𝕏

Task 55797706

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_575-conf_43_0
Workunit 26496991
Created 2 Jul 2024, 14:20:48 UTC
Sent 3 Jul 2024, 1:26:36 UTC
Report deadline 6 Jul 2024, 1:26:46 UTC
Received 3 Jul 2024, 13:46:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236306
Run time 1 hours 16 min 5 sec
CPU time 1 hours 16 min 5 sec
Validate state Valid
Credit 42.62
Device peak FLOPS 3.81 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 12.43 MB
Peak swap size 5.97 MB
Peak disk usage 0.20 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_575-conf_43.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_575-conf_43_0_r1719241361_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_575-conf_43_0_r1719241361_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.686278
     * GNaL_b in INaL: 0.005935
     * Gto_b in Ito: 0.085385
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032416
     * GKs_b in IKs: 0.001978
     * GK1_b in IK1: 0.163911
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.830712
     * GKb_b in IKb: 0.003769
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031432
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9284077, states[0] = -4.285493, states[40]= 0.001547
Saving checkpoint... 
Iteration: 18221258, states[0] = -33.620652, states[40]= 0.000208
Saving checkpoint... 
Iteration: 32613593, states[0] = -53.744743, states[40]= 0.000022
Saving checkpoint... 
Iteration: 54235528, states[0] = -84.283547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76621390, states[0] = -79.812447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85882276, states[0] = -84.457515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 98750683, states[0] = -70.242740, states[40]= 0.000002
Saving checkpoint... 
Iteration: 112803968, states[0] = -29.646349, states[40]= 0.000159


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_575-conf_43.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_575-conf_43_0_r1719241361_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_575-conf_43_0_r1719241361_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.686278
     * GNaL_b in INaL: 0.005935
     * Gto_b in Ito: 0.085385
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032416
     * GKs_b in IKs: 0.001978
     * GK1_b in IK1: 0.163911
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.830712
     * GKb_b in IKb: 0.003769
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031432
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 112803968
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -29.646349 (After loading)
 - states[40]: 0.000159 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 121023765, states[0] = -84.748338, states[40]= 0.000001
Saving checkpoint... 
Iteration: 123604745, states[0] = -84.730234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 128055647, states[0] = -45.818383, states[40]= 0.000048
Saving checkpoint... 
Iteration: 136362778, states[0] = -10.323958, states[40]= 0.000241
Saving checkpoint... 
Iteration: 145797353, states[0] = 25.276597, states[40]= 0.000012
Saving checkpoint... 
Iteration: 149470554, states[0] = -84.701892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 153030585, states[0] = -2.755884, states[40]= 0.000241
Saving checkpoint... 
Iteration: 163934854, states[0] = 12.028295, states[40]= 0.000047
Saving checkpoint... 
Iteration: 176806515, states[0] = -84.767765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 191419417, states[0] = -84.597659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201894706, states[0] = 5.752323, states[40]= 0.000117
Saving checkpoint... 
Iteration: 210667318, states[0] = -84.521075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 224504877, states[0] = -84.689610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 238104215, states[0] = 15.300412, states[40]= 0.000026
Saving checkpoint... 
Iteration: 242883358, states[0] = -84.603013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 252022223, states[0] = -84.165442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261740659, states[0] = -43.036747, states[40]= 0.000064
Saving checkpoint... 
Iteration: 271572178, states[0] = -84.164365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279262771, states[0] = -25.411501, states[40]= 0.000163
Saving checkpoint... 
Iteration: 288366804, states[0] = 30.823852, states[40]= 0.486163
Saving checkpoint... 
Iteration: 296728152, states[0] = 28.179886, states[40]= 0.000100
Saving checkpoint... 
Iteration: 302586897, states[0] = -68.662850, states[40]= 0.000003
Saving checkpoint... 
Iteration: 307221554, states[0] = -84.156237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316843181, states[0] = 31.193912, states[40]= 0.003425
Saving checkpoint... 
Iteration: 325862834, states[0] = -54.140291, states[40]= 0.000018
Saving checkpoint... 
Iteration: 340432768, states[0] = 26.221453, states[40]= 0.000021
Saving checkpoint... 
Iteration: 352713972, states[0] = -84.624817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 365348560, states[0] = -84.551053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 373747810, states[0] = -84.771264, states[40]= 0.000001
Saving checkpoint... 
Iteration: 382652308, states[0] = -84.751702, states[40]= 0.000001
Saving checkpoint... 
Iteration: 391512745, states[0] = -84.559091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401490163, states[0] = -73.074858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411018641, states[0] = -84.249516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420633476, states[0] = 30.604534, states[40]= 0.001263
Saving checkpoint... 
Iteration: 427018035, states[0] = -2.715014, states[40]= 0.000240
Saving checkpoint... 
