𝕏

Task 55770412

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Coppini_2000-conf_489_0
Workunit 26483354
Created 2 Jul 2024, 14:07:27 UTC
Sent 2 Jul 2024, 21:42:59 UTC
Report deadline 5 Jul 2024, 21:42:59 UTC
Received 3 Jul 2024, 16:27:55 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240196
Run time 1 hours 7 min 51 sec
CPU time 1 hours 7 min 44 sec
Validate state Valid
Credit 45.05
Device peak FLOPS 3.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 7.00 MB
Peak swap size 1.69 MB
Peak disk usage 0.63 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Coppini_2000-conf_489.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Coppini_2000-conf_489_0_r1690213194_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Coppini_2000-conf_489_0_r1690213194_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.776597
     * GNaL_b in INaL: 0.005558
     * Gto_b in Ito: 0.083872
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032118
     * GKs_b in IKs: 0.001917
     * GK1_b in IK1: 0.160859
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.493518
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030082
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8219297, states[0] = -94.434468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20229632, states[0] = -94.339891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32204253, states[0] = -94.174951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43850922, states[0] = -94.645806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55486407, states[0] = -94.608000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67331774, states[0] = -94.490304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79157793, states[0] = -55.114964, states[40]= 0.000041
Saving checkpoint... 
Iteration: 90968156, states[0] = -94.620179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103542362, states[0] = -94.606402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116122299, states[0] = -22.837172, states[40]= 0.001326
Saving checkpoint... 
Iteration: 128859998, states[0] = -94.617742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139750254, states[0] = -94.617945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151950053, states[0] = -94.614387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164082583, states[0] = 6.520563, states[40]= 0.004491
Saving checkpoint... 
Iteration: 176346770, states[0] = -94.495372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188601125, states[0] = -94.609736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200791426, states[0] = -94.616141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210051594, states[0] = 18.933168, states[40]= 0.002759
Saving checkpoint... 
Iteration: 222153793, states[0] = -50.605535, states[40]= 0.000085
Saving checkpoint... 
Iteration: 234223443, states[0] = -94.205404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242700034, states[0] = -94.615070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255132883, states[0] = -31.736946, states[40]= 0.000984
Saving checkpoint... 
Iteration: 267449651, states[0] = -94.572788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279666664, states[0] = -94.613739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291907615, states[0] = -94.613710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304158319, states[0] = -54.893947, states[40]= 0.000043
Saving checkpoint... 
Iteration: 316399841, states[0] = -94.544035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328730090, states[0] = -94.615363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341104756, states[0] = -7.335304, states[40]= 0.003112
Saving checkpoint... 
Iteration: 353172483, states[0] = -69.593376, states[40]= 0.000004
Saving checkpoint... 
Iteration: 365494235, states[0] = -94.589009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378167628, states[0] = -64.146013, states[40]= 0.000009
Saving checkpoint... 
Iteration: 391054190, states[0] = 18.073899, states[40]= 0.002934
Saving checkpoint... 
Iteration: 403721996, states[0] = -94.615096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416221460, states[0] = -94.197107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428730993, states[0] = -94.615176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441131416, states[0] = -30.466653, states[40]= 0.001085
Saving checkpoint... 
Iteration: 453515396, states[0] = -94.594554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465710294, states[0] = -94.614764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474200458, states[0] = -93.994056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486618270, states[0] = -94.610221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498693205, states[0] = -94.614270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511164798, states[0] = -61.226922, states[40]= 0.000015
Saving checkpoint... 
Iteration: 523564540, states[0] = -94.603960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536159159, states[0] = -55.697229, states[40]= 0.000038
Saving checkpoint... 
Iteration: 548357457, states[0] = -94.506045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560157738, states[0] = -54.335681, states[40]= 0.000047
Saving checkpoint... 
Iteration: 572151350, states[0] = -48.289839, states[40]= 0.000122
Saving checkpoint... 
Iteration: 583991408, states[0] = -94.610982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595565492, states[0] = -94.603969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607238253, states[0] = -94.259165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618934594, states[0] = -94.612415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630723334, states[0] = -94.614694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642701225, states[0] = -94.614224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654458909, states[0] = -94.576002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666188197, states[0] = -90.596498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678058253, states[0] = 16.671303, states[40]= 0.003212
Saving checkpoint... 
Iteration: 689983879, states[0] = -94.610991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701900663, states[0] = -94.613073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714371008, states[0] = -94.519432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726918262, states[0] = -94.612615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739467794, states[0] = -94.579376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751579247, states[0] = -94.605596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763712472, states[0] = -94.614255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775428861, states[0] = -94.561423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787060761, states[0] = 15.771385, states[40]= 0.003383
