𝕏

Task 55775476

Name HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_333-conf_700_0
Workunit 26485883
Created 2 Jul 2024, 14:10:14 UTC
Sent 2 Jul 2024, 22:56:42 UTC
Report deadline 5 Jul 2024, 22:56:42 UTC
Received 3 Jul 2024, 15:53:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238573
Run time 2 hours 12 min 14 sec
CPU time 1 hours 46 min
Validate state Valid
Credit 45.00
Device peak FLOPS 3.31 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.22 MB
Peak swap size 5.16 MB
Peak disk usage 0.12 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_333-conf_700.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_333-conf_700_0_r851749519_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702160945312556_ORdGradInc_k_26-Pieske_333-conf_700_0_r851749519_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.993231
     * GNaL_b in INaL: 0.005694
     * Gto_b in Ito: 0.085057
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032114
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.162249
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.439621
     * GKb_b in IKb: 0.003781
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035698
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8572370, states[0] = -33.933043, states[40]= 0.000284
Saving checkpoint... 
Iteration: 19564561, states[0] = -24.340767, states[40]= 0.000829
Saving checkpoint... 
Iteration: 30869211, states[0] = 7.172903, states[40]= 0.007113
Saving checkpoint... 
Iteration: 41936450, states[0] = -84.176270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53174337, states[0] = 21.307460, states[40]= 0.026139
Saving checkpoint... 
Iteration: 64296228, states[0] = -87.709791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73027281, states[0] = 10.143851, states[40]= 0.007558
Saving checkpoint... 
Iteration: 84200044, states[0] = 4.834620, states[40]= 0.006847
Saving checkpoint... 
Iteration: 95615695, states[0] = -87.654835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106684545, states[0] = 13.920294, states[40]= 0.008266
Saving checkpoint... 
Iteration: 118152942, states[0] = -87.810745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121311232, states[0] = -87.787850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133614952, states[0] = -87.678265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144614727, states[0] = -87.683545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155880976, states[0] = -20.332709, states[40]= 0.001228
Saving checkpoint... 
Iteration: 167310736, states[0] = -87.800539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178419700, states[0] = -81.137550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189724368, states[0] = -39.154244, states[40]= 0.000179
Saving checkpoint... 
Iteration: 200994006, states[0] = 20.844378, states[40]= 0.021599
Saving checkpoint... 
Iteration: 212300978, states[0] = -87.785009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223363730, states[0] = -5.927229, states[40]= 0.004487
Saving checkpoint... 
Iteration: 234738962, states[0] = -67.128598, states[40]= 0.000003
Saving checkpoint... 
Iteration: 246080606, states[0] = -82.424688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257333309, states[0] = 15.527052, states[40]= 0.008799
Saving checkpoint... 
Iteration: 268518186, states[0] = 2.057332, states[40]= 0.006414
Saving checkpoint... 
Iteration: 279697645, states[0] = -14.227806, states[40]= 0.002214
Saving checkpoint... 
Iteration: 290650394, states[0] = 21.337347, states[40]= 0.026982
Saving checkpoint... 
Iteration: 301776008, states[0] = -87.729824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313217825, states[0] = -47.244841, states[40]= 0.000057
Saving checkpoint... 
Iteration: 324385920, states[0] = -50.849993, states[40]= 0.000034
Saving checkpoint... 
Iteration: 335572748, states[0] = -83.618640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346797179, states[0] = -87.812585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358069012, states[0] = -81.943534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369299335, states[0] = 34.104703, states[40]= 0.115670
Saving checkpoint... 
Iteration: 380568766, states[0] = -84.105444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391675766, states[0] = -0.989662, states[40]= 0.005802
Saving checkpoint... 
Iteration: 402965604, states[0] = 25.776161, states[40]= 0.105600
Saving checkpoint... 
Iteration: 414267827, states[0] = -87.741199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425569624, states[0] = -86.851029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436814845, states[0] = 15.807672, states[40]= 0.008924
Saving checkpoint... 
Iteration: 447818150, states[0] = 13.278482, states[40]= 0.008113
Saving checkpoint... 
Iteration: 458964208, states[0] = 22.425994, states[40]= 0.045677
Saving checkpoint... 
