𝕏

Task 55767425

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685_0
Workunit 26481872
Created 2 Jul 2024, 14:05:52 UTC
Sent 2 Jul 2024, 21:19:17 UTC
Report deadline 5 Jul 2024, 21:19:17 UTC
Received 3 Jul 2024, 6:00:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213867
Run time 1 hours 11 min 35 sec
CPU time 1 hours 10 min 4 sec
Validate state Valid
Credit 45.87
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.75 MB
Peak swap size 6.23 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.11</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685_0_r1882396795_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685_0_r1882396795_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.866644
     * GNaL_b in INaL: 0.005554
     * Gto_b in Ito: 0.081396
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031428
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.161452
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.134811
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035733
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 22524106, states[0] = 31.047253, states[40]= 0.000574
Saving checkpoint... 
Iteration: 44764200, states[0] = -94.019968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67497381, states[0] = -94.006593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90334717, states[0] = -93.821357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113219659, states[0] = -94.031245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135654750, states[0] = -94.028229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158847059, states[0] = -94.009778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181829470, states[0] = -93.809009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204370622, states[0] = -93.885061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227083400, states[0] = -94.019143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250025650, states[0] = -94.022384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272811929, states[0] = -94.010609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295497320, states[0] = -94.004394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318476772, states[0] = -93.983642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341310446, states[0] = -94.029971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363764969, states[0] = -94.030498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386006769, states[0] = -93.997339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409165456, states[0] = -94.015881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431973025, states[0] = -94.004692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454215523, states[0] = -94.013702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476688126, states[0] = -94.014733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499823082, states[0] = -93.793026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522560913, states[0] = -94.013582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544702400, states[0] = -79.521649, states[40]= 0.000002
Saving checkpoint... 
Iteration: 567180799, states[0] = -57.776638, states[40]= 0.000066
Saving checkpoint... 
Iteration: 590240589, states[0] = -94.029752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612013688, states[0] = 31.615958, states[40]= 0.016336
Saving checkpoint... 
Iteration: 634458856, states[0] = -94.004480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657400347, states[0] = -93.922144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680163490, states[0] = -94.026966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702589785, states[0] = -94.018723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725381476, states[0] = -94.026714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748599802, states[0] = 3.809776, states[40]= 0.003276
Saving checkpoint... 
Iteration: 771187637, states[0] = -63.551949, states[40]= 0.000026
Saving checkpoint... 
Iteration: 793693169, states[0] = -68.730179, states[40]= 0.000011
Saving checkpoint... 
Iteration: 816641156, states[0] = -94.024824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839559121, states[0] = -94.019032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861708812, states[0] = -94.028375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884385773, states[0] = -94.026053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907377962, states[0] = -94.006243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930371736, states[0] = -93.884356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952986825, states[0] = -93.986726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975868819, states[0] = -94.026340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998943209, states[0] = -94.003802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021393693, states[0] = -94.005345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043800327, states[0] = -94.008556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066926464, states[0] = -93.946618, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685_0_r1882396795_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685_0_r1882396795_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.866644
     * GNaL_b in INaL: 0.005554
     * Gto_b in Ito: 0.081396
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031428
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.161452
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.134811
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035733
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1066926464
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.946618 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1090593549, states[0] = 6.944448, states[40]= 0.002793


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685_0_r1882396795_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685_0_r1882396795_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.866644
     * GNaL_b in INaL: 0.005554
     * Gto_b in Ito: 0.081396
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031428
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.161452
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.134811
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035733
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1090593549
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 6.944448 (After loading)
 - states[40]: 0.002793 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1114100426, states[0] = -94.016365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137378014, states[0] = -93.892696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160569962, states[0] = -94.017532, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685_0_r1882396795_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685_0_r1882396795_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.866644
     * GNaL_b in INaL: 0.005554
     * Gto_b in Ito: 0.081396
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031428
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.161452
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.134811
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035733
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1160569962
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.017532 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1183476290, states[0] = -94.002178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206454836, states[0] = -93.967725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229109383, states[0] = -94.019988, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685_0_r1882396795_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685_0_r1882396795_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.866644
     * GNaL_b in INaL: 0.005554
     * Gto_b in Ito: 0.081396
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031428
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.161452
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.134811
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035733
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1229109383
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.019988 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1253266280, states[0] = -94.027641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276522756, states[0] = 31.474265, states[40]= 0.000771
Saving checkpoint... 
Iteration: 1299596902, states[0] = -94.017960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322764826, states[0] = -94.008991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344660840, states[0] = -94.024663, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685_0_r1882396795_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_685_0_r1882396795_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.866644
     * GNaL_b in INaL: 0.005554
     * Gto_b in Ito: 0.081396
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031428
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.161452
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.134811
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035733
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1344660840
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.024663 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1370026063, states[0] = -94.001193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396054910, states[0] = -94.017430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421234619, states[0] = -94.027039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447783693, states[0] = -93.673197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473069259, states[0] = 17.291762, states[40]= 0.001007
Saving checkpoint... 
Iteration: 1495098548, states[0] = -94.015224, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.876402
 - CaMKt in component CaMK (millimolar): 0.003110
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 6.751904
 - nass in component intracellular_ions (millimolar): 6.752024
 - ki in component intracellular_ions (millimolar): 145.100803
 - kss in component intracellular_ions (millimolar): 145.100792
 - cansr in component intracellular_ions (millimolar): 1.832063
 - cajsr in component intracellular_ions (millimolar): 1.831862
 - cai in component intracellular_ions (millimolar): 0.000103
 - m in component INa (dimensionless): 0.004013
 - hf in component INa (dimensionless): 0.861037
 - hs in component INa (dimensionless): 0.861038
 - j in component INa (dimensionless): 0.861046
 - hsp in component INa (dimensionless): 0.691093
 - jp in component INa (dimensionless): 0.861050
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.701376
 - hLp in component INaL (dimensionless): 0.503130
 - a in component Ito (dimensionless): 0.000668
 - iF in component Ito (dimensionless): 0.999844
 - iS in component Ito (dimensionless): 0.968736
 - ap in component Ito (dimensionless): 0.000340
 - iFp in component Ito (dimensionless): 0.999844
 - iSp in component Ito (dimensionless): 0.984145
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990149
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004995
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.030132
 - xs1 in component IKs (dimensionless): 0.072684
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997594
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:58:03 (16876): called boinc_finish(0)

</stderr_txt>
]]>


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