𝕏

Task 55768647

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_4000-conf_486_1
Workunit 26482472
Created 2 Jul 2024, 14:06:34 UTC
Sent 2 Jul 2024, 21:28:55 UTC
Report deadline 5 Jul 2024, 21:28:55 UTC
Received 4 Jul 2024, 1:26:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241293
Run time 1 hours 47 min 42 sec
CPU time 1 hours 46 min 59 sec
Validate state Valid
Credit 42.48
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_4000-conf_486.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_4000-conf_486_1_r155850374_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_4000-conf_486_1_r155850374_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.845340
     * GNaL_b in INaL: 0.006011
     * Gto_b in Ito: 0.084102
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031442
     * GKs_b in IKs: 0.001964
     * GK1_b in IK1: 0.168007
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.125241
     * GKb_b in IKb: 0.003793
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033308
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8757572, states[0] = -94.438539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17211558, states[0] = -94.371510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26008934, states[0] = 19.824767, states[40]= 0.003895
Saving checkpoint... 
Iteration: 34040191, states[0] = 26.673779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42657972, states[0] = -94.337504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51002686, states[0] = -94.325556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59899574, states[0] = -94.302358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68355212, states[0] = -94.222354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76987224, states[0] = -94.330580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85280289, states[0] = -94.321734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93495204, states[0] = -94.317515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101673982, states[0] = -94.315090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110179473, states[0] = -82.277090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 118867213, states[0] = -94.343401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127274476, states[0] = -94.328561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135798904, states[0] = -94.316768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143922689, states[0] = -94.315278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152609885, states[0] = -94.349363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161118922, states[0] = -94.335881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169734522, states[0] = -94.319383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178296538, states[0] = -94.117835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186598091, states[0] = -94.349420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195136170, states[0] = -94.335770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203837385, states[0] = -94.317911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212715083, states[0] = -94.351593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221395927, states[0] = -94.327409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229716648, states[0] = -94.319987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238124897, states[0] = -16.888669, states[40]= 0.000278
Saving checkpoint... 
Iteration: 246661963, states[0] = -94.351600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255257028, states[0] = -94.331339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263900872, states[0] = -94.316554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272068342, states[0] = 19.657433, states[40]= 0.000002
Saving checkpoint... 
Iteration: 280614164, states[0] = -94.349920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289194553, states[0] = -94.333098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297135614, states[0] = -94.335128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305101852, states[0] = -94.336311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313302077, states[0] = -94.329307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322052550, states[0] = 24.437038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330618083, states[0] = -94.349546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338923790, states[0] = -94.343192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347141344, states[0] = -94.334339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355305639, states[0] = -94.328703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363682059, states[0] = -94.319262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372322131, states[0] = -94.177762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380999296, states[0] = -94.339515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389451855, states[0] = -94.324169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397957345, states[0] = -94.314169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406575402, states[0] = -94.345660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414709241, states[0] = -94.349598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423314077, states[0] = -94.327622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431434755, states[0] = -94.324104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439957213, states[0] = -94.313659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448542472, states[0] = -94.341022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457583642, states[0] = -94.320183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466088454, states[0] = 10.677806, states[40]= 0.000032
Saving checkpoint... 
Iteration: 474557111, states[0] = -94.342781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482588162, states[0] = -94.345866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491195038, states[0] = -94.330671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499802755, states[0] = -94.315377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508161334, states[0] = -57.412946, states[40]= 0.000043
Saving checkpoint... 
Iteration: 516422478, states[0] = -94.297819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525353769, states[0] = -94.325204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534034471, states[0] = 26.458879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542513191, states[0] = -94.334320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550699994, states[0] = -94.348055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559249033, states[0] = -94.328024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567764211, states[0] = -94.315232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576099358, states[0] = 4.599546, states[40]= 0.000103
Saving checkpoint... 
Iteration: 584595660, states[0] = -94.345194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593007276, states[0] = -94.336613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601333855, states[0] = -94.324866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609853267, states[0] = -94.313193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618284377, states[0] = -94.076994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627053392, states[0] = -94.334323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635315890, states[0] = -94.324990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643552421, states[0] = -94.318627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651679855, states[0] = -94.315805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660165331, states[0] = -62.132544, states[40]= 0.000022
Saving checkpoint... 
Iteration: 668629839, states[0] = -94.345925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677136311, states[0] = -94.330520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685813686, states[0] = -94.312926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694460908, states[0] = -94.315967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703167936, states[0] = -94.329053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711372773, states[0] = -94.322399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720217429, states[0] = -93.748071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728706230, states[0] = -94.345829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737009774, states[0] = -94.334761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746010143, states[0] = 20.875195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754493345, states[0] = -94.326645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763266258, states[0] = -94.324987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771836529, states[0] = -94.311498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780411835, states[0] = -94.287244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788783957, states[0] = -94.343244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797242523, states[0] = -94.325348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805777688, states[0] = -94.312098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814077861, states[0] = 15.763123, states[40]= 0.000009
