𝕏

Task 55756488

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_1000-conf_474_1
Workunit 26476409
Created 2 Jul 2024, 14:00:12 UTC
Sent 2 Jul 2024, 20:04:56 UTC
Report deadline 5 Jul 2024, 20:04:56 UTC
Received 5 Jul 2024, 13:30:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 40 min 56 sec
CPU time 38 min 3 sec
Validate state Valid
Credit 41.27
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.58 MB
Peak swap size 391.75 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_1000-conf_474.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_1000-conf_474_1_r325144751_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_1000-conf_474_1_r325144751_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 102.464949
     * GNaL_b in INaL: 0.006201
     * Gto_b in Ito: 0.083672
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031997
     * GKs_b in IKs: 0.001919
     * GK1_b in IK1: 0.166881
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.147147
     * GKb_b in IKb: 0.003778
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029995
     * celltype in environment: 2.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9694651, states[0] = -30.439832, states[40]= 0.006181
Saving checkpoint... 
Iteration: 18008086, states[0] = 31.040721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28101382, states[0] = 11.895522, states[40]= 0.000351
Saving checkpoint... 
Iteration: 39337451, states[0] = -94.332360, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50635293, states[0] = -8.972136, states[40]= 0.005348
Saving checkpoint... 
Iteration: 61357609, states[0] = -94.432612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 71303154, states[0] = -94.261796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 80886082, states[0] = -94.510147, states[40]= 0.000001
Saving checkpoint... 
Iteration: 90064988, states[0] = 24.399042, states[40]= 0.000020
Saving checkpoint... 
Iteration: 99798350, states[0] = -94.263144, states[40]= 0.000001
Saving checkpoint... 
Iteration: 110209000, states[0] = -59.333637, states[40]= 0.000794
Saving checkpoint... 
Iteration: 121238266, states[0] = -93.486905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 132497304, states[0] = -94.617578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 143651843, states[0] = -25.039446, states[40]= 0.019779
Saving checkpoint... 
Iteration: 151599549, states[0] = 8.608861, states[40]= 0.002095
Saving checkpoint... 
Iteration: 160760112, states[0] = -94.010871, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169618487, states[0] = -2.193646, states[40]= 0.007234
Saving checkpoint... 
Iteration: 179812062, states[0] = -94.337605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 189586916, states[0] = 14.570178, states[40]= 0.000554
Saving checkpoint... 
Iteration: 199115273, states[0] = -0.167084, states[40]= 0.006639
Saving checkpoint... 
Iteration: 209022105, states[0] = 35.169145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219351019, states[0] = -94.460600, states[40]= 0.000001
Saving checkpoint... 
Iteration: 228203322, states[0] = -55.857866, states[40]= 0.001333
Saving checkpoint... 
Iteration: 237482373, states[0] = -94.607118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 247654488, states[0] = -26.575043, states[40]= 0.021027
Saving checkpoint... 
Iteration: 256909275, states[0] = -94.554538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 267064165, states[0] = 24.316039, states[40]= 0.000024
Saving checkpoint... 
Iteration: 276149641, states[0] = -24.163871, states[40]= 0.018733
Saving checkpoint... 
Iteration: 285766752, states[0] = -94.056893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 297532292, states[0] = 34.158819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308083465, states[0] = 16.123781, states[40]= 0.000369
Saving checkpoint... 
Iteration: 317402896, states[0] = -94.540455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 328370343, states[0] = -94.490016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 338439181, states[0] = -94.572502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 346410463, states[0] = -94.545845, states[40]= 0.000001
Saving checkpoint... 
Iteration: 354691478, states[0] = -46.743070, states[40]= 0.004140
Saving checkpoint... 
Iteration: 364135391, states[0] = -15.032911, states[40]= 0.006309
Saving checkpoint... 
Iteration: 375670561, states[0] = -34.099755, states[40]= 0.014311
Saving checkpoint... 
Iteration: 387053962, states[0] = 28.145190, states[40]= 0.000004
Saving checkpoint... 
Iteration: 396369827, states[0] = -94.481354, states[40]= 0.000001
Saving checkpoint... 
Iteration: 405917285, states[0] = -94.546189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 415212481, states[0] = -64.268931, states[40]= 0.000406
Saving checkpoint... 
Iteration: 424630521, states[0] = -11.277526, states[40]= 0.006361
Saving checkpoint... 
