𝕏

Task 55794749

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_333-conf_239_1
Workunit 26495513
Created 2 Jul 2024, 14:19:18 UTC
Sent 3 Jul 2024, 1:01:46 UTC
Report deadline 6 Jul 2024, 1:01:46 UTC
Received 3 Jul 2024, 4:15:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227516
Run time 1 hours 35 min 26 sec
CPU time 1 hours 35 min 26 sec
Validate state Valid
Credit 44.00
Device peak FLOPS 3.77 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.03 MB
Peak swap size 6.22 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_333-conf_239.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_333-conf_239_1_r444168887_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_333-conf_239_1_r444168887_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.208319
     * GNaL_b in INaL: 0.006008
     * Gto_b in Ito: 0.084037
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031867
     * GKs_b in IKs: 0.001892
     * GK1_b in IK1: 0.161294
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.007002
     * GKb_b in IKb: 0.003790
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036817
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7323179, states[0] = -87.838171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17579163, states[0] = -44.359068, states[40]= 0.000078
Saving checkpoint... 
Iteration: 28121194, states[0] = -87.665700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38543126, states[0] = 0.566644, states[40]= 0.006093
Saving checkpoint... 
Iteration: 49045546, states[0] = -2.957174, states[40]= 0.005291
Saving checkpoint... 
Iteration: 59615480, states[0] = -87.629315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70073837, states[0] = -44.404482, states[40]= 0.000086
Saving checkpoint... 
Iteration: 80730399, states[0] = -31.956233, states[40]= 0.000421
Saving checkpoint... 
Iteration: 91092322, states[0] = -76.277527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 101449023, states[0] = -87.690470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111848367, states[0] = 15.355237, states[40]= 0.008833
Saving checkpoint... 
Iteration: 122135244, states[0] = -87.788629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132725906, states[0] = -32.992175, states[40]= 0.000377
Saving checkpoint... 
Iteration: 143322431, states[0] = 32.384931, states[40]= 0.117464
Saving checkpoint... 
Iteration: 153790327, states[0] = -87.758443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164309936, states[0] = -87.827321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174689177, states[0] = 6.335479, states[40]= 0.007073
Saving checkpoint... 
Iteration: 185086889, states[0] = -82.300310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195471965, states[0] = -87.822905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205940963, states[0] = -87.708477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216489010, states[0] = 22.389420, states[40]= 0.041101
Saving checkpoint... 
Iteration: 226731090, states[0] = -53.386192, states[40]= 0.000023
Saving checkpoint... 
Iteration: 237319324, states[0] = 22.831928, states[40]= 0.049699
Saving checkpoint... 
Iteration: 247833092, states[0] = 16.264972, states[40]= 0.009272
Saving checkpoint... 
Iteration: 258220886, states[0] = -43.405743, states[40]= 0.000099
Saving checkpoint... 
Iteration: 268626002, states[0] = -87.806697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278995199, states[0] = 17.020098, states[40]= 0.009774
Saving checkpoint... 
Iteration: 289467578, states[0] = -87.837060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299985138, states[0] = 20.603608, states[40]= 0.018900
Saving checkpoint... 
Iteration: 310775713, states[0] = -87.762596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321344342, states[0] = 3.817886, states[40]= 0.006705
Saving checkpoint... 
Iteration: 331703392, states[0] = -29.383227, states[40]= 0.000547
Saving checkpoint... 
Iteration: 342141209, states[0] = 23.367928, states[40]= 0.060603
Saving checkpoint... 
Iteration: 352581411, states[0] = -87.450093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363006769, states[0] = 3.879208, states[40]= 0.006714
Saving checkpoint... 
Iteration: 373507270, states[0] = 2.563138, states[40]= 0.006499
Saving checkpoint... 
Iteration: 384092855, states[0] = -87.724925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394758395, states[0] = -87.724609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405150184, states[0] = 16.534305, states[40]= 0.009434
Saving checkpoint... 
Iteration: 415464443, states[0] = 25.965460, states[40]= 0.101909
Saving checkpoint... 
Iteration: 425934016, states[0] = -87.774073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436317784, states[0] = 14.281536, states[40]= 0.008459
Saving checkpoint... 
Iteration: 446734425, states[0] = -86.866117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457176977, states[0] = -9.892607, states[40]= 0.003302
Saving checkpoint... 
Iteration: 467496396, states[0] = 3.815938, states[40]= 0.006704
Saving checkpoint... 
Iteration: 474726156, states[0] = -83.976356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485014739, states[0] = -20.008119, states[40]= 0.001260
Saving checkpoint... 
Iteration: 495330444, states[0] = 0.741926, states[40]= 0.006162
Saving checkpoint... 
Iteration: 505540655, states[0] = -59.455557, states[40]= 0.000009
Saving checkpoint... 
