𝕏

Task 55780226

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_ENDO_4000-conf_710_1
Workunit 26488257
Created 2 Jul 2024, 14:12:25 UTC
Sent 2 Jul 2024, 23:09:08 UTC
Report deadline 5 Jul 2024, 23:09:08 UTC
Received 4 Jul 2024, 6:31:24 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 2 min 30 sec
CPU time 1 hours 30 min
Validate state Valid
Credit 44.53
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_ENDO_4000-conf_710.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_ENDO_4000-conf_710_1_r1679084364_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Drouin_ENDO_4000-conf_710_1_r1679084364_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.750041
     * GNaL_b in INaL: 0.005715
     * Gto_b in Ito: 0.083858
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031427
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.164756
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.723705
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037493
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7965903, states[0] = -94.136910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16028427, states[0] = 30.053888, states[40]= 0.000490
Saving checkpoint... 
Iteration: 23737488, states[0] = -94.019802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32215780, states[0] = -91.874936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40427648, states[0] = -93.928941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48534088, states[0] = -93.980734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57184081, states[0] = -93.989819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65339434, states[0] = -93.982772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72802467, states[0] = -94.000056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81561371, states[0] = -93.974838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90172462, states[0] = -48.569542, states[40]= 0.000289
Saving checkpoint... 
Iteration: 97507150, states[0] = -93.975498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105319535, states[0] = -93.980794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113848423, states[0] = -93.967606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121824091, states[0] = -93.967916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130781833, states[0] = -93.998197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138972691, states[0] = -93.993064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147312519, states[0] = -93.980417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156876486, states[0] = -93.996182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165110691, states[0] = -93.987530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173894100, states[0] = -93.966201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180817162, states[0] = -93.997426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189177409, states[0] = -93.984887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197905754, states[0] = -93.965895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205992175, states[0] = -93.964465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213544764, states[0] = -93.973358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222022719, states[0] = 31.468999, states[40]= 0.000788
Saving checkpoint... 
Iteration: 232071090, states[0] = 17.094813, states[40]= 0.001150
Saving checkpoint... 
Iteration: 240497252, states[0] = -93.958181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248771957, states[0] = -93.997623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256675030, states[0] = -93.995145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265540700, states[0] = -93.973311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274096846, states[0] = 6.089179, states[40]= 0.003138
Saving checkpoint... 
Iteration: 283333309, states[0] = -93.979210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290723894, states[0] = -93.997037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299088066, states[0] = -93.987959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307427392, states[0] = -93.976284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316147534, states[0] = -29.517741, states[40]= 0.002316
Saving checkpoint... 
Iteration: 324670981, states[0] = -93.994722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333202566, states[0] = -93.983558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341047095, states[0] = -93.989453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351045744, states[0] = -93.989481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359850280, states[0] = -93.966427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368210054, states[0] = -85.189696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376534088, states[0] = -93.971847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384696494, states[0] = -93.995929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393511754, states[0] = -93.973749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401884250, states[0] = -93.965727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410923781, states[0] = -93.993913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418555862, states[0] = -93.977927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426947145, states[0] = -93.993052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435326026, states[0] = -93.979079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442790639, states[0] = -93.997059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450565566, states[0] = -93.980195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459494104, states[0] = -93.974062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467528350, states[0] = -93.973142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476025821, states[0] = 31.057846, states[40]= 0.000336
Saving checkpoint... 
Iteration: 485028913, states[0] = -93.989820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493202047, states[0] = -93.983198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500566618, states[0] = -93.980318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508415537, states[0] = -93.901582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516353010, states[0] = -93.816798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525807908, states[0] = -93.966815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533671609, states[0] = -93.969571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542659291, states[0] = -93.993384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550277078, states[0] = -93.610515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558914518, states[0] = -93.993877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567265130, states[0] = -93.980795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574774808, states[0] = -93.996835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583197160, states[0] = -93.983163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591745763, states[0] = -93.967872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599232805, states[0] = -93.981845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607122556, states[0] = -93.985898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615659313, states[0] = -93.969649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623511353, states[0] = -93.973216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631349899, states[0] = -93.977855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638926388, states[0] = -93.993285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647782851, states[0] = -93.967005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656117469, states[0] = -6.169405, states[40]= 0.003226
Saving checkpoint... 