Iteration: 434736521, states[0] = -93.375039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444729030, states[0] = -89.154710, states[40]= 0.000010
Saving checkpoint... 
Iteration: 455285127, states[0] = -94.169165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 465803640, states[0] = -94.269060, states[40]= 0.000001
Saving checkpoint... 
Iteration: 474315985, states[0] = -94.321924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 484190116, states[0] = -45.775733, states[40]= 0.004607
Saving checkpoint... 
Iteration: 492806936, states[0] = -94.281294, states[40]= 0.000001
Saving checkpoint... 
Iteration: 501823760, states[0] = -94.348153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 510865050, states[0] = -94.459077, states[40]= 0.000001
Saving checkpoint... 
Iteration: 521608436, states[0] = 3.854574, states[40]= 0.004577
Saving checkpoint... 
Iteration: 531923167, states[0] = -94.537594, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542902957, states[0] = -94.515101, states[40]= 0.000001
Saving checkpoint... 
Iteration: 554003315, states[0] = 21.261437, states[40]= 0.000031
Saving checkpoint... 
Iteration: 564923781, states[0] = -94.534364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 573731371, states[0] = -91.476257, states[40]= 0.000005
Saving checkpoint... 
Iteration: 583968802, states[0] = -94.562419, states[40]= 0.000001
Saving checkpoint... 
Iteration: 593432924, states[0] = -94.538875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 604644634, states[0] = -21.310822, states[40]= 0.013124
Saving checkpoint... 
Iteration: 615436920, states[0] = -94.539466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627363510, states[0] = -94.442647, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637638309, states[0] = -17.129117, states[40]= 0.007270
Saving checkpoint... 
Iteration: 647631156, states[0] = -11.734226, states[40]= 0.006249
Saving checkpoint... 
Iteration: 656100967, states[0] = 7.815118, states[40]= 0.002465
Saving checkpoint... 
Iteration: 663882056, states[0] = -94.472181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 673156657, states[0] = -27.574533, states[40]= 0.020878
Saving checkpoint... 
Iteration: 682998148, states[0] = -94.562436, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692865462, states[0] = -94.439144, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703303153, states[0] = -94.239558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 714135108, states[0] = -14.766668, states[40]= 0.006213
Saving checkpoint... 
Iteration: 723056214, states[0] = 27.356719, states[40]= 0.000006
Saving checkpoint... 
Iteration: 733818239, states[0] = -94.301057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 742682962, states[0] = -41.027226, states[40]= 0.007564
Saving checkpoint... 
Iteration: 751205954, states[0] = -58.087319, states[40]= 0.000977
Saving checkpoint... 
Iteration: 761611964, states[0] = 1.862207, states[40]= 0.005620
Saving checkpoint... 
Iteration: 771298398, states[0] = -94.208217, states[40]= 0.000001
Saving checkpoint... 
Iteration: 780985906, states[0] = -94.547300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 790068902, states[0] = 22.429719, states[40]= 0.000050
Saving checkpoint... 
Iteration: 799542075, states[0] = 31.932313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808697974, states[0] = -51.584328, states[40]= 0.002311
Saving checkpoint... 
Iteration: 817132140, states[0] = -12.476824, states[40]= 0.006137
Saving checkpoint... 
Iteration: 828928630, states[0] = -94.508663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 840273298, states[0] = -94.044600, states[40]= 0.000001
Saving checkpoint... 
Iteration: 850352880, states[0] = -94.393751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 860452554, states[0] = -94.522373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 870195651, states[0] = -49.806452, states[40]= 0.002875
Saving checkpoint... 
Iteration: 878901422, states[0] = -94.475046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 888234051, states[0] = -92.754785, states[40]= 0.000002
Saving checkpoint... 
Iteration: 897684469, states[0] = -41.968893, states[40]= 0.006872
Saving checkpoint... 
Iteration: 908242908, states[0] = -93.716017, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917740361, states[0] = -93.631742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 928333253, states[0] = -94.331279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 938457550, states[0] = -94.516466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 948305750, states[0] = -94.223918, states[40]= 0.000001
Saving checkpoint... 
Iteration: 959469541, states[0] = -94.520267, states[40]= 0.000001
Saving checkpoint... 
Iteration: 969539185, states[0] = 32.702784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979593307, states[0] = 11.591886, states[40]= 0.001119
Saving checkpoint... 
Iteration: 989003178, states[0] = 20.576730, states[40]= 0.000130
Saving checkpoint... 
