𝕏

Task 55771941

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_2000-conf_292_0
Workunit 26484118
Created 2 Jul 2024, 14:08:18 UTC
Sent 2 Jul 2024, 22:14:08 UTC
Report deadline 5 Jul 2024, 22:14:08 UTC
Received 5 Jul 2024, 16:46:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241950
Run time 2 hours 51 min 16 sec
CPU time 39 min 12 sec
Validate state Valid
Credit 46.69
Device peak FLOPS 5.64 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.27 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_2000-conf_292.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_2000-conf_292_0_r2145067602_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_2000-conf_292_0_r2145067602_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.921484
     * GNaL_b in INaL: 0.005936
     * Gto_b in Ito: 0.088077
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032242
     * GKs_b in IKs: 0.001933
     * GK1_b in IK1: 0.159636
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.605619
     * GKb_b in IKb: 0.003768
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035467
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8349850, states[0] = -94.308272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14790292, states[0] = -94.362211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20395753, states[0] = -94.287789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27989235, states[0] = -94.318915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34801458, states[0] = -94.325915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40123652, states[0] = -20.239757, states[40]= 0.000290
Saving checkpoint... 
Iteration: 47723968, states[0] = -94.333878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56786923, states[0] = -94.336353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63573846, states[0] = -94.344933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70003225, states[0] = 13.556868, states[40]= 1.501261
Saving checkpoint... 
Iteration: 78123592, states[0] = -22.777067, states[40]= 0.000438
Saving checkpoint... 
Iteration: 86141589, states[0] = -43.691883, states[40]= 0.000271
Saving checkpoint... 
Iteration: 93543635, states[0] = -94.357447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102162571, states[0] = -69.963579, states[40]= 0.000010
Saving checkpoint... 
Iteration: 109873312, states[0] = -94.354900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119703099, states[0] = -94.366316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125560191, states[0] = -94.366201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132025380, states[0] = 24.528535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140350350, states[0] = -94.261796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147769496, states[0] = -94.365757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153485669, states[0] = -94.356190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159166890, states[0] = -77.369904, states[40]= 0.000004
Saving checkpoint... 
Iteration: 166176412, states[0] = -90.895675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171908372, states[0] = -94.357820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178964699, states[0] = -94.354281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184046337, states[0] = 23.941883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188343019, states[0] = -94.252235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195211521, states[0] = -93.748173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202907244, states[0] = -94.357751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208342405, states[0] = -94.251051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214626178, states[0] = -94.370981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221666119, states[0] = -94.370414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226397054, states[0] = -94.312483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232662027, states[0] = -94.370257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238131290, states[0] = -32.743924, states[40]= 0.000573
Saving checkpoint... 
Iteration: 243157828, states[0] = -64.578026, states[40]= 0.000022
Saving checkpoint... 
Iteration: 248200174, states[0] = -93.655762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252081584, states[0] = 11.299153, states[40]= 0.000038
Saving checkpoint... 
Iteration: 258430624, states[0] = -94.333851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263688906, states[0] = -94.368702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270502241, states[0] = -94.358868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274893147, states[0] = -94.356958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279561495, states[0] = -94.366902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283871012, states[0] = -94.358117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288542669, states[0] = -94.364828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296485603, states[0] = -94.354141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303566070, states[0] = -94.366566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309736988, states[0] = -94.365328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315933703, states[0] = -94.353177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321921725, states[0] = -94.353766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327610859, states[0] = -94.367792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332394920, states[0] = -94.307810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337977242, states[0] = -94.349780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344721721, states[0] = -94.365024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352934895, states[0] = -94.352004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359283241, states[0] = -94.113159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365200978, states[0] = -93.659167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373357290, states[0] = -94.267530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379651698, states[0] = -94.366259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383968609, states[0] = -94.348954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387977683, states[0] = -94.348267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393455780, states[0] = -94.341514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399505749, states[0] = -94.355804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406395068, states[0] = -94.305723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412262867, states[0] = -94.037373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420916493, states[0] = -94.351157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427753170, states[0] = -94.360989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433835118, states[0] = -94.355963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439586330, states[0] = -94.363712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443856461, states[0] = -94.354311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451019322, states[0] = 23.419689, states[40]= -0.000000
Saving checkpoint... 
Iteration: 457392965, states[0] = -94.302447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463813402, states[0] = -94.356411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470528325, states[0] = -94.357582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476316182, states[0] = -94.195868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482515916, states[0] = -94.355250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488177844, states[0] = -91.810299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494025542, states[0] = 24.524263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498743986, states[0] = -94.359347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505796894, states[0] = -94.356160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510642298, states[0] = -94.362456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516171664, states[0] = -85.481920, states[40]= 0.000001
Saving checkpoint... 
Iteration: 522332545, states[0] = -94.225914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527208548, states[0] = -93.715691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532486438, states[0] = -94.347350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536673659, states[0] = -94.361114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541645982, states[0] = -94.361515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549423312, states[0] = -94.321159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554629732, states[0] = -94.361214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558443359, states[0] = -94.331318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566794007, states[0] = -94.354539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573992883, states[0] = -94.341786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580736580, states[0] = -94.357296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584137703, states[0] = -40.222423, states[40]= 0.000375
