𝕏

Task 55784170

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_8000-conf_16_0
Workunit 26490229
Created 2 Jul 2024, 14:14:15 UTC
Sent 2 Jul 2024, 23:39:52 UTC
Report deadline 5 Jul 2024, 23:39:52 UTC
Received 3 Jul 2024, 8:45:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241141
Run time 1 hours 14 min 39 sec
CPU time 1 hours 2 min 34 sec
Validate state Valid
Credit 45.86
Device peak FLOPS 5.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.88 MB
Peak swap size 4.10 GB
Peak disk usage 2.47 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_8000-conf_16.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_8000-conf_16_0_r579668731_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Schmidt_8000-conf_16_0_r579668731_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.334440
     * GNaL_b in INaL: 0.005500
     * Gto_b in Ito: 0.081995
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032371
     * GKs_b in IKs: 0.001907
     * GK1_b in IK1: 0.160566
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.043529
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028716
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 375.000000
     * CL_0 in membrane: 8000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1496000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11809459, states[0] = -84.117769, states[40]= 0.000001
Saving checkpoint... 
Iteration: 23392295, states[0] = -83.984808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 36198515, states[0] = -81.898767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46971170, states[0] = -83.869020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 60346105, states[0] = -83.657315, states[40]= 0.000001
Saving checkpoint... 
Iteration: 73019679, states[0] = -83.863716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 85817543, states[0] = -83.822088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 98563161, states[0] = -83.802569, states[40]= 0.000001
Saving checkpoint... 
Iteration: 110807223, states[0] = -83.794665, states[40]= 0.000001
Saving checkpoint... 
Iteration: 123832700, states[0] = -83.785969, states[40]= 0.000001
Saving checkpoint... 
Iteration: 136149223, states[0] = -33.849573, states[40]= 0.000503
Saving checkpoint... 
Iteration: 148976374, states[0] = -83.829378, states[40]= 0.000001
Saving checkpoint... 
Iteration: 160615580, states[0] = -83.824010, states[40]= 0.000001
Saving checkpoint... 
Iteration: 172881463, states[0] = -83.830675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 186194662, states[0] = -83.786460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198876972, states[0] = -83.779256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 211562747, states[0] = -83.775789, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225293468, states[0] = -83.808587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 237248032, states[0] = -83.810341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 249267709, states[0] = -83.809249, states[40]= 0.000001
Saving checkpoint... 
Iteration: 260445440, states[0] = -83.743900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 273016397, states[0] = -83.821209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285982543, states[0] = -83.787360, states[40]= 0.000001
Saving checkpoint... 
Iteration: 299480664, states[0] = -83.774663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 312204941, states[0] = -81.297497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324220751, states[0] = -83.015497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337223038, states[0] = -83.810675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348116904, states[0] = -6.236141, states[40]= 0.001176
Saving checkpoint... 
Iteration: 361916793, states[0] = -83.788326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 374728237, states[0] = -83.778106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 387090714, states[0] = -83.775919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 399493438, states[0] = -83.774330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 410909992, states[0] = -83.776842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423611589, states[0] = -83.773944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 436234409, states[0] = -83.140523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447736003, states[0] = -83.773584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 460429060, states[0] = -83.727265, states[40]= 0.000001
Saving checkpoint... 
Iteration: 473167755, states[0] = -83.813055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486473976, states[0] = -83.780100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 500303952, states[0] = -83.472460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512310463, states[0] = -83.494678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523581504, states[0] = -83.773880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 536196188, states[0] = -75.601280, states[40]= 0.000001
Saving checkpoint... 
Iteration: 548694789, states[0] = -83.827134, states[40]= 0.000001
Saving checkpoint... 
Iteration: 560778344, states[0] = -83.829006, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571920080, states[0] = -83.772995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 584565315, states[0] = -83.807593, states[40]= 0.000001
Saving checkpoint... 
Iteration: 597150699, states[0] = -83.813712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610157485, states[0] = -83.783781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 622991613, states[0] = -83.776072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 636019593, states[0] = 31.295609, states[40]= 0.001875
Saving checkpoint... 
Iteration: 648281318, states[0] = -83.383357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661261001, states[0] = -83.808420, states[40]= 0.000001
Saving checkpoint... 
Iteration: 673711204, states[0] = -83.792584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 686843770, states[0] = -83.776850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 699819919, states[0] = -83.773029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 712439717, states[0] = -83.737559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 724268501, states[0] = -83.324366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737756138, states[0] = -83.791350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750392633, states[0] = -83.780578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 762650286, states[0] = -83.778131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 775255797, states[0] = -83.774628, states[40]= 0.000001
Saving checkpoint... 
Iteration: 787808189, states[0] = -83.772932, states[40]= 0.000001
Saving checkpoint... 
