𝕏

Task 55767560

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585_1
Workunit 26481939
Created 2 Jul 2024, 14:05:57 UTC
Sent 2 Jul 2024, 21:21:42 UTC
Report deadline 5 Jul 2024, 21:21:42 UTC
Received 3 Jul 2024, 6:16:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213867
Run time 1 hours 11 min 55 sec
CPU time 1 hours 10 min 5 sec
Validate state Valid
Credit 45.88
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.74 MB
Peak swap size 6.23 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.11</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585_1_r1558025968_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585_1_r1558025968_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.110237
     * GNaL_b in INaL: 0.005796
     * Gto_b in Ito: 0.087357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032291
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.159388
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.581742
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037359
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 22610136, states[0] = -2.231122, states[40]= 0.000072
Saving checkpoint... 
Iteration: 45593482, states[0] = -94.263882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68119611, states[0] = -94.271920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90571146, states[0] = -94.276710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113489335, states[0] = -94.272036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136288388, states[0] = -94.261573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158606576, states[0] = -94.270303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181301509, states[0] = -94.262780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204231861, states[0] = -93.772173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227041534, states[0] = -94.282340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249514252, states[0] = -94.277115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272379419, states[0] = -94.281226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294758976, states[0] = -94.286426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316946448, states[0] = -94.252987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339480391, states[0] = -94.266488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362391309, states[0] = -94.279114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385045665, states[0] = -94.271005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407197335, states[0] = -94.286324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429781731, states[0] = -94.283191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452718150, states[0] = -94.262201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475330110, states[0] = -94.257558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497528912, states[0] = -94.269858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520186523, states[0] = -94.262325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543073664, states[0] = 16.506372, states[40]= 0.000006
Saving checkpoint... 
Iteration: 564634604, states[0] = -94.283672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586892269, states[0] = -94.210928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609576247, states[0] = -94.279968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632117896, states[0] = -94.282039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654504050, states[0] = -94.267820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677409592, states[0] = -94.272702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700175525, states[0] = -94.259649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722631961, states[0] = -94.261139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744918048, states[0] = -94.271092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767954241, states[0] = -94.248323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790491409, states[0] = -94.246807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812537381, states[0] = -94.263950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835104415, states[0] = -94.260412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858087581, states[0] = 9.783757, states[40]= 0.000038
Saving checkpoint... 
Iteration: 880704148, states[0] = -93.561059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903349284, states[0] = -94.153805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926242552, states[0] = -94.276064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949106013, states[0] = -94.258358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971441845, states[0] = -94.265937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994024627, states[0] = -94.261409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016835067, states[0] = -94.247938, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585_1_r1558025968_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585_1_r1558025968_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.110237
     * GNaL_b in INaL: 0.005796
     * Gto_b in Ito: 0.087357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032291
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.159388
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.581742
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037359
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1016835067
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.247938 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1040337913, states[0] = -94.269979, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585_1_r1558025968_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585_1_r1558025968_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.110237
     * GNaL_b in INaL: 0.005796
     * Gto_b in Ito: 0.087357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032291
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.159388
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.581742
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037359
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1040337913
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.269979 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1063860419, states[0] = -94.166914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087284859, states[0] = -94.248535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110229736, states[0] = -93.743003, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585_1_r1558025968_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585_1_r1558025968_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.110237
     * GNaL_b in INaL: 0.005796
     * Gto_b in Ito: 0.087357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032291
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.159388
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.581742
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037359
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1110229736
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.743003 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1133515633, states[0] = -94.259416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156743551, states[0] = -93.823959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179896396, states[0] = -94.264619, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585_1_r1558025968_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585_1_r1558025968_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.110237
     * GNaL_b in INaL: 0.005796
     * Gto_b in Ito: 0.087357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032291
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.159388
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.581742
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037359
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1179896396
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.264619 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1203596543, states[0] = -94.271096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226870110, states[0] = -94.243051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250059016, states[0] = -94.267083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273314203, states[0] = -94.244203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295451573, states[0] = -94.259793, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585_1_r1558025968_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_585_1_r1558025968_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.110237
     * GNaL_b in INaL: 0.005796
     * Gto_b in Ito: 0.087357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032291
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.159388
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.581742
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037359
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1295451573
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.259793 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1320995639, states[0] = -94.257137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347243918, states[0] = -93.822553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372125390, states[0] = -94.250103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398522417, states[0] = -94.258910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423651325, states[0] = -51.197620, states[40]= 0.000085
Saving checkpoint... 
Iteration: 1445738257, states[0] = -94.244081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468186464, states[0] = -94.245796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489676252, states[0] = -84.677090, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.110129
 - CaMKt in component CaMK (millimolar): 0.003674
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.218199
 - nass in component intracellular_ions (millimolar): 7.218339
 - ki in component intracellular_ions (millimolar): 144.405472
 - kss in component intracellular_ions (millimolar): 144.405454
 - cansr in component intracellular_ions (millimolar): 2.467803
 - cajsr in component intracellular_ions (millimolar): 2.468479
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003920
 - hf in component INa (dimensionless): 0.865569
 - hs in component INa (dimensionless): 0.865570
 - j in component INa (dimensionless): 0.865577
 - hsp in component INa (dimensionless): 0.699231
 - jp in component INa (dimensionless): 0.865581
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707873
 - hLp in component INaL (dimensionless): 0.511568
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999850
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999850
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991228
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005320
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.024851
 - xs1 in component IKs (dimensionless): 0.068708
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997537
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:00:33 (8480): called boinc_finish(0)

</stderr_txt>
]]>


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