Iteration: 441768790, states[0] = -84.118042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448192621, states[0] = -84.723506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 463202151, states[0] = 22.984918, states[40]= 0.000006
Saving checkpoint... 
Iteration: 477382239, states[0] = -62.517965, states[40]= 0.000006
Saving checkpoint... 
Iteration: 487636780, states[0] = 24.372504, states[40]= 0.000008
Saving checkpoint... 
Iteration: 492640422, states[0] = -83.126356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504255734, states[0] = -84.723663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 512006843, states[0] = -84.688052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 518571280, states[0] = -84.460155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 527426970, states[0] = -82.887479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536192022, states[0] = 30.546249, states[40]= 0.450614
Saving checkpoint... 
Iteration: 547659662, states[0] = -84.696297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 555106475, states[0] = -84.585174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 560908657, states[0] = -84.762076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 572941580, states[0] = -84.629408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 585317075, states[0] = -84.678216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 600406776, states[0] = -32.936229, states[40]= 0.000140
Saving checkpoint... 
Iteration: 605944154, states[0] = -84.248432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619234657, states[0] = -84.650243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627460967, states[0] = -67.381413, states[40]= 0.000003
Saving checkpoint... 
Iteration: 636605004, states[0] = -2.224811, states[40]= 0.000235
Saving checkpoint... 
Iteration: 646600930, states[0] = 31.408259, states[40]= 0.018807
Saving checkpoint... 
Iteration: 652644198, states[0] = 31.014457, states[40]= 0.002381
Saving checkpoint... 
Iteration: 658408746, states[0] = 25.784741, states[40]= 0.000016
Saving checkpoint... 
Iteration: 672619939, states[0] = -83.745784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679027799, states[0] = -84.621002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 685707301, states[0] = 30.888337, states[40]= 0.001920
Saving checkpoint... 
Iteration: 699340680, states[0] = -73.729951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 708119914, states[0] = 29.897912, states[40]= 0.162742
Saving checkpoint... 
Iteration: 724133288, states[0] = -84.450961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738704341, states[0] = -44.356390, states[40]= 0.000056
Saving checkpoint... 
Iteration: 753096225, states[0] = -64.407988, states[40]= 0.000005
Saving checkpoint... 
Iteration: 767716972, states[0] = -15.389221, states[40]= 0.000193
Saving checkpoint... 
Iteration: 778610024, states[0] = 11.930879, states[40]= 0.000047
Saving checkpoint... 
Iteration: 792280101, states[0] = -84.505829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 809121733, states[0] = -21.184181, states[40]= 0.000163
Saving checkpoint... 
Iteration: 832149011, states[0] = -52.568911, states[40]= 0.000022
Saving checkpoint... 
Iteration: 837791398, states[0] = 31.415304, states[40]= 0.006482
Saving checkpoint... 
Iteration: 846987196, states[0] = 31.249234, states[40]= 0.029302
Saving checkpoint... 
Iteration: 852407889, states[0] = -84.681727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 860647779, states[0] = -83.907025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866036023, states[0] = -8.313261, states[40]= 0.000253
Saving checkpoint... 
Iteration: 875528287, states[0] = -13.936458, states[40]= 0.000207
Saving checkpoint... 
Iteration: 885530787, states[0] = 27.094829, states[40]= 0.000040
Saving checkpoint... 
Iteration: 898541970, states[0] = -30.273689, states[40]= 0.000155
Saving checkpoint... 
Iteration: 908155473, states[0] = -84.570145, states[40]= 0.000001
Saving checkpoint... 
Iteration: 921259464, states[0] = -35.987893, states[40]= 0.000117
Saving checkpoint... 
Iteration: 933029185, states[0] = -15.031074, states[40]= 0.000197
Saving checkpoint... 
Iteration: 941696858, states[0] = -65.220384, states[40]= 0.000004
Saving checkpoint... 
Iteration: 956085999, states[0] = -81.436680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965135126, states[0] = -84.753889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 974917202, states[0] = 30.352806, states[40]= 0.423105
Saving checkpoint... 
Iteration: 981525009, states[0] = -83.642078, states[40]= 0.000001
Saving checkpoint... 
Iteration: 991425253, states[0] = -54.008518, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1000859477, states[0] = 4.176810, states[40]= 0.000140
Saving checkpoint... 
Iteration: 1007951709, states[0] = -84.697284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1014518953, states[0] = -84.507034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1031102859, states[0] = -57.089209, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1045721200, states[0] = -5.795721, states[40]= 0.000258
Saving checkpoint... 
Iteration: 1060604392, states[0] = 31.372368, states[40]= 0.005430
Saving checkpoint... 
