𝕏

Task 55758760

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_4000-conf_676_1
Workunit 26477545
Created 2 Jul 2024, 14:01:20 UTC
Sent 2 Jul 2024, 20:30:33 UTC
Report deadline 5 Jul 2024, 20:30:33 UTC
Received 3 Jul 2024, 3:48:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 40 min 40 sec
CPU time 1 hours 34 min 49 sec
Validate state Valid
Credit 42.26
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.43 MB
Peak swap size 4.13 GB
Peak disk usage 1.25 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_4000-conf_676.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_4000-conf_676_1_r125076686_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_4000-conf_676_1_r125076686_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.159968
     * GNaL_b in INaL: 0.005613
     * Gto_b in Ito: 0.085685
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032261
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.166232
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.190826
     * GKb_b in IKb: 0.003808
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035404
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11161908, states[0] = -86.811472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21795545, states[0] = -86.730344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32678779, states[0] = -86.688375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43333536, states[0] = -86.648039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53734072, states[0] = -86.619328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64747292, states[0] = -86.612559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75806031, states[0] = -86.585976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87126414, states[0] = -86.583845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98512902, states[0] = -86.567850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109545824, states[0] = -86.564376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120399490, states[0] = -86.528202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131806150, states[0] = -86.554340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142926987, states[0] = -86.563953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153364427, states[0] = -86.554764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164849223, states[0] = -86.561770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175997952, states[0] = -86.546089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186564356, states[0] = -86.553554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198381456, states[0] = -86.508437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210169089, states[0] = -60.839488, states[40]= 0.000004
Saving checkpoint... 
Iteration: 222241652, states[0] = -86.368149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234028566, states[0] = 20.746409, states[40]= 0.005115
Saving checkpoint... 
Iteration: 245393401, states[0] = -86.548762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256571420, states[0] = -86.551929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267935101, states[0] = -86.543209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280400533, states[0] = -86.515394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292760392, states[0] = -86.557823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305402881, states[0] = -86.548094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318037727, states[0] = 19.010767, states[40]= 0.004383
Saving checkpoint... 
Iteration: 330595361, states[0] = -86.553299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343258450, states[0] = -86.550141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356291303, states[0] = -86.435997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368751696, states[0] = -86.557612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381347242, states[0] = -86.548726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393351677, states[0] = -86.548652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406319222, states[0] = -86.464271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419368804, states[0] = -86.548392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432548118, states[0] = -86.549144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445442270, states[0] = -86.547385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457816199, states[0] = -86.543609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470296036, states[0] = -86.441247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482623816, states[0] = -86.554808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496130843, states[0] = -26.210840, states[40]= 0.000678
Saving checkpoint... 
Iteration: 509171865, states[0] = -86.551506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521912397, states[0] = -86.542905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534394646, states[0] = -86.512517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546303959, states[0] = -86.449641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559369354, states[0] = -86.548347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572359288, states[0] = -86.494004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586129855, states[0] = -25.380010, states[40]= 0.000714
Saving checkpoint... 
Iteration: 599693643, states[0] = -86.544603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613007460, states[0] = -86.554478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626072673, states[0] = 9.343266, states[40]= 0.004179
Saving checkpoint... 
Iteration: 638066535, states[0] = 11.344960, states[40]= 0.004207
Saving checkpoint... 
Iteration: 649795927, states[0] = -86.543726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662485965, states[0] = -86.539973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675394168, states[0] = -86.547977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688604122, states[0] = -86.553699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701272770, states[0] = -86.549776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713792179, states[0] = -86.543744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727461740, states[0] = -86.547077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740232821, states[0] = -86.352959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752480096, states[0] = -86.538792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765695868, states[0] = -86.544551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778617266, states[0] = -86.554421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791078976, states[0] = -86.553128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804458327, states[0] = -86.533875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817298665, states[0] = -86.549348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830446631, states[0] = -86.530806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843087653, states[0] = -86.552959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855785760, states[0] = -86.543768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868960303, states[0] = -86.555272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882697480, states[0] = -86.557000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895572316, states[0] = -86.545753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908537130, states[0] = -86.547797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921952936, states[0] = -86.542564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934589442, states[0] = -86.552690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947355002, states[0] = -86.548479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960379898, states[0] = -86.505441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973035308, states[0] = -86.553899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986286580, states[0] = -86.430301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998769433, states[0] = -86.557467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011458617, states[0] = -86.547063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025152678, states[0] = -86.551747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037809850, states[0] = -86.543544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050949779, states[0] = -86.555419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063930981, states[0] = -86.542679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077037300, states[0] = -86.553843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089658395, states[0] = -86.544840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102211015, states[0] = -86.313386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114718031, states[0] = -86.557229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127702774, states[0] = -86.544421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140168119, states[0] = -59.718807, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1152895547, states[0] = -86.556272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166132309, states[0] = -27.445927, states[40]= 0.000620
Saving checkpoint... 
Iteration: 1179625546, states[0] = -86.545145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192421448, states[0] = -86.522924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205261382, states[0] = -86.549864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217502764, states[0] = -86.546482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230057695, states[0] = 13.962621, states[40]= 0.004198
Saving checkpoint... 
Iteration: 1243797504, states[0] = -86.543602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256361151, states[0] = -86.495007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269606176, states[0] = -86.545325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282308560, states[0] = -86.454116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296165925, states[0] = -57.485847, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1310104848, states[0] = -5.389983, states[40]= 0.002840
Saving checkpoint... 
Iteration: 1323228112, states[0] = -86.550388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336341162, states[0] = -86.481750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348856224, states[0] = -86.556768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361725155, states[0] = -86.544179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374441984, states[0] = -86.529392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386680938, states[0] = -86.556589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399053190, states[0] = -86.553489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410806124, states[0] = -86.557239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422138827, states[0] = -32.977869, states[40]= 0.000345
Saving checkpoint... 
Iteration: 1435530973, states[0] = -86.546111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448676967, states[0] = -86.556487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459941177, states[0] = -86.542538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471273020, states[0] = -86.549627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484170337, states[0] = -62.068428, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1497317780, states[0] = -86.548927, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.418136
 - CaMKt in component CaMK (millimolar): 0.000885
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.016699
 - nass in component intracellular_ions (millimolar): 6.016744
 - ki in component intracellular_ions (millimolar): 145.979975
 - kss in component intracellular_ions (millimolar): 145.979965
 - cansr in component intracellular_ions (millimolar): 1.246408
 - cajsr in component intracellular_ions (millimolar): 1.246558
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008505
 - hf in component INa (dimensionless): 0.645302
 - hs in component INa (dimensionless): 0.645302
 - j in component INa (dimensionless): 0.645305
 - hsp in component INa (dimensionless): 0.396451
 - jp in component INa (dimensionless): 0.645307
 - mL in component INaL (dimensionless): 0.000248
 - hL in component INaL (dimensionless): 0.464432
 - hLp in component INaL (dimensionless): 0.274525
 - a in component Ito (dimensionless): 0.001105
 - iF in component Ito (dimensionless): 0.999424
 - iS in component Ito (dimensionless): 0.985572
 - ap in component Ito (dimensionless): 0.000563
 - iFp in component Ito (dimensionless): 0.999424
 - iSp in component Ito (dimensionless): 0.991677
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997501
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001252
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020124
 - xs1 in component IKs (dimensionless): 0.037229
 - xs2 in component IKs (dimensionless): 0.000227
 - xk1 in component IK1 (dimensionless): 0.997121
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:38:36 (24898): called boinc_finish(0)

</stderr_txt>
]]>