𝕏

Task 55757721

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_500-conf_375_0
Workunit 26477026
Created 2 Jul 2024, 14:00:49 UTC
Sent 2 Jul 2024, 20:15:05 UTC
Report deadline 5 Jul 2024, 20:15:05 UTC
Received 3 Jul 2024, 10:59:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235353
Run time 2 hours 54 min 51 sec
CPU time 1 hours 54 min 24 sec
Validate state Valid
Credit 44.75
Device peak FLOPS 4.99 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.19 MB
Peak swap size 5.27 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_500-conf_375.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_500-conf_375_0_r2047457329_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_500-conf_375_0_r2047457329_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.492108
     * GNaL_b in INaL: 0.005441
     * Gto_b in Ito: 0.084941
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031595
     * GKs_b in IKs: 0.001901
     * GK1_b in IK1: 0.161078
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.528647
     * GKb_b in IKb: 0.003814
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028762
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9686900, states[0] = -87.366047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19213493, states[0] = -87.384681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27827623, states[0] = -22.056514, states[40]= 0.000896
Saving checkpoint... 
Iteration: 36550111, states[0] = 5.199227, states[40]= 0.005590
Saving checkpoint... 
Iteration: 45064553, states[0] = -6.310623, states[40]= 0.003674
Saving checkpoint... 
Iteration: 53662648, states[0] = -87.238911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63201154, states[0] = -87.329516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71740216, states[0] = -87.389552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80356889, states[0] = -57.197125, states[40]= 0.000009
Saving checkpoint... 
Iteration: 89194581, states[0] = -87.311861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98901944, states[0] = -87.196577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107508647, states[0] = 24.028910, states[40]= 0.062986
Saving checkpoint... 
Iteration: 116310478, states[0] = -2.183751, states[40]= 0.004595
Saving checkpoint... 
Iteration: 124690437, states[0] = -87.300765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133272102, states[0] = 20.053191, states[40]= 0.008775
Saving checkpoint... 
Iteration: 142944077, states[0] = -87.308204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151404341, states[0] = -87.203207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160048538, states[0] = 6.472419, states[40]= 0.005689
Saving checkpoint... 
Iteration: 168410235, states[0] = -87.221719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179622747, states[0] = -80.120160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189565580, states[0] = -6.993376, states[40]= 0.003502
Saving checkpoint... 
Iteration: 198632596, states[0] = -86.535633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208023026, states[0] = 19.708375, states[40]= 0.008384
Saving checkpoint... 
Iteration: 217364817, states[0] = -68.094776, states[40]= 0.000002
Saving checkpoint... 
Iteration: 227544658, states[0] = 8.848160, states[40]= 0.005869
Saving checkpoint... 
Iteration: 236947423, states[0] = -87.314594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246293917, states[0] = 9.286091, states[40]= 0.005903
Saving checkpoint... 
Iteration: 255365037, states[0] = -68.426067, states[40]= 0.000001
Saving checkpoint... 
Iteration: 264405066, states[0] = -87.205149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274542709, states[0] = 9.990217, states[40]= 0.005958
Saving checkpoint... 
Iteration: 283356343, states[0] = -56.282636, states[40]= 0.000011
Saving checkpoint... 
Iteration: 292505602, states[0] = 26.497713, states[40]= 0.117351
Saving checkpoint... 
Iteration: 301594460, states[0] = -41.435493, states[40]= 0.000106
Saving checkpoint... 
Iteration: 311593163, states[0] = -39.869217, states[40]= 0.000133
Saving checkpoint... 
Iteration: 320696981, states[0] = -87.313579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329883624, states[0] = -86.690897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338974521, states[0] = -87.362227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347952032, states[0] = -87.323645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358237297, states[0] = -87.380102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367201261, states[0] = -87.322120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376104066, states[0] = -53.347767, states[40]= 0.000017
Saving checkpoint... 
Iteration: 385104876, states[0] = -54.384740, states[40]= 0.000015
Saving checkpoint... 
Iteration: 395229537, states[0] = -87.369505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404261096, states[0] = 23.241336, states[40]= 0.036644
Saving checkpoint... 
Iteration: 413250882, states[0] = 40.335578, states[40]= 0.022038
Saving checkpoint... 
Iteration: 422266529, states[0] = 21.874289, states[40]= 0.014215
Saving checkpoint... 
Iteration: 431464709, states[0] = -87.346504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441131226, states[0] = -86.246553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449907170, states[0] = -87.211754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458664978, states[0] = -87.235116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467480695, states[0] = -87.371065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478443219, states[0] = -87.305516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487221689, states[0] = -87.357739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496195375, states[0] = -87.310063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505066302, states[0] = -7.750308, states[40]= 0.003315
Saving checkpoint... 
