𝕏

Task 55768740

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_2000-conf_286_0
Workunit 26482519
Created 2 Jul 2024, 14:06:39 UTC
Sent 2 Jul 2024, 21:30:48 UTC
Report deadline 5 Jul 2024, 21:30:48 UTC
Received 3 Jul 2024, 15:41:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233458
Run time 1 hours 54 min 40 sec
CPU time 1 hours 54 min 40 sec
Validate state Valid
Credit 45.46
Device peak FLOPS 3.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.60 MB
Peak swap size 6.21 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_2000-conf_286.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_2000-conf_286_0_r1386332482_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_2000-conf_286_0_r1386332482_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 99.966392
     * GNaL_b in INaL: 0.005545
     * Gto_b in Ito: 0.086365
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031705
     * GKs_b in IKs: 0.001886
     * GK1_b in IK1: 0.167513
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.245194
     * GKb_b in IKb: 0.003812
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030335
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5729249, states[0] = -94.351249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14201124, states[0] = -23.078379, states[40]= 0.006863
Saving checkpoint... 
Iteration: 22624092, states[0] = -94.305622, states[40]= 0.000001
Saving checkpoint... 
Iteration: 31022818, states[0] = 34.257408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39430880, states[0] = -94.210184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 47913935, states[0] = -94.340078, states[40]= 0.000001
Saving checkpoint... 
Iteration: 56511137, states[0] = -94.307828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 64935445, states[0] = -94.355210, states[40]= 0.000001
Saving checkpoint... 
Iteration: 73500553, states[0] = -94.317009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 82243479, states[0] = -67.163808, states[40]= 0.000085
Saving checkpoint... 
Iteration: 90847562, states[0] = -94.375077, states[40]= 0.000001
Saving checkpoint... 
Iteration: 99485595, states[0] = -94.321205, states[40]= 0.000001
Saving checkpoint... 
Iteration: 108198512, states[0] = -35.223938, states[40]= 0.005714
Saving checkpoint... 
Iteration: 116989285, states[0] = -94.375485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 125589548, states[0] = -94.372943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134273093, states[0] = -93.737647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142756571, states[0] = -94.388749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 151078117, states[0] = 21.687884, states[40]= 0.000007
Saving checkpoint... 
Iteration: 159543118, states[0] = -94.362068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 168061481, states[0] = 27.521694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 176118828, states[0] = 4.959822, states[40]= 0.000372
Saving checkpoint... 
Iteration: 184580677, states[0] = -94.374344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 193072616, states[0] = 23.671978, states[40]= 0.000003
Saving checkpoint... 
Iteration: 201457257, states[0] = -94.308522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 209776484, states[0] = -94.389607, states[40]= 0.000001
Saving checkpoint... 
Iteration: 218192841, states[0] = -33.530660, states[40]= 0.006554
Saving checkpoint... 
Iteration: 226779183, states[0] = -94.389175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 235184189, states[0] = -29.186120, states[40]= 0.008357
Saving checkpoint... 
Iteration: 243653721, states[0] = -94.385241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 252209176, states[0] = -43.883437, states[40]= 0.002300
Saving checkpoint... 
Iteration: 260631862, states[0] = -94.382263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 268998114, states[0] = -94.377709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 277368738, states[0] = -94.166598, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285939821, states[0] = -94.380495, states[40]= 0.000001
Saving checkpoint... 
Iteration: 294443284, states[0] = -94.291599, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302984436, states[0] = -94.377327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311375887, states[0] = -94.182287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 319901191, states[0] = -94.381376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 325150755, states[0] = -12.433023, states[40]= 0.001433
Saving checkpoint... 
Iteration: 333745829, states[0] = -94.385910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 342192514, states[0] = -33.410801, states[40]= 0.006608
Saving checkpoint... 
Iteration: 350730736, states[0] = -94.385207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 359133231, states[0] = -1.939435, states[40]= 0.000966
Saving checkpoint... 
Iteration: 367684977, states[0] = -94.383179, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376110819, states[0] = 8.360726, states[40]= 0.000196
Saving checkpoint... 
