𝕏

Task 55799451

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_500-conf_146_0
Workunit 26497862
Created 2 Jul 2024, 14:21:35 UTC
Sent 3 Jul 2024, 1:35:13 UTC
Report deadline 6 Jul 2024, 1:35:13 UTC
Received 3 Jul 2024, 17:08:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230398
Run time 2 hours 5 min 23 sec
CPU time 2 hours 4 min 12 sec
Validate state Valid
Credit 43.92
Device peak FLOPS 3.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.80 MB
Peak swap size 4.10 GB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_500-conf_146.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_500-conf_146_0_r791434167_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_500-conf_146_0_r791434167_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.703147
     * GNaL_b in INaL: 0.005859
     * Gto_b in Ito: 0.083853
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032273
     * GKs_b in IKs: 0.001956
     * GK1_b in IK1: 0.159823
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.919851
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034056
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12274206, states[0] = 18.676296, states[40]= 0.008361
Saving checkpoint... 
Iteration: 24568919, states[0] = -12.315009, states[40]= 0.002237
Saving checkpoint... 
Iteration: 36897521, states[0] = -87.241257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49243145, states[0] = -87.437582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61536568, states[0] = 13.217541, states[40]= 0.006329
Saving checkpoint... 
Iteration: 73746157, states[0] = -87.432530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86076523, states[0] = -20.556061, states[40]= 0.001019
Saving checkpoint... 
Iteration: 98198459, states[0] = -87.356120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110428068, states[0] = -87.310052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122689510, states[0] = -87.335916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134907410, states[0] = -87.252516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147101542, states[0] = -51.261380, states[40]= 0.000023
Saving checkpoint... 
Iteration: 159259810, states[0] = 23.722400, states[40]= 0.048544
Saving checkpoint... 
Iteration: 171409242, states[0] = -87.257421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183642384, states[0] = -87.179701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195814443, states[0] = -6.213332, states[40]= 0.003686
Saving checkpoint... 
Iteration: 208030670, states[0] = 16.341632, states[40]= 0.006868
Saving checkpoint... 
Iteration: 220268733, states[0] = 21.248306, states[40]= 0.011411
Saving checkpoint... 
Iteration: 232506086, states[0] = 26.045000, states[40]= 0.105533
Saving checkpoint... 
Iteration: 244749789, states[0] = -87.429987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257042433, states[0] = 10.039636, states[40]= 0.005989
Saving checkpoint... 
Iteration: 269296468, states[0] = 7.621093, states[40]= 0.005789
Saving checkpoint... 
Iteration: 281501104, states[0] = 41.850923, states[40]= 0.035953
Saving checkpoint... 
Iteration: 293705885, states[0] = -87.367134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305872064, states[0] = -80.604171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318102948, states[0] = -53.048255, states[40]= 0.000018
Saving checkpoint... 
Iteration: 330352002, states[0] = -51.826958, states[40]= 0.000021
Saving checkpoint... 
Iteration: 342525294, states[0] = 18.787973, states[40]= 0.007824
Saving checkpoint... 
Iteration: 354779938, states[0] = 16.694329, states[40]= 0.006961
Saving checkpoint... 
Iteration: 366926344, states[0] = -87.303624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379094674, states[0] = -42.596438, states[40]= 0.000088
Saving checkpoint... 
Iteration: 391265346, states[0] = 22.250006, states[40]= 0.017074
Saving checkpoint... 
Iteration: 403507472, states[0] = 24.810029, states[40]= 0.080600
Saving checkpoint... 
Iteration: 415730495, states[0] = -87.406007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428011839, states[0] = 23.145995, states[40]= 0.031644
Saving checkpoint... 
Iteration: 440182531, states[0] = -87.318555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452418735, states[0] = -87.283759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464667773, states[0] = -87.281140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476816721, states[0] = -8.632138, states[40]= 0.003090
Saving checkpoint... 
Iteration: 489049344, states[0] = 5.804099, states[40]= 0.005639
Saving checkpoint... 
Iteration: 501176725, states[0] = -87.304444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513372626, states[0] = -81.292758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525681265, states[0] = -87.315479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537905937, states[0] = -87.246727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550096446, states[0] = -44.793823, states[40]= 0.000063
Saving checkpoint... 
Iteration: 562314617, states[0] = -6.388303, states[40]= 0.003643
Saving checkpoint... 
Iteration: 574527935, states[0] = 17.628251, states[40]= 0.007264
Saving checkpoint... 
Iteration: 586749224, states[0] = -87.429008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598939846, states[0] = -87.334923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611063849, states[0] = -5.609927, states[40]= 0.003832
Saving checkpoint... 
Iteration: 623280222, states[0] = 16.558533, states[40]= 0.006924
Saving checkpoint... 
Iteration: 635539192, states[0] = 11.886324, states[40]= 0.006164
Saving checkpoint... 
Iteration: 647616611, states[0] = -72.482160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 659741845, states[0] = -87.420391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671853742, states[0] = -54.079047, states[40]= 0.000015
Saving checkpoint... 
Iteration: 684015450, states[0] = 22.221964, states[40]= 0.016816
Saving checkpoint... 
Iteration: 696169462, states[0] = -87.285474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708421108, states[0] = -87.289836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720626732, states[0] = -84.903660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732820727, states[0] = -13.276011, states[40]= 0.002043
Saving checkpoint... 
Iteration: 744504589, states[0] = 28.551662, states[40]= 0.128751
Saving checkpoint... 
Iteration: 756385412, states[0] = -86.984574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768602721, states[0] = -52.753558, states[40]= 0.000018
Saving checkpoint... 
Iteration: 780767939, states[0] = 21.500247, states[40]= 0.012336
Saving checkpoint... 
Iteration: 792983922, states[0] = -87.410255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805145555, states[0] = -87.204601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817308468, states[0] = -0.754042, states[40]= 0.004845
