𝕏

Task 55767557

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_485_0
Workunit 26481938
Created 2 Jul 2024, 14:05:57 UTC
Sent 2 Jul 2024, 21:22:34 UTC
Report deadline 5 Jul 2024, 21:22:34 UTC
Received 3 Jul 2024, 6:59:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 16 min 49 sec
CPU time 2 hours 12 min 7 sec
Validate state Valid
Credit 43.65
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.45 MB
Peak swap size 2.35 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_485.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_485_0_r1010336351_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_485_0_r1010336351_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.553140
     * GNaL_b in INaL: 0.006196
     * Gto_b in Ito: 0.086094
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031336
     * GKs_b in IKs: 0.001967
     * GK1_b in IK1: 0.166142
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.137937
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029777
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11168480, states[0] = -94.404570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22195415, states[0] = -94.339916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33397175, states[0] = -94.271177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44611048, states[0] = -94.316158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55812981, states[0] = -94.146532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67013330, states[0] = -94.325440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78264329, states[0] = -94.002617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89495446, states[0] = -94.333631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100692055, states[0] = -93.344834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111937220, states[0] = -94.341250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123154837, states[0] = -51.375522, states[40]= 0.000114
Saving checkpoint... 
Iteration: 134359857, states[0] = -94.347585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145467307, states[0] = -94.323913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156647375, states[0] = -94.354932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167825651, states[0] = -94.329200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178915876, states[0] = -94.302892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190205192, states[0] = -94.333855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201434597, states[0] = -94.314595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212679080, states[0] = -94.334835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223911137, states[0] = -94.299462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235101310, states[0] = -94.337867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246327444, states[0] = -94.196735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257493786, states[0] = -94.342438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268739198, states[0] = -93.894440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279957212, states[0] = -94.343831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291198884, states[0] = -93.604916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302412909, states[0] = -94.345597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313465415, states[0] = -94.323574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324699999, states[0] = -94.353630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335764674, states[0] = -94.329756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346990921, states[0] = -94.335534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358214478, states[0] = -94.331248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369423079, states[0] = -94.305289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380623934, states[0] = -94.334520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391814959, states[0] = -94.168491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403018771, states[0] = -94.338803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414270502, states[0] = -94.037118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425498404, states[0] = -94.339356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436704535, states[0] = -93.659447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447910038, states[0] = -94.343187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459134334, states[0] = -28.512998, states[40]= 0.000580
Saving checkpoint... 
Iteration: 470334329, states[0] = -94.346366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481473712, states[0] = -94.320376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492523374, states[0] = -94.340609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503713232, states[0] = -94.328724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514921576, states[0] = -94.301750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526141061, states[0] = -94.331226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537320531, states[0] = -94.177885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548533733, states[0] = -94.335539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559734282, states[0] = -93.861171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570927444, states[0] = -94.340177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582162634, states[0] = -60.938898, states[40]= 0.000033
Saving checkpoint... 
Iteration: 593383234, states[0] = -94.341901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604571435, states[0] = 17.927492, states[40]= 0.000005
Saving checkpoint... 
Iteration: 615785382, states[0] = -94.345895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626981194, states[0] = -94.317580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638030476, states[0] = -94.339321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649224209, states[0] = -94.325725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660358786, states[0] = -94.239767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668935696, states[0] = -94.318180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680107489, states[0] = -94.346440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691263923, states[0] = -94.323502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702510691, states[0] = -94.334284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713732777, states[0] = -94.324267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724962587, states[0] = -94.319184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736138929, states[0] = -94.327610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747333623, states[0] = -94.199384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758566927, states[0] = -94.330327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769797138, states[0] = -94.117527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781042769, states[0] = -94.331020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792263472, states[0] = -94.002286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803466600, states[0] = -94.334191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814660870, states[0] = -58.845439, states[40]= 0.000044
Saving checkpoint... 
Iteration: 825713081, states[0] = -94.344539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836762808, states[0] = -94.320970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847949318, states[0] = -94.311226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859198008, states[0] = -94.323033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870429126, states[0] = -94.300139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881615532, states[0] = -94.326022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892831406, states[0] = -94.192786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904069038, states[0] = -94.327659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915285326, states[0] = -94.079878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926436595, states[0] = -94.333457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937655202, states[0] = -52.213544, states[40]= 0.000102
Saving checkpoint... 
Iteration: 948728923, states[0] = -94.341966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959957300, states[0] = -94.312386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971174149, states[0] = -94.342518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982276270, states[0] = -94.317902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993534796, states[0] = -94.333770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004762779, states[0] = -94.317997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015813902, states[0] = -94.154989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027055204, states[0] = -94.326107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038306030, states[0] = -94.135979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049552593, states[0] = -94.325824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060784266, states[0] = -94.073867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071988975, states[0] = -94.328374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083136464, states[0] = -30.772089, states[40]= 0.000586
Saving checkpoint... 
Iteration: 1094335166, states[0] = -94.335301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105563980, states[0] = 20.709340, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1116809977, states[0] = -94.336028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128013414, states[0] = 22.249950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139037424, states[0] = -94.331621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150277261, states[0] = -94.314892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161504850, states[0] = -94.324812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172737696, states[0] = -94.315953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183962964, states[0] = -94.311209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195182925, states[0] = -94.317682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206404889, states[0] = -94.277613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217658696, states[0] = -94.318272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228845679, states[0] = -94.210853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240032948, states[0] = -94.323356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251137634, states[0] = -32.031176, states[40]= 0.000573
Saving checkpoint... 
Iteration: 1262394454, states[0] = -94.329552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273625274, states[0] = -18.971932, states[40]= 0.000351
Saving checkpoint... 
Iteration: 1284850864, states[0] = -94.331222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295945603, states[0] = -94.306788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307113128, states[0] = -94.335622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318371927, states[0] = -94.308683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329419343, states[0] = -94.285872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340563019, states[0] = -94.320212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351777138, states[0] = -94.044599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363004548, states[0] = -94.322506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374237373, states[0] = -93.864197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385473086, states[0] = -94.323595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396705886, states[0] = -93.652811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407939896, states[0] = -94.324787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419184859, states[0] = -91.639747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430425695, states[0] = -94.325073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441628281, states[0] = -22.132708, states[40]= 0.000417
Saving checkpoint... 
Iteration: 1452643561, states[0] = -94.333885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463860949, states[0] = -94.306467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475075335, states[0] = -94.330261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486305183, states[0] = -94.307961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497476466, states[0] = -94.310675, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.177558
 - CaMKt in component CaMK (millimolar): 0.003711
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 7.251248
 - nass in component intracellular_ions (millimolar): 7.251390
 - ki in component intracellular_ions (millimolar): 144.366698
 - kss in component intracellular_ions (millimolar): 144.366680
 - cansr in component intracellular_ions (millimolar): 2.485077
 - cajsr in component intracellular_ions (millimolar): 2.485791
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003893
 - hf in component INa (dimensionless): 0.866853
 - hs in component INa (dimensionless): 0.866854
 - j in component INa (dimensionless): 0.866861
 - hsp in component INa (dimensionless): 0.701555
 - jp in component INa (dimensionless): 0.866864
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709727
 - hLp in component INaL (dimensionless): 0.513741
 - a in component Ito (dimensionless): 0.000655
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.999852
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999852
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990997
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005447
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.025003
 - xs1 in component IKs (dimensionless): 0.069854
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997521
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:54:31 (18814): called boinc_finish(0)

</stderr_txt>
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