𝕏

Task 55778948

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_307_0
Workunit 26487619
Created 2 Jul 2024, 14:11:53 UTC
Sent 2 Jul 2024, 23:06:13 UTC
Report deadline 6 Jul 2024, 8:42:13 UTC
Received 3 Jul 2024, 19:01:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234122
Run time 1 hours 48 min 3 sec
CPU time 1 hours 39 min 55 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 4.92 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.16 MB
Peak swap size 5.25 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_307.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_307_0_r1938951631_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pueyo_APDR-conf_307_0_r1938951631_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.440577
     * GNaL_b in INaL: 0.005864
     * Gto_b in Ito: 0.082128
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032157
     * GKs_b in IKs: 0.001887
     * GK1_b in IK1: 0.161884
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.445909
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028818
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16570642, states[0] = 0.735789, states[40]= 0.004383
Saving checkpoint... 
Iteration: 37732249, states[0] = -94.881136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58813767, states[0] = -94.950029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79312919, states[0] = -94.940978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101240339, states[0] = -94.862174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123981247, states[0] = -94.991502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147785787, states[0] = -94.910763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171301624, states[0] = -94.923394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194758714, states[0] = -94.881418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215749764, states[0] = -94.870024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237397779, states[0] = -94.971118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261429597, states[0] = -94.979504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285538564, states[0] = 15.875736, states[40]= 0.005373
Saving checkpoint... 
Iteration: 309948904, states[0] = -94.983467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330695104, states[0] = -94.775990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346073615, states[0] = 0.860732, states[40]= 0.004389
Saving checkpoint... 
Iteration: 368407977, states[0] = -94.973929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390392764, states[0] = -94.969353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414197764, states[0] = -94.781528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438217682, states[0] = -94.820138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461425087, states[0] = -94.978279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478239271, states[0] = -94.855145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500893689, states[0] = -94.969577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518219420, states[0] = -94.823174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542751159, states[0] = -94.871453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560614702, states[0] = -34.088093, states[40]= 0.000294
Saving checkpoint... 
Iteration: 581858213, states[0] = -94.956092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601559588, states[0] = 7.605520, states[40]= 0.004883
Saving checkpoint... 
Iteration: 613830182, states[0] = -94.941725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635958242, states[0] = -94.984950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651367257, states[0] = -94.959911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674530785, states[0] = 18.504970, states[40]= 0.006033
Saving checkpoint... 
Iteration: 699666453, states[0] = -93.868931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722715918, states[0] = -94.816771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736333864, states[0] = -94.943760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759414888, states[0] = -94.975543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783138411, states[0] = -58.901945, states[40]= 0.000006
Saving checkpoint... 
Iteration: 803983603, states[0] = -94.988778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827234481, states[0] = -94.847761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848039693, states[0] = 15.468137, states[40]= 0.005316
Saving checkpoint... 
Iteration: 861982465, states[0] = -94.988584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868007902, states[0] = 24.513985, states[40]= 0.085917
Saving checkpoint... 
Iteration: 874552295, states[0] = 10.632804, states[40]= 0.004988
Saving checkpoint... 
Iteration: 882257362, states[0] = -94.879013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895783285, states[0] = -94.906669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903072394, states[0] = 1.523766, states[40]= 0.004464
Saving checkpoint... 
Iteration: 910232785, states[0] = -94.845091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919419584, states[0] = -94.976643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929687746, states[0] = -94.758971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939584535, states[0] = -6.225725, states[40]= 0.003159
Saving checkpoint... 
Iteration: 941263909, states[0] = -94.886668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945055479, states[0] = 9.336910, states[40]= 0.004945
Saving checkpoint... 
Iteration: 949522072, states[0] = 20.904319, states[40]= 0.008346
Saving checkpoint... 
Iteration: 952346825, states[0] = -94.950489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955831369, states[0] = -94.942195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960274301, states[0] = -94.897857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966041798, states[0] = 14.693586, states[40]= 0.005227
Saving checkpoint... 