Iteration: 1076465256, states[0] = 8.703398, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1082328752, states[0] = -84.207332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091483698, states[0] = -64.347552, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1100754048, states[0] = -84.411614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107531466, states[0] = -3.568892, states[40]= 0.000247
Saving checkpoint... 
Iteration: 1112642859, states[0] = 31.251701, states[40]= 0.003841
Saving checkpoint... 
Iteration: 1122266586, states[0] = -83.327421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139859943, states[0] = -84.449437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146780569, states[0] = -84.563682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155970822, states[0] = -84.513305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1167306344, states[0] = 14.097421, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1173586723, states[0] = 31.163745, states[40]= 0.034726
Saving checkpoint... 
Iteration: 1183198268, states[0] = -67.069239, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1188809426, states[0] = -84.745862, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1201666870, states[0] = -84.410865, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1206640974, states[0] = 32.337570, states[40]= 0.647244
Saving checkpoint... 
Iteration: 1214711283, states[0] = 29.788505, states[40]= 0.000465
Saving checkpoint... 
Iteration: 1231377234, states[0] = 31.478627, states[40]= 0.011769
Saving checkpoint... 
Iteration: 1240635685, states[0] = 3.306230, states[40]= 0.000154
Saving checkpoint... 
Iteration: 1249243575, states[0] = 14.253334, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1257493855, states[0] = -84.664924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1262431531, states[0] = 31.053769, states[40]= 0.002526
Saving checkpoint... 
Iteration: 1275814553, states[0] = -84.185187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284763652, states[0] = -84.468207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1292123839, states[0] = -23.678726, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1299401536, states[0] = -84.292096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309328077, states[0] = 15.952224, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1315911253, states[0] = 29.799447, states[40]= 0.000470
Saving checkpoint... 
Iteration: 1325749064, states[0] = -8.907861, states[40]= 0.000250
Saving checkpoint... 
Iteration: 1335520118, states[0] = -4.685598, states[40]= 0.000254
Saving checkpoint... 
Iteration: 1344356544, states[0] = 29.733850, states[40]= 0.221494
Saving checkpoint... 
Iteration: 1356307245, states[0] = -84.103025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361429652, states[0] = -44.680440, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1367538013, states[0] = -84.281537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379315247, states[0] = -84.188877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386963182, states[0] = 10.013927, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1395971392, states[0] = -83.819421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405087671, states[0] = 1.815619, states[40]= 0.000178
Saving checkpoint... 
Iteration: 1422035073, states[0] = 11.910318, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1441505095, states[0] = -84.694867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1453466916, states[0] = -83.368351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459716020, states[0] = -0.899428, states[40]= 0.000219
Saving checkpoint... 
Iteration: 1468437274, states[0] = -84.156546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475554905, states[0] = -30.750860, states[40]= 0.000153
Saving checkpoint... 
Iteration: 1487564971, states[0] = 22.839286, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1496563022, states[0] = -54.295522, states[40]= 0.000018
Total time: 3000350.000000
State Variables:
 - v in component membrane (millivolt): -84.619703
 - CaMKt in component CaMK (millimolar): 0.056662
 - cass in component intracellular_ions (millimolar): 0.000112
 - nai in component intracellular_ions (millimolar): 6.944584
 - nass in component intracellular_ions (millimolar): 6.944761
 - ki in component intracellular_ions (millimolar): 144.634165
 - kss in component intracellular_ions (millimolar): 144.634135
 - cansr in component intracellular_ions (millimolar): 2.242612
 - cajsr in component intracellular_ions (millimolar): 1.857272
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.010187
 - hf in component INa (dimensionless): 0.575165
 - hs in component INa (dimensionless): 0.574925
 - j in component INa (dimensionless): 0.573570
 - hsp in component INa (dimensionless): 0.327613
 - jp in component INa (dimensionless): 0.572084
 - mL in component INaL (dimensionless): 0.000350
 - hL in component INaL (dimensionless): 0.322430
 - hLp in component INaL (dimensionless): 0.137582
 - a in component Ito (dimensionless): 0.001247
 - iF in component Ito (dimensionless): 0.999210
 - iS in component Ito (dimensionless): 0.307012
 - ap in component Ito (dimensionless): 0.000635
 - iFp in component Ito (dimensionless): 0.999211
 - iSp in component Ito (dimensionless): 0.338090
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.814635
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990603
 - jca in component ICaL (dimensionless): 0.994435
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007821
 - xrf in component IKr (dimensionless): 0.001894
 - xrs in component IKr (dimensionless): 0.725138
 - xs1 in component IKs (dimensionless): 0.423759
 - xs2 in component IKs (dimensionless): 0.000287
 - xk1 in component IK1 (dimensionless): 0.996773
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
09:40:37 (30784): called boinc_finish(0)

</stderr_txt>
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