𝕏

Task 55759736

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_5000-conf_777_1
Workunit 26478033
Created 2 Jul 2024, 14:01:46 UTC
Sent 2 Jul 2024, 20:30:33 UTC
Report deadline 5 Jul 2024, 20:30:33 UTC
Received 3 Jul 2024, 3:48:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 41 min 1 sec
CPU time 1 hours 35 min 4 sec
Validate state Valid
Credit 44.45
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.76 MB
Peak swap size 4.13 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_5000-conf_777.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_5000-conf_777_1_r1122259289_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_5000-conf_777_1_r1122259289_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.782453
     * GNaL_b in INaL: 0.006229
     * Gto_b in Ito: 0.087916
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031359
     * GKs_b in IKs: 0.001901
     * GK1_b in IK1: 0.165624
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.283214
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030046
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11202585, states[0] = -94.226835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22588918, states[0] = 22.546413, states[40]= 0.000002
Saving checkpoint... 
Iteration: 33375701, states[0] = -94.209170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 44647946, states[0] = -94.184438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 55542709, states[0] = -94.174891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66563261, states[0] = -94.221185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 77009743, states[0] = -94.219246, states[40]= 0.000001
Saving checkpoint... 
Iteration: 87261753, states[0] = -94.220885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 98389350, states[0] = -94.252954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 109148781, states[0] = -94.235135, states[40]= 0.000001
Saving checkpoint... 
Iteration: 119563972, states[0] = -94.230732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 130729405, states[0] = -94.255190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 142609744, states[0] = 12.885191, states[40]= 0.000024
Saving checkpoint... 
Iteration: 154308980, states[0] = -94.237758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 166393193, states[0] = -94.247157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177854713, states[0] = -93.928478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188664614, states[0] = -94.254651, states[40]= 0.000001
Saving checkpoint... 
Iteration: 199793468, states[0] = -94.233802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 211726425, states[0] = -94.240800, states[40]= 0.000001
Saving checkpoint... 
Iteration: 223917577, states[0] = -94.247583, states[40]= 0.000001
Saving checkpoint... 
Iteration: 235965593, states[0] = -94.261054, states[40]= 0.000001
Saving checkpoint... 
Iteration: 248397877, states[0] = -94.262366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 261156896, states[0] = -94.255232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 273816192, states[0] = -94.250273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 286860905, states[0] = -94.238519, states[40]= 0.000001
Saving checkpoint... 
Iteration: 299460961, states[0] = -94.237064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311915350, states[0] = -94.237573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 324714776, states[0] = -94.234190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 336987263, states[0] = -94.236445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 349900162, states[0] = -94.232612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 362758480, states[0] = -56.092023, states[40]= 0.000243
Saving checkpoint... 
Iteration: 375862013, states[0] = -94.261794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 388703548, states[0] = -94.252790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 400575185, states[0] = -94.227689, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413714999, states[0] = -94.252211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 426858110, states[0] = -94.237406, states[40]= 0.000001
Saving checkpoint... 
Iteration: 439645472, states[0] = -94.233830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 451801813, states[0] = -94.238049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 463953870, states[0] = -94.244993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 476821485, states[0] = -94.237517, states[40]= 0.000001
Saving checkpoint... 
Iteration: 489312351, states[0] = -94.237549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 501886644, states[0] = -94.236327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 515375346, states[0] = -93.991430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527871923, states[0] = -93.981812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541092213, states[0] = -94.254994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 552898701, states[0] = -94.047662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565290408, states[0] = -92.688072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577663897, states[0] = -9.219334, states[40]= 0.000677
Saving checkpoint... 
Iteration: 590415805, states[0] = -94.080930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603463159, states[0] = -94.258192, states[40]= 0.000001
Saving checkpoint... 
Iteration: 616132704, states[0] = -94.253031, states[40]= 0.000001
Saving checkpoint... 
Iteration: 628470385, states[0] = -94.257791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641517850, states[0] = -94.241874, states[40]= 0.000001
Saving checkpoint... 
Iteration: 654872385, states[0] = -94.230092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 667524853, states[0] = 33.484211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679710896, states[0] = -94.231096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 693112929, states[0] = -94.237287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 706059270, states[0] = -94.254560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 718746102, states[0] = -94.248537, states[40]= 0.000001
Saving checkpoint... 
Iteration: 730928854, states[0] = -94.257813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 743217854, states[0] = -94.253944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756411778, states[0] = -94.243470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 769528981, states[0] = -94.232121, states[40]= 0.000001