Iteration: 515904622, states[0] = -87.659291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526387183, states[0] = -83.513583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536852851, states[0] = -33.969307, states[40]= 0.000337
Saving checkpoint... 
Iteration: 547381865, states[0] = -79.355953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557759131, states[0] = -87.791357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568035077, states[0] = -60.482867, states[40]= 0.000007
Saving checkpoint... 
Iteration: 578450187, states[0] = 23.852794, states[40]= 0.070183
Saving checkpoint... 
Iteration: 589040564, states[0] = -72.964833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 599505021, states[0] = -22.469765, states[40]= 0.001011
Saving checkpoint... 
Iteration: 609866368, states[0] = -63.815596, states[40]= 0.000004
Saving checkpoint... 
Iteration: 620282709, states[0] = 22.068224, states[40]= 0.035462
Saving checkpoint... 
Iteration: 630837919, states[0] = -26.274289, states[40]= 0.000728
Saving checkpoint... 
Iteration: 641276025, states[0] = 24.928808, states[40]= 0.088608
Saving checkpoint... 
Iteration: 652113350, states[0] = 21.867924, states[40]= 0.032288
Saving checkpoint... 
Iteration: 663452319, states[0] = 19.133157, states[40]= 0.012757
Saving checkpoint... 
Iteration: 674618816, states[0] = 18.707492, states[40]= 0.011843
Saving checkpoint... 
Iteration: 681893895, states[0] = -87.711177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692258741, states[0] = -87.831311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702599631, states[0] = 33.212425, states[40]= 0.114718
Saving checkpoint... 
Iteration: 713024760, states[0] = -67.140480, states[40]= 0.000003
Saving checkpoint... 
Iteration: 723559135, states[0] = -87.725625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734126220, states[0] = 11.265347, states[40]= 0.007791
Saving checkpoint... 
Iteration: 744498490, states[0] = -33.606706, states[40]= 0.000351
Saving checkpoint... 
Iteration: 754842082, states[0] = -49.295982, states[40]= 0.000042
Saving checkpoint... 
Iteration: 765167470, states[0] = -39.644116, states[40]= 0.000166
Saving checkpoint... 
Iteration: 775519298, states[0] = -68.459313, states[40]= 0.000002
Saving checkpoint... 
Iteration: 785839973, states[0] = -50.705375, states[40]= 0.000034
Saving checkpoint... 
Iteration: 796182157, states[0] = -65.570541, states[40]= 0.000003
Saving checkpoint... 
Iteration: 806569801, states[0] = -87.798282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817160126, states[0] = -36.689315, states[40]= 0.000243
Saving checkpoint... 
Iteration: 827763749, states[0] = 21.358143, states[40]= 0.025561
Saving checkpoint... 
Iteration: 838107675, states[0] = 16.113509, states[40]= 0.009188
Saving checkpoint... 
Iteration: 848430892, states[0] = 20.364102, states[40]= 0.017422
Saving checkpoint... 
Iteration: 858650185, states[0] = -28.672516, states[40]= 0.000586
Saving checkpoint... 
Iteration: 865758585, states[0] = 21.894541, states[40]= 0.032686
Saving checkpoint... 
Iteration: 876015753, states[0] = -79.490518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886503600, states[0] = -61.049319, states[40]= 0.000007
Saving checkpoint... 
Iteration: 896893149, states[0] = -87.795040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907415078, states[0] = 26.211208, states[40]= 0.104450
Saving checkpoint... 
Iteration: 917983639, states[0] = -37.051357, states[40]= 0.000232
Saving checkpoint... 
Iteration: 928297416, states[0] = -11.093899, states[40]= 0.002969
Saving checkpoint... 
Iteration: 938566154, states[0] = -87.827297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948739983, states[0] = 41.371428, states[40]= 0.056603
Saving checkpoint... 
Iteration: 959015004, states[0] = -86.413200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969376162, states[0] = -87.760341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979666512, states[0] = -70.100571, states[40]= 0.000002
Saving checkpoint... 
Iteration: 990127016, states[0] = -14.503033, states[40]= 0.002146
Saving checkpoint... 
Iteration: 1000493415, states[0] = -62.940377, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1007658476, states[0] = -61.552301, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1018030503, states[0] = -87.729137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028232816, states[0] = 37.690286, states[40]= 0.091103
Saving checkpoint... 
Iteration: 1038445932, states[0] = -2.372346, states[40]= 0.005458
Saving checkpoint... 
Iteration: 1048735037, states[0] = 25.194595, states[40]= 0.092438
Saving checkpoint... 
Iteration: 1059027815, states[0] = -87.735565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069271109, states[0] = 2.487468, states[40]= 0.006486
Saving checkpoint... 
Iteration: 1079507588, states[0] = -87.356185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089730475, states[0] = 25.778812, states[40]= 0.099839
Saving checkpoint... 