Iteration: 470217461, states[0] = -70.600730, states[40]= 0.000002
Saving checkpoint... 
Iteration: 481555689, states[0] = -80.636128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492570696, states[0] = -87.576652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503900247, states[0] = -87.476342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515054838, states[0] = -83.654711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526462296, states[0] = 20.525236, states[40]= 0.019009
Saving checkpoint... 
Iteration: 537714021, states[0] = -76.339900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 549005002, states[0] = -15.583917, states[40]= 0.001937
Saving checkpoint... 
Iteration: 560365286, states[0] = -55.124490, states[40]= 0.000017
Saving checkpoint... 
Iteration: 571548952, states[0] = -83.416912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582671841, states[0] = -20.647639, states[40]= 0.001193
Saving checkpoint... 
Iteration: 593990427, states[0] = -2.608373, states[40]= 0.005410
Saving checkpoint... 
Iteration: 605062686, states[0] = -87.635252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616387016, states[0] = -87.334347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627595602, states[0] = -87.793043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638907940, states[0] = -87.725390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649779035, states[0] = 22.170535, states[40]= 0.040551
Saving checkpoint... 
Iteration: 661122005, states[0] = 17.724658, states[40]= 0.010325
Saving checkpoint... 
Iteration: 672310235, states[0] = 2.847810, states[40]= 0.006548
Saving checkpoint... 
Iteration: 683571470, states[0] = -87.730517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694693967, states[0] = -68.816927, states[40]= 0.000002
Saving checkpoint... 
Iteration: 705679098, states[0] = -47.979339, states[40]= 0.000052
Saving checkpoint... 
Iteration: 716980800, states[0] = -5.649460, states[40]= 0.004568
Saving checkpoint... 
Iteration: 728122618, states[0] = 13.776838, states[40]= 0.008231
Saving checkpoint... 
Iteration: 739414945, states[0] = -87.784378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750583310, states[0] = -87.792817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761652747, states[0] = -18.937250, states[40]= 0.001398
Saving checkpoint... 
Iteration: 772757703, states[0] = 40.435210, states[40]= 0.067350
Saving checkpoint... 
Iteration: 784073161, states[0] = -87.771754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795176614, states[0] = -57.290738, states[40]= 0.000012
Saving checkpoint... 
Iteration: 806412043, states[0] = -87.795611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817490859, states[0] = -33.542732, states[40]= 0.000356
Saving checkpoint... 
Iteration: 828710145, states[0] = -87.664872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839813366, states[0] = -21.464421, states[40]= 0.001109
Saving checkpoint... 
Iteration: 850898661, states[0] = -87.767906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861970142, states[0] = -10.598537, states[40]= 0.003117
Saving checkpoint... 
Iteration: 873204018, states[0] = -87.650802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884044854, states[0] = -87.703030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895241725, states[0] = -87.810152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906074373, states[0] = -87.811210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916987336, states[0] = -42.433476, states[40]= 0.000114
Saving checkpoint... 
Iteration: 928108913, states[0] = 9.769891, states[40]= 0.007512
Saving checkpoint... 
Iteration: 939196441, states[0] = -87.640634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950456547, states[0] = -4.582612, states[40]= 0.004876
Saving checkpoint... 
Iteration: 961571759, states[0] = 41.270022, states[40]= 0.044439
Saving checkpoint... 
Iteration: 972749432, states[0] = 21.116733, states[40]= 0.024339
Saving checkpoint... 
Iteration: 983969287, states[0] = -26.667920, states[40]= 0.000706
Saving checkpoint... 
Iteration: 995178955, states[0] = -86.758865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003371821, states[0] = -87.726113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014747330, states[0] = 20.318757, states[40]= 0.017638
Saving checkpoint... 
Iteration: 1025855241, states[0] = -87.648891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037114585, states[0] = -4.626546, states[40]= 0.004864
Saving checkpoint... 
Iteration: 1048155188, states[0] = -63.200775, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1059383519, states[0] = -87.785735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070355605, states[0] = -87.683395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081535831, states[0] = -87.745541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092708222, states[0] = -87.769058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103882818, states[0] = -87.796872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115047404, states[0] = -87.794073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126081181, states[0] = 14.729467, states[40]= 0.008503
Saving checkpoint... 