Iteration: 664801999, states[0] = -93.996417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673083462, states[0] = -93.987250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681340670, states[0] = -93.978028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689480272, states[0] = -93.973892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698629191, states[0] = -93.990186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707388906, states[0] = -93.976472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714965230, states[0] = -93.991709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724225221, states[0] = -93.146076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731155098, states[0] = -93.984370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739346848, states[0] = -93.977695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746777540, states[0] = -93.996421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755022955, states[0] = -93.989413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763718495, states[0] = -93.968024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771995199, states[0] = -93.963035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779866698, states[0] = -93.965139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787175111, states[0] = -93.983491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794842067, states[0] = -93.995401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803146752, states[0] = -93.984514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811460820, states[0] = -93.974140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818988381, states[0] = -93.990593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827177884, states[0] = -93.983294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834861726, states[0] = -93.994824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843355502, states[0] = -93.977177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851985320, states[0] = -93.962999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860316325, states[0] = -93.735559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869152702, states[0] = -93.984134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877881502, states[0] = -93.964648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886219110, states[0] = -92.184820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894454576, states[0] = -93.932796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902966188, states[0] = -93.991230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910501324, states[0] = -93.958386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918274377, states[0] = -93.599109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926757798, states[0] = -93.995988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935099207, states[0] = -93.986021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942364728, states[0] = -93.835852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950596998, states[0] = -93.985162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958416513, states[0] = -93.901472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966980194, states[0] = -93.990554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975265966, states[0] = -93.979802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985373548, states[0] = -93.976282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993700425, states[0] = -93.967860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001732028, states[0] = -93.967181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009929600, states[0] = -93.963519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017872701, states[0] = -93.964470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025864592, states[0] = -93.964594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035598435, states[0] = -93.970058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043769387, states[0] = -93.966331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052239070, states[0] = -93.435869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060981425, states[0] = -93.990285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069553298, states[0] = -93.971082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077191485, states[0] = -93.982202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085268850, states[0] = -93.979443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093442959, states[0] = -93.973976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101963554, states[0] = -93.962750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110168149, states[0] = -45.104319, states[40]= 0.000468
Saving checkpoint... 
Iteration: 1118762556, states[0] = -93.995552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126342892, states[0] = -93.796030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134900165, states[0] = -93.992987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144117099, states[0] = -5.895449, states[40]= 0.003270
Saving checkpoint... 
Iteration: 1153463952, states[0] = -93.973244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161655682, states[0] = -93.968438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170035898, states[0] = 28.906725, states[40]= 0.000173
Saving checkpoint... 
Iteration: 1178527912, states[0] = -93.967941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186543940, states[0] = -93.972897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195382567, states[0] = -93.975510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203366492, states[0] = -93.975984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211291495, states[0] = -93.978379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219872345, states[0] = -93.963998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227879163, states[0] = -93.963860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235690785, states[0] = -93.967493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244075699, states[0] = 15.296188, states[40]= 0.001434
Saving checkpoint... 
Iteration: 1252302887, states[0] = -93.696899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260430453, states[0] = -93.913504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268984532, states[0] = -93.989676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276955337, states[0] = -93.990747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285059307, states[0] = -93.986745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293987758, states[0] = -93.961915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301997113, states[0] = -93.961751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309962366, states[0] = -93.962277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318145904, states[0] = -28.314372, states[40]= 0.002412
Saving checkpoint... 
Iteration: 1326388698, states[0] = -93.869442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334796154, states[0] = -93.994902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342941597, states[0] = -93.991088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351639527, states[0] = -93.968353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359194674, states[0] = -93.981419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367854778, states[0] = -93.963960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375720053, states[0] = -93.966543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384187013, states[0] = -60.112989, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1392049076, states[0] = 24.975571, states[40]= 0.000350
Saving checkpoint... 
Iteration: 1400766462, states[0] = -93.994893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409375428, states[0] = -93.975222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417921001, states[0] = -93.962696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426606718, states[0] = -93.985552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434562553, states[0] = -93.977169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443083263, states[0] = -93.985439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452149429, states[0] = -30.913097, states[40]= 0.002154
Saving checkpoint... 
Iteration: 1460764166, states[0] = -93.994748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469154120, states[0] = -93.982663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477539507, states[0] = -93.970466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485427621, states[0] = -93.973488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493927920, states[0] = -93.962401, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.837207
 - CaMKt in component CaMK (millimolar): 0.002067
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.718291
 - nass in component intracellular_ions (millimolar): 6.718413
 - ki in component intracellular_ions (millimolar): 145.141756
 - kss in component intracellular_ions (millimolar): 145.141745
 - cansr in component intracellular_ions (millimolar): 1.826434
 - cajsr in component intracellular_ions (millimolar): 1.826277
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.004029
 - hf in component INa (dimensionless): 0.860265
 - hs in component INa (dimensionless): 0.860265
 - j in component INa (dimensionless): 0.860269
 - hsp in component INa (dimensionless): 0.689712
 - jp in component INa (dimensionless): 0.860271
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.700235
 - hLp in component INaL (dimensionless): 0.504577
 - a in component Ito (dimensionless): 0.000670
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.991400
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.996551
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996433
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005198
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008110
 - xs1 in component IKs (dimensionless): 0.041585
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997603
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:19:43 (66796): called boinc_finish(0)

</stderr_txt>
]]>


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