Iteration: 998918199, states[0] = -94.479819, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1010032040, states[0] = 34.238862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020058046, states[0] = 26.698624, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1030826568, states[0] = -94.297551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1041748475, states[0] = -93.793323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1051065211, states[0] = 23.937076, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1059013388, states[0] = 33.666412, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1069181976, states[0] = -40.413470, states[40]= 0.008008
Saving checkpoint... 
Iteration: 1077452756, states[0] = -94.497833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1088210348, states[0] = -62.106794, states[40]= 0.000550
Saving checkpoint... 
Iteration: 1098721544, states[0] = -76.224959, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1109041707, states[0] = 32.049227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117918539, states[0] = -94.466657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1128724475, states[0] = -81.428688, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1137499500, states[0] = -94.511448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146822322, states[0] = -94.269276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156592325, states[0] = 12.068275, states[40]= 0.000998
Saving checkpoint... 
Iteration: 1165016470, states[0] = 34.641244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174888880, states[0] = -94.424557, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1183475943, states[0] = -94.497807, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1192413471, states[0] = -94.453104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1200627320, states[0] = -8.653387, states[40]= 0.006846
Saving checkpoint... 
Iteration: 1211579381, states[0] = 17.989951, states[40]= 0.000210
Saving checkpoint... 
Iteration: 1222692575, states[0] = -47.530960, states[40]= 0.003745
Saving checkpoint... 
Iteration: 1233303803, states[0] = -94.182043, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1242507030, states[0] = 29.087390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249989377, states[0] = -94.495555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1259343487, states[0] = -94.323302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268921697, states[0] = -94.452639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1278490924, states[0] = -94.492891, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1290113996, states[0] = 0.694303, states[40]= 0.006125
Saving checkpoint... 
Iteration: 1301190669, states[0] = -46.166350, states[40]= 0.004369
Saving checkpoint... 
Iteration: 1312369170, states[0] = -94.376063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1321683267, states[0] = -41.223618, states[40]= 0.007367
Saving checkpoint... 
Iteration: 1331217246, states[0] = -69.828546, states[40]= 0.000178
Saving checkpoint... 
Iteration: 1341631902, states[0] = -12.205921, states[40]= 0.006107
Saving checkpoint... 
Iteration: 1350403564, states[0] = -94.424109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1360031931, states[0] = 34.276049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369134551, states[0] = -14.240964, states[40]= 0.006060
Saving checkpoint... 
Iteration: 1377381678, states[0] = -94.390509, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1387071855, states[0] = 21.234670, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1397163389, states[0] = -30.629069, states[40]= 0.018270
Saving checkpoint... 
Iteration: 1408279865, states[0] = -94.026130, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1418589678, states[0] = 13.328554, states[40]= 0.000732
Saving checkpoint... 
Iteration: 1429394705, states[0] = -94.403829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1438282527, states[0] = -94.040157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1447557896, states[0] = 26.775475, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1457237532, states[0] = -93.365961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1467016215, states[0] = 34.597023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477483716, states[0] = -94.467670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1486895327, states[0] = -94.398137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1497655787, states[0] = -27.107785, states[40]= 0.020702
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.346487
 - CaMKt in component CaMK (millimolar): 0.055873
 - cass in component intracellular_ions (millimolar): 0.000105
 - nai in component intracellular_ions (millimolar): 8.579992
 - nass in component intracellular_ions (millimolar): 8.580194
 - ki in component intracellular_ions (millimolar): 142.208759
 - kss in component intracellular_ions (millimolar): 142.208721
 - cansr in component intracellular_ions (millimolar): 2.853013
 - cajsr in component intracellular_ions (millimolar): 2.802619
 - cai in component intracellular_ions (millimolar): 0.000110
 - m in component INa (dimensionless): 0.003827
 - hf in component INa (dimensionless): 0.870026
 - hs in component INa (dimensionless): 0.870013
 - j in component INa (dimensionless): 0.869923
 - hsp in component INa (dimensionless): 0.707254
 - jp in component INa (dimensionless): 0.869852
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.670955
 - hLp in component INaL (dimensionless): 0.381074
 - a in component Ito (dimensionless): 0.000647
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.545002
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.606059
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.862595
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999471
 - jca in component ICaL (dimensionless): 0.999925
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006088
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.451174
 - xs1 in component IKs (dimensionless): 0.345490
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997480
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
09:30:12 (70609): called boinc_finish(0)

</stderr_txt>
]]>


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