𝕏

Task 55771098

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_90_0
Workunit 26483697
Created 2 Jul 2024, 14:07:52 UTC
Sent 2 Jul 2024, 21:45:24 UTC
Report deadline 6 Jul 2024, 7:21:24 UTC
Received 4 Jul 2024, 12:56:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214039
Run time 1 hours 27 min 42 sec
CPU time 51 min 28 sec
Validate state Valid
Credit 65.72
Device peak FLOPS 3.77 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.74 MB
Peak swap size 5.30 MB
Peak disk usage 0.21 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_90.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_90_0_r6717416_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_90_0_r6717416_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.156501
     * GNaL_b in INaL: 0.005924
     * Gto_b in Ito: 0.087246
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031952
     * GKs_b in IKs: 0.001907
     * GK1_b in IK1: 0.166530
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.677175
     * GKb_b in IKb: 0.003819
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035428
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10548073, states[0] = 11.082228, states[40]= 0.004940
Saving checkpoint... 
Iteration: 26905679, states[0] = -95.086097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43340711, states[0] = -95.042597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54614863, states[0] = -34.343417, states[40]= 0.000284
Saving checkpoint... 
Iteration: 68457652, states[0] = -95.064046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82776765, states[0] = -94.978430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97399998, states[0] = -95.043889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112935073, states[0] = -95.050611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128076195, states[0] = -0.211689, states[40]= 0.004203
Saving checkpoint... 
Iteration: 143456224, states[0] = -95.052628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159042364, states[0] = 14.503189, states[40]= 0.005095
Saving checkpoint... 
Iteration: 175095480, states[0] = -14.898954, states[40]= 0.001475
Saving checkpoint... 
Iteration: 191276464, states[0] = -94.970142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207108094, states[0] = -26.743808, states[40]= 0.000627
Saving checkpoint... 
Iteration: 218297800, states[0] = -94.988460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235690086, states[0] = -94.838303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253777786, states[0] = -94.971084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272071633, states[0] = 2.311180, states[40]= 0.004487
Saving checkpoint... 
Iteration: 290346508, states[0] = -95.018314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308294262, states[0] = -94.985457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325905255, states[0] = -95.039943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344058436, states[0] = 8.313525, states[40]= 0.004833
Saving checkpoint... 
Iteration: 361960933, states[0] = -95.051915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379644703, states[0] = -65.183848, states[40]= 0.000002
Saving checkpoint... 
Iteration: 397579456, states[0] = -2.094369, states[40]= 0.003919
Saving checkpoint... 
Iteration: 410534441, states[0] = 17.252437, states[40]= 0.005516
Saving checkpoint... 
Iteration: 428820093, states[0] = -95.003709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446383577, states[0] = -95.033220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464292172, states[0] = -94.983641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477747092, states[0] = -94.936501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491447264, states[0] = -95.049430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510168317, states[0] = -94.265221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527866260, states[0] = -95.026801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542227043, states[0] = -94.907454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560300660, states[0] = -94.990274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578372077, states[0] = -95.029023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596827063, states[0] = -95.007793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615306825, states[0] = -94.994755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633564616, states[0] = 5.656606, states[40]= 0.004725
Saving checkpoint... 
Iteration: 652752710, states[0] = -94.943514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671293243, states[0] = -94.984381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688854642, states[0] = -95.021800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707148697, states[0] = -70.592090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 725964150, states[0] = -95.052194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744302489, states[0] = -94.991522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763089698, states[0] = -9.678211, states[40]= 0.002391
Saving checkpoint... 
Iteration: 781344475, states[0] = -95.016984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800183631, states[0] = -94.820852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818670202, states[0] = -94.505997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836981942, states[0] = -95.054736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855302436, states[0] = -94.991409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873934566, states[0] = -95.046660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890359262, states[0] = -95.023679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906303596, states[0] = -94.992232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922240985, states[0] = -94.927981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938803618, states[0] = -94.992227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950496554, states[0] = -95.056503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966250908, states[0] = -94.941065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984639619, states[0] = -59.048157, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1002186045, states[0] = -94.827915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020263018, states[0] = -94.955329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037824179, states[0] = -95.005801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056045866, states[0] = 13.229112, states[40]= 0.005002