Saving checkpoint... 
Iteration: 590447214, states[0] = -94.332089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596317465, states[0] = -94.194957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603212940, states[0] = -93.746909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611080584, states[0] = 11.813568, states[40]= 0.000034
Saving checkpoint... 
Iteration: 618669233, states[0] = -94.358792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626195875, states[0] = -93.604425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631393489, states[0] = -94.297695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639631207, states[0] = -94.358676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646444188, states[0] = -94.329063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652601101, states[0] = -94.357904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659607911, states[0] = -94.357861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666729395, states[0] = -94.355081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672808526, states[0] = -94.350492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680249293, states[0] = -93.968051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685640244, states[0] = -94.357269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691810749, states[0] = -94.349785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698179228, states[0] = -92.377469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704120348, states[0] = -20.520569, states[40]= 0.000396
Saving checkpoint... 
Iteration: 710049629, states[0] = 23.299269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714645139, states[0] = -94.356365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720993594, states[0] = -94.337348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727016794, states[0] = 22.784437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734690560, states[0] = -94.354681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739001170, states[0] = 40.664826, states[40]= 0.770658
Saving checkpoint... 
Iteration: 747425230, states[0] = -94.316344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752997942, states[0] = -94.336118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759764428, states[0] = -94.350480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765546224, states[0] = -94.351039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772104191, states[0] = -3.507000, states[40]= 0.000356
Saving checkpoint... 
Iteration: 778450036, states[0] = -94.327683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789376673, states[0] = -94.277369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799490216, states[0] = -94.340356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810365030, states[0] = -94.263965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819166199, states[0] = -76.373002, states[40]= 0.000004
Saving checkpoint... 
Iteration: 827742311, states[0] = -94.349629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835886308, states[0] = -94.340709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845458362, states[0] = -94.329022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854938304, states[0] = -94.336811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867820101, states[0] = -94.343957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878765640, states[0] = -94.346855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887765079, states[0] = -94.346617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898712711, states[0] = -94.348911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909558448, states[0] = -94.347912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919591783, states[0] = -94.349637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931931709, states[0] = -94.334950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942960928, states[0] = -94.332768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955305503, states[0] = -94.157242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966070772, states[0] = 16.414210, states[40]= 0.000009
Saving checkpoint... 
Iteration: 979242814, states[0] = -93.925822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990524285, states[0] = -94.341493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005586793, states[0] = -94.346876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017079230, states[0] = 12.499001, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1027232507, states[0] = -93.865927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035404849, states[0] = -94.294514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047794803, states[0] = -94.340141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057115659, states[0] = -15.255192, states[40]= 0.000367
Saving checkpoint... 
Iteration: 1066988315, states[0] = -94.327349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076313469, states[0] = -94.171951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084251444, states[0] = -93.966127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091224183, states[0] = -93.811239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101298906, states[0] = -94.136191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108227427, states[0] = -93.831876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117308535, states[0] = -94.159554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124630650, states[0] = -94.344217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130837409, states[0] = -94.335032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138584111, states[0] = -94.342778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146530348, states[0] = -94.337725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153915193, states[0] = -94.329378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161937209, states[0] = -94.327729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169185060, states[0] = -93.329239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176942554, states[0] = -94.326937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184577909, states[0] = -94.341083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192195887, states[0] = -93.586809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197926362, states[0] = -94.327349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204799503, states[0] = -94.335171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211182119, states[0] = -93.031498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217465426, states[0] = -94.320500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224085450, states[0] = 9.249464, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1229587014, states[0] = -94.340194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235893991, states[0] = -94.328281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243240364, states[0] = -93.904496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258948081, states[0] = -94.324140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289344643, states[0] = -94.222438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321213739, states[0] = -93.730682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352951597, states[0] = -94.321126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384663358, states[0] = -94.336102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416488029, states[0] = -94.321404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448526448, states[0] = -94.328160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481111832, states[0] = -11.013935, states[40]= 0.000396
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.189641
 - CaMKt in component CaMK (millimolar): 0.007321
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 7.433383
 - nass in component intracellular_ions (millimolar): 7.433530
 - ki in component intracellular_ions (millimolar): 144.064129
 - kss in component intracellular_ions (millimolar): 144.064106
 - cansr in component intracellular_ions (millimolar): 2.617130
 - cajsr in component intracellular_ions (millimolar): 2.618130
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.003888
 - hf in component INa (dimensionless): 0.867082
 - hs in component INa (dimensionless): 0.867085
 - j in component INa (dimensionless): 0.867099
 - hsp in component INa (dimensionless): 0.701979
 - jp in component INa (dimensionless): 0.867107
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709979
 - hLp in component INaL (dimensionless): 0.501720
 - a in component Ito (dimensionless): 0.000654
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.999852
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999852
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.974886
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005522
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.091492
 - xs1 in component IKs (dimensionless): 0.127906
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997518
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:46:21 (13812): called boinc_finish(0)

</stderr_txt>
]]>


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