𝕏

Task 55799450

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_946_1
Workunit 26497861
Created 2 Jul 2024, 14:21:35 UTC
Sent 3 Jul 2024, 1:35:13 UTC
Report deadline 6 Jul 2024, 1:35:13 UTC
Received 3 Jul 2024, 15:11:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230398
Run time 2 hours 6 min 14 sec
CPU time 2 hours 4 min 18 sec
Validate state Valid
Credit 42.87
Device peak FLOPS 3.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.35 MB
Peak swap size 4.10 GB
Peak disk usage 1.25 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_946.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_946_1_r309863294_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_946_1_r309863294_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.714219
     * GNaL_b in INaL: 0.006214
     * Gto_b in Ito: 0.082436
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031775
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.161550
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.950884
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032937
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12257581, states[0] = -86.566898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24524261, states[0] = -86.634467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36751362, states[0] = -86.594801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49107770, states[0] = -86.555012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61382456, states[0] = -86.526147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73433015, states[0] = -86.508534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85609659, states[0] = -86.494093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97819442, states[0] = -86.483176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109986680, states[0] = -86.475445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122311479, states[0] = -86.382143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134558118, states[0] = -86.476101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146785662, states[0] = -86.481000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159134967, states[0] = -86.473091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171380551, states[0] = -86.467334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183531727, states[0] = -86.464182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195743335, states[0] = -86.461104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207874205, states[0] = -86.459409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220077824, states[0] = 7.778672, states[40]= 0.004171
Saving checkpoint... 
Iteration: 232368788, states[0] = -86.414337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243678255, states[0] = -86.460142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255015715, states[0] = -86.470491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265916014, states[0] = -86.457782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276874088, states[0] = -86.472907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287230454, states[0] = -86.465944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296911759, states[0] = -86.472150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307375868, states[0] = -86.463387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318153629, states[0] = -44.678477, states[40]= 0.000063