Iteration: 800819595, states[0] = -83.828137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 812666612, states[0] = -83.824762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 826059620, states[0] = -83.785017, states[40]= 0.000001
Saving checkpoint... 
Iteration: 838100131, states[0] = -83.784339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 850154080, states[0] = -83.783494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864243529, states[0] = -83.192861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876833544, states[0] = -83.827706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 888092674, states[0] = 6.975309, states[40]= 0.000666
Saving checkpoint... 
Iteration: 900907088, states[0] = -83.825139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 912914290, states[0] = -83.824819, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924895574, states[0] = -83.825572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 937627388, states[0] = -83.794533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 949824572, states[0] = -83.789433, states[40]= 0.000001
Saving checkpoint... 
Iteration: 962468401, states[0] = -83.779485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 974781915, states[0] = -83.776855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 987409484, states[0] = -83.773762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 998875966, states[0] = -83.776209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1011527459, states[0] = -83.773351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1023736833, states[0] = -83.772767, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1036295647, states[0] = -83.441231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048262515, states[0] = -83.294270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061489498, states[0] = -83.798758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1072314858, states[0] = -83.508108, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1084009743, states[0] = 30.104760, states[40]= 0.058941
Saving checkpoint... 
Iteration: 1096670372, states[0] = -83.824685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1109707118, states[0] = -83.792080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1122421780, states[0] = -83.779740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1135024946, states[0] = -83.775176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146565997, states[0] = -83.778304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1158428819, states[0] = -83.779616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1171385527, states[0] = -83.773585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1185311139, states[0] = -83.805487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1198011805, states[0] = -83.785319, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1211456975, states[0] = -83.773289, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224314977, states[0] = -83.508267, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1236842205, states[0] = -83.826971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1249912319, states[0] = -83.787134, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260236399, states[0] = -83.151280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272863944, states[0] = -83.826250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1286703629, states[0] = -83.776979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1298504025, states[0] = -83.778663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1311620443, states[0] = -83.772662, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1324624289, states[0] = -83.819086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1336198321, states[0] = -77.483123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1348909060, states[0] = -83.824431, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1360006353, states[0] = 29.050150, states[40]= 0.192865
Saving checkpoint... 
Iteration: 1371404660, states[0] = -83.773238, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1383311656, states[0] = -83.773555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1395511253, states[0] = -83.772860, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408481157, states[0] = -83.769198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1420417151, states[0] = -83.712669, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1432592699, states[0] = -83.813212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1444408007, states[0] = -83.701404, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1456079832, states[0] = 12.355909, states[40]= 0.000353
Saving checkpoint... 
Iteration: 1469746887, states[0] = -83.790553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1481602427, states[0] = -83.794511, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1493467948, states[0] = -83.798911, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -83.647516
 - CaMKt in component CaMK (millimolar): 0.000869
 - cass in component intracellular_ions (millimolar): 0.000092
 - nai in component intracellular_ions (millimolar): 6.075534
 - nass in component intracellular_ions (millimolar): 6.075642
 - ki in component intracellular_ions (millimolar): 145.828210
 - kss in component intracellular_ions (millimolar): 145.828201
 - cansr in component intracellular_ions (millimolar): 1.650084
 - cajsr in component intracellular_ions (millimolar): 1.650064
 - cai in component intracellular_ions (millimolar): 0.000095
 - m in component INa (dimensionless): 0.011229
 - hf in component INa (dimensionless): 0.535740
 - hs in component INa (dimensionless): 0.535740
 - j in component INa (dimensionless): 0.535741
 - hsp in component INa (dimensionless): 0.294106
 - jp in component INa (dimensionless): 0.535741
 - mL in component INaL (dimensionless): 0.000420
 - hL in component INaL (dimensionless): 0.374587
 - hLp in component INaL (dimensionless): 0.207428
 - a in component Ito (dimensionless): 0.001331
 - iF in component Ito (dimensionless): 0.999065
 - iS in component Ito (dimensionless): 0.998865
 - ap in component Ito (dimensionless): 0.000678
 - iFp in component Ito (dimensionless): 0.999065
 - iSp in component Ito (dimensionless): 0.998985
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999939
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003669
 - xrf in component IKr (dimensionless): 0.000015
 - xrs in component IKr (dimensionless): 0.001031
 - xs1 in component IKs (dimensionless): 0.005897
 - xs2 in component IKs (dimensionless): 0.000310
 - xk1 in component IK1 (dimensionless): 0.997000
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
01:12:03 (31967): called boinc_finish(0)

</stderr_txt>
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