Saving checkpoint... 
Iteration: 781495565, states[0] = -94.241150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 794018263, states[0] = -94.240506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 807064288, states[0] = -94.231390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 818797488, states[0] = -94.246100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 832076783, states[0] = -94.231032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 845346051, states[0] = -93.894974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857803325, states[0] = -93.691501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871109760, states[0] = -94.251496, states[40]= 0.000001
Saving checkpoint... 
Iteration: 883824957, states[0] = -94.244722, states[40]= 0.000001
Saving checkpoint... 
Iteration: 896716716, states[0] = -94.235527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909158305, states[0] = -94.236506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 921860043, states[0] = -94.232969, states[40]= 0.000001
Saving checkpoint... 
Iteration: 934645503, states[0] = -94.229419, states[40]= 0.000001
Saving checkpoint... 
Iteration: 947862992, states[0] = -93.951515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960394017, states[0] = -94.033688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973867633, states[0] = -94.242719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 986594613, states[0] = -94.237101, states[40]= 0.000001
Saving checkpoint... 
Iteration: 999860068, states[0] = -94.227096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1012909872, states[0] = -94.066108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025093691, states[0] = 18.578005, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1037909969, states[0] = -94.066069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051452605, states[0] = -94.239794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1064194221, states[0] = -94.234443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1077437909, states[0] = -94.225915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1089545613, states[0] = -94.229077, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1101450543, states[0] = -94.239400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1114705415, states[0] = -94.227263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1127918179, states[0] = -94.080294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141103136, states[0] = -94.249305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1154747080, states[0] = -94.226555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1167594103, states[0] = 18.430026, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1180492885, states[0] = -94.172559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193507693, states[0] = -94.251762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1206070276, states[0] = -94.249768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1219292049, states[0] = -94.231368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1231922959, states[0] = -94.229320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1244136466, states[0] = -94.233950, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1257508071, states[0] = 27.119910, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1270633866, states[0] = -94.237197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1283398752, states[0] = -94.253400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1295756254, states[0] = -94.251598, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1307457064, states[0] = -94.223756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320716747, states[0] = -94.248710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332708588, states[0] = -26.536217, states[40]= 0.006849
Saving checkpoint... 
Iteration: 1344727074, states[0] = -94.225028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1357089541, states[0] = -94.226216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1369894019, states[0] = -94.223575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1381584541, states[0] = -94.233796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1394634070, states[0] = -94.225429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1407651808, states[0] = -3.194711, states[40]= 0.000484
Saving checkpoint... 
Iteration: 1420840715, states[0] = -94.252516, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1433150694, states[0] = -94.239106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445777502, states[0] = -94.251165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459037070, states[0] = -94.234150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1471293504, states[0] = -94.240408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1484035449, states[0] = -94.233964, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1495922449, states[0] = -94.251128, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.097780
 - CaMKt in component CaMK (millimolar): 0.001823
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 7.821849
 - nass in component intracellular_ions (millimolar): 7.822002
 - ki in component intracellular_ions (millimolar): 143.991281
 - kss in component intracellular_ions (millimolar): 143.991267
 - cansr in component intracellular_ions (millimolar): 1.804386
 - cajsr in component intracellular_ions (millimolar): 1.805911
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003924
 - hf in component INa (dimensionless): 0.865332
 - hs in component INa (dimensionless): 0.865333
 - j in component INa (dimensionless): 0.865334
 - hsp in component INa (dimensionless): 0.698797
 - jp in component INa (dimensionless): 0.865334
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707458
 - hLp in component INaL (dimensionless): 0.513638
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.997164
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999019
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998006
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004445
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002467
 - xs1 in component IKs (dimensionless): 0.032905
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997540
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:45:15 (24960): called boinc_finish(0)

</stderr_txt>
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