𝕏

Task 55767415

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785_0
Workunit 26481867
Created 2 Jul 2024, 14:05:52 UTC
Sent 2 Jul 2024, 21:19:17 UTC
Report deadline 5 Jul 2024, 21:19:17 UTC
Received 3 Jul 2024, 6:00:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213867
Run time 1 hours 11 min 27 sec
CPU time 1 hours 9 min 53 sec
Validate state Valid
Credit 47.30
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.74 MB
Peak swap size 6.24 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.11</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785_0_r1071146970_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785_0_r1071146970_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.170794
     * GNaL_b in INaL: 0.005710
     * Gto_b in Ito: 0.088096
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032228
     * GKs_b in IKs: 0.001948
     * GK1_b in IK1: 0.160960
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.131300
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033949
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 22040575, states[0] = 26.688668, states[40]= 0.000312
Saving checkpoint... 
Iteration: 44455562, states[0] = -94.083465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67613599, states[0] = -94.129174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90569500, states[0] = -94.124122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113242212, states[0] = -93.640632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136104567, states[0] = -0.924715, states[40]= 0.003334
Saving checkpoint... 
Iteration: 159153575, states[0] = -41.338109, states[40]= 0.000615
Saving checkpoint... 
Iteration: 182020332, states[0] = 31.365253, states[40]= 0.001700
Saving checkpoint... 
Iteration: 204541643, states[0] = -94.119109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227312330, states[0] = -93.896340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250344670, states[0] = -93.965053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272928996, states[0] = -94.128784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295547742, states[0] = -94.120158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318678190, states[0] = -94.134629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340922255, states[0] = -94.128792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363567489, states[0] = -94.123879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386315344, states[0] = -93.903015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409321972, states[0] = -93.918447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431956844, states[0] = -94.126611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454413025, states[0] = -94.052541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477258462, states[0] = -93.714789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500298533, states[0] = -93.857849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522734279, states[0] = -94.134275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544903854, states[0] = -94.128690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567865025, states[0] = -94.130356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590348982, states[0] = -93.970955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612281493, states[0] = -93.803381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634950543, states[0] = -94.125940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657692275, states[0] = -94.133336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680340540, states[0] = -93.955385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702745563, states[0] = -94.133305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725699231, states[0] = -94.133128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748589340, states[0] = -94.125518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771261323, states[0] = -93.725511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793990022, states[0] = -94.123132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817236154, states[0] = -93.607335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839930972, states[0] = -94.125924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862228277, states[0] = -93.563683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885224185, states[0] = -93.535646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908396203, states[0] = -94.033795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931019860, states[0] = 31.401060, states[40]= 0.001991
Saving checkpoint... 
Iteration: 953861657, states[0] = -94.128617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977104733, states[0] = -1.040973, states[40]= 0.003332
Saving checkpoint... 
Iteration: 1000021831, states[0] = 31.220184, states[40]= 0.001038
Saving checkpoint... 
Iteration: 1022483391, states[0] = -94.095497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045292296, states[0] = -93.836505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068384141, states[0] = -94.019341, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785_0_r1071146970_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785_0_r1071146970_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.170794
     * GNaL_b in INaL: 0.005710
     * Gto_b in Ito: 0.088096
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032228
     * GKs_b in IKs: 0.001948
     * GK1_b in IK1: 0.160960
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.131300
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033949
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1068384141
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.019341 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1091956331, states[0] = -94.123413, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785_0_r1071146970_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785_0_r1071146970_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.170794
     * GNaL_b in INaL: 0.005710
     * Gto_b in Ito: 0.088096
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032228
     * GKs_b in IKs: 0.001948
     * GK1_b in IK1: 0.160960
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.131300
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033949
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1091956331
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.123413 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1115532934, states[0] = -94.112481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138934988, states[0] = -94.124262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162236872, states[0] = -93.609307, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785_0_r1071146970_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785_0_r1071146970_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.170794
     * GNaL_b in INaL: 0.005710
     * Gto_b in Ito: 0.088096
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032228
     * GKs_b in IKs: 0.001948
     * GK1_b in IK1: 0.160960
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.131300
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033949
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1162236872
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.609307 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1185677439, states[0] = -94.130375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209203415, states[0] = -91.014453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232248273, states[0] = -93.665024, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785_0_r1071146970_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785_0_r1071146970_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.170794
     * GNaL_b in INaL: 0.005710
     * Gto_b in Ito: 0.088096
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032228
     * GKs_b in IKs: 0.001948
     * GK1_b in IK1: 0.160960
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.131300
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033949
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1232248273
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.665024 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1255976045, states[0] = -94.121599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279169443, states[0] = -55.040273, states[40]= 0.000091
Saving checkpoint... 
Iteration: 1302426699, states[0] = -94.059928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325285239, states[0] = -93.812514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347426099, states[0] = -94.059233, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785_0_r1071146970_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_785_0_r1071146970_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.170794
     * GNaL_b in INaL: 0.005710
     * Gto_b in Ito: 0.088096
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032228
     * GKs_b in IKs: 0.001948
     * GK1_b in IK1: 0.160960
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.131300
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033949
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1347426099
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.059233 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1372919545, states[0] = -94.123885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399715347, states[0] = -94.130000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424813436, states[0] = -94.128186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451279975, states[0] = -93.793927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476286345, states[0] = -93.815415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498440057, states[0] = -94.068834, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.995102
 - CaMKt in component CaMK (millimolar): 0.005737
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 6.840261
 - nass in component intracellular_ions (millimolar): 6.840379
 - ki in component intracellular_ions (millimolar): 144.997157
 - kss in component intracellular_ions (millimolar): 144.997143
 - cansr in component intracellular_ions (millimolar): 1.846533
 - cajsr in component intracellular_ions (millimolar): 1.845685
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003965
 - hf in component INa (dimensionless): 0.863355
 - hs in component INa (dimensionless): 0.863357
 - j in component INa (dimensionless): 0.863369
 - hsp in component INa (dimensionless): 0.695247
 - jp in component INa (dimensionless): 0.863376
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.704497
 - hLp in component INaL (dimensionless): 0.492256
 - a in component Ito (dimensionless): 0.000663
 - iF in component Ito (dimensionless): 0.999847
 - iS in component Ito (dimensionless): 0.886771
 - ap in component Ito (dimensionless): 0.000338
 - iFp in component Ito (dimensionless): 0.999847
 - iSp in component Ito (dimensionless): 0.926334
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.971552
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004554
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.110063
 - xs1 in component IKs (dimensionless): 0.135010
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997565
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:57:53 (15364): called boinc_finish(0)

</stderr_txt>
]]>