Iteration: 514098885, states[0] = -46.846005, states[40]= 0.000048
Saving checkpoint... 
Iteration: 523995057, states[0] = -87.389595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532943255, states[0] = -87.305536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541952400, states[0] = -87.324154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551153643, states[0] = -87.200007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560333265, states[0] = -27.980828, states[40]= 0.000544
Saving checkpoint... 
Iteration: 570293147, states[0] = 9.736551, states[40]= 0.005937
Saving checkpoint... 
Iteration: 579559525, states[0] = -1.351628, states[40]= 0.004750
Saving checkpoint... 
Iteration: 588707963, states[0] = -87.334538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598042927, states[0] = 9.864284, states[40]= 0.005948
Saving checkpoint... 
Iteration: 608197530, states[0] = -87.314401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617446079, states[0] = -87.311403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626740985, states[0] = -87.384521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635931908, states[0] = -87.279570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645041087, states[0] = 10.917599, states[40]= 0.006034
Saving checkpoint... 
Iteration: 655082775, states[0] = -27.388512, states[40]= 0.000574
Saving checkpoint... 
Iteration: 664393320, states[0] = -87.141929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673150673, states[0] = -87.188807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682233626, states[0] = -87.374884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692428147, states[0] = -87.270234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701302432, states[0] = 3.933975, states[40]= 0.005468
Saving checkpoint... 
Iteration: 710170948, states[0] = -87.251446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719168252, states[0] = -87.244061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728335446, states[0] = -30.609197, states[40]= 0.000420
Saving checkpoint... 
Iteration: 738515559, states[0] = 22.137621, states[40]= 0.016234
Saving checkpoint... 
Iteration: 747541487, states[0] = 10.690911, states[40]= 0.006015
Saving checkpoint... 
Iteration: 756654194, states[0] = -87.201687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765945366, states[0] = -87.309760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776064170, states[0] = -5.559208, states[40]= 0.003852
Saving checkpoint... 
Iteration: 785344095, states[0] = -40.993084, states[40]= 0.000113
Saving checkpoint... 
Iteration: 794348280, states[0] = -46.098657, states[40]= 0.000053
Saving checkpoint... 
Iteration: 803235880, states[0] = -87.377777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812044756, states[0] = 8.790622, states[40]= 0.005865
Saving checkpoint... 
Iteration: 822125210, states[0] = -82.913446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830592115, states[0] = -38.607402, states[40]= 0.000158
Saving checkpoint... 
Iteration: 839220021, states[0] = -87.354753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847755474, states[0] = 26.687348, states[40]= 0.119744
Saving checkpoint... 
Iteration: 857506603, states[0] = 25.335077, states[40]= 0.097793
Saving checkpoint... 
Iteration: 866150985, states[0] = -87.189853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874904061, states[0] = -87.201107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883746383, states[0] = -87.390788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892449886, states[0] = -87.318853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902267732, states[0] = 21.526722, states[40]= 0.012332
Saving checkpoint... 
Iteration: 910936406, states[0] = -87.289909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919632678, states[0] = -86.548021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928270913, states[0] = 20.489218, states[40]= 0.009412
Saving checkpoint... 
Iteration: 938644868, states[0] = -87.156266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948234498, states[0] = -87.375784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957592908, states[0] = -39.560957, states[40]= 0.000138
Saving checkpoint... 
Iteration: 966805359, states[0] = 1.879068, states[40]= 0.005241
Saving checkpoint... 
Iteration: 976048767, states[0] = 6.332349, states[40]= 0.005678
Saving checkpoint... 
Iteration: 986163420, states[0] = -87.230066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995304905, states[0] = 2.207690, states[40]= 0.005281
Saving checkpoint... 
Iteration: 1004262319, states[0] = 22.938087, states[40]= 0.028467
Saving checkpoint... 
Iteration: 1013117965, states[0] = -72.968456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024157654, states[0] = -87.212672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033352656, states[0] = -51.556414, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1042638960, states[0] = -87.059103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051889020, states[0] = -87.060935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061065349, states[0] = -6.749983, states[40]= 0.003562
Saving checkpoint... 
Iteration: 1071045372, states[0] = 8.422823, states[40]= 0.005837
Saving checkpoint... 
Iteration: 1080896363, states[0] = -87.166880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090609130, states[0] = -59.975423, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1100123671, states[0] = -81.262611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110604330, states[0] = -53.683477, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1119894066, states[0] = -87.149035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129127609, states[0] = -84.771045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138325277, states[0] = -18.257199, states[40]= 0.001263
Saving checkpoint... 