Iteration: 982341026, states[0] = -94.947503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004129564, states[0] = -49.154417, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1025646438, states[0] = -68.724190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1047020856, states[0] = 21.180233, states[40]= 0.009095
Saving checkpoint... 
Iteration: 1067291561, states[0] = -94.913959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088452783, states[0] = -94.983683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106170356, states[0] = -94.465285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128956749, states[0] = -94.984372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150619869, states[0] = -39.134736, states[40]= 0.000148
Saving checkpoint... 
Iteration: 1171391832, states[0] = -94.968550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192383396, states[0] = -94.965687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213078812, states[0] = -2.215109, states[40]= 0.003945
Saving checkpoint... 
Iteration: 1233799962, states[0] = -94.920759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254263369, states[0] = -94.885852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269473535, states[0] = -94.987030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291275489, states[0] = -94.898850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306757999, states[0] = -94.879511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328012559, states[0] = 22.770023, states[40]= 0.029687
Saving checkpoint... 
Iteration: 1343492310, states[0] = -94.989580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361259824, states[0] = -94.881659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383147678, states[0] = -70.431810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1404334081, states[0] = -94.943454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425239750, states[0] = -94.855231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445645608, states[0] = -67.618177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466752896, states[0] = -94.873086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487188702, states[0] = -94.760950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507975958, states[0] = -95.057605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528132066, states[0] = -95.178817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548602037, states[0] = 45.210546, states[40]= 0.072640
Saving checkpoint... 
Iteration: 1568804643, states[0] = -43.336700, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1589385904, states[0] = -95.259191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609613952, states[0] = -54.910794, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1630375943, states[0] = -95.104325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650870767, states[0] = -95.250591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671171824, states[0] = -95.094859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691829344, states[0] = -76.966723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712302957, states[0] = -95.162962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733079364, states[0] = -95.258241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753362504, states[0] = -95.068980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773855902, states[0] = -95.236941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794355669, states[0] = 4.129688, states[40]= 0.005330
Saving checkpoint... 
Iteration: 1814614438, states[0] = -36.657252, states[40]= 0.000214
Saving checkpoint... 
Iteration: 1836275656, states[0] = -94.923075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856563385, states[0] = 5.644549, states[40]= 0.004803
Saving checkpoint... 
Iteration: 1877252825, states[0] = -94.880006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896939622, states[0] = -94.984555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917432967, states[0] = -94.981291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937282391, states[0] = -94.906342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957739989, states[0] = -94.855862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978134408, states[0] = -54.449084, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1997723609, states[0] = -94.829623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018223367, states[0] = -94.829102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034104044, states[0] = -23.921014, states[40]= 0.000759
Saving checkpoint... 
Iteration: 2055238377, states[0] = -94.852800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075800406, states[0] = -94.920532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096213223, states[0] = -94.810884, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.865862
 - CaMKt in component CaMK (millimolar): 0.006992
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.591117
 - nass in component intracellular_ions (millimolar): 6.591177
 - ki in component intracellular_ions (millimolar): 145.385692
 - kss in component intracellular_ions (millimolar): 145.385673
 - cansr in component intracellular_ions (millimolar): 1.315451
 - cajsr in component intracellular_ions (millimolar): 1.277559
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003632
 - hf in component INa (dimensionless): 0.879375
 - hs in component INa (dimensionless): 0.879370
 - j in component INa (dimensionless): 0.879341
 - hsp in component INa (dimensionless): 0.724651
 - jp in component INa (dimensionless): 0.879321
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709124
 - hLp in component INaL (dimensionless): 0.451399
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621757
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.696635
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935510
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001620
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332079
 - xs1 in component IKs (dimensionless): 0.240313
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997347
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:55:54 (6360): called boinc_finish(0)

</stderr_txt>
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