𝕏

Task 55764900

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_6000-conf_782_0
Workunit 26480610
Created 2 Jul 2024, 14:04:28 UTC
Sent 2 Jul 2024, 21:03:27 UTC
Report deadline 5 Jul 2024, 21:03:27 UTC
Received 3 Jul 2024, 11:09:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230398
Run time 2 hours 6 min 36 sec
CPU time 2 hours 5 min 11 sec
Validate state Valid
Credit 43.88
Device peak FLOPS 3.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.74 MB
Peak swap size 4.10 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_6000-conf_782.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_6000-conf_782_0_r687880747_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_6000-conf_782_0_r687880747_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.791519
     * GNaL_b in INaL: 0.005653
     * Gto_b in Ito: 0.086683
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031959
     * GKs_b in IKs: 0.001904
     * GK1_b in IK1: 0.163809
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.567848
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036907
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12202303, states[0] = -93.739896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24307832, states[0] = -94.075965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36535524, states[0] = -94.245352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48726430, states[0] = -94.247515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60908878, states[0] = -94.240534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73037993, states[0] = -94.237056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85226522, states[0] = -94.232773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97410128, states[0] = -94.229819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109588407, states[0] = -94.227652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121803499, states[0] = -94.225249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133997400, states[0] = -94.223602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146219822, states[0] = -94.221902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158404541, states[0] = -94.220813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170591593, states[0] = -94.219831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182694072, states[0] = -94.219447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194842072, states[0] = -94.218795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207092447, states[0] = 9.151050, states[40]= 0.000041
Saving checkpoint... 
Iteration: 219243090, states[0] = -93.796164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231493252, states[0] = -94.239767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243667962, states[0] = -94.260396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255882210, states[0] = -94.255127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268201214, states[0] = -94.242848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280384294, states[0] = -94.237314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292523217, states[0] = -94.233834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304661886, states[0] = -94.230881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316762812, states[0] = -94.228986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328885768, states[0] = -94.226964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341041093, states[0] = -94.224793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353146362, states[0] = -94.223484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365255871, states[0] = -94.222269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377390540, states[0] = -94.220968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389547307, states[0] = -94.219676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401583791, states[0] = -94.219329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413697520, states[0] = -94.218512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426031756, states[0] = 26.334290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438062019, states[0] = 22.148260, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450106341, states[0] = 0.841218, states[40]= 0.000163
Saving checkpoint... 
Iteration: 462206513, states[0] = -93.551714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474358073, states[0] = -94.139733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486382564, states[0] = -94.169930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498395084, states[0] = -94.182370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510486400, states[0] = -94.235584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522626536, states[0] = -94.257258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534669171, states[0] = -94.258256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546724141, states[0] = -94.257948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558776212, states[0] = -94.256648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570964387, states[0] = -94.249382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583061207, states[0] = -94.245435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595116168, states[0] = -94.243279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607137067, states[0] = -94.242429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619189536, states[0] = -94.240513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631273826, states[0] = -94.237714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643394885, states[0] = -94.234185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655464440, states[0] = -94.232336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667548280, states[0] = -94.230315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679620630, states[0] = -94.228709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691725980, states[0] = -94.226634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703835041, states[0] = -94.224734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716047058, states[0] = -94.221719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728173172, states[0] = -94.220192, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_6000-conf_782.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_6000-conf_782_0_r687880747_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_6000-conf_782_0_r687880747_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.791519
     * GNaL_b in INaL: 0.005653
     * Gto_b in Ito: 0.086683
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031959
     * GKs_b in IKs: 0.001904
     * GK1_b in IK1: 0.163809
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.567848
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036907
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 728173172
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.220192 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 740239008, states[0] = -94.219425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752258065, states[0] = -94.219143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763894801, states[0] = -94.223355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775927903, states[0] = -94.222788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787987140, states[0] = -94.221893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799933804, states[0] = -94.222512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811944009, states[0] = -94.222276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823932525, states[0] = -94.222337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836026951, states[0] = -94.221000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848089924, states[0] = -94.220146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860131162, states[0] = -94.219583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872213058, states[0] = -94.218620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884180922, states[0] = -94.218854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896244380, states[0] = -94.218116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908221404, states[0] = -94.218246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920329906, states[0] = -94.217126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932397408, states[0] = -94.216451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944426349, states[0] = -94.216120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956433031, states[0] = -94.215971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968531380, states[0] = -94.215135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980594529, states[0] = -94.214603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992669135, states[0] = -94.214029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004679716, states[0] = -94.213867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016722135, states[0] = -94.213519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028706308, states[0] = -94.213515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040761791, states[0] = -94.213100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052845933, states[0] = -94.212555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064875533, states[0] = -94.212310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076987098, states[0] = -94.211694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089106031, states[0] = 1.055760, states[40]= 0.000158
Saving checkpoint... 
Iteration: 1101149870, states[0] = -42.662751, states[40]= 0.000212
Saving checkpoint... 
Iteration: 1113192947, states[0] = -93.022413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125216913, states[0] = -93.625073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137213151, states[0] = -93.598098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149268874, states[0] = -93.911262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161317706, states[0] = -94.061285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173356732, states[0] = -94.132176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185350613, states[0] = -94.122954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197355821, states[0] = -94.130663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209107626, states[0] = -0.044267, states[40]= 0.000180
Saving checkpoint... 
Iteration: 1219820031, states[0] = -94.220817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230766231, states[0] = -94.251541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242838568, states[0] = -94.249040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254948973, states[0] = -94.244522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266948821, states[0] = -94.244433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279030690, states[0] = -94.241035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291089910, states[0] = -94.238661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302996761, states[0] = -94.242195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314821574, states[0] = -94.249089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327019601, states[0] = -94.241089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339182860, states[0] = -94.234956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351364290, states[0] = -94.229317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363628136, states[0] = -94.223060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375797972, states[0] = -94.219917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388038124, states[0] = -94.216423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400352372, states[0] = -94.213068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412650833, states[0] = -94.210763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424912738, states[0] = -94.209232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437067368, states[0] = 20.368135, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1449213332, states[0] = -93.596809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461494832, states[0] = -94.230628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473758214, states[0] = -94.249804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485975276, states[0] = -94.241594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498189555, states[0] = -94.233451, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.084210
 - CaMKt in component CaMK (millimolar): 0.001369
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.071369
 - nass in component intracellular_ions (millimolar): 7.071504
 - ki in component intracellular_ions (millimolar): 144.641658
 - kss in component intracellular_ions (millimolar): 144.641646
 - cansr in component intracellular_ions (millimolar): 2.382193
 - cajsr in component intracellular_ions (millimolar): 2.382482
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003930
 - hf in component INa (dimensionless): 0.865072
 - hs in component INa (dimensionless): 0.865072
 - j in component INa (dimensionless): 0.865073
 - hsp in component INa (dimensionless): 0.698327
 - jp in component INa (dimensionless): 0.865074
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707079
 - hLp in component INaL (dimensionless): 0.513336
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999850
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999850
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999560
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005301
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000469
 - xs1 in component IKs (dimensionless): 0.014139
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997544
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:09:16 (65948): called boinc_finish(0)

</stderr_txt>
]]>


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