𝕏

Task 55797919

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_1000-conf_344_0
Workunit 26497097
Created 2 Jul 2024, 14:20:53 UTC
Sent 3 Jul 2024, 1:26:36 UTC
Report deadline 6 Jul 2024, 1:26:36 UTC
Received 3 Jul 2024, 14:55:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236306
Run time 1 hours 16 min 43 sec
CPU time 1 hours 16 min 43 sec
Validate state Valid
Credit 45.17
Device peak FLOPS 3.81 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.89 MB
Peak swap size 6.01 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_1000-conf_344.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_1000-conf_344_0_r155307884_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_1000-conf_344_0_r155307884_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.801130
     * GNaL_b in INaL: 0.005559
     * Gto_b in Ito: 0.086120
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031477
     * GKs_b in IKs: 0.001968
     * GK1_b in IK1: 0.167821
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.131953
     * GKb_b in IKb: 0.003816
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036190
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 14015084, states[0] = 27.147152, states[40]= 0.010067


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_1000-conf_344.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_1000-conf_344_0_r155307884_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Coppini_1000-conf_344_0_r155307884_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.801130
     * GNaL_b in INaL: 0.005559
     * Gto_b in Ito: 0.086120
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031477
     * GKs_b in IKs: 0.001968
     * GK1_b in IK1: 0.167821
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.131953
     * GKb_b in IKb: 0.003816
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036190
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 14015084
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 27.147152 (After loading)
 - states[40]: 0.010067 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 18772440, states[0] = -94.859757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21295255, states[0] = -94.890208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23837215, states[0] = -94.935504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32844541, states[0] = -94.929811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42070361, states[0] = 8.252484, states[40]= 0.004400
Saving checkpoint... 
Iteration: 44925166, states[0] = -94.973405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49221077, states[0] = -94.678802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59815472, states[0] = -94.885575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72314570, states[0] = -94.882287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86566972, states[0] = 10.068370, states[40]= 0.004207
Saving checkpoint... 
Iteration: 96621686, states[0] = -33.823921, states[40]= 0.000720
Saving checkpoint... 
Iteration: 105399941, states[0] = -94.952257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119627528, states[0] = -39.461975, states[40]= 0.000385
Saving checkpoint... 
Iteration: 133560885, states[0] = 12.873288, states[40]= 0.003778
Saving checkpoint... 
Iteration: 138261835, states[0] = -94.786880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147615746, states[0] = -28.043585, states[40]= 0.001081
Saving checkpoint... 
Iteration: 157278214, states[0] = -94.820811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167082831, states[0] = 1.451768, states[40]= 0.004654
Saving checkpoint... 
Iteration: 174544371, states[0] = 19.533377, states[40]= 0.002482
Saving checkpoint... 
Iteration: 183623237, states[0] = -35.218205, states[40]= 0.000628
Saving checkpoint... 
Iteration: 191934275, states[0] = -94.965982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197769606, states[0] = -94.803195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202288645, states[0] = -94.839201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211721633, states[0] = -94.670563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220823780, states[0] = -94.888859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235468814, states[0] = -94.976712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247830304, states[0] = -94.896087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260364926, states[0] = -94.927711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268780612, states[0] = -94.824577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277730878, states[0] = -94.701405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286507886, states[0] = 27.914058, states[40]= 0.099309
Saving checkpoint... 
Iteration: 296687620, states[0] = -94.517787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306454498, states[0] = -94.972322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315998303, states[0] = -94.983093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322533127, states[0] = 23.507298, states[40]= 0.001818
Saving checkpoint... 
Iteration: 337396036, states[0] = -94.947698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343617240, states[0] = -29.448152, states[40]= 0.001009
Saving checkpoint... 
Iteration: 358745303, states[0] = -94.743962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373078424, states[0] = 4.145121, states[40]= 0.004695
Saving checkpoint... 
Iteration: 383057056, states[0] = 14.522828, states[40]= 0.003478
Saving checkpoint... 
Iteration: 388244799, states[0] = -94.742458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400114221, states[0] = -26.561436, states[40]= 0.001139
Saving checkpoint... 
Iteration: 407962632, states[0] = -94.974323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419620078, states[0] = -32.165930, states[40]= 0.000835
Saving checkpoint... 
Iteration: 428504108, states[0] = 33.221403, states[40]= 0.338977
Saving checkpoint... 
Iteration: 437312627, states[0] = -94.874151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448799502, states[0] = -94.855589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456231023, states[0] = -94.701163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461333648, states[0] = -94.898818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471217616, states[0] = -94.655000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484407774, states[0] = -94.953272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497029608, states[0] = 24.604866, states[40]= 0.001697
Saving checkpoint... 
Iteration: 502944039, states[0] = -94.968170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516431989, states[0] = -94.963739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524519526, states[0] = 26.981502, states[40]= 0.003159
Saving checkpoint... 
Iteration: 533618360, states[0] = -30.518985, states[40]= 0.000945
Saving checkpoint... 
Iteration: 543605356, states[0] = -17.963687, states[40]= 0.001415
Saving checkpoint... 
Iteration: 549384531, states[0] = -94.940105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555151549, states[0] = -65.210592, states[40]= 0.000008
Saving checkpoint... 
Iteration: 569654354, states[0] = -68.789977, states[40]= 0.000004
Saving checkpoint... 
Iteration: 576127927, states[0] = -39.795477, states[40]= 0.000370
Saving checkpoint... 
Iteration: 582972229, states[0] = -94.976227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596997160, states[0] = -94.981782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605691398, states[0] = -94.542555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621798403, states[0] = -94.853244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636425814, states[0] = -94.960815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650789174, states[0] = -94.838270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665223062, states[0] = -94.673735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676020586, states[0] = 26.805857, states[40]= 0.002620
Saving checkpoint... 
Iteration: 689927806, states[0] = -94.961419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706766136, states[0] = -94.793692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729307049, states[0] = -94.865466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735001878, states[0] = 45.641190, states[40]= 0.413676
