, states[40]= 0.000001
Saving checkpoint... 
Iteration: 994621920, states[0] = -30.607363, states[40]= 0.000248
Saving checkpoint... 
Iteration: 1006806844, states[0] = -84.281444, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018884021, states[0] = -84.408882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1030999619, states[0] = -84.478887, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1043240748, states[0] = -84.040705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055357083, states[0] = -84.375352, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1067556478, states[0] = 17.382145, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1079662048, states[0] = -73.224736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1091758380, states[0] = -84.122367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103901599, states[0] = -84.424753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1116000521, states[0] = 22.119649, states[40]= 0.017695
Saving checkpoint... 
Iteration: 1128004416, states[0] = 30.371910, states[40]= 0.416441
Saving checkpoint... 
Iteration: 1139151574, states[0] = -60.688523, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1151260115, states[0] = -84.128844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163425951, states[0] = -84.442823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1175495188, states[0] = -84.475654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1187630998, states[0] = -39.568716, states[40]= 0.000121
Saving checkpoint... 
Iteration: 1199715465, states[0] = -83.890834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211841740, states[0] = -84.349725, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1223930236, states[0] = -84.444877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1236007944, states[0] = 29.922828, states[40]= 0.121413
Saving checkpoint... 
Iteration: 1248058070, states[0] = 16.641753, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1260172529, states[0] = -81.978987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272309803, states[0] = -84.285099, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1284484859, states[0] = -84.470779, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1296532128, states[0] = 27.644935, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1308627752, states[0] = -36.363940, states[40]= 0.000166
Saving checkpoint... 
Iteration: 1320787304, states[0] = -84.223759, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332877708, states[0] = -84.397884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1345006160, states[0] = 29.560897, states[40]= 0.227029
Saving checkpoint... 
Iteration: 1357013698, states[0] = 31.362289, states[40]= 0.015919
Saving checkpoint... 
Iteration: 1369030513, states[0] = 28.213346, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1381213018, states[0] = -83.872159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393374765, states[0] = -84.393710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1405511480, states[0] = 31.000616, states[40]= 0.034859
Saving checkpoint... 
Iteration: 1417583254, states[0] = 3.781033, states[40]= 0.000324
Saving checkpoint... 
Iteration: 1429785186, states[0] = -84.215778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1441857373, states[0] = -84.370725, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1454043632, states[0] = 23.095137, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1466113755, states[0] = -22.423945, states[40]= 0.000273
Saving checkpoint... 
Iteration: 1478124418, states[0] = -33.069888, states[40]= 0.000215
Saving checkpoint... 
Iteration: 1490191462, states[0] = -83.702364, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.348809
 - CaMKt in component CaMK (millimolar): 0.016815
 - cass in component intracellular_ions (millimolar): 0.000091
 - nai in component intracellular_ions (millimolar): 6.613557
 - nass in component intracellular_ions (millimolar): 6.613677
 - ki in component intracellular_ions (millimolar): 145.170906
 - kss in component intracellular_ions (millimolar): 145.170882
 - cansr in component intracellular_ions (millimolar): 1.804098
 - cajsr in component intracellular_ions (millimolar): 1.750076
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.010467
 - hf in component INa (dimensionless): 0.564255
 - hs in component INa (dimensionless): 0.564222
 - j in component INa (dimensionless): 0.564051
 - hsp in component INa (dimensionless): 0.318492
 - jp in component INa (dimensionless): 0.563928
 - mL in component INaL (dimensionless): 0.000368
 - hL in component INaL (dimensionless): 0.382927
 - hLp in component INaL (dimensionless): 0.181642
 - a in component Ito (dimensionless): 0.001270
 - iF in component Ito (dimensionless): 0.999173
 - iS in component Ito (dimensionless): 0.549162
 - ap in component Ito (dimensionless): 0.000647
 - iFp in component Ito (dimensionless): 0.999173
 - iSp in component Ito (dimensionless): 0.589384
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.907876
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999802
 - jca in component ICaL (dimensionless): 0.999970
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003573
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.507533
 - xs1 in component IKs (dimensionless): 0.281822
 - xs2 in component IKs (dimensionless): 0.000286
 - xk1 in component IK1 (dimensionless): 0.996836
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
17:07:40 (68385): called boinc_finish(0)

</stderr_txt>
]]>


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