Saving checkpoint... 
Iteration: 1074133031, states[0] = -51.668449, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1093001155, states[0] = 49.051133, states[40]= 0.038194
Saving checkpoint... 
Iteration: 1112541286, states[0] = 14.905430, states[40]= 0.005133
Saving checkpoint... 
Iteration: 1131998902, states[0] = -95.056656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152613445, states[0] = -31.798879, states[40]= 0.000388
Saving checkpoint... 
Iteration: 1173506653, states[0] = 24.972290, states[40]= 0.114408
Saving checkpoint... 
Iteration: 1192501763, states[0] = 46.476735, states[40]= 0.077177
Saving checkpoint... 
Iteration: 1211221248, states[0] = -94.897513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228957115, states[0] = -95.050703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247776367, states[0] = -94.969011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254833266, states[0] = -95.010859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274419283, states[0] = -95.042944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293881984, states[0] = -95.032119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308868411, states[0] = -95.027136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329129432, states[0] = -47.779641, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1348978117, states[0] = -95.053874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368546550, states[0] = 12.973819, states[40]= 0.004988
Saving checkpoint... 
Iteration: 1386856894, states[0] = -95.022332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406565142, states[0] = 5.419992, states[40]= 0.004713
Saving checkpoint... 
Iteration: 1419489402, states[0] = -95.055325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439467656, states[0] = -95.052276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453863808, states[0] = -95.025203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473511817, states[0] = 22.406160, states[40]= 0.034784
Saving checkpoint... 
Iteration: 1492617252, states[0] = -35.447462, states[40]= 0.000247
Saving checkpoint... 
Iteration: 1506617147, states[0] = 21.969695, states[40]= 0.015295
Saving checkpoint... 
Iteration: 1526364604, states[0] = -95.272591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546082320, states[0] = -95.165269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560323545, states[0] = 19.639852, states[40]= 0.008673
Saving checkpoint... 
Iteration: 1580179752, states[0] = -15.410566, states[40]= 0.001586
Saving checkpoint... 
Iteration: 1599716295, states[0] = -57.053727, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1619139528, states[0] = 12.826723, states[40]= 0.006048
Saving checkpoint... 
Iteration: 1638626143, states[0] = 18.597955, states[40]= 0.007771
Saving checkpoint... 
Iteration: 1658342436, states[0] = -95.280585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677618919, states[0] = 21.003690, states[40]= 0.012006
Saving checkpoint... 
Iteration: 1696933460, states[0] = -84.113749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716281761, states[0] = -95.317723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735621393, states[0] = -63.983123, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1750990077, states[0] = -95.198953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1766966824, states[0] = -95.305570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783439863, states[0] = -95.277906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794950129, states[0] = 7.417582, states[40]= 0.005543
Saving checkpoint... 
Iteration: 1812234346, states[0] = -94.961871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830199564, states[0] = -94.885282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847850171, states[0] = -95.035839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865780686, states[0] = -94.982656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883446577, states[0] = -95.054198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901300468, states[0] = -94.992685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919071160, states[0] = 2.496976, states[40]= 0.004506
Saving checkpoint... 
Iteration: 1936822537, states[0] = -95.005387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954635267, states[0] = -54.187525, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1970937516, states[0] = -95.046940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988761132, states[0] = -94.952789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008477242, states[0] = -95.053407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2026585897, states[0] = -6.587567, states[40]= 0.003048
Saving checkpoint... 
Iteration: 2044067953, states[0] = 4.118472, states[40]= 0.004633
Saving checkpoint... 
Iteration: 2057634208, states[0] = -52.961960, states[40]= 0.000017
Saving checkpoint... 
Iteration: 2075232554, states[0] = -94.914957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093224274, states[0] = -94.901906, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.931972
 - CaMKt in component CaMK (millimolar): 0.007044
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.602282
 - nass in component intracellular_ions (millimolar): 6.602342
 - ki in component intracellular_ions (millimolar): 145.374432
 - kss in component intracellular_ions (millimolar): 145.374412
 - cansr in component intracellular_ions (millimolar): 1.314915
 - cajsr in component intracellular_ions (millimolar): 1.276806
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003608
 - hf in component INa (dimensionless): 0.880522
 - hs in component INa (dimensionless): 0.880518
 - j in component INa (dimensionless): 0.880490
 - hsp in component INa (dimensionless): 0.726815
 - jp in component INa (dimensionless): 0.880471
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710693
 - hLp in component INaL (dimensionless): 0.452849
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621137
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696086
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935313
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001610
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329699
 - xs1 in component IKs (dimensionless): 0.242115
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997329
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:55:31 (20552): called boinc_finish(0)

</stderr_txt>
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