Saving checkpoint... 
Iteration: 744426360, states[0] = -94.960622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749728728, states[0] = -94.692570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758004538, states[0] = 31.908478, states[40]= 0.297535
Saving checkpoint... 
Iteration: 763461536, states[0] = -94.972639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772785919, states[0] = -94.832188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782863477, states[0] = -94.924562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797411008, states[0] = -94.953631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807097888, states[0] = -10.611717, states[40]= 0.002540
Saving checkpoint... 
Iteration: 820123742, states[0] = -35.696477, states[40]= 0.000597
Saving checkpoint... 
Iteration: 831898541, states[0] = -94.947158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840581309, states[0] = 2.419293, states[40]= 0.004690
Saving checkpoint... 
Iteration: 854988547, states[0] = -94.979014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864077716, states[0] = 4.553279, states[40]= 0.004686
Saving checkpoint... 
Iteration: 873905936, states[0] = -94.950852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879746695, states[0] = -94.745720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889257081, states[0] = -94.772213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898584469, states[0] = 0.384066, states[40]= 0.004587
Saving checkpoint... 
Iteration: 905722350, states[0] = -94.670305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912103459, states[0] = -16.083631, states[40]= 0.001600
Saving checkpoint... 
Iteration: 928705313, states[0] = -94.605228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943059880, states[0] = 13.322210, states[40]= 0.003703
Saving checkpoint... 
Iteration: 958019644, states[0] = 26.963552, states[40]= 0.003088
Saving checkpoint... 
Iteration: 973797934, states[0] = -94.851158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979415468, states[0] = -94.955008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988478310, states[0] = -94.976169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997666381, states[0] = -87.626148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004692990, states[0] = -94.549649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010104479, states[0] = -17.094457, states[40]= 0.001492
Saving checkpoint... 
Iteration: 1019723212, states[0] = -94.672869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037022910, states[0] = 26.349281, states[40]= 0.001977
Saving checkpoint... 
Iteration: 1043710078, states[0] = -94.624011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052758881, states[0] = -94.775872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064228542, states[0] = -94.690728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070467587, states[0] = -94.973129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079910021, states[0] = -94.952066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085474707, states[0] = -94.974913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098251942, states[0] = -94.758651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103243152, states[0] = -94.735079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111353868, states[0] = -94.915487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127964252, states[0] = -94.971996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137260581, states[0] = -94.779523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145915006, states[0] = -94.954154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154150096, states[0] = -63.454194, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1159295616, states[0] = -94.846825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172803870, states[0] = -94.859233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181866953, states[0] = -94.925657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189382876, states[0] = -94.936590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196602629, states[0] = -15.259260, states[40]= 0.001705
Saving checkpoint... 
Iteration: 1206582338, states[0] = 1.775279, states[40]= 0.004669
Saving checkpoint... 
Iteration: 1213122837, states[0] = -34.819065, states[40]= 0.000654
Saving checkpoint... 
Iteration: 1222973573, states[0] = -94.974098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232447061, states[0] = -94.966370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241115369, states[0] = -27.656177, states[40]= 0.001098
Saving checkpoint... 
Iteration: 1253088813, states[0] = -2.722972, states[40]= 0.004216
Saving checkpoint... 
Iteration: 1258247558, states[0] = -94.746565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264385031, states[0] = -94.937652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276070851, states[0] = 8.227184, states[40]= 0.004443
Saving checkpoint... 
Iteration: 1283599720, states[0] = -12.387189, states[40]= 0.002177
Saving checkpoint... 
Iteration: 1292632054, states[0] = -43.940717, states[40]= 0.000215
Saving checkpoint... 
Iteration: 1301922559, states[0] = -94.956884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319127811, states[0] = -39.677590, states[40]= 0.000375
Saving checkpoint... 
Iteration: 1339270519, states[0] = -94.800560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351448181, states[0] = -94.966279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357666597, states[0] = -87.923968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366494627, states[0] = -94.978308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373698013, states[0] = -94.572189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385731254, states[0] = -94.698268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394689333, states[0] = -94.526539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404656244, states[0] = -71.383471, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1419198343, states[0] = -94.573487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428705270, states[0] = -94.603087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438473230, states[0] = -94.973179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447777188, states[0] = -94.813495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456337609, states[0] = -94.899046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462170376, states[0] = -91.877205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470168267, states[0] = -89.993321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482036006, states[0] = 22.547522, states[40]= 0.001959
Saving checkpoint... 
Iteration: 1487339938, states[0] = -94.901249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495898716, states[0] = -94.944686, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.854723
 - CaMKt in component CaMK (millimolar): 0.012690
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.706401
 - nass in component intracellular_ions (millimolar): 6.706499
 - ki in component intracellular_ions (millimolar): 145.175550
 - kss in component intracellular_ions (millimolar): 145.175529
 - cansr in component intracellular_ions (millimolar): 1.665903
 - cajsr in component intracellular_ions (millimolar): 1.624326
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003636
 - hf in component INa (dimensionless): 0.879181
 - hs in component INa (dimensionless): 0.879173
 - j in component INa (dimensionless): 0.879124
 - hsp in component INa (dimensionless): 0.724268
 - jp in component INa (dimensionless): 0.879091
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.706370
 - hLp in component INaL (dimensionless): 0.444234
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.612689
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.683916
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916791
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999837
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003054
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.363652
 - xs1 in component IKs (dimensionless): 0.266169
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997350
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:52:55 (6132): called boinc_finish(0)

</stderr_txt>
]]>


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