Iteration: 1137342951, states[0] = -87.636564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148416327, states[0] = 12.308033, states[40]= 0.007914
Saving checkpoint... 
Iteration: 1158069534, states[0] = 18.998665, states[40]= 0.012439
Saving checkpoint... 
Iteration: 1169174068, states[0] = -87.647096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180279161, states[0] = -21.245751, states[40]= 0.001131
Saving checkpoint... 
Iteration: 1191169734, states[0] = -87.620650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202426433, states[0] = 0.550004, states[40]= 0.006132
Saving checkpoint... 
Iteration: 1213447100, states[0] = -27.743691, states[40]= 0.000641
Saving checkpoint... 
Iteration: 1224527574, states[0] = -87.766212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235887843, states[0] = 21.858567, states[40]= 0.034822
Saving checkpoint... 
Iteration: 1247145376, states[0] = -80.032559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258321599, states[0] = -87.195735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269485831, states[0] = -86.980285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280460848, states[0] = -56.451715, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1291519028, states[0] = -87.759930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302781066, states[0] = -41.020985, states[40]= 0.000139
Saving checkpoint... 
Iteration: 1313895206, states[0] = 15.027684, states[40]= 0.008605
Saving checkpoint... 
Iteration: 1325013868, states[0] = -87.753650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336131210, states[0] = -71.204770, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1347359006, states[0] = -87.798038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358558390, states[0] = 14.466485, states[40]= 0.008420
Saving checkpoint... 
Iteration: 1369939923, states[0] = -39.507949, states[40]= 0.000170
Saving checkpoint... 
Iteration: 1380515937, states[0] = -87.778727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391758399, states[0] = -21.796591, states[40]= 0.001077
Saving checkpoint... 
Iteration: 1402904644, states[0] = 2.140161, states[40]= 0.006428
Saving checkpoint... 
Iteration: 1414072433, states[0] = 0.075384, states[40]= 0.006034
Saving checkpoint... 
Iteration: 1425079898, states[0] = -9.794571, states[40]= 0.003343
Saving checkpoint... 
Iteration: 1436437191, states[0] = -44.947411, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1447577473, states[0] = -9.559958, states[40]= 0.003411
Saving checkpoint... 
Iteration: 1458815010, states[0] = -87.672396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470001877, states[0] = -87.761967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480874320, states[0] = 17.252240, states[40]= 0.009854
Saving checkpoint... 
Iteration: 1491890629, states[0] = 6.334393, states[40]= 0.007056
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.690496
 - CaMKt in component CaMK (millimolar): 0.042348
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.034534
 - nass in component intracellular_ions (millimolar): 7.034682
 - ki in component intracellular_ions (millimolar): 144.885821
 - kss in component intracellular_ions (millimolar): 144.885789
 - cansr in component intracellular_ions (millimolar): 1.619281
 - cajsr in component intracellular_ions (millimolar): 1.187486
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007484
 - hf in component INa (dimensionless): 0.691588
 - hs in component INa (dimensionless): 0.691349
 - j in component INa (dimensionless): 0.680891
 - hsp in component INa (dimensionless): 0.446327
 - jp in component INa (dimensionless): 0.654539
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.293185
 - hLp in component INaL (dimensionless): 0.136252
 - a in component Ito (dimensionless): 0.001014
 - iF in component Ito (dimensionless): 0.999539
 - iS in component Ito (dimensionless): 0.176148
 - ap in component Ito (dimensionless): 0.000517
 - iFp in component Ito (dimensionless): 0.999539
 - iSp in component Ito (dimensionless): 0.213260
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.805100
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.967184
 - jca in component ICaL (dimensionless): 0.948286
 - ffp in component ICaL (dimensionless): 0.999867
 - fcafp in component ICaL (dimensionless): 0.999992
 - nca in component ICaL (dimensionless): 0.009446
 - xrf in component IKr (dimensionless): 0.028345
 - xrs in component IKr (dimensionless): 0.785151
 - xs1 in component IKs (dimensionless): 0.457911
 - xs2 in component IKs (dimensionless): 0.001172
 - xk1 in component IK1 (dimensionless): 0.996814
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:52:46 (3544): called boinc_finish(0)

</stderr_txt>
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