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_946.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_946_1_r309863294_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_946_1_r309863294_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.714219
     * GNaL_b in INaL: 0.006214
     * Gto_b in Ito: 0.082436
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031775
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.161550
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.950884
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032937
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 318153629
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -44.678477 (After loading)
 - states[40]: 0.000063 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 330202372, states[0] = -86.032077, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_946.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_946_1_r309863294_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_4000-conf_946_1_r309863294_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.714219
     * GNaL_b in INaL: 0.006214
     * Gto_b in Ito: 0.082436
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031775
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.161550
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.950884
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032937
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 330202372
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.032077 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 342355855, states[0] = -86.405359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354569631, states[0] = -86.467350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366850635, states[0] = -86.472946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379060343, states[0] = -86.469032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391239889, states[0] = -86.465518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403368276, states[0] = -86.463344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415585134, states[0] = -86.460402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427851482, states[0] = -86.457821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440021551, states[0] = 22.005054, states[40]= 0.007038
Saving checkpoint... 
Iteration: 452208843, states[0] = -86.193954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464484162, states[0] = -86.455289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476688363, states[0] = -86.473057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488877980, states[0] = -86.472484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501107769, states[0] = -86.468019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513185638, states[0] = -86.466485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525350932, states[0] = -86.463580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537571349, states[0] = -86.460529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549787155, states[0] = -86.458326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562073735, states[0] = 9.253050, states[40]= 0.004210
Saving checkpoint... 
Iteration: 574324752, states[0] = -86.381290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586466485, states[0] = -86.451335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598669784, states[0] = -86.472619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610865200, states[0] = -86.472655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623102502, states[0] = -86.468100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635178474, states[0] = -86.466598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647359736, states[0] = -86.463416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659590277, states[0] = -86.460284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671827458, states[0] = -86.457961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683983173, states[0] = -86.456807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696208510, states[0] = -86.190317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708317918, states[0] = -86.375008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720486373, states[0] = -86.455685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732686601, states[0] = -86.472972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744982820, states[0] = -86.470511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757138639, states[0] = -86.467352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769440288, states[0] = -86.462187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781613171, states[0] = -86.460001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793857416, states[0] = -86.457696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806109741, states[0] = -8.261717, states[40]= 0.002319
Saving checkpoint... 
Iteration: 818285847, states[0] = -86.339855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830457599, states[0] = -86.449060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842703813, states[0] = -86.473233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854848284, states[0] = -86.472848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867042292, states[0] = -86.469281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879167530, states[0] = -86.466763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891305967, states[0] = -86.464247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903482824, states[0] = -86.461575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915730538, states[0] = -86.458770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927907318, states[0] = -86.457291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940077197, states[0] = 8.028779, states[40]= 0.004178
Saving checkpoint... 
Iteration: 952277693, states[0] = -86.329242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964447455, states[0] = -86.446260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976698741, states[0] = -86.473135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988898356, states[0] = -86.472052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001118638, states[0] = -86.467705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013323756, states[0] = -86.463927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025567494, states[0] = -86.460482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037815370, states[0] = -86.457992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050020182, states[0] = 22.104050, states[40]= 0.007835
Saving checkpoint... 
Iteration: 1062226503, states[0] = -86.251278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074323368, states[0] = -86.379960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086610534, states[0] = -86.470133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098815494, states[0] = -86.473187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111030094, states[0] = -86.469484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123229071, states[0] = -86.465556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135482937, states[0] = -86.461530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147739927, states[0] = -86.458638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159865113, states[0] = -86.457567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172039336, states[0] = 18.998280, states[40]= 0.004367
Saving checkpoint... 
Iteration: 1184233967, states[0] = -86.262899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196390790, states[0] = -86.424956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208584877, states[0] = -86.468402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220791308, states[0] = -86.473363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232946628, states[0] = -86.471128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245224473, states[0] = -86.465618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257381458, states[0] = -86.462963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269593819, states[0] = -86.460128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281721741, states[0] = -86.458784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293944162, states[0] = -86.456957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306289435, states[0] = -86.344201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318533761, states[0] = -86.463245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330789590, states[0] = -86.473353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342975112, states[0] = -86.470551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355136768, states[0] = -86.467277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367327059, states[0] = -86.463806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379457250, states[0] = -86.461834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391678455, states[0] = -86.459190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403929948, states[0] = -86.457037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416134195, states[0] = -28.140712, states[40]= 0.000603
Saving checkpoint... 
Iteration: 1428336330, states[0] = -86.390866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440233710, states[0] = -86.262445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452525884, states[0] = -86.462171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464717311, states[0] = -86.473269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476975697, states[0] = -86.470515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489207593, states[0] = -86.465885, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.332512
 - CaMKt in component CaMK (millimolar): 0.000889
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.046246
 - nass in component intracellular_ions (millimolar): 6.046291
 - ki in component intracellular_ions (millimolar): 145.949792
 - kss in component intracellular_ions (millimolar): 145.949782
 - cansr in component intracellular_ions (millimolar): 1.249445
 - cajsr in component intracellular_ions (millimolar): 1.249577
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008578
 - hf in component INa (dimensionless): 0.642075
 - hs in component INa (dimensionless): 0.642075
 - j in component INa (dimensionless): 0.642078
 - hsp in component INa (dimensionless): 0.393090
 - jp in component INa (dimensionless): 0.642080
 - mL in component INaL (dimensionless): 0.000252
 - hL in component INaL (dimensionless): 0.461591
 - hLp in component INaL (dimensionless): 0.272256
 - a in component Ito (dimensionless): 0.001111
 - iF in component Ito (dimensionless): 0.999416
 - iS in component Ito (dimensionless): 0.985428
 - ap in component Ito (dimensionless): 0.000566
 - iFp in component Ito (dimensionless): 0.999416
 - iSp in component Ito (dimensionless): 0.991546
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997445
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001264
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020860
 - xs1 in component IKs (dimensionless): 0.037569
 - xs2 in component IKs (dimensionless): 0.000229
 - xk1 in component IK1 (dimensionless): 0.997141
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:10:43 (67635): called boinc_finish(0)

</stderr_txt>
]]>


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