Saving checkpoint... 
Iteration: 799199295, states[0] = -93.940894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811341101, states[0] = -94.486427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823052874, states[0] = 18.515090, states[40]= 0.002846
Saving checkpoint... 
Iteration: 834890707, states[0] = -94.613047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847139767, states[0] = -37.733592, states[40]= 0.000522
Saving checkpoint... 
Iteration: 859140572, states[0] = -38.445956, states[40]= 0.000478
Saving checkpoint... 
Iteration: 870711262, states[0] = -94.614032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882647274, states[0] = -94.611558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894557676, states[0] = -94.602200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906755702, states[0] = -94.614480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919037418, states[0] = 23.235222, states[40]= 0.001955
Saving checkpoint... 
Iteration: 931244949, states[0] = -94.281268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943491615, states[0] = -94.587140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952189665, states[0] = -91.648385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964891698, states[0] = -94.612784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977770713, states[0] = -94.614367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990251910, states[0] = -94.303393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002729181, states[0] = -94.614087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015136641, states[0] = -34.990337, states[40]= 0.000718
Saving checkpoint... 
Iteration: 1027573215, states[0] = -94.604277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040052018, states[0] = 18.798667, states[40]= 0.002788
Saving checkpoint... 
Iteration: 1052496118, states[0] = -94.588284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065000848, states[0] = 45.290779, states[40]= 0.091820
Saving checkpoint... 
Iteration: 1077472320, states[0] = -94.580438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089875073, states[0] = -94.612902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102303006, states[0] = -94.427233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114698845, states[0] = -94.613286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126855964, states[0] = -94.613198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139218010, states[0] = -94.181786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151582022, states[0] = -94.605209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164026485, states[0] = 25.806257, states[40]= 0.001724
Saving checkpoint... 
Iteration: 1176382248, states[0] = -94.528652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188694282, states[0] = -94.613022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201334293, states[0] = -94.476786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213598014, states[0] = -94.606946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225825880, states[0] = -94.613487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238060564, states[0] = 15.843377, states[40]= 0.003370
Saving checkpoint... 
Iteration: 1250250421, states[0] = -94.298265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262506426, states[0] = -94.590768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274774810, states[0] = -94.613810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286987929, states[0] = -94.609773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299344108, states[0] = -94.489267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311622595, states[0] = -94.609048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323843022, states[0] = -94.613053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334181423, states[0] = -82.026105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346676276, states[0] = -94.612116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359094631, states[0] = -0.100240, states[40]= 0.004360
Saving checkpoint... 
Iteration: 1371440869, states[0] = -94.566537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383736504, states[0] = -94.613466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394427965, states[0] = -94.559780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407146868, states[0] = -44.125501, states[40]= 0.000223
Saving checkpoint... 
Iteration: 1419905643, states[0] = -94.611627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432521964, states[0] = -94.594289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445025077, states[0] = 26.054554, states[40]= 0.001792
Saving checkpoint... 
Iteration: 1457490280, states[0] = -94.585776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469999633, states[0] = -94.609112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482741025, states[0] = -94.613324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495405492, states[0] = -94.545779, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.484984
 - CaMKt in component CaMK (millimolar): 0.004207
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.524302
 - nass in component intracellular_ions (millimolar): 6.524389
 - ki in component intracellular_ions (millimolar): 145.387366
 - kss in component intracellular_ions (millimolar): 145.387351
 - cansr in component intracellular_ions (millimolar): 1.592426
 - cajsr in component intracellular_ions (millimolar): 1.591761
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003774
 - hf in component INa (dimensionless): 0.872576
 - hs in component INa (dimensionless): 0.872577
 - j in component INa (dimensionless): 0.872583
 - hsp in component INa (dimensionless): 0.712023
 - jp in component INa (dimensionless): 0.872587
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.717895
 - hLp in component INaL (dimensionless): 0.509695
 - a in component Ito (dimensionless): 0.000641
 - iF in component Ito (dimensionless): 0.999860
 - iS in component Ito (dimensionless): 0.892108
 - ap in component Ito (dimensionless): 0.000327
 - iFp in component Ito (dimensionless): 0.999860
 - iSp in component Ito (dimensionless): 0.931835
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975857
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002722
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.097723
 - xs1 in component IKs (dimensionless): 0.124030
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997444
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:42:37 (18740): called boinc_finish(0)

</stderr_txt>
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