Saving checkpoint... 
Iteration: 822413916, states[0] = -94.288245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830870922, states[0] = -94.339445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839774252, states[0] = -94.311746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848122206, states[0] = -14.065245, states[40]= 0.000282
Saving checkpoint... 
Iteration: 856429976, states[0] = -94.298375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864984692, states[0] = -94.334253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873238621, states[0] = -94.324555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881830950, states[0] = -94.310256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890320255, states[0] = -94.167531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898639187, states[0] = -94.343424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906716816, states[0] = -94.343524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915620707, states[0] = -94.313813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924119614, states[0] = -11.391741, states[40]= 0.000295
Saving checkpoint... 
Iteration: 932075511, states[0] = 16.788110, states[40]= 0.000006
Saving checkpoint... 
Iteration: 940642587, states[0] = -94.343001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948889519, states[0] = -94.337241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957923238, states[0] = -94.307863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966438919, states[0] = -94.302129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974924775, states[0] = -94.335442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983641353, states[0] = -94.312553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992069583, states[0] = 19.190956, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1000579333, states[0] = -94.338832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009253544, states[0] = -94.322412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017702468, states[0] = -94.310916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026235678, states[0] = -93.858836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034273660, states[0] = -94.034986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042955077, states[0] = -94.333338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051371995, states[0] = -94.318294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060185649, states[0] = -91.184657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068611826, states[0] = -94.340307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076817609, states[0] = -94.338566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085193761, states[0] = -94.323503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093371450, states[0] = -94.317796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101883386, states[0] = -94.306727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109792017, states[0] = -94.308147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118183399, states[0] = -89.090925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126550287, states[0] = -94.333960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135218568, states[0] = -94.322042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144010929, states[0] = 21.324197, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1152370479, states[0] = -94.244018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160606684, states[0] = -94.338908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169076176, states[0] = -94.326842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177409138, states[0] = -94.315726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186154857, states[0] = -49.832100, states[40]= 0.000110
Saving checkpoint... 
Iteration: 1194950046, states[0] = -94.331702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203387381, states[0] = -94.316011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211650566, states[0] = -94.309591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220347244, states[0] = -94.211999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228382702, states[0] = -94.256468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236910480, states[0] = -94.332868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245662985, states[0] = -94.308925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253944937, states[0] = -94.303941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262413928, states[0] = -94.282902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270798755, states[0] = -94.336894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279357338, states[0] = -94.315939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288222713, states[0] = -93.776168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296995953, states[0] = -94.328536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305285659, states[0] = -94.317785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314023266, states[0] = 25.324486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322659488, states[0] = -94.338670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331428877, states[0] = -94.313323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339692325, states[0] = -94.307194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348454752, states[0] = -94.305335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356543176, states[0] = -94.330119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365302643, states[0] = -94.316528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373694965, states[0] = -94.306730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382187316, states[0] = -92.130214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390780588, states[0] = -94.336052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399255051, states[0] = -94.317623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407686129, states[0] = -94.306491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416420434, states[0] = -94.285531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424778399, states[0] = -94.335711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433072141, states[0] = -94.323796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441650311, states[0] = -94.306799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449877474, states[0] = -94.302589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458324626, states[0] = -94.169506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466970441, states[0] = -94.327543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475401260, states[0] = -94.312323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483953247, states[0] = -94.301023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492450445, states[0] = -94.301593, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.176133
 - CaMKt in component CaMK (millimolar): 0.002338
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.143007
 - nass in component intracellular_ions (millimolar): 7.143144
 - ki in component intracellular_ions (millimolar): 144.530290
 - kss in component intracellular_ions (millimolar): 144.530275
 - cansr in component intracellular_ions (millimolar): 2.421368
 - cajsr in component intracellular_ions (millimolar): 2.421827
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003894
 - hf in component INa (dimensionless): 0.866826
 - hs in component INa (dimensionless): 0.866826
 - j in component INa (dimensionless): 0.866830
 - hsp in component INa (dimensionless): 0.701502
 - jp in component INa (dimensionless): 0.866831
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709645
 - hLp in component INaL (dimensionless): 0.515984
 - a in component Ito (dimensionless): 0.000655
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.999852
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999852
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996731
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005335
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.006637
 - xs1 in component IKs (dimensionless): 0.039855
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997521
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:41:28 (38435): called boinc_finish(0)

</stderr_txt>
]]>


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