𝕏

Task 55761334

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_K1_75-conf_79_0
Workunit 26478829
Created 2 Jul 2024, 14:02:34 UTC
Sent 2 Jul 2024, 20:44:14 UTC
Report deadline 5 Jul 2024, 23:37:02 UTC
Received 3 Jul 2024, 12:46:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222286
Run time 2 hours 51 min 13 sec
CPU time 2 hours 25 min 4 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 5.11 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.67 MB
Peak swap size 32.63 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_K1_75-conf_79.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_K1_75-conf_79_0_r991060316_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_K1_75-conf_79_0_r991060316_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.630465
     * GNaL_b in INaL: 0.005528
     * Gto_b in Ito: 0.082557
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032021
     * GKs_b in IKs: 0.001934
     * GK1_b in IK1: 0.041502
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.291670
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030354
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14682762, states[0] = -78.628965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27644863, states[0] = -56.622406, states[40]= 0.000024
Saving checkpoint... 
Iteration: 40621455, states[0] = -34.908112, states[40]= 0.000574
Saving checkpoint... 
Iteration: 55040204, states[0] = 21.204512, states[40]= 0.001966
Saving checkpoint... 
Iteration: 66700606, states[0] = -81.742986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79667721, states[0] = -69.328689, states[40]= 0.000002
Saving checkpoint... 
Iteration: 93657756, states[0] = -63.850819, states[40]= 0.000007
Saving checkpoint... 
Iteration: 109229374, states[0] = -87.409944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124747733, states[0] = -89.155413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140016705, states[0] = 27.897078, states[40]= 0.005757
Saving checkpoint... 
Iteration: 153707699, states[0] = -83.277520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169787922, states[0] = -90.505594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184042161, states[0] = 20.640679, states[40]= 0.002120
Saving checkpoint... 
Iteration: 198999588, states[0] = -91.345910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213839260, states[0] = -90.977088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228244991, states[0] = -88.926614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241444703, states[0] = -91.292818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256361617, states[0] = -91.083240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270581351, states[0] = 2.608499, states[40]= 0.004480
Saving checkpoint... 
Iteration: 284891666, states[0] = -91.185198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298856059, states[0] = -91.059003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312279811, states[0] = -90.353234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326014780, states[0] = 28.047769, states[40]= 0.010049
Saving checkpoint... 
Iteration: 342107480, states[0] = -20.171415, states[40]= 0.001211
Saving checkpoint... 
Iteration: 355477030, states[0] = -91.327175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368227576, states[0] = -87.080814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382075877, states[0] = 5.796039, states[40]= 0.004403
Saving checkpoint... 
Iteration: 394758649, states[0] = -89.713662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406992552, states[0] = -91.338467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422365031, states[0] = -91.095724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438249219, states[0] = -89.214593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452000360, states[0] = -46.346691, states[40]= 0.000003
Saving checkpoint... 
Iteration: 466200023, states[0] = -81.203965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481625214, states[0] = -37.307109, states[40]= 0.000449
Saving checkpoint... 
Iteration: 495073236, states[0] = 7.211825, states[40]= 0.004301
Saving checkpoint... 
Iteration: 509378144, states[0] = -91.142722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524308206, states[0] = -90.747403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538433976, states[0] = -91.274753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553720453, states[0] = -85.942108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569166028, states[0] = -68.197891, states[40]= 0.000003
Saving checkpoint... 
Iteration: 583290461, states[0] = -90.536345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597127452, states[0] = -39.406473, states[40]= 0.000348
Saving checkpoint... 
Iteration: 611831681, states[0] = -90.928704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626283422, states[0] = -90.420859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641322419, states[0] = -90.865771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656760258, states[0] = -89.780261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670124605, states[0] = -36.732797, states[40]= 0.000480
Saving checkpoint... 
Iteration: 680962804, states[0] = -91.312094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693277212, states[0] = -90.295872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707079212, states[0] = 3.901128, states[40]= 0.004476
Saving checkpoint... 
Iteration: 720265361, states[0] = -89.970204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732312842, states[0] = -90.788808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745978326, states[0] = -91.326411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758528642, states[0] = 25.336660, states[40]= 0.001522
Saving checkpoint... 
Iteration: 772627910, states[0] = -39.833918, states[40]= 0.000329
Saving checkpoint... 
Iteration: 785737248, states[0] = -88.244988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798908989, states[0] = -91.225943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811895515, states[0] = -91.192995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824546748, states[0] = 18.890746, states[40]= 0.002430
Saving checkpoint... 
Iteration: 836596532, states[0] = -9.187692, states[40]= 0.002761
Saving checkpoint... 
Iteration: 849405214, states[0] = -91.217060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862596507, states[0] = -9.163700, states[40]= 0.002766
Saving checkpoint... 