Iteration: 1099962910, states[0] = -33.569296, states[40]= 0.000353
Saving checkpoint... 
Iteration: 1110249213, states[0] = 14.956383, states[40]= 0.008681
Saving checkpoint... 
Iteration: 1120543897, states[0] = -87.815298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130705751, states[0] = -87.803494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140804097, states[0] = -50.173399, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1150973047, states[0] = -54.922516, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1161259332, states[0] = 4.647123, states[40]= 0.006831
Saving checkpoint... 
Iteration: 1171515598, states[0] = -87.731108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181774298, states[0] = -14.198190, states[40]= 0.002211
Saving checkpoint... 
Iteration: 1192041624, states[0] = -87.829400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202596594, states[0] = -2.813770, states[40]= 0.005344
Saving checkpoint... 
Iteration: 1213120385, states[0] = -36.497602, states[40]= 0.000249
Saving checkpoint... 
Iteration: 1223556247, states[0] = 21.849128, states[40]= 0.032003
Saving checkpoint... 
Iteration: 1233870159, states[0] = -87.827592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244196150, states[0] = -87.808808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254487567, states[0] = -86.995175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264899333, states[0] = 15.562957, states[40]= 0.008922
Saving checkpoint... 
Iteration: 1275289649, states[0] = -48.755225, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1285681507, states[0] = -87.773586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296055447, states[0] = 19.253023, states[40]= 0.013061
Saving checkpoint... 
Iteration: 1304379237, states[0] = 22.850394, states[40]= 0.050076
Saving checkpoint... 
Iteration: 1314771416, states[0] = -28.927292, states[40]= 0.000572
Saving checkpoint... 
Iteration: 1325227375, states[0] = 15.148526, states[40]= 0.008752
Saving checkpoint... 
Iteration: 1335563351, states[0] = 12.982389, states[40]= 0.008125
Saving checkpoint... 
Iteration: 1345957907, states[0] = -61.448476, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1356476451, states[0] = -86.784266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367051244, states[0] = 17.918485, states[40]= 0.010649
Saving checkpoint... 
Iteration: 1377513968, states[0] = -87.801718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387877079, states[0] = 20.309032, states[40]= 0.017117
Saving checkpoint... 
Iteration: 1398111508, states[0] = -49.900322, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1408460436, states[0] = -76.119947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1418929421, states[0] = -31.365113, states[40]= 0.000449
Saving checkpoint... 
Iteration: 1429387640, states[0] = 12.774504, states[40]= 0.008079
Saving checkpoint... 
Iteration: 1439759519, states[0] = -29.764342, states[40]= 0.000527
Saving checkpoint... 
Iteration: 1449946608, states[0] = -60.064942, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1460380910, states[0] = 14.931080, states[40]= 0.008671
Saving checkpoint... 
Iteration: 1470654905, states[0] = -87.741854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480971558, states[0] = -87.590467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491360557, states[0] = 22.840572, states[40]= 0.049871
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.720356
 - CaMKt in component CaMK (millimolar): 0.041290
 - cass in component intracellular_ions (millimolar): 0.000115
 - nai in component intracellular_ions (millimolar): 6.976637
 - nass in component intracellular_ions (millimolar): 6.976785
 - ki in component intracellular_ions (millimolar): 144.946866
 - kss in component intracellular_ions (millimolar): 144.946833
 - cansr in component intracellular_ions (millimolar): 1.606422
 - cajsr in component intracellular_ions (millimolar): 1.180041
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.007461
 - hf in component INa (dimensionless): 0.692634
 - hs in component INa (dimensionless): 0.692397
 - j in component INa (dimensionless): 0.681739
 - hsp in component INa (dimensionless): 0.447540
 - jp in component INa (dimensionless): 0.655034
 - mL in component INaL (dimensionless): 0.000194
 - hL in component INaL (dimensionless): 0.292782
 - hLp in component INaL (dimensionless): 0.136040
 - a in component Ito (dimensionless): 0.001012
 - iF in component Ito (dimensionless): 0.999541
 - iS in component Ito (dimensionless): 0.175529
 - ap in component Ito (dimensionless): 0.000516
 - iFp in component Ito (dimensionless): 0.999541
 - iSp in component Ito (dimensionless): 0.212305
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.803441
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966606
 - jca in component ICaL (dimensionless): 0.947870
 - ffp in component ICaL (dimensionless): 0.999862
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009337
 - xrf in component IKr (dimensionless): 0.028951
 - xrs in component IKr (dimensionless): 0.789359
 - xs1 in component IKs (dimensionless): 0.459335
 - xs2 in component IKs (dimensionless): 0.001194
 - xk1 in component IK1 (dimensionless): 0.996806
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:09:14 (1928): called boinc_finish(0)

</stderr_txt>
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