𝕏

Task 55763782

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_781_0
Workunit 26480051
Created 2 Jul 2024, 14:03:52 UTC
Sent 2 Jul 2024, 20:58:50 UTC
Report deadline 5 Jul 2024, 20:58:50 UTC
Received 4 Jul 2024, 5:16:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 4 min 43 sec
CPU time 1 hours 29 min 53 sec
Validate state Valid
Credit 43.06
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_781.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_781_0_r374767881_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_781_0_r374767881_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.996588
     * GNaL_b in INaL: 0.006228
     * Gto_b in Ito: 0.083104
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031761
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.164617
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.386597
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028896
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7466923, states[0] = -94.377546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15660477, states[0] = -94.336283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23204637, states[0] = -94.311804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31980456, states[0] = -94.276292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39245336, states[0] = -93.868616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47367491, states[0] = -94.286679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55481409, states[0] = -94.263997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63077294, states[0] = 15.753636, states[40]= 0.000009
Saving checkpoint... 
Iteration: 71242499, states[0] = -94.299993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79384245, states[0] = -94.275727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86450097, states[0] = -94.296055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93821174, states[0] = -94.304505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102237200, states[0] = -93.836871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110099962, states[0] = -94.311303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118697418, states[0] = -93.543365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126394516, states[0] = -94.245818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135147601, states[0] = -44.584114, states[40]= 0.000215
Saving checkpoint... 
Iteration: 143892048, states[0] = -94.287623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150798251, states[0] = -94.313521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160253068, states[0] = -94.293286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167923608, states[0] = -94.287646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176252135, states[0] = -94.316136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185643890, states[0] = -94.298176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193681040, states[0] = -89.504217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202977230, states[0] = -94.295931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212392004, states[0] = -94.310029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220304362, states[0] = -94.291874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227950795, states[0] = -94.286990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236646178, states[0] = -94.297886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244706261, states[0] = -93.636306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251830650, states[0] = -94.290602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259831385, states[0] = -94.165995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267847527, states[0] = -94.311564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275711753, states[0] = -94.294667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284030265, states[0] = -94.308195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291946597, states[0] = -94.306341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300296196, states[0] = -94.084970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308288976, states[0] = -94.313574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316768766, states[0] = -93.993392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324125225, states[0] = -20.199724, states[40]= 0.000331
Saving checkpoint... 
Iteration: 332983010, states[0] = -94.284479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342207776, states[0] = -93.646490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350327308, states[0] = -94.311174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358163890, states[0] = -94.295254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366066422, states[0] = 19.658564, states[40]= 0.000002
Saving checkpoint... 
Iteration: 374942858, states[0] = -94.284964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382320808, states[0] = -94.288832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390670416, states[0] = -94.315399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399145478, states[0] = -42.404397, states[40]= 0.000264
Saving checkpoint... 
Iteration: 406814754, states[0] = -94.129742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414632053, states[0] = -94.314665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423100421, states[0] = 2.515609, states[40]= 0.000156
Saving checkpoint... 
Iteration: 432111921, states[0] = -6.443530, states[40]= 0.000320
Saving checkpoint... 
Iteration: 439991026, states[0] = -94.296699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448292143, states[0] = -94.288716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456646523, states[0] = -94.314187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464211871, states[0] = -94.313538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471911106, states[0] = -94.305038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479485569, states[0] = -94.301250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488178543, states[0] = -94.313676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496544882, states[0] = 25.398338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504490206, states[0] = -94.295356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512847877, states[0] = -94.285650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520285732, states[0] = -94.287710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527939502, states[0] = -94.282430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536031247, states[0] = -94.304082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543868067, states[0] = -94.305912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551082182, states[0] = -94.309936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558783095, states[0] = -94.309533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566983135, states[0] = -94.280452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575054682, states[0] = -94.306814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583357874, states[0] = -94.284098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591280526, states[0] = -94.031528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599144610, states[0] = -94.311718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607290222, states[0] = -94.286050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615523754, states[0] = -94.301371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623829492, states[0] = -94.284368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631898140, states[0] = -94.244987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640873553, states[0] = -94.220717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648348544, states[0] = -94.187945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655653426, states[0] = -51.760989, states[40]= 0.000098
Saving checkpoint... 
Iteration: 663581970, states[0] = -94.307984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671183014, states[0] = -94.310480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679155738, states[0] = -94.290070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688041747, states[0] = -94.294983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695668030, states[0] = -94.289276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704078016, states[0] = -94.306975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711906550, states[0] = -94.301135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720278621, states[0] = -94.022730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729158695, states[0] = -57.917540, states[40]= 0.000045
Saving checkpoint... 
Iteration: 737529790, states[0] = -94.294689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746043796, states[0] = -94.302432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753474395, states[0] = -94.286018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761715234, states[0] = -94.286224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769767307, states[0] = -93.979700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777772332, states[0] = -94.306198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787143575, states[0] = -94.288723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795204645, states[0] = -93.613678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804070050, states[0] = 18.262242, states[40]= 0.000004