Iteration: 384461890, states[0] = -94.306946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 392946561, states[0] = -94.376221, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401493780, states[0] = -94.330925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 407025060, states[0] = 33.618547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415550578, states[0] = -94.358120, states[40]= 0.000001
Saving checkpoint... 
Iteration: 424091477, states[0] = 16.380791, states[40]= 0.000031
Saving checkpoint... 
Iteration: 432470864, states[0] = -94.312940, states[40]= 0.000001
Saving checkpoint... 
Iteration: 441211240, states[0] = -45.397943, states[40]= 0.001917
Saving checkpoint... 
Iteration: 449988779, states[0] = -94.371672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 458619236, states[0] = -94.373277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 467269391, states[0] = -93.704438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475875184, states[0] = -94.376932, states[40]= 0.000001
Saving checkpoint... 
Iteration: 484420512, states[0] = -94.256175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 493285477, states[0] = -93.819765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501880617, states[0] = -94.375703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 510473153, states[0] = -94.311903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 519218525, states[0] = -50.890845, states[40]= 0.000948
Saving checkpoint... 
Iteration: 527733832, states[0] = -94.378693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 536539257, states[0] = -94.349365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 545053690, states[0] = 29.814901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553458328, states[0] = -94.297363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562025119, states[0] = 33.623577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570518919, states[0] = -94.338994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 578996527, states[0] = -94.366434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587407892, states[0] = -94.233360, states[40]= 0.000001
Saving checkpoint... 
Iteration: 595956570, states[0] = -94.368132, states[40]= 0.000001
Saving checkpoint... 
Iteration: 604450935, states[0] = -94.288213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 613077146, states[0] = 21.979097, states[40]= 0.000006
Saving checkpoint... 
Iteration: 621593138, states[0] = -94.362411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 630098951, states[0] = 13.334755, states[40]= 0.000066
Saving checkpoint... 
Iteration: 638383849, states[0] = -94.187374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 646641106, states[0] = -94.369251, states[40]= 0.000001
Saving checkpoint... 
Iteration: 655284983, states[0] = -93.810409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663908861, states[0] = -94.368262, states[40]= 0.000001
Saving checkpoint... 
Iteration: 672316807, states[0] = -93.978566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680901952, states[0] = -94.367994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 689362737, states[0] = -94.135966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 697689836, states[0] = -94.371213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 706173349, states[0] = -24.416582, states[40]= 0.007545
Saving checkpoint... 
Iteration: 714628436, states[0] = -94.365141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 723272886, states[0] = -93.724854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731743378, states[0] = -94.371198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 740156080, states[0] = -15.778120, states[40]= 0.001786
Saving checkpoint... 
Iteration: 748416968, states[0] = -94.241245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756912060, states[0] = -94.364654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 765480313, states[0] = -94.307990, states[40]= 0.000001
Saving checkpoint... 
Iteration: 774065359, states[0] = 26.209684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 782460698, states[0] = -94.291047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 788271487, states[0] = -93.710970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796828154, states[0] = -94.367082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 805294318, states[0] = -93.860600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813720632, states[0] = -94.367956, states[40]= 0.000001
Saving checkpoint... 
Iteration: 822222625, states[0] = -54.092027, states[40]= 0.000609
Saving checkpoint... 
Iteration: 828175791, states[0] = -25.457056, states[40]= 0.008109
Saving checkpoint... 
Iteration: 836391482, states[0] = -94.195270, states[40]= 0.000001
Saving checkpoint... 
Iteration: 844851652, states[0] = -94.364374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 853660139, states[0] = -94.363508, states[40]= 0.000001
Saving checkpoint... 
Iteration: 862412813, states[0] = -94.230827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867821190, states[0] = -94.364719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 876394966, states[0] = -94.200316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 885059176, states[0] = 28.216065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893703082, states[0] = -94.364524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 902417198, states[0] = -94.235861, states[40]= 0.000001
Saving checkpoint... 
Iteration: 910802563, states[0] = -94.363719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 919447547, states[0] = -94.272995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 927953633, states[0] = -94.356028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 936535997, states[0] = -94.333218, states[40]= 0.000001
Saving checkpoint... 