Iteration: 1147383371, states[0] = -86.655256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157539536, states[0] = 11.785501, states[40]= 0.006112
Saving checkpoint... 
Iteration: 1166208598, states[0] = -87.335083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175478808, states[0] = -87.367649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185032948, states[0] = 15.265875, states[40]= 0.006554
Saving checkpoint... 
Iteration: 1195262283, states[0] = 22.946792, states[40]= 0.028672
Saving checkpoint... 
Iteration: 1204614909, states[0] = -68.228345, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1213800986, states[0] = 4.900708, states[40]= 0.005558
Saving checkpoint... 
Iteration: 1222793314, states[0] = 9.639685, states[40]= 0.005930
Saving checkpoint... 
Iteration: 1231839473, states[0] = -35.438699, states[40]= 0.000240
Saving checkpoint... 
Iteration: 1241827147, states[0] = -20.543225, states[40]= 0.001025
Saving checkpoint... 
Iteration: 1251442746, states[0] = -87.303688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260743570, states[0] = -87.387039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269713820, states[0] = -87.344122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280045918, states[0] = 8.094045, states[40]= 0.005812
Saving checkpoint... 
Iteration: 1289271866, states[0] = 20.146054, states[40]= 0.008889
Saving checkpoint... 
Iteration: 1298371903, states[0] = -78.962902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307432444, states[0] = -87.280157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316345251, states[0] = -42.392708, states[40]= 0.000092
Saving checkpoint... 
Iteration: 1327323583, states[0] = -16.190768, states[40]= 0.001540
Saving checkpoint... 
Iteration: 1336950872, states[0] = -87.320338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346414030, states[0] = -87.231454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355744941, states[0] = -87.388588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365811800, states[0] = -3.318918, states[40]= 0.004362
Saving checkpoint... 
Iteration: 1374824220, states[0] = -16.966386, states[40]= 0.001428
Saving checkpoint... 
Iteration: 1383753094, states[0] = 33.283118, states[40]= 0.130850
Saving checkpoint... 
Iteration: 1392523663, states[0] = 19.460875, states[40]= 0.008155
Saving checkpoint... 
Iteration: 1401926511, states[0] = -87.265339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412844369, states[0] = -41.323415, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1422042066, states[0] = 10.360863, states[40]= 0.005987
Saving checkpoint... 
Iteration: 1431200257, states[0] = -87.319025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440194087, states[0] = -87.306357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450321164, states[0] = -13.274748, states[40]= 0.002047
Saving checkpoint... 
Iteration: 1459378058, states[0] = -85.028655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468375557, states[0] = -83.233514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477682841, states[0] = -87.280931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487826134, states[0] = -19.304426, states[40]= 0.001146
Saving checkpoint... 
Iteration: 1498357196, states[0] = -57.396488, states[40]= 0.000009
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.270060
 - CaMKt in component CaMK (millimolar): 0.019549
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 6.770973
 - nass in component intracellular_ions (millimolar): 6.771073
 - ki in component intracellular_ions (millimolar): 145.185354
 - kss in component intracellular_ions (millimolar): 145.185328
 - cansr in component intracellular_ions (millimolar): 1.429244
 - cajsr in component intracellular_ions (millimolar): 1.211012
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.007807
 - hf in component INa (dimensionless): 0.676659
 - hs in component INa (dimensionless): 0.676554
 - j in component INa (dimensionless): 0.675838
 - hsp in component INa (dimensionless): 0.430007
 - jp in component INa (dimensionless): 0.673869
 - mL in component INaL (dimensionless): 0.000211
 - hL in component INaL (dimensionless): 0.385708
 - hLp in component INaL (dimensionless): 0.180424
 - a in component Ito (dimensionless): 0.001043
 - iF in component Ito (dimensionless): 0.999504
 - iS in component Ito (dimensionless): 0.293091
 - ap in component Ito (dimensionless): 0.000531
 - iFp in component Ito (dimensionless): 0.999504
 - iSp in component Ito (dimensionless): 0.340661
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.858265
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991105
 - jca in component ICaL (dimensionless): 0.991431
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004224
 - xrf in component IKr (dimensionless): 0.001765
 - xrs in component IKr (dimensionless): 0.673594
 - xs1 in component IKs (dimensionless): 0.382613
 - xs2 in component IKs (dimensionless): 0.000215
 - xk1 in component IK1 (dimensionless): 0.996917
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:59:30 (17544): called boinc_finish(0)

</stderr_txt>
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