Saving checkpoint... 
Iteration: 812674417, states[0] = -94.286998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820969891, states[0] = -94.283239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829291972, states[0] = -94.282164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838274331, states[0] = -94.282654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846566937, states[0] = -94.303508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854767941, states[0] = -94.282606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863908527, states[0] = -94.277609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871134817, states[0] = -94.287658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879182551, states[0] = -90.871986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887243459, states[0] = -94.305373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894892146, states[0] = -94.298702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902671823, states[0] = -94.285559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910767443, states[0] = -93.977775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919039852, states[0] = -94.291099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926759798, states[0] = -94.281672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934488534, states[0] = -94.273966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943277091, states[0] = -94.280743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951427635, states[0] = -94.260744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960211723, states[0] = -93.665043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967895085, states[0] = -94.236553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975880777, states[0] = -94.297865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983799904, states[0] = -94.279216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992125758, states[0] = -94.304585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000508023, states[0] = 19.329156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1008891225, states[0] = -94.296787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016787914, states[0] = -94.279083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025811028, states[0] = -94.278095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034245104, states[0] = -94.302789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042320972, states[0] = -94.277459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051138346, states[0] = -94.284407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059424510, states[0] = -94.256954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067385730, states[0] = -94.296046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076920145, states[0] = -94.273571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084389474, states[0] = -94.274422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092784320, states[0] = -94.300307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101232181, states[0] = -93.799532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109586706, states[0] = -94.285670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116865364, states[0] = -94.296194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126062483, states[0] = -94.286486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134518854, states[0] = -94.291492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143399677, states[0] = -94.237460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151529325, states[0] = -94.287590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159409544, states[0] = -94.272483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167341045, states[0] = -94.167169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176506431, states[0] = -94.288052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184365586, states[0] = -94.295017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193126103, states[0] = -94.301136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200795896, states[0] = -94.297961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208923836, states[0] = -94.271183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217614325, states[0] = -94.282584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225407701, states[0] = -94.271408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234062552, states[0] = -94.284622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242886661, states[0] = -94.292981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251047669, states[0] = 24.946614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259916704, states[0] = -94.270524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269088505, states[0] = 9.596357, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1276857086, states[0] = -94.189301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283888710, states[0] = -94.271006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291872247, states[0] = -94.207987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300497711, states[0] = -94.267388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308239880, states[0] = -93.840432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316539682, states[0] = -94.284263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323875561, states[0] = -94.292135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332375654, states[0] = -94.211115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340608980, states[0] = -94.280701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348878247, states[0] = -94.213638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357622419, states[0] = -17.174219, states[40]= 0.000302
Saving checkpoint... 
Iteration: 1365691613, states[0] = -94.298438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372830306, states[0] = -94.144805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381254525, states[0] = -94.274043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389809581, states[0] = -94.294115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397610074, states[0] = -94.279673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406523001, states[0] = -94.283506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414788824, states[0] = -94.043938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422835843, states[0] = -94.292346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431193728, states[0] = -93.450791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439599476, states[0] = -94.279418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447636074, states[0] = -31.756591, states[40]= 0.000510
Saving checkpoint... 
Iteration: 1456656052, states[0] = -54.809474, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1464686128, states[0] = -94.296811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472989168, states[0] = -94.264667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482376712, states[0] = -94.209679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489955700, states[0] = -94.266002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498386662, states[0] = -94.267383, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.139849
 - CaMKt in component CaMK (millimolar): 0.003717
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 7.285627
 - nass in component intracellular_ions (millimolar): 7.285769
 - ki in component intracellular_ions (millimolar): 144.335793
 - kss in component intracellular_ions (millimolar): 144.335775
 - cansr in component intracellular_ions (millimolar): 2.487392
 - cajsr in component intracellular_ions (millimolar): 2.488068
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003908
 - hf in component INa (dimensionless): 0.866136
 - hs in component INa (dimensionless): 0.866137
 - j in component INa (dimensionless): 0.866144
 - hsp in component INa (dimensionless): 0.700256
 - jp in component INa (dimensionless): 0.866148
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708690
 - hLp in component INaL (dimensionless): 0.512522
 - a in component Ito (dimensionless): 0.000656
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.999851
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999851
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991065
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005478
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.025132
 - xs1 in component IKs (dimensionless): 0.069297
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997530
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:23:22 (66222): called boinc_finish(0)

</stderr_txt>
]]>


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