Iteration: 944981694, states[0] = -94.353775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 953423814, states[0] = -94.243256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 961958120, states[0] = -94.354513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 965038620, states[0] = 32.999124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973498991, states[0] = -94.312989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982031302, states[0] = 33.659960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990428303, states[0] = -94.247816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 998840539, states[0] = -94.359136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1007400550, states[0] = -94.205416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1015822307, states[0] = -94.359197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024338131, states[0] = -94.048895, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1032942701, states[0] = -94.352763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1041535698, states[0] = -94.329198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1049967710, states[0] = -94.350704, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1058633521, states[0] = -94.353092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1067233326, states[0] = -63.320859, states[40]= 0.000158
Saving checkpoint... 
Iteration: 1075935677, states[0] = -94.351567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1084692440, states[0] = -94.357028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1092862398, states[0] = -94.354715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1098543966, states[0] = -94.330378, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1107314931, states[0] = -93.953727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116020992, states[0] = 33.233436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124638345, states[0] = -94.351250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1133112783, states[0] = 7.537481, states[40]= 0.000230
Saving checkpoint... 
Iteration: 1141759910, states[0] = -94.355988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1150564219, states[0] = -94.335362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1159307516, states[0] = -93.916845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168110759, states[0] = 8.403408, states[40]= 0.000194
Saving checkpoint... 
Iteration: 1176829540, states[0] = -94.352988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1185589274, states[0] = -94.340699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1194170327, states[0] = -23.092989, states[40]= 0.006492
Saving checkpoint... 
Iteration: 1202721010, states[0] = -94.353587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1211346384, states[0] = -94.069233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1220001568, states[0] = 35.162696, states[40]= 2.507423
Saving checkpoint... 
Iteration: 1228563397, states[0] = -94.332242, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1237243216, states[0] = -75.475709, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1245815620, states[0] = -94.350939, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1254554185, states[0] = -94.328298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1263219635, states[0] = -51.694489, states[40]= 0.000848
Saving checkpoint... 
Iteration: 1271726733, states[0] = -94.351118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280452760, states[0] = -94.264940, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1289305572, states[0] = -93.902332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297945860, states[0] = -94.342797, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1300955390, states[0] = -94.342142, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1309352193, states[0] = -94.083292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1318006638, states[0] = 26.531091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323238919, states[0] = -69.406995, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1331906300, states[0] = -94.343709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340561721, states[0] = -94.327564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349325864, states[0] = -93.991002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357943192, states[0] = -94.340727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1366560273, states[0] = -94.326142, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1375125713, states[0] = 1.791975, states[40]= 0.000618
Saving checkpoint... 
Iteration: 1383808049, states[0] = -94.346070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1392810743, states[0] = -94.345652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1401342446, states[0] = -94.049313, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1409957856, states[0] = -94.337966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1418733443, states[0] = -94.345749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1427362760, states[0] = -94.108354, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435987238, states[0] = -94.335295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1444577037, states[0] = -94.328109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1453225475, states[0] = -56.339141, states[40]= 0.000442
Saving checkpoint... 
Iteration: 1461929995, states[0] = -94.337616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1470672305, states[0] = -94.341618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1479397055, states[0] = -94.181594, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1488000535, states[0] = -5.076573, states[40]= 0.006850
Saving checkpoint... 
Iteration: 1496654811, states[0] = -94.339244, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.208117
 - CaMKt in component CaMK (millimolar): 0.009991
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 8.210503
 - nass in component intracellular_ions (millimolar): 8.210683
 - ki in component intracellular_ions (millimolar): 143.316670
 - kss in component intracellular_ions (millimolar): 143.316645
 - cansr in component intracellular_ions (millimolar): 2.137043
 - cajsr in component intracellular_ions (millimolar): 2.139630
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.003881
 - hf in component INa (dimensionless): 0.867432
 - hs in component INa (dimensionless): 0.867434
 - j in component INa (dimensionless): 0.867448
 - hsp in component INa (dimensionless): 0.702613
 - jp in component INa (dimensionless): 0.867455
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.710225
 - hLp in component INaL (dimensionless): 0.492082
 - a in component Ito (dimensionless): 0.000653
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.871101
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.913364
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.959683
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005462
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.124802
 - xs1 in component IKs (dimensionless): 0.168375
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997513
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
17:39:51 (9996): called boinc_finish(0)

</stderr_txt>
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