Iteration: 876935296, states[0] = -91.275267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891220374, states[0] = -85.925555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903206692, states[0] = -82.990595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915743417, states[0] = -88.798425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929437893, states[0] = -91.279040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944417526, states[0] = -91.243316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957793014, states[0] = -90.570846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972782694, states[0] = -90.405669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987249525, states[0] = -89.230401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001377551, states[0] = -91.138420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017036413, states[0] = 22.757235, states[40]= 0.001795
Saving checkpoint... 
Iteration: 1030876124, states[0] = -91.133464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043938900, states[0] = -91.280025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055703815, states[0] = -82.245819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071360791, states[0] = -91.075491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085114584, states[0] = -27.156855, states[40]= 0.001022
Saving checkpoint... 
Iteration: 1099002928, states[0] = 37.531177, states[40]= 0.444239
Saving checkpoint... 
Iteration: 1114293301, states[0] = -90.573988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128154270, states[0] = -61.465607, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1143473143, states[0] = -91.320070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158507810, states[0] = 28.326780, states[40]= 0.097277
Saving checkpoint... 
Iteration: 1173148237, states[0] = -57.305274, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1187481364, states[0] = -91.326808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201020500, states[0] = 27.367807, states[40]= 0.002463
Saving checkpoint... 
Iteration: 1215451390, states[0] = -91.296397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229052127, states[0] = 16.763606, states[40]= 0.002831
Saving checkpoint... 
Iteration: 1243796826, states[0] = -90.619384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258059350, states[0] = 13.759023, states[40]= 0.003397
Saving checkpoint... 
Iteration: 1271664221, states[0] = -67.263182, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1286451020, states[0] = -91.295599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300383381, states[0] = -91.155800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315525588, states[0] = 26.206811, states[40]= 0.001560
Saving checkpoint... 
Iteration: 1329121954, states[0] = -34.222717, states[40]= 0.000628
Saving checkpoint... 
Iteration: 1342643981, states[0] = -54.043929, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1356819791, states[0] = -90.842598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372369644, states[0] = -91.108822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385407719, states[0] = -91.220327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400092754, states[0] = -5.731329, states[40]= 0.003509
Saving checkpoint... 
Iteration: 1414034490, states[0] = 23.432900, states[40]= 0.001704
Saving checkpoint... 
Iteration: 1429087032, states[0] = -1.184126, states[40]= 0.004249
Saving checkpoint... 
Iteration: 1441885379, states[0] = -91.161257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453705424, states[0] = -82.664252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465872049, states[0] = -91.117151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478696751, states[0] = -80.235476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493463214, states[0] = -91.308735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505548676, states[0] = -93.132578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517528596, states[0] = -0.155755, states[40]= 0.004428
Saving checkpoint... 
Iteration: 1528881884, states[0] = -44.649788, states[40]= 0.000208
Saving checkpoint... 
Iteration: 1538882885, states[0] = -90.513631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551695969, states[0] = -90.557341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564968944, states[0] = -89.833189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579515025, states[0] = -89.797165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594881495, states[0] = -88.582644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609396353, states[0] = -88.699221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623192459, states[0] = -88.237923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638541162, states[0] = -87.678611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652831002, states[0] = -85.540961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667195390, states[0] = -86.724963, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -86.437084
 - CaMKt in component CaMK (millimolar): 0.001072
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.154320
 - nass in component intracellular_ions (millimolar): 6.154402
 - ki in component intracellular_ions (millimolar): 145.751513
 - kss in component intracellular_ions (millimolar): 145.751501
 - cansr in component intracellular_ions (millimolar): 1.525993
 - cajsr in component intracellular_ions (millimolar): 1.526101
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.008488
 - hf in component INa (dimensionless): 0.646014
 - hs in component INa (dimensionless): 0.646029
 - j in component INa (dimensionless): 0.646100
 - hsp in component INa (dimensionless): 0.397242
 - jp in component INa (dimensionless): 0.646142
 - mL in component INaL (dimensionless): 0.000248
 - hL in component INaL (dimensionless): 0.465639
 - hLp in component INaL (dimensionless): 0.277257
 - a in component Ito (dimensionless): 0.001103
 - iF in component Ito (dimensionless): 0.999426
 - iS in component Ito (dimensionless): 0.995006
 - ap in component Ito (dimensionless): 0.000562
 - iFp in component Ito (dimensionless): 0.999426
 - iSp in component Ito (dimensionless): 0.997291
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998860
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002704
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.008807
 - xs1 in component IKs (dimensionless): 0.023769
 - xs2 in component IKs (dimensionless): 0.000226
 - xk1 in component IK1 (dimensionless): 0.998847
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:11:13 (7989): called boinc_finish(0)

</stderr_txt>
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