Saving checkpoint... 
Iteration: 829617416, states[0] = -73.755080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841800075, states[0] = 5.327907, states[40]= 0.005598
Saving checkpoint... 
Iteration: 854008156, states[0] = 24.406298, states[40]= 0.069674
Saving checkpoint... 
Iteration: 866230668, states[0] = -87.405806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878453727, states[0] = -87.362592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890625790, states[0] = -84.294998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902809626, states[0] = -1.717525, states[40]= 0.004673
Saving checkpoint... 
Iteration: 915108128, states[0] = -59.923760, states[40]= 0.000006
Saving checkpoint... 
Iteration: 927303155, states[0] = 3.243152, states[40]= 0.005394
Saving checkpoint... 
Iteration: 939479451, states[0] = -87.404055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951638485, states[0] = -87.111268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963776768, states[0] = 18.151428, states[40]= 0.007483
Saving checkpoint... 
Iteration: 975924726, states[0] = -87.298944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988062596, states[0] = -4.387625, states[40]= 0.004117
Saving checkpoint... 
Iteration: 1000245411, states[0] = -87.424279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012459743, states[0] = -87.373286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024648939, states[0] = -87.221479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036937574, states[0] = -87.329501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049095373, states[0] = -43.459870, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1061271942, states[0] = 20.127091, states[40]= 0.009045
Saving checkpoint... 
Iteration: 1073456628, states[0] = -87.367713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085460885, states[0] = -87.375187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097595807, states[0] = -43.998103, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1109832703, states[0] = -27.999363, states[40]= 0.000534
Saving checkpoint... 
Iteration: 1122106803, states[0] = -58.125628, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1134159560, states[0] = -87.257178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146324182, states[0] = -17.499747, states[40]= 0.001353
Saving checkpoint... 
Iteration: 1158502203, states[0] = 38.072727, states[40]= 0.096503
Saving checkpoint... 
Iteration: 1170605539, states[0] = -56.438670, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1182754462, states[0] = 28.853989, states[40]= 0.129895
Saving checkpoint... 
Iteration: 1194851277, states[0] = -50.894616, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1207007707, states[0] = 24.659954, states[40]= 0.076708
Saving checkpoint... 
Iteration: 1219130879, states[0] = -86.439011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231328365, states[0] = -22.669873, states[40]= 0.000848
Saving checkpoint... 
Iteration: 1243501392, states[0] = 41.846217, states[40]= 0.054637
Saving checkpoint... 
Iteration: 1255616162, states[0] = -71.771138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1267776113, states[0] = 18.437885, states[40]= 0.007625
Saving checkpoint... 
Iteration: 1279901405, states[0] = -87.230847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292138997, states[0] = -87.123778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304403467, states[0] = -87.237986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316610703, states[0] = -63.526264, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1328732430, states[0] = -87.407747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340874038, states[0] = -82.819573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353094492, states[0] = -42.370348, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1365295006, states[0] = 8.514428, states[40]= 0.005861
Saving checkpoint... 
Iteration: 1377453486, states[0] = -87.361656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389549077, states[0] = 5.977030, states[40]= 0.005654
Saving checkpoint... 
Iteration: 1401696505, states[0] = -87.348081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413819409, states[0] = -11.704618, states[40]= 0.002370
Saving checkpoint... 
Iteration: 1425952544, states[0] = -87.359841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438125253, states[0] = -83.890918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450267344, states[0] = 21.681984, states[40]= 0.013161
Saving checkpoint... 
Iteration: 1462452622, states[0] = -87.359953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474606343, states[0] = -57.508126, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1486824023, states[0] = -17.303054, states[40]= 0.001379
Saving checkpoint... 
Iteration: 1498969177, states[0] = -87.388367, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.304732
 - CaMKt in component CaMK (millimolar): 0.018951
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 6.726353
 - nass in component intracellular_ions (millimolar): 6.726453
 - ki in component intracellular_ions (millimolar): 145.233217
 - kss in component intracellular_ions (millimolar): 145.233191
 - cansr in component intracellular_ions (millimolar): 1.415783
 - cajsr in component intracellular_ions (millimolar): 1.200969
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007780
 - hf in component INa (dimensionless): 0.677904
 - hs in component INa (dimensionless): 0.677802
 - j in component INa (dimensionless): 0.677108
 - hsp in component INa (dimensionless): 0.431413
 - jp in component INa (dimensionless): 0.675215
 - mL in component INaL (dimensionless): 0.000210
 - hL in component INaL (dimensionless): 0.388169
 - hLp in component INaL (dimensionless): 0.182206
 - a in component Ito (dimensionless): 0.001041
 - iF in component Ito (dimensionless): 0.999507
 - iS in component Ito (dimensionless): 0.294748
 - ap in component Ito (dimensionless): 0.000530
 - iFp in component Ito (dimensionless): 0.999507
 - iSp in component Ito (dimensionless): 0.342884
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.859121
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991212
 - jca in component ICaL (dimensionless): 0.991563
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004127
 - xrf in component IKr (dimensionless): 0.001687
 - xrs in component IKr (dimensionless): 0.673177
 - xs1 in component IKs (dimensionless): 0.380975
 - xs2 in component IKs (dimensionless): 0.000214
 - xk1 in component IK1 (dimensionless): 0.996909
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:39:48 (68568): called boinc_finish